| scholarly article | Q13442814 |
| P50 | author | Gaynor A Smith | Q42215544 |
| Penelope J. Hallett | Q42215555 | ||
| George K Tofaris | Q56056700 | ||
| Thomas G Moens | Q57161565 | ||
| Ole Isacson | Q67215582 | ||
| P2093 | author name string | Alfred L Goldberg | |
| Ji-Long Liu | |||
| Hyoung Tae Kim | |||
| Emily Mangano | |||
| Sian E Davies | |||
| P2860 | cites work | Physiological and pathological properties of alpha-synuclein | Q36866952 |
| Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo. | Q37102231 | ||
| Dynamic changes in presynaptic and axonal transport proteins combined with striatal neuroinflammation precede dopaminergic neuronal loss in a rat model of AAV alpha-synucleinopathy. | Q37221349 | ||
| Genomic investigation of alpha-synuclein multiplication and parkinsonism | Q37362778 | ||
| Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation | Q37403103 | ||
| Lysosome-dependent pathways as a unifying theme in Parkinson's disease. | Q38038561 | ||
| New stereological methods for counting neurons | Q40843719 | ||
| alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome | Q43816254 | ||
| Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease | Q43874109 | ||
| α-Synuclein Is Degraded by Both Autophagy and the Proteasome | Q44420467 | ||
| Drosophila Nedd4, a ubiquitin ligase, is recruited by Commissureless to control cell surface levels of the roundabout receptor | Q47072568 | ||
| Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. | Q48586171 | ||
| Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease | Q57977634 | ||
| Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression | Q22001521 | ||
| Dopamine covalently modifies and functionally inactivates parkin | Q24338423 | ||
| Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition | Q24598118 | ||
| Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. | Q24634577 | ||
| HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS | Q28306195 | ||
| A Drosophila model of Parkinson's disease | Q29617052 | ||
| Physiological functions of the HECT family of ubiquitin ligases | Q29617293 | ||
| α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies | Q30471591 | ||
| A nonconserved Ala401 in the yeast Rsp5 ubiquitin ligase is involved in degradation of Gap1 permease and stress-induced abnormal proteins | Q33193077 | ||
| Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury. | Q33249022 | ||
| Whole genome survey of coding SNPs reveals a reproducible pathway determinant of Parkinson disease | Q33375794 | ||
| A splice isoform of DNedd4, DNedd4-long, negatively regulates neuromuscular synaptogenesis and viability in Drosophila | Q34081449 | ||
| Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein | Q34281429 | ||
| Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation | Q34325576 | ||
| Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. | Q34380191 | ||
| Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. | Q34394747 | ||
| CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy | Q35122963 | ||
| Ubiquitin ligase Nedd4 promotes alpha-synuclein degradation by the endosomal-lysosomal pathway | Q35344983 | ||
| Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning | Q35771011 | ||
| P921 | main subject | Parkinson's disease | Q11085 |
| Synuclein | Q24767155 | ||
| P304 | page(s) | 79-87 | |
| P577 | publication date | 2013-12-31 | |
| P1433 | published in | Neurobiology of Disease | Q15716606 |
| P1476 | title | Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease | |
| P478 | volume | 64 |
| Q47157967 | A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson's Disease. |
| Q37181996 | Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease. |
| Q28547585 | Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug Screening |
| Q41113409 | Glutamine promotes Hsp70 and inhibits α-Synuclein accumulation in pheochromocytoma PC12 cells |
| Q38790881 | How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease? |
| Q92086130 | Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease |
| Q37644778 | Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease |
| Q34073890 | Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein |
| Q85205683 | Lysosomes to combat Parkinson's disease |
| Q54114687 | Modeling Parkinson's Disease in Drosophila: What Have We Learned for Dominant Traits? |
| Q39104462 | Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds |
| Q26823894 | Retrograde labeling, transduction, and genetic targeting allow cellular analysis of corticospinal motor neurons: implications in health and disease |
| Q35510197 | Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease. |
| Q90073258 | Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts |
| Q64102410 | The Roles of Post-translational Modifications on α-Synuclein in the Pathogenesis of Parkinson's Diseases |
| Q51284194 | The Transcellular Propagation and Intracellular Trafficking of α-Synuclein. |
| Q90315659 | Ubiquitination of alpha-synuclein filaments by Nedd4 ligases |
| Q59806475 | α-Synuclein Trafficking in Parkinson's Disease: Insights From Fly and Mouse Models |
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