Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets

scientific article published on 01 February 1996

Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.271.6.2879
P698PubMed publication ID8621673

P2093author name stringS O Sage
M P Mahaut-Smith
A B MacKenzie
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2879-2881
P577publication date1996-02-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleActivation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets
P478volume271

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cites work (P2860)
Q28513773A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo
Q24673329A study of P2X1 receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors
Q77136382ADP and inositol trisphosphate evoke oscillations of a monovalent cation conductance in rat megakaryocytes
Q28367076ADP and platelets: the end of the beginning
Q35041833ADP can induce aggregation of human platelets via both P2Y(1) and P(2T) receptors
Q41961496ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets
Q40820783ADP-induced platelet aggregation and inhibition of adenylyl cyclase activity stimulated by prostaglandins: signal transduction mechanisms
Q42909234Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors.
Q28345809Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type G(i)-linked P2T antagonist, CS-747
Q26799623Blood cells: an historical account of the roles of purinergic signalling
Q38830299Calcium Signalling through Ligand-Gated Ion Channels such as P2X1 Receptors in the Platelet and other Non-Excitable Cells.
Q80478882Calcium channel blockers increase the amount of nitrite production in rabbits without decreasing the responsiveness of platelets to collagen
Q36166958Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation
Q42081206Contribution of the intracellular C terminal domain to regulation of human P2X1 receptors for ATP by phorbol ester and Gq coupled mGlu(1α) receptors
Q54077482Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.
Q33903557Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice
Q73372512Effects of ATP and derivatives on neuropile glial cells of the leech central nervous system
Q44120735Effects of a P2Y(12) receptor antagonist on the response of equine platelets to ADP. Comparison with human platelets
Q28139562Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells
Q41099787Families of ion channels with two hydrophobic segments
Q34243239Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.
Q38109969Harnessing the platelet signaling network to produce an optimal hemostatic response.
Q38306676Historical perspective on ADP-induced platelet activation
Q39635604Human Platelets Express Functional α7-Nicotinic Acetylcholine Receptors
Q28370741Identification and characterization of P(1), P(7)-Di(adenosine-5')-heptaphosphate from human platelets
Q34496403Identification, characterization, and inhibition of the platelet ADP receptors
Q44689561Inhibition of ADP-induced intracellular Ca2+ responses and platelet aggregation by the P2Y12 receptor antagonists AR-C69931MX and clopidogrel is enhanced by prostaglandin E1.
Q35876629Inhibition of inositol 1,4,5-trisphosphate-induced Ca2+ release by cAMP-dependent protein kinase in a living cell
Q47755338Ligand specificity and ticlopidine effects distinguish three human platelet ADP receptors
Q33334189More pieces of the platelet activation puzzle slide into place
Q77965277No requirement of P2X1 purinoceptors for platelet aggregation
Q41541504Nucleotide receptors
Q36899623P2 receptor subtypes in the cardiovascular system
Q38306634P2 receptors and platelet function
Q50005939P2X1 Receptors Amplify FcγRIIa-Induced Ca2+ Increases and Functional Responses in Human Platelets.
Q24310679P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression
Q35027546P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors
Q28237411Pharmacology of P2X channels
Q77454046Phospholipase A2: its role in ADP- and thrombin-induced platelet activation mechanisms
Q33951830Platelet P2 receptors: from curiosity to clinical targets
Q33686166Platelet dense granules: structure, function and implications for haemostasis.
Q52584016Protein kinase C activates non-capacitative calcium entry in human platelets.
Q36058000Purification and Recognition of Recombinant Mouse P2X(1) Receptors Expressed in a Baculovirus System
Q33420664Purinergic control of inflammation and thrombosis: Role of P2X1 receptors
Q41682742Purinoceptor-evoked calcium signalling in human platelets
Q28354009Ragged spiking of free calcium in ADP-stimulated human platelets: regulation of puff-like calcium signals in vitro and ex vivo
Q77772768Reversible and irreversible intracellular Ca2+ spiking in single isolated human platelets
Q33236096Sp1/3 and NF-1 mediate basal transcription of the human P2X1 gene in megakaryoblastic MEG-01 cells
Q74248188Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells
Q33595771Systems modeling of Ca(2+) homeostasis and mobilization in platelets mediated by IP3 and store-operated Ca(2+) entry
Q38306728The P2X1 receptor and platelet function
Q28634218The P2Y1 receptor mediates ADP-induced p38 kinase-activating factor generation in human platelets
Q40691336The human SH-SY5Y neuroblastoma cell-line expresses a functional P2X7 purinoceptor that modulates voltage-dependent Ca2+ channel function
Q41906079The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties
Q40870844The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets
Q50215851Transcriptomic analysis of the ion channelome of human platelets and megakaryocytic cell lines.
Q54125809cGMP inhibits IP3-induced Ca2+ release in intact rat megakaryocytes via cGMP- and cAMP-dependent protein kinases.

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