Regulation of serotonin receptor function in the nervous system by lipid rafts and adaptor proteins

scientific article published on 06 March 2010

Regulation of serotonin receptor function in the nervous system by lipid rafts and adaptor proteins is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YEXCR.2010.02.034
P698PubMed publication ID20211176

P50authorPer SvenningssonQ21175215
P2093author name stringBenita Sjögren
Karl Björk
P2860cites workFunctional Selectivity and Classical Concepts of Quantitative PharmacologyQ22242288
An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behaviorQ24310712
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signallingQ24321629
Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approachQ24536364
Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivoQ24647416
A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic ReceptorQ27650801
A review of central 5-HT receptors and their functionQ28142963
Role of p11 in cellular and behavioral effects of 5-HT4 receptor stimulationQ28235087
The fluid mosaic model of the structure of cell membranesQ28239890
Transduction of receptor signals by beta-arrestinsQ28246395
Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptorsQ28266342
Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behaviorQ28286238
New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targetingQ28286252
Alterations in 5-HT1B receptor function by p11 in depression-like statesQ28290425
Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variantQ28369138
Synthesis of serotonin by a second tryptophan hydroxylase isoformQ28513857
Lipid rafts as a membrane-organizing principleQ29615727
PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptorsQ30482703
The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteinsQ33198716
Cloning and characterization of a novel human 5-HT4 receptor variant that lacks the alternatively spliced carboxy terminal exon. RT-PCR distribution in human brain and periphery of multiple 5-HT4 receptor variantsQ34105746
New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains.Q34537871
Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptorQ34548751
Beta-arrestin-biased ligands at seven-transmembrane receptorsQ34654662
Efficacy at G-protein-coupled receptorsQ34742798
Multiple functions of caveolin-1.Q34790966
Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stabilityQ35128324
p11 (S100A10)--an inducible adaptor protein that modulates neuronal functionsQ36644963
Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of ParkinsonismQ36883134
Membrane organization and function of the serotonin(1A) receptorQ36915177
Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.Q36954117
Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinasesQ37068810
Signaling at G-protein-coupled serotonin receptors: recent advances and future research directionsQ37233842
Caveolin-1 and lipid microdomains regulate Gs trafficking and attenuate Gs/adenylyl cyclase signalingQ37415804
GPCR interacting proteins (GIPs) in the nervous system: Roles in physiology and pathologiesQ37670210
Localization of the mouse 5-hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling.Q40125652
The PDZ-binding domain is essential for the dendritic targeting of 5-HT2A serotonin receptors in cortical pyramidal neurons in vitro.Q40612091
A direct interaction of PSD-95 with 5-HT2A serotonin receptors regulates receptor trafficking and signal transductionQ40654414
Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalizationQ41238228
Cholesterol reduction attenuates 5-HT1A receptor-mediated signaling in human primary neuronal cultures.Q43573099
A role for caveolin-1 in post-injury reactive neuronal plasticityQ45247880
Targeting of the 5-HT1A serotonin receptor to neuronal dendrites is mediated by Yif1B.Q46442160
Do caveolins regulate cells by actions outside of caveolae?Q46857744
Caveolin-1 affects serotonin binding and cell surface levels of human 5-HT7(a) receptorsQ46950657
Localization of monoamines in the lower brain stem.Q51272663
Depletion of the lipid raft constituents, sphingomyelin and ganglioside, decreases serotonin binding at human 5-HT7(a)receptors in HeLa cellsQ57374111
Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptorsQ79300301
Crystalline SerotoninQ80924613
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectserotoninQ167934
nervous systemQ9404
membrane raftQ424178
P304page(s)1351-1356
P577publication date2010-03-06
P1433published inExperimental Cell ResearchQ1524289
P1476titleRegulation of serotonin receptor function in the nervous system by lipid rafts and adaptor proteins
P478volume316

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cites work (P2860)
Q87427318A new vesicular scaffolding complex mediates the G-protein-coupled 5-HT1A receptor targeting to neuronal dendrites
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Q38574561The Deleterious Effects of Oxidative and Nitrosative Stress on Palmitoylation, Membrane Lipid Rafts and Lipid-Based Cellular Signalling: New Drug Targets in Neuroimmune Disorders.

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