DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking

scientific article

DISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/HMG/DDT485
P3181OpenCitations bibliographic resource ID285371
P932PMC publication ID3900104
P698PubMed publication ID24092329
P5875ResearchGate publication ID257350346

P50authorDinesh C. SoaresQ37375711
P2093author name stringDavid J Porteous
Fumiaki Ogawa
J Kirsty Millar
Shaun Mackie
Elise L V Malavasi
Darragh K Crummie
Jennifer E Eykelenboom
P2860cites workPINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motilityQ24296955
Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with MitofilinQ24301405
Regulation of mitochondrial dynamics and neurodegenerative diseases.Q37845646
What genetics tells us about the causes and mechanisms of Parkinson's diseaseQ37947563
DISC1 variants 37W and 607F disrupt its nuclear targeting and regulatory role in ATF4-mediated transcriptionQ39378712
Serotonin stimulates mitochondrial transport in hippocampal neuronsQ40074582
Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.Q41859552
Identification of high risk DISC1 structural variants with a 2% attributable risk for schizophreniaQ47569502
Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria.Q47715169
A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization.Q47717695
Disrupted in Schizophrenia-1 regulates intracellular trafficking of mitochondria in neurons.Q52605145
Human Miltons associate with mitochondria and induce microtubule-dependent remodeling of mitochondrial networksQ57274175
Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophreniaQ24306904
The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motilityQ24315540
Hypertonia-associated protein Trak1 is a novel regulator of endosome-to-lysosome traffickingQ24319839
GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesinQ24337834
Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.Q24535773
Dopamine inhibits mitochondrial motility in hippocampal neuronsQ27300818
Disruption of two novel genes by a translocation co-segregating with schizophreniaQ28144559
DISC1 at 10: connecting psychiatric genetics and neuroscienceQ28250914
The DISC locus in psychiatric illnessQ28251868
Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondriaQ28259578
DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signalingQ28282412
DISC1: Structure, Function, and Therapeutic Potential for Major Mental IllnessQ28393891
Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic miceQ28509817
GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neuronsQ28568628
DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1Q28576213
DISC1, PDE4B, and NDE1 at the centrosome and synapseQ28585118
Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.Q30489568
Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neuronsQ30500228
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traitsQ33652520
Linking neurodevelopmental and synaptic theories of mental illness through DISC1Q34233683
A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3.Q34461951
Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.Q34804839
Regulation of axonal mitochondrial transport and its impact on synaptic transmissionQ34917230
DISC1 regulates synaptic vesicle transport via a lithium-sensitive pathwayQ35164530
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteinsQ36083129
Visualization and quantification of mitochondrial dynamics in living animal cells.Q36796290
Constellation of HCN channels and cAMP regulating proteins in dendritic spines of the primate prefrontal cortex: potential substrate for working memory deficits in schizophreniaQ36904298
Mitochondria on the moveQ36931216
Moving mitochondria: establishing distribution of an essential organelleQ36974920
The Miro GTPases: at the heart of the mitochondrial transport machineryQ37450067
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
P304page(s)906-19
P577publication date2014-02-15
P1433published inHuman Molecular GeneticsQ2720965
P1476titleDISC1 complexes with TRAK1 and Miro1 to modulate anterograde axonal mitochondrial trafficking
P478volume23

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cites work (P2860)
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Q43015032DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan
Q52671081DISC1 is a coordinator of intracellular trafficking to shape neuronal development and connectivity.
Q58761899DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness
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