Evolutionary constraints on the Disrupted in Schizophrenia locus

scientific article (publication date: 2003)

Evolutionary constraints on the Disrupted in Schizophrenia locus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0888-7543(02)00026-5
P698PubMed publication ID12573262
P5875ResearchGate publication ID10912869

P50authorMartin S. TaylorQ30503724
David J. PorteousQ37662552
P2093author name stringJ Kirsty Millar
Rebecca S Devon
P2860cites workC. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylationQ24291783
Isolation and characterization of a cDNA encoding a Translin-like protein, TRAXQ24317034
Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.Q24535773
Gapped BLAST and PSI-BLAST: a new generation of protein database search programsQ24545170
Using neural networks for prediction of the subcellular location of proteinsQ24547827
Base-calling of automated sequencer traces using phred. I. Accuracy assessmentQ27860665
Prediction of complete gene structures in human genomic DNAQ27860780
Disruption of two novel genes by a translocation co-segregating with schizophreniaQ28144559
Characterization and comparative analysis of the EGLN gene familyQ28189003
Chromosome 1 loci in Finnish schizophrenia familiesQ28208147
Association within a family of a balanced autosomal translocation with major mental illnessQ28257476
Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neuronsQ28569931
PipMaker--a web server for aligning two genomic DNA sequencesQ28776457
A molecular timescale for vertebrate evolutionQ29547791
Using CLUSTAL for multiple sequence alignmentsQ29547794
VISTA : visualizing global DNA sequence alignments of arbitrary lengthQ29614270
Finding nuclear localization signalsQ29614387
PHD: predicting one-dimensional protein structure by profile-based neural networksQ29614390
A computer program for aligning a cDNA sequence with a genomic DNA sequenceQ29618232
SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neuronsQ31520793
Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia.Q33914120
Identification of genes from a schizophrenia-linked translocation breakpoint regionQ33946639
The genetic epidemiology of schizophrenia and of schizophrenia spectrum disordersQ34128579
Nuts and bolts of psychiatric genetics: building on the Human Genome ProjectQ34133340
Evolutionary fates and origins of U12-type introns.Q34487062
Differences in HERV-K LTR insertions in orthologous loci of humans and great apesQ34508354
Computational comparison of human genomic sequence assemblies for a region of chromosome 4.Q35004232
Complete sequencing of the Fugu WAGR region from WT1 to PAX6: dramatic compaction and conservation of synteny with human chromosome 11p13.Q36636733
Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genomeQ36754912
Isolation and characterization of the mouse translin-associated protein X (Trax) geneQ38312693
Human-specific integrations of the HERV-K endogenous retrovirus familyQ39583010
Genomic sequence analysis of Fugu rubripes CFTR and flanking genes in a 60 kb region conserving synteny with 800 kb of human chromosome 7.Q40414290
Gain of Sp1 sites and loss of repressor sequences associated with a young, transcriptionally active subset of HERV-H endogenous long terminal repeatsQ41196068
Identification and Characterization of a Proteasome Subunit Cluster in the Japanese Pufferfish (Fugu rubripes)Q61761324
The molecular genetics of schizophreniaQ71691960
Mouse testis brain ribonucleic acid-binding protein/translin colocalizes with microtubules and is immunoprecipitated with messenger ribonucleic acids encoding myelin basic protein, alpha calmodulin kinase II, and protamines 1 and 2Q73469566
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectschizophreniaQ41112
P304page(s)67-77
P577publication date2003-01-01
P1433published inGenomicsQ5533503
P1476titleEvolutionary constraints on the Disrupted in Schizophrenia locus
P478volume81

Reverse relations

cites work (P2860)
Q33762395A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse.
Q28254976A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder
Q47788104A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations
Q35832061AKT/GSK3 signaling pathway and schizophrenia
Q38708466Adult Neurogenesis and Psychiatric Disorders
Q26781630Associating schizophrenia, long non-coding RNAs and neurostructural dynamics
Q43040891Association of Disrupted in Schizophrenia 1 (DISC1) missense variants with ultra-resistant schizophrenia
Q48909820Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse.
Q42681189Characterization of 43 non-protein-coding mRNA genes in Arabidopsis, including the MIR162a-derived transcripts.
Q28287390DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness
Q43015032DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan
Q36634401DISC1 genetics, biology and psychiatric illness
Q48516263DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex
Q28572432DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth
Q24643052DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms
Q24306600DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1
Q28393891DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness
Q50749733Disc1 deletion is present in Swiss-derived inbred mouse strains: implications for transgenic studies of learning and memory.
Q30488747Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation
Q33910429Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder
Q64018589Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice
Q46970805Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs
Q24635628Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia
Q35875178Genetics of schizophrenia and bipolar affective disorder: strategies to identify candidate genes.
Q36021547Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate
Q51738410Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.
Q34233683Linking neurodevelopmental and synaptic theories of mental illness through DISC1
Q36823293Long noncoding RNAs in psychiatric disorders
Q59096304Neutral evolution of ‘non-coding’ complementary DNAs (reply)
Q26851626Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease
Q30489568Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.
Q47342098Replication of 1q42 linkage in Finnish schizophrenia pedigrees
Q46117859Survey of schizophrenia and bipolar disorder candidate genes using chromatin immunoprecipitation and tiled microarrays (ChIP-chip).
Q28251868The DISC locus in psychiatric illness
Q57027971The TRAX, DISC1, and GSK3 complex in mental disorders and therapeutic interventions
Q52567245The complex history of distal human chromosome 1q.
Q33842912Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

Search more.