review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Jonathan M Scholey | Q114513705 |
Gul Civelekoglu-Scholey | Q115279160 | ||
P2860 | cites work | CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase | Q24302159 |
Architecture of the human ndc80-hec1 complex, a critical constituent of the outer kinetochore | Q24305358 | ||
Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis | Q24315967 | ||
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore | Q24320105 | ||
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility | Q24601419 | ||
All kinesin superfamily protein, KIF, genes in mouse and human | Q24632779 | ||
A bipolar kinesin | Q24633398 | ||
A "slow" homotetrameric kinesin-related motor protein purified from Drosophila embryos | Q24634178 | ||
Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres | Q24649746 | ||
Kinetochore dynein is required for chromosome motion and congression independent of the spindle checkpoint | Q24649800 | ||
The kinesin-like protein KLP61F is essential for mitosis in Drosophila | Q24651223 | ||
Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation | Q24652311 | ||
The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment | Q24653914 | ||
Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro | Q24669545 | ||
Mitotic centromere-associated kinesin is important for anaphase chromosome segregation | Q24670465 | ||
The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles | Q24670581 | ||
[Polarization optical studies of the mitotic spindle. I. The demonstration of spindle fibers in living cells] | Q73252573 | ||
Measurement of the force-velocity relation for growing microtubules | Q73823827 | ||
Fluorescent speckle microscopy of spindle microtubule assembly and motility in living cells | Q77801943 | ||
Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore | Q24682934 | ||
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex | Q27324199 | ||
Chromosomes can congress to the metaphase plate before biorientation | Q27332199 | ||
Structure of the Kinesin13-Microtubule Ring Complex | Q27652865 | ||
ATPase Cycle of the Nonmotile Kinesin NOD Allows Microtubule End Tracking and Drives Chromosome Movement | Q27653383 | ||
Time-lapse microscopy reveals unique roles for kinesins during anaphase in budding yeast | Q27930346 | ||
Novel roles for saccharomyces cerevisiae mitotic spindle motors | Q27934047 | ||
Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules | Q27938562 | ||
Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase | Q28235011 | ||
Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments | Q28236606 | ||
The depolymerizing kinesin MCAK uses lattice diffusion to rapidly target microtubule ends | Q28238186 | ||
Dynamic instability of microtubule growth | Q29547522 | ||
Mitotic spindle organization by a plus-end-directed microtubule motor | Q29616139 | ||
High-resolution model of the microtubule | Q29618379 | ||
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1 | Q29618389 | ||
Kinesin-related proteins required for structural integrity of the mitotic spindle | Q29636252 | ||
Protein architecture of the human kinetochore microtubule attachment site | Q30436130 | ||
The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work | Q30450974 | ||
Microtubule flux and sliding in mitotic spindles of Drosophila embryos | Q30476615 | ||
Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis | Q30477305 | ||
Functional coordination of three mitotic motors in Drosophila embryos | Q30477413 | ||
Quantitative analysis of an anaphase B switch: predicted role for a microtubule catastrophe gradient | Q30480485 | ||
Kinesin-13s form rings around microtubules | Q30480526 | ||
Dynamic partitioning of mitotic kinesin-5 cross-linkers between microtubule-bound and freely diffusing states. | Q30482990 | ||
Kinesin-5-dependent poleward flux and spindle length control in Drosophila embryo mitosis | Q30486464 | ||
Ncd motor binding and transport in the spindle | Q30487273 | ||
Microtubule cytoskeleton remodeling by acentriolar microtubule-organizing centers at the entry and exit from mitosis in Drosophila somatic cells | Q30487858 | ||
The distribution of polar ejection forces determines the amplitude of chromosome directional instability | Q30488889 | ||
The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion | Q30490445 | ||
Kinesin-5 acts as a brake in anaphase spindle elongation | Q30491649 | ||
The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement | Q30491665 | ||
Chromosome congression in the absence of kinetochore fibres | Q30495251 | ||
The Drosophila kinesin-like protein KLP67A is essential for mitotic and male meiotic spindle assembly | Q30499485 | ||
Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo | Q30654911 | ||
Model for anaphase B: role of three mitotic motors in a switch from poleward flux to spindle elongation | Q30835545 | ||
Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics | Q36322983 | ||
The roles of microtubule-based motor proteins in mitosis: comprehensive RNAi analysis in the Drosophila S2 cell line | Q36323349 | ||
Roles of kinesin and kinesin-like proteins in sea urchin embryonic cell division: evaluation using antibody microinjection | Q36383220 | ||
Inhibition of anaphase spindle elongation in vitro by a peptide antibody that recognizes kinesin motor domain | Q36421849 | ||
Cell motility by labile association of molecules. The nature of mitotic spindle fibers and their role in chromosome movement | Q36427621 | ||
Chromosome motion during attachment to the vertebrate spindle: initial saltatory-like behavior of chromosomes and quantitative analysis of force production by nascent kinetochore fibers | Q36529708 | ||
Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts. | Q36531791 | ||
Kinetochore microtubules in PTK cells | Q36533211 | ||
CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether | Q36625807 | ||
Modeling of chromosome motility during mitosis. | Q36625814 | ||
Poleward transport of Eg5 by dynein-dynactin in Xenopus laevis egg extract spindles | Q36843155 | ||
Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment | Q36890066 | ||
Synchronizing chromosome segregation by flux-dependent force equalization at kinetochores. | Q37267720 | ||
Motor domain phosphorylation and regulation of the Drosophila kinesin 13, KLP10A. | Q37323122 | ||
Fibrils connect microtubule tips with kinetochores: a mechanism to couple tubulin dynamics to chromosome motion. | Q37353009 | ||
Dynein antagonizes eg5 by crosslinking and sliding antiparallel microtubules | Q37440564 | ||
Theoretical problems related to the attachment of microtubules to kinetochores | Q37545521 | ||
Identification and partial characterization of six members of the kinesin superfamily in Drosophila | Q37597638 | ||
Force and length in the mitotic spindle | Q37631261 | ||
New look inside the spindle: microtubule-dependent microtubule generation within the spindle | Q37659553 | ||
An essential bipolar mitotic motor | Q38970539 | ||
The forces that move chromosomes in mitosis | Q39653525 | ||
A simple, mechanistic model for directional instability during mitotic chromosome movements | Q40209278 | ||
Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins | Q40358374 | ||
Functionally distinct kinesin-13 family members cooperate to regulate microtubule dynamics during interphase. | Q40456129 | ||
Phospho-regulated interaction between kinesin-6 Klp9p and microtubule bundler Ase1p promotes spindle elongation. | Q41193119 | ||
Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence | Q41583375 | ||
Chromosome elasticity and mitotic polar ejection force measured in living Drosophila embryos by four-dimensional microscopy-based motion analysis | Q44039726 | ||
The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends | Q44348888 | ||
Identification of microtubule binding sites in the Ncd tail domain | Q44856733 | ||
Activating and silencing the mitotic checkpoint through CENP-E-dependent activation/inactivation of BubR1. | Q45952803 | ||
Kinetic analysis of mitotic spindle elongation in vitro. | Q46007717 | ||
Kin I kinesins are microtubule-destabilizing enzymes | Q46042447 | ||
SnapShot: motor proteins in spindle assembly | Q46218283 | ||
Interphase chromosomes undergo constrained diffusional motion in living cells | Q46252294 | ||
A homotetrameric kinesin-5, KLP61F, bundles microtubules and antagonizes Ncd in motility assays | Q46303403 | ||
Isolation of a sea urchin egg kinesin-related protein using peptide antibodies | Q46744079 | ||
Drosophila Klp67A is required for proper chromosome congression and segregation during meiosis I. | Q47072781 | ||
The mitotic kinesin-14 Ncd drives directional microtubule-microtubule sliding | Q47833249 | ||
Arrangement of subunits in flagellar microtubules. | Q47866991 | ||
Dynein: A Protein with Adenosine Triphosphatase Activity from Cilia | Q47891476 | ||
Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning | Q48074617 | ||
Retrograde transport by the microtubule-associated protein MAP 1C. | Q48183505 | ||
Opposite end assembly and disassembly of microtubules at steady state in vitro | Q48231342 | ||
Structural studies on porcine brain tubulin in extended sheets | Q48256687 | ||
Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations | Q48726718 | ||
Minus-end-directed motor Ncd exhibits processive movement that is enhanced by microtubule bundling in vitro. | Q50649458 | ||
Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis. | Q52123192 | ||
Minus-end-directed motion of kinesin-coated microspheres driven by microtubule depolymerization. | Q52210566 | ||
The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor. | Q52239281 | ||
Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans. | Q52254905 | ||
The Drosophila claret segregation protein is a minus-end directed motor molecule. | Q52449568 | ||
Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos. | Q52599609 | ||
Architecture of the microtubule component of mitotic spindles from Dictyostelium discoideum. | Q52872528 | ||
Attachment of transported vesicles to microtubules in axoplasm is facilitated by AMP-PNP. | Q54039178 | ||
Identification of kinesin in sea urchin eggs and evidence for its localization in the mitotic spindle | Q59082527 | ||
Kinesin-8 Motors Act Cooperatively to Mediate Length-Dependent Microtubule Depolymerization | Q60193585 | ||
Klp67A destabilises pre-anaphase microtubules but subsequently is required to stabilise the central spindle | Q60227680 | ||
Microtubule dynamics in the chromosomal spindle fiber: analysis by fluorescence and high-resolution polarization microscopy | Q67950302 | ||
Direct visualization of microtubule flux during metaphase and anaphase in crane-fly spermatocytes | Q30839538 | ||
Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations | Q30856494 | ||
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks | Q33214719 | ||
Force production by disassembling microtubules | Q33227340 | ||
The homotetrameric kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations | Q33390650 | ||
Chromosome motors on the move. From motion to spindle checkpoint activity | Q33757574 | ||
Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos | Q33880076 | ||
Tension-dependent regulation of microtubule dynamics at kinetochores can explain metaphase congression in yeast | Q33911156 | ||
Cytoplasmic dynein is required for poleward chromosome movement during mitosis in Drosophila embryos | Q33930488 | ||
Two related kinesins, klp5+ and klp6+, foster microtubule disassembly and are required for meiosis in fission yeast | Q33948791 | ||
Microtubule motors in mitosis | Q34036578 | ||
Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans | Q34169213 | ||
Clamped-filament elongation model for actin-based motors | Q34177114 | ||
A force balance model of early spindle pole separation in Drosophila embryos. | Q34180288 | ||
The dynamic kinetochore-microtubule interface | Q34362671 | ||
Theoretical studies on oscillations in microtubule polymerization | Q34370983 | ||
Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein | Q34507133 | ||
Slide-and-cluster models for spindle assembly | Q34663861 | ||
Polymer motors: pushing out the front and pulling up the back | Q35295016 | ||
Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes | Q36118138 | ||
Mechanism and function of poleward flux in Xenopus extract meiotic spindles | Q36129388 | ||
The mechanism of action of colchicine. Colchicine binding to sea urchin eggs and the mitotic apparatus | Q36189164 | ||
The mechanism of action of colchicine. Binding of colchincine-3H to cellular protein | Q36189186 | ||
Cross-sectional structure of the central mitotic spindle of Diatoma vulgare. Evidence for specific interactions between antiparallel microtubules | Q36203857 | ||
Structural polarity of kinetochore microtubules in PtK1 cells | Q36204428 | ||
Measurements of the force produced by the mitotic spindle in anaphase | Q36207654 | ||
Tubulin dynamics in cultured mammalian cells | Q36212188 | ||
Interzone microtubule behavior in late anaphase and telophase spindles | Q36217377 | ||
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties | Q36217545 | ||
Three-dimensional reconstruction and analysis of mitotic spindles from the yeast, Schizosaccharomyces pombe | Q36232215 | ||
Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro | Q36235181 | ||
Kinetochore microtubule dynamics and the metaphase-anaphase transition | Q36236166 | ||
Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix | Q36294036 | ||
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles | Q36322575 | ||
P433 | issue | 13 | |
P304 | page(s) | 2231-2250 | |
P577 | publication date | 2010-03-10 | |
P1433 | published in | Cellular and Molecular Life Sciences | Q5058352 |
P1476 | title | Mitotic force generators and chromosome segregation | |
P478 | volume | 67 |
Q53254699 | 50 ways to build a spindle: the complexity of microtubule generation during mitosis. |
Q37901782 | A hitchhiker's guide to mechanobiology |
Q30556991 | A spindle-independent cleavage pathway controls germ cell formation in Drosophila |
Q35841722 | A stochastic model of kinetochore-microtubule attachment accurately describes fission yeast chromosome segregation. |
Q30423655 | An improved optical tweezers assay for measuring the force generation of single kinesin molecules |
Q28078705 | Anaphase B |
Q35610652 | Biophysics of mitosis |
Q54978335 | Complete microtubule-kinetochore occupancy favours the segregation of merotelic attachments. |
Q34197685 | Control of MCAK degradation and removal from centromeres |
Q30846031 | Eg5 restricts anaphase B spindle elongation in mammalian cells |
Q30497659 | Finding the cell center by a balance of dynein and myosin pulling and microtubule pushing: a computational study |
Q43181885 | Force Generation by Molecular-Motor-Powered Microtubule Bundles; Implications for Neuronal Polarization and Growth |
Q34504982 | Force is a signal that cells cannot ignore |
Q34029275 | Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest |
Q64244923 | Impaired CENP-E Function Renders Large Chromosomes More Vulnerable to Congression Failure |
Q28070192 | In silico bone mechanobiology: modeling a multifaceted biological system |
Q47611167 | Ligand- and structure-based in silico studies to identify kinesin spindle protein (KSP) inhibitors as potential anticancer agents |
Q89693406 | Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling |
Q37728166 | Mechanisms to Avoid and Correct Erroneous Kinetochore-Microtubule Attachments |
Q34306884 | Mitotic Membrane Helps to Focus and Stabilize the Mitotic Spindle |
Q53236078 | Multi-talented MCAK: Microtubule depolymerizer with a strong grip. |
Q24633853 | New insights into mechanisms of resistance to microtubule inhibitors |
Q55362956 | Non-random Mis-segregation of Human Chromosomes. |
Q28742174 | Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B |
Q51538586 | Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets. |
Q39084479 | Roles of the cytoskeleton, cell adhesion and rho signalling in mechanosensing and mechanotransduction. |
Q24293546 | Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochores |
Q38339096 | The emergence of sarcomeric, graded-polarity and spindle-like patterns in bundles of short cytoskeletal polymers and two opposite molecular motors |
Q90211332 | Theory of Cytoskeletal Reorganization during Cross-Linker-Mediated Mitotic Spindle Assembly |
Q35840488 | Unconventional functions of microtubule motors |
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