Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function

scientific article published on 09 January 2014

Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YJMCC.2013.12.029
P932PMC publication ID3995348
P698PubMed publication ID24412531

P50authorAnisha A. GupteQ39829946
Keith A YoukerQ51717527
Dale J. HamiltonQ61785100
Guillermo Torre-AmioneQ99344173
Matthias LoebeQ114312358
P2093author name stringWilla A Hsueh
Heinrich Taegtmeyer
Andrea M Cordero-Reyes
P2860cites workIncreased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heartQ28570211
The failing heart--an engine out of fuelQ29617881
Substrate-specific derangements in mitochondrial metabolism and redox balance in the atrium of the type 2 diabetic human heartQ33566045
Defective DNA replication impairs mitochondrial biogenesis in human failing heartsQ33892073
Biochemical studies of energy production in the failing human heartQ34080123
Interaction of TNF with angiotensin II contributes to mitochondrial oxidative stress and cardiac damage in ratsQ34441654
Impaired mitochondrial biogenesis precedes heart failure in right ventricular hypertrophy in congenital heart diseaseQ35556097
Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylationQ36870637
Mitochondria in cardiac hypertrophy and heart failureQ37246892
Modulation of mitochondrial bioenergetics in the isolated Guinea pig beating heart by potassium and lidocaine cardioplegia: implications for cardioprotection.Q37415419
Mitochondria in the human heartQ37437393
Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesityQ38319554
Abnormal biochemistry in myocardial failureQ39898667
Quantification of the contribution of various steps to the control of mitochondrial respiration.Q41619983
Transgenic mouse model with deficient mitochondrial polymerase exhibits reduced state IV respiration and enhanced cardiac fibrosisQ41940970
Abnormal mitochondrial respiration in failed human myocardiumQ42497033
Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overloadQ43207763
Metabolic gene expression in fetal and failing human heartQ43819742
Energy status of the rapidly paced canine myocardium in congestive heart failureQ43841823
Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathyQ44203656
Dysfunction of mitochondrial respiratory chain complex I in human failing myocardium is not due to disturbed mitochondrial gene expressionQ44264771
Alterations of the mitochondrial respiratory chain in human dilated cardiomyopathyQ44693079
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failureQ44842105
Mitochondrial tissue specificity of substrates utilization in rat cardiac and skeletal muscles.Q45134661
Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genesQ46098709
Is the failing heart out of fuel or a worn engine running rich? A study of mitochondria in old spontaneously hypertensive ratsQ46532282
Pressure overload differentially affects respiratory capacity in interfibrillar and subsarcolemmal mitochondriaQ48559552
Differential changes in respiratory capacity and ischemia tolerance of isolated mitochondria from atrophied and hypertrophied hearts.Q54592330
Respiratory enzymes in oxidative phosphorylation. III. The steady state.Q55037006
Mitochondrial function in heart muscle from patients with idiopathic dilated cardiomyopathyQ57631631
ACC/AHA Guidelines for the Evaluation and Management of Chronic Heart Failure in the Adult: Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1995 GuQ58975447
Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblastsQ60056610
Decreased mitochondrial oxidative phosphorylation capacity in the human heart with left ventricular systolic dysfunctionQ61918740
Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscleQ67715072
Some biochemical studies on subcellular systems isolated from fresh recipient human cardiac tissue obtained during transplantationQ68467960
Mitochondrial respiratory chain activity in idiopathic dilated cardiomyopathyQ73622527
Myocardial ischemia decreases oxidative phosphorylation through cytochrome oxidase in subsarcolemmal mitochondriaQ73757751
Improvement of myocardial mitochondrial function after hemodynamic support with left ventricular assist devices in patients with heart failureQ77072342
Energetics and function of the failing human heart with dilated or hypertrophic cardiomyopathyQ77829273
2009 Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines DeveQ83631957
Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heartQ84838077
Research advances in heart failure: a compendiumQ87150620
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
P304page(s)98-105
P577publication date2014-01-09
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleFreshly isolated mitochondria from failing human hearts exhibit preserved respiratory function
P478volume68

Reverse relations

cites work (P2860)
Q35235782A PKM2 signature in the failing heart.
Q40679405Assessment of Mitochondrial Dysfunction and Monoamine Oxidase Contribution to Oxidative Stress in Human Diabetic Hearts
Q52575994Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond.
Q49022015Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure
Q90349841Effective Metabolic Approaches for the Energy Starved Failing Heart: Bioenergetic Resiliency via Redundancy or Something Else?
Q37263909Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high-fat-fed ovariectomized mice.
Q33651722Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning
Q47381689Heart failure-induced activation of phospholipase iPLA2γ generates hydroxyeicosatetraenoic acids opening the mitochondrial permeability transition pore
Q64244369High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure
Q38974621How cardiomyocytes sense pathophysiological stresses for cardiac remodeling.
Q51531441Hypertrophy induced KIF5B controls mitochondrial localization and function in neonatal rat cardiomyocytes.
Q51763166Improved Cardiovascular Function in Old Mice after N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors.
Q54210821Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections.
Q89180768Metabolic Coordination of Physiological and Pathological Cardiac Remodeling
Q39245449Metabolic Recovery of the Failing Heart: Emerging Therapeutic Options.
Q27312512Metabolic remodeling in moderate synchronous versus dyssynchronous pacing-induced heart failure: integrated metabolomics and proteomics study
Q39395331Metabolic remodelling in hypertrophied and failing myocardium: a review.
Q39334518Mitochondrial Bioenergetics and Dysfunction in Failing Heart
Q88169588Mitochondrial Function in Non-ischemic Heart Failure
Q38759545Mitochondrial Therapies in Heart Failure
Q42053286Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts
Q28395925Monoamine Oxidases as Potential Contributors to Oxidative Stress in Diabetes: Time for a Study in Patients Undergoing Heart Surgery
Q38864091Myocardial recovery with mechanical circulatory support
Q37743798Pet Imaging and its Application in Cardiovascular Diseases
Q52624291Polymer Functionalization of Isolated Mitochondria for Cellular Transplantation and Metabolic Phenotype Alteration.
Q28387956Probing cytochrome c in living mitochondria with surface-enhanced Raman spectroscopy
Q38265521Rethinking cardiac metabolism: metabolic cycles to refuel and rebuild the failing heart
Q37139657Selective downregulation of mitochondrial electron transport chain activity and increased oxidative stress in human atrial fibrillation.
Q54481620Simultaneous exposure to nitric oxide inhibition and angiotensin II overload: is it a murine model of mitochondrial dysfunction in nonischemic heart failure?

Search more.