Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.

scientific article

Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1049536157
P356DOI10.1038/MP.2008.101
P932PMC publication ID2727926
P698PubMed publication ID18762802

P2093author name stringA Kamiya
T Ando
T Hai
A Sawa
A Hayashi
H Toda
N Ishida
Y Maruyama
T Tomoda
H Mochizuki
M Shimoda
K Ishizuka
M Fujimuro
K Honjo
K Furukubo-Tokunaga
L A Makuch
N G Cascella
N Sawamura
T Sawamura-Yamamoto
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DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutationQ24305439
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowthQ24541302
Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response elementQ24561653
Site-directed mutagenesis by overlap extension using the polymerase chain reactionQ27860503
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowthQ28188775
Evolutionary constraints on the Disrupted in Schizophrenia locusQ28207935
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex developmentQ28582746
Biological roles and mechanistic actions of co-repressor complexesQ28640957
An integrated stress response regulates amino acid metabolism and resistance to oxidative stressQ29547441
CRM1 is responsible for intracellular transport mediated by the nuclear export signalQ29547861
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant actionQ29615696
A Drosophila model of Parkinson's diseaseQ29617052
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergenceQ29618819
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatumQ29620475
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humansQ30496743
A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse.Q33762395
The need for a simple animal model to understand sleepQ33869429
Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorderQ33910429
The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasisQ34085639
The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases.Q34334999
The remote roots of consciousness in fruit-fly selective attention?Q34394981
Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site.Q34407305
A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegenerationQ34562996
Post-translational modifications regulate the ticking of the circadian clock.Q34605395
The cryptocephal gene (ATF4) encodes multiple basic-leucine zipper proteins controlling molting and metamorphosis in Drosophila.Q34610035
Animal sleep: a review of sleep duration across phylogenyQ34710797
Pharmacogenetic rescue in time and space of the rutabaga memory impairment by using Gene-Switch.Q35122058
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in miceQ36156959
Sleep disturbance in schizophreniaQ36272532
Drosophila as a model for human neurodegenerative diseaseQ36312196
Disrupted in schizophrenia 1: building brains and memoriesQ36470351
A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditionsQ36517223
Sleep disorders in psychiatryQ36595659
Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell deathQ36605673
Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnessesQ36690868
Activating transcription factor 4 is translationally regulated by hypoxic stressQ37349289
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteinsQ39391393
Analysis of heat-shock protein�70 gene polymorphisms and the risk of Parkinson?s diseaseQ40618665
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's diseaseQ43874109
Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structureQ44220427
Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1).Q44264433
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in DrosophilaQ44662134
Essentials of sleep recordings in Drosophila: moving beyond sleep time.Q45989237
Dopaminergic modulation of arousal in DrosophilaQ46179218
Drosophila melanogaster: an insect model for fundamental studies of sleepQ46427470
A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasisQ47071522
Embryonic and larval development of the Drosophila mushroom bodies: concentric layer subdivisions and the role of fasciclin II.Q47071896
Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria.Q47715169
Uncoupling of brain activity from movement defines arousal States in DrosophilaQ48088457
Conserved cis-regulatory modules mediate complex neural expression patterns of the eyeless gene in the Drosophila brainQ48168220
Behavioral phenotypes of Disc1 missense mutations in miceQ48178658
Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.Q48196721
Primate disrupted-in-schizophrenia-1 (DISC1): high divergence of a gene for major mental illnesses in recent evolutionary history.Q48423691
Electrophysiological correlates of rest and activity in Drosophila melanogasterQ48441456
Sleep in Drosophila is regulated by adult mushroom bodiesQ48497891
A dynamic role for the mushroom bodies in promoting sleep in DrosophilaQ48497900
DISC1 immunoreactivity at the light and ultrastructural level in the human neocortexQ48516263
Correlates of sleep and waking in Drosophila melanogasterQ48729010
Rest in Drosophila is a sleep-like stateQ48729018
Association of DISC1 with autism and Asperger syndromeQ50313353
Human neurodegenerative disease modeling using Drosophila.Q52605243
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectsleepQ35831
P304page(s)1138-48, 1069
P577publication date2008-09-02
P1433published inMolecular PsychiatryQ6895973
P1476titleNuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.
P478volume13

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cites work (P2860)
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