ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets

scientific article published on September 2000

ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.BJP.0703517
P8608Fatcat IDrelease_ez5bh7vo55enrexgely3dvphte
P932PMC publication ID1572284
P698PubMed publication ID10960076
P5875ResearchGate publication ID12362054

P2093author name stringR J Evans
M P Mahaut-Smith
M G Rolf
S J Ennion
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Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape changeQ33178933
Role of intracellular signaling events in ADP-induced platelet aggregation.Q33179086
Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null miceQ33903557
Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood plateletsQ34252209
A P2X purinoceptor expressed by a subset of sensory neuronsQ34296113
Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neuronsQ34296118
Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptorQ34388137
The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cellsQ34416899
Towards a revised nomenclature for P1 and P2 receptorsQ34424522
Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in plateletsQ34453608
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Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregationQ36166958
Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human plateletsQ36895115
P2 receptor subtypes in the cardiovascular systemQ36899623
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Overview. Purinergic mechanismsQ37610882
Secretable Storage Pools in PlateletsQ38077642
P2 purinoceptors on vascular endothelial cells: physiological significance and transduction mechanismsQ38148094
An antagonist-insensitive P2X receptor expressed in epithelia and brainQ38362921
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Receptors for ADP on human blood platelets.Q40664358
Agonist action of adenosine triphosphates at the human P2Y1 receptorQ40987858
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Nucleotide receptorsQ41541504
Purinoceptor-evoked calcium signalling in human plateletsQ41682742
Abundant amounts of diadenosine 5′,5‴-P1,P4-tetraphosphate are present and releasable, but metabolically inactive, in human plateletsQ41785105
ADP evokes biphasic Ca2+ influx in fura-2-loaded human platelets. Evidence for Ca2+ entry regulated by the intracellular Ca2+ storeQ41900836
Resting and ADP-evoked changes in cytosolic free sodium concentration in human platelets loaded with the indicator SBFI.Q42470086
ATP derivatives are antagonists of the P2Y1 receptor: similarities to the platelet ADP receptorQ42543394
Rapid ADP-evoked currents in human platelets recorded with the nystatin permeabilized patch techniqueQ43554338
The kinetics of changes in intracellular calcium concentration in fura-2-loaded human plateletsQ44154794
ADP-induced rapid inward currents through Ca(2+)-permeable cation channels in mouse, rat and guinea-pig megakaryocytes: a patch-clamp studyQ46896453
The P2Y1 receptor is necessary for adenosine 5'-diphosphate-induced platelet aggregation.Q47929427
The regulation of vascular function by P2 receptors: multiple sites and multiple receptors.Q54014344
Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.Q54077482
Aggregation of Blood Platelets by Adenosine Diphosphate and its ReversalQ59065336
Intracellular Ca2+ activates phospholipase CQ69073582
Source and concentration of extracellular adenosine triphosphate during haemostasis in rats, rabbits and manQ70623270
Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human plateletsQ71058907
Three cation influx currents activated by purinergic receptor stimulation in rat megakaryocytesQ71675871
Cytoplasmic Ca2+ oscillation in rat megakaryocytes evoked by a novel type of purinoceptorQ72774621
P2Y receptors: in the middle of the roadQ73536421
Characterization of P2x1 purinoreceptors on rat platelets: effect of clopidogrelQ73774599
Presence of P2X1 purinoceptors in human platelets and megakaryoblastic cell linesQ74019347
Depolarization-evoked Ca2+ release in a non-excitable cell, the rat megakaryocyteQ74525935
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)108-114
P577publication date2000-09-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets
P478volume131

Reverse relations

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