review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0079-6123(09)17909-8 |
P698 | PubMed publication ID | 20302820 |
P2093 | author name string | Hanna Jaaro-Peled | |
P2860 | cites work | DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation | Q24305439 |
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia | Q24306904 | ||
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling | Q24322974 | ||
Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Q24535773 | ||
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth | Q24541302 | ||
Neuregulin 1 and susceptibility to schizophrenia | Q24616921 | ||
Disruption of two novel genes by a translocation co-segregating with schizophrenia | Q28144559 | ||
Antidepressant-like effects in various mice strains in the forced swimming test. | Q44325070 | ||
Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia. | Q44824095 | ||
Neuregulin-1 immunoglobulin-like domain mutant mice: clozapine sensitivity and impaired latent inhibition | Q45261553 | ||
Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1. | Q46302011 | ||
Behavioral characteristics of a nervous system-specific erbB4 knock-out mouse | Q46523281 | ||
Behavioral phenotypes of Disc1 missense mutations in mice | Q48178658 | ||
Phenotypic characterization of spatial cognition and social behavior in mice with 'knockout' of the schizophrenia risk gene neuregulin 1. | Q48400355 | ||
Sexually dimorphic changes in the exploratory and habituation profiles of heterozygous neuregulin-1 knockout mice | Q48463807 | ||
DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex | Q48516263 | ||
Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development. | Q51040069 | ||
Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia. | Q51738410 | ||
Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice | Q64018589 | ||
Interfrontal commissural abnormality in schizophrenia: tractography-assisted callosal parcellation | Q81330445 | ||
Genetics. Two genes link two distinct psychoses | Q81491935 | ||
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth | Q28188775 | ||
The DISC locus in psychiatric illness | Q28251868 | ||
The genetics and biology of DISC1--an emerging role in psychosis and cognition | Q28252172 | ||
Association within a family of a balanced autosomal translocation with major mental illness | Q28257476 | ||
DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling | Q28282412 | ||
Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology | Q28294217 | ||
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain | Q28507787 | ||
DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1 | Q28576213 | ||
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development | Q28582746 | ||
Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components | Q28585466 | ||
Cortical inhibitory neurons and schizophrenia | Q29547683 | ||
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia | Q29618963 | ||
Control of memory formation through regulated expression of a CaMKII transgene | Q29619261 | ||
Construct Validity of the Animal Latent Inhibition Model of Selective Attention Deficits in Schizophrenia | Q30048705 | ||
Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly. | Q30489568 | ||
The family of sensorimotor gating disorders: comorbidities or diagnostic overlaps? | Q30490231 | ||
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans | Q30496743 | ||
Cross-species studies of sensorimotor gating of the startle reflex | Q33692772 | ||
Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice | Q34217453 | ||
Neuregulin and ErbB receptor signaling pathways in the nervous system | Q34278032 | ||
Brain morphology in first-episode schizophrenia: a meta-analysis of quantitative magnetic resonance imaging studies | Q34479485 | ||
Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice | Q34574484 | ||
Preclinical models: status of basic research in depression | Q34934319 | ||
Neuregulins: functions, forms, and signaling strategies | Q35089314 | ||
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice | Q36156959 | ||
A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions | Q36517223 | ||
Modeling madness in mice: one piece at a time | Q36610374 | ||
A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition | Q36657533 | ||
Role of DISC1 in neural development and schizophrenia | Q36720430 | ||
Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain | Q36893742 | ||
Modeling cognitive endophenotypes of schizophrenia in mice | Q37055287 | ||
Neuregulin 1 in neural development, synaptic plasticity and schizophrenia | Q37163033 | ||
Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. | Q37588242 | ||
Behavioral profile of a heterozygous mutant mouse model for EGF-like domain neuregulin 1. | Q40054801 | ||
Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1). | Q44264433 | ||
P921 | main subject | schizophrenia | Q41112 |
P304 | page(s) | 75-86 | |
P577 | publication date | 2009-11-20 | |
P1433 | published in | Progress in Brain Research | Q15800382 |
P1476 | title | Gene models of schizophrenia: DISC1 mouse models | |
P478 | volume | 179 |
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Q30462828 | Animal models of schizophrenia. |
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Q27021774 | DISC1 mouse models as a tool to decipher gene-environment interactions in psychiatric disorders |
Q37061724 | DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. |
Q36092137 | Disordered ripples are a common feature of genetically distinct mouse models relevant to schizophrenia |
Q35172666 | Disrupted-in-schizophrenia 1 (DISC1) regulates dysbindin function by enhancing its stability |
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Q30432973 | Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders |
Q27302920 | Missense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in mice |
Q37968206 | Modeling human neurodegenerative diseases in transgenic systems |
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Q28505294 | Neuroanatomical and behavioral deficits in mice haploinsufficient for Pericentriolar material 1 (Pcm1). |
Q34675943 | Neurodevelopment, GABA system dysfunction, and schizophrenia |
Q34423863 | Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia |
Q46038979 | Preclinical evaluation of non-imidazole histamine H3 receptor antagonists in comparison to atypical antipsychotics for the treatment of cognitive deficits associated with schizophrenia. |
Q48304761 | Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice |
Q35909867 | Schizophrenia: a pathogenetic autoimmune disease caused by viruses and pathogens and dependent on genes. |
Q34845881 | Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells |
Q50421768 | The Histamine H3 Receptor Antagonist DL77 Ameliorates MK801-Induced Memory Deficits in Rats |
Q42691812 | The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats |
Q35675159 | The NMDA receptor co-agonists, D-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex. |
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