Galectin-3 supports stemness in ovarian cancer stem cells by activation of the Notch1 intracellular domain.

scientific article published on 09 September 2016

Galectin-3 supports stemness in ovarian cancer stem cells by activation of the Notch1 intracellular domain. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.11920
P932PMC publication ID5356551
P698PubMed publication ID27626163

P50authorKyung-Hee ChunQ83476796
P2093author name stringWonhee Jang
Seok-Jun Kim
Junghyun Jung
Hyeok Gu Kang
Yunhee Cho
Da-Hyun Kim
P2860cites workIdentification and characterization of ovarian cancer-initiating cells from primary human tumorsQ24644329
The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theoryQ33739695
Galectin-3 facilitates cell motility in gastric cancer by up-regulating protease-activated receptor-1 (PAR-1) and matrix metalloproteinase-1 (MMP-1).Q34037992
Ablation of galectin-3 induces p27(KIP1)-dependent premature senescence without oncogenic stressQ34413483
Cancer stem cells in solid tumors: an overview and new approaches for their isolation and characterizationQ34424921
Notch signaling in serous ovarian cancerQ34491211
Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2.Q34569371
Glucose deprivation triggers protein kinase C-dependent β-catenin proteasomal degradation.Q35352122
Microenvironment and pathogenesis of epithelial ovarian cancerQ35419057
The role of Notch in tumorigenesis: oncogene or tumour suppressor?Q35564593
Galectin-3 augments tumor initiating property and tumorigenicity of lung cancer through interaction with β-cateninQ35741579
Cleaved CD44 intracellular domain supports activation of stemness factors and promotes tumorigenesis of breast cancerQ35832214
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical updateQ35904534
Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression.Q36074071
Phosphorylation-dependent regulation of Notch1 signaling: the fulcrum of Notch1 signalingQ36078480
The Notch pathway in ovarian carcinomas and adenomas.Q36615348
Evaluating the progenitor cells of ovarian cancer: analysis of current animal models.Q36916354
Mitochondrial metabolism in cancer stem cells: a therapeutic target for colon cancerQ37013799
Effect of respiratory syncytial virus on the growth of hepatocellular carcinoma cell-linesQ37013811
Cancer stem cells--old concepts, new insights.Q37079713
Surgical management of recurrent ovarian cancerQ37426892
Targeting the WEE1 kinase as a molecular targeted therapy for gastric cancerQ37580332
Ablation of human telomerase reverse transcriptase (hTERT) induces cellular senescence in gastric cancer through a galectin-3 dependent mechanism.Q37636765
Notch 1 signaling is active in ovarian cancer.Q37671175
Targeting notch signaling pathway in cancer: clinical development advances and challengesQ37696748
Cancerous ovarian stem cells: obscure targets for therapy but relevant to chemoresistance.Q38034167
Ovarian cancer: diagnostic, biological and prognostic aspectsQ38261795
Galectin-3 modulates the EGFR signalling-mediated regulation of Sox2 expression via c-Myc in lung cancerQ38829578
Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancerQ38893164
Galectin-3 inhibition suppresses drug resistance, motility, invasion and angiogenic potential in ovarian cancerQ38950425
STAT3 silencing enhances the efficacy of the HSV.tk suicide gene in gastrointestinal cancer therapy.Q39393385
Overexpression of Galectin-3 and its clinical significance in ovarian carcinoma.Q39590802
Galectin-3 increases gastric cancer cell motility by up-regulating fascin-1 expressionQ39789149
Galectin-3 may contribute to Cisplatin resistance in clear cell carcinoma of the ovaryQ40145990
Identification of L1CAM, Jagged2 and Neuromedin U as ovarian cancer-associated antigens.Q40459498
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysisQ40552203
Ovarian cancer stem cells: a new target for cancer therapyQ42092160
Galectin-3 germline variant at position 191 enhances nuclear accumulation and activation of β-catenin in gastric cancerQ42730725
Galectin-3 activates PPARγ and supports white adipose tissue formation and high-fat diet-induced obesity.Q42834230
Unravelling cancer stem cell potential.Q53089167
P433issue42
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
neoplastic stem cellsQ1638475
P304page(s)68229-68241
P577publication date2016-10-01
P1433published inOncotargetQ1573155
P1476titleGalectin-3 supports stemness in ovarian cancer stem cells by activation of the Notch1 intracellular domain
P478volume7

Reverse relations

cites work (P2860)
Q46024099Antibodies Against Specific MUC16 Glycosylation Sites Inhibit Ovarian Cancer Growth.
Q47277352Dietary compound proanthocyanidins from Chinese bayberry (Myrica rubra Sieb. et Zucc.) leaves attenuate chemotherapy-resistant ovarian cancer stem cell traits via targeting the Wnt/β-catenin signaling pathway and inducing G1 cell cycle arrest
Q90639151Early Hyperbaric Oxygen Treatment Attenuates Burn-Induced Neuroinflammation by Inhibiting the Galectin-3-Dependent Toll-Like Receptor-4 Pathway in a Rat Model
Q47249097Galectin 3 expression in primary oral squamous cell carcinomas.
Q41472543Galectin-3 acts as an angiogenic switch to induce tumor angiogenesis via Jagged-1/Notch activation
Q47190193Galectin-3 and Cancer Stemness.
Q90073141Galectin-3 as a Next-Generation Biomarker for Detecting Early Stage of Various Diseases
Q90751205MiR-424-3p suppresses galectin-3 expression and sensitizes ovarian cancer cells to cisplatin
Q91862384Morin decreases galectin-3 expression and sensitizes ovarian cancer cells to cisplatin
Q90333296Non-classical role of Galectin-3 in cancer progression: Translocation to nucleus by carbohydrate-recognition independent manner
Q60947507Pancreatic cancer stem cells: Perspectives on potential therapeutic approaches of pancreatic ductal adenocarcinoma
Q33779227Prognostic roles of Notch receptor mRNA expression in human ovarian cancer
Q90265181Research Progresses in Cancer Stem Cells of Three Common Fertility-Related Female Malignancies
Q33760199The Many Roles of Galectin-3, a Multifaceted Molecule, in Innate Immune Responses against Pathogens.
Q60312794The Role of Galectins in Tumor Progression, Treatment and Prognosis of Gynecological Cancers
Q91910450Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis
Q92759845poFUT1 promotes endometrial decidualization by enhancing the O-fucosylation of Notch1

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