scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1049536157 |
P356 | DOI | 10.1038/MP.2008.101 |
P932 | PMC publication ID | 2727926 |
P698 | PubMed publication ID | 18762802 |
P2093 | author name string | A Kamiya | |
T Ando | |||
T Hai | |||
A Sawa | |||
A Hayashi | |||
H Toda | |||
N Ishida | |||
Y Maruyama | |||
T Tomoda | |||
H Mochizuki | |||
M Shimoda | |||
K Ishizuka | |||
M Fujimuro | |||
K Honjo | |||
K Furukubo-Tokunaga | |||
L A Makuch | |||
N G Cascella | |||
N Sawamura | |||
T Sawamura-Yamamoto | |||
P2860 | cites work | Mushroom body memoir: from maps to models | Q22337225 |
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation | Q24305439 | ||
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth | Q24541302 | ||
Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element | Q24561653 | ||
Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Q27860503 | ||
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth | Q28188775 | ||
Evolutionary constraints on the Disrupted in Schizophrenia locus | Q28207935 | ||
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development | Q28582746 | ||
Biological roles and mechanistic actions of co-repressor complexes | Q28640957 | ||
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress | Q29547441 | ||
CRM1 is responsible for intracellular transport mediated by the nuclear export signal | Q29547861 | ||
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action | Q29615696 | ||
A Drosophila model of Parkinson's disease | Q29617052 | ||
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence | Q29618819 | ||
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum | Q29620475 | ||
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans | Q30496743 | ||
A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. | Q33762395 | ||
The need for a simple animal model to understand sleep | Q33869429 | ||
Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder | Q33910429 | ||
The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis | Q34085639 | ||
The benzamide MS-275 is a potent, long-lasting brain region-selective inhibitor of histone deacetylases. | Q34334999 | ||
The remote roots of consciousness in fruit-fly selective attention? | Q34394981 | ||
Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site. | Q34407305 | ||
A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration | Q34562996 | ||
Post-translational modifications regulate the ticking of the circadian clock. | Q34605395 | ||
The cryptocephal gene (ATF4) encodes multiple basic-leucine zipper proteins controlling molting and metamorphosis in Drosophila. | Q34610035 | ||
Animal sleep: a review of sleep duration across phylogeny | Q34710797 | ||
Pharmacogenetic rescue in time and space of the rutabaga memory impairment by using Gene-Switch. | Q35122058 | ||
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice | Q36156959 | ||
Sleep disturbance in schizophrenia | Q36272532 | ||
Drosophila as a model for human neurodegenerative disease | Q36312196 | ||
Disrupted in schizophrenia 1: building brains and memories | Q36470351 | ||
A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions | Q36517223 | ||
Sleep disorders in psychiatry | Q36595659 | ||
Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death | Q36605673 | ||
Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses | Q36690868 | ||
Activating transcription factor 4 is translationally regulated by hypoxic stress | Q37349289 | ||
Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins | Q39391393 | ||
Analysis of heat-shock protein�70 gene polymorphisms and the risk of Parkinson?s disease | Q40618665 | ||
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease | Q43874109 | ||
Integration of long-term-memory-related synaptic plasticity involves bidirectional regulation of gene expression and chromatin structure | Q44220427 | ||
Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1). | Q44264433 | ||
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila | Q44662134 | ||
Essentials of sleep recordings in Drosophila: moving beyond sleep time. | Q45989237 | ||
Dopaminergic modulation of arousal in Drosophila | Q46179218 | ||
Drosophila melanogaster: an insect model for fundamental studies of sleep | Q46427470 | ||
A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis | Q47071522 | ||
Embryonic and larval development of the Drosophila mushroom bodies: concentric layer subdivisions and the role of fasciclin II. | Q47071896 | ||
Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria. | Q47715169 | ||
Uncoupling of brain activity from movement defines arousal States in Drosophila | Q48088457 | ||
Conserved cis-regulatory modules mediate complex neural expression patterns of the eyeless gene in the Drosophila brain | Q48168220 | ||
Behavioral phenotypes of Disc1 missense mutations in mice | Q48178658 | ||
Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300. | Q48196721 | ||
Primate disrupted-in-schizophrenia-1 (DISC1): high divergence of a gene for major mental illnesses in recent evolutionary history. | Q48423691 | ||
Electrophysiological correlates of rest and activity in Drosophila melanogaster | Q48441456 | ||
Sleep in Drosophila is regulated by adult mushroom bodies | Q48497891 | ||
A dynamic role for the mushroom bodies in promoting sleep in Drosophila | Q48497900 | ||
DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex | Q48516263 | ||
Correlates of sleep and waking in Drosophila melanogaster | Q48729010 | ||
Rest in Drosophila is a sleep-like state | Q48729018 | ||
Association of DISC1 with autism and Asperger syndrome | Q50313353 | ||
Human neurodegenerative disease modeling using Drosophila. | Q52605243 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | sleep | Q35831 |
P304 | page(s) | 1138-48, 1069 | |
P577 | publication date | 2008-09-02 | |
P1433 | published in | Molecular Psychiatry | Q6895973 |
P1476 | title | Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly. | |
P478 | volume | 13 |
Q33652520 | 708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits |
Q36894927 | A dynamic deep sleep stage in Drosophila |
Q47788104 | A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations |
Q36083129 | A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins |
Q42716547 | Abnormal wake/sleep pattern in a novel gain-of-function model of DISC1 |
Q37730673 | Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease |
Q48361051 | Altered subcellular distribution of the 75-kDa DISC1 isoform, cAMP accumulation, and decreased neuronal migration in schizophrenia and bipolar disorder: implications for neurodevelopment. |
Q47663423 | Basic Neuroscience Illuminates Causal Relationship Between Sleep and Memory: Translating to Schizophrenia |
Q37721142 | Big ideas for small brains: what can psychiatry learn from worms, flies, bees and fish? |
Q30465575 | Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility. |
Q37806285 | CREB: a multifaceted regulator of neuronal plasticity and protection |
Q36057664 | Calpain-mediated cleavage of DARPP-32 in Alzheimer's disease |
Q41290333 | Cell Type-Specific Effects of Mutant DISC1: A Proteomics Study |
Q35091791 | DISC1 (disrupted-in-schizophrenia-1) regulates differentiation of oligodendrocytes |
Q37998459 | DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders |
Q36282891 | DISC1 Protein Regulates γ-Aminobutyric Acid, Type A (GABAA) Receptor Trafficking and Inhibitory Synaptic Transmission in Cortical Neurons. |
Q33813559 | DISC1 and Huntington's disease--overlapping pathways of vulnerability to neurological disorder? |
Q37698116 | DISC1 as a therapeutic target for mental illnesses. |
Q41444596 | DISC1 causes associative memory and neurodevelopmental defects in fruit flies |
Q28299770 | DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking |
Q36634401 | DISC1 genetics, biology and psychiatric illness |
Q28572432 | DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth |
Q39378712 | DISC1 variants 37W and 607F disrupt its nuclear targeting and regulatory role in ATF4-mediated transcription |
Q37061724 | DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. |
Q28302106 | DISC1-binding proteins in neural development, signalling and schizophrenia |
Q28393891 | DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness |
Q26851318 | DISC1: a key lead in studying cortical development and associated brain disorders |
Q42801080 | Disrupted-in-Schizophrenia 1 (DISC1) is necessary for the correct migration of cortical interneurons. |
Q47732362 | Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways. |
Q92642814 | Dopamine D1 Receptor (D1R) Expression Is Controlled by a Transcriptional Repressor Complex Containing DISC1 |
Q47970219 | Drosophila Studies on Autism Spectrum Disorders |
Q38008577 | Evaluating the links between schizophrenia and sleep and circadian rhythm disruption |
Q37714970 | Gene models of schizophrenia: DISC1 mouse models |
Q37714952 | Genetic animal models for schizophrenia: advantages and limitations of genetic manipulation in drosophila, zebrafish, rodents, and primates |
Q42611080 | Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses |
Q33630685 | Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. |
Q91049140 | Host-parasite interaction associated with major mental illness |
Q34858502 | Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery |
Q36799041 | I Believe I Can Fly!: Use of Drosophila as a Model Organism in Neuropsychopharmacology Research. |
Q39227526 | Interaction of DISC1 with the PTB domain of Tensin2. |
Q34233683 | Linking neurodevelopmental and synaptic theories of mental illness through DISC1 |
Q58759716 | Matrin-3 is essential for fibroblast growth factor 2-dependent maintenance of neural stem cells |
Q90216168 | Mechanisms underlying the role of DISC1 in synaptic plasticity |
Q37055287 | Modeling cognitive endophenotypes of schizophrenia in mice |
Q37714980 | Modeling schizophrenia in flies |
Q38117145 | Modeling the genetic basis for human sleep disorders in Drosophila |
Q38310750 | Neural oscillations as a translational tool in schizophrenia research: rationale, paradigms and challenges |
Q38203026 | Neural oscillations during non-rapid eye movement sleep as biomarkers of circuit dysfunction in schizophrenia |
Q37588242 | Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1. |
Q47605519 | Overexpression of Truncated Human DISC1 Induces Appearance of Hindbrain Oligodendroglia in the Forebrain During Development |
Q42280876 | Regulation of N-methyl-D-aspartate receptors by disrupted-in-schizophrenia-1. |
Q37164610 | SUMOylation of DISC1: a potential role in neural progenitor proliferation in the developing cortex. |
Q52690506 | Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems. |
Q37772758 | Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease |
Q37426505 | Sleep and plasticity in schizophrenia |
Q92833427 | Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders |
Q39351825 | The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. |
Q57027971 | The TRAX, DISC1, and GSK3 complex in mental disorders and therapeutic interventions |
Q33915828 | The natural Disc1-deletion present in several inbred mouse strains does not affect sleep. |
Q39284469 | The neurophysics of psychiatric diagnosis: Clinical brain profiling |
Q38999268 | The role of endoplasmic reticulum stress in neurodegenerative disease |
Q36594911 | Transient activation of dopaminergic neurons during development modulates visual responsiveness, locomotion and brain activity in a dopamine ontogeny model of schizophrenia |
Q28261398 | Understanding the role of DISC1 in psychiatric disease and during normal development |
Q50418525 | Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism. |
Q37288077 | Who's in charge? Nuclear receptor coactivator and corepressor function in brain and behavior |
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