DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth

scientific journal article

DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MP.2010.60
P698PubMed publication ID20479754
P5875ResearchGate publication ID44608722

P50authorRyusuke KuwaharaQ57624141
P2093author name stringM Tohyama
A Ito
K Yamada
T Hattori
S Shimizu
T Katayama
Y Koyama
S Matsuzaki
N Kumamoto
P2860cites workN-cadherin and integrins: two receptor systems that mediate neuronal process outgrowth on astrocyte surfacesQ69854815
The participation of a putative cell surface receptor for laminin and fibronectin in peripheral neurite extensionQ69995008
DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutationQ24305439
DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1Q24306600
Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnessesQ24309410
DISC1 localizes to the centrosome by binding to kendrinQ24337243
Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowthQ24541302
Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expressionQ24562198
Common genetic variants on 5p14.1 associate with autism spectrum disordersQ24603204
Integrins: bidirectional, allosteric signaling machinesQ27860700
Yeast two-hybrid screens implicate DISC1 in brain development and functionQ28185066
Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowthQ28188775
Evolutionary constraints on the Disrupted in Schizophrenia locusQ28207935
Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disordersQ28245122
The DISC locus in psychiatric illnessQ28251868
Understanding the role of DISC1 in psychiatric disease and during normal developmentQ28261398
SchizophreniaQ28267772
DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signalingQ28282412
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brainQ28507787
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212Q28513802
A neuronal cell line (PC12) expresses two beta 1-class integrins-alpha 1 beta 1 and alpha 3 beta 1-that recognize different neurite outgrowth-promoting domains in lamininQ28565664
PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiationQ28568250
DISC1 regulates neurotrophin-induced axon elongation via interaction with Grb2Q28574208
DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1Q28576213
A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex developmentQ28582746
Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1Q28583457
Integrin requirement for hippocampal synaptic plasticity and spatial memoryQ28592878
Implications of normal brain development for the pathogenesis of schizophreniaQ29618740
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergenceQ29618819
Cadherin cell adhesion receptors as a morphogenetic regulatorQ29620503
Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficitsQ30475728
Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.Q30489568
A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.Q30830598
A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse.Q33762395
Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascadeQ33777725
Analysis of protocadherin alpha gene enhancer polymorphism in bipolar disorder and schizophrenia.Q33821683
Molecular modification of N-cadherin in response to synaptic activityQ33892687
Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorderQ33910429
Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia.Q33914120
Cadherins in embryonic and neural morphogenesisQ33938474
Catching up on schizophrenia: natural history and neurobiologyQ34122141
Modifier of cell adhesion regulates N-cadherin-mediated cell-cell adhesion and neurite outgrowth.Q34383996
A model for central synaptic junctional complex formation based on the differential adhesive specificities of the cadherinsQ34398309
Molecular brain imaging and the neurobiology and genetics of schizophreniaQ35608262
Cross-regulation of Wnt signaling and cell adhesionQ35956859
Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowthQ36217781
Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memoryQ36690923
Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches.Q36694659
Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illnessQ36933003
Extracellular matrix molecules and their receptors: functions in neural developmentQ37178903
Distinct roles of the beta 1-class integrins at the developing and the mature hippocampal excitatory synapseQ37218724
Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1.Q37588242
The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.Q39758028
The post-synaptic density: putative involvement in synapse stabilization via cadherins and covalent modification by ubiquitinationQ40530625
Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia.Q40810638
Cadherins in the developing central nervous system: an adhesive code for segmental and functional subdivisionsQ41256443
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.Q43271908
Localization and seizure-regulation of integrin beta 1 mRNA in adult rat brainQ43525447
Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortexQ43715204
Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1).Q44264433
N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neuritesQ44408459
Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memoryQ46113483
Immunohistochemical analysis of Disc1 expression in the developing and adult hippocampusQ46488452
Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS.Q47070236
Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria.Q47715169
The synaptic hypothesis of schizophrenia.Q48249154
N-cadherin redistribution during synaptogenesis in hippocampal neurons.Q48407647
Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signalingQ48426188
Developmental changes in integrin beta-subunits in rat cerebral cortex.Q48597094
Lamina-specific connectivity in the brain: regulation by N-cadherin, neurotrophins, and glycoconjugatesQ48704404
Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development.Q51040069
Morphologic fate of diencephalic prosomeres and their subdivisions revealed by mapping cadherin expression.Q52167816
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectcell adhesionQ187640
neuriteQ1534415
P304page(s)778, 798-809
P577publication date2010-05-18
P1433published inMolecular PsychiatryQ6895973
P1476titleDISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth
P478volume15

Reverse relations

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