Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer

scientific article published on 29 March 2017

Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1084251902
P356DOI10.1186/S13045-017-0445-8
P932PMC publication ID5372308
P698PubMed publication ID28356122

P50authorMin SunQ91940108
P2093author name stringQing Liu
Chen Wei
Liang Zheng
Yuanyuan Chen
Min Sun
Fangfang Chen
Shuyi Wang
Chunxiao Zhang
Haibin Song
Chaogang Yang
Dongdong Shi
Zhenxian Xiang
P2860cites workmiR-195 and miR-483-5p Identified as Predictors of Poor Prognosis in Adrenocortical CancerQ45119395
Hippo/YAP, β-catenin, and the cancer cell: a "ménage à trois" in hepatoblastomaQ46397118
A meta-analysis of gene expression-based biomarkers predicting outcome after tamoxifen treatment in breast cancerQ46799300
MicroRNA-195 inhibits non-small cell lung cancer cell proliferation, migration and invasion by targeting MYB.Q51116914
MicroRNA-195 inhibits proliferation of cervical cancer cells by targeting cyclin D1a.Q52906148
Increased TEAD4 expression and nuclear localization in colorectal cancer promote epithelial-mesenchymal transition and metastasis in a YAP-independent manner.Q55042519
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
The Hippo pathway in colorectal cancerQ28082847
Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancerQ28086905
Cancer statistics, 2016Q29547383
Key issues in conducting a meta-analysis of gene expression microarray datasetsQ33366123
BRB-ArrayTools Data Archive for human cancer gene expression: a unique and efficient data sharing resourceQ33414654
Biomarker detection in the integration of multiple multi-class genomic studiesQ33627563
Polymorphisms in microRNA target sites modulate risk of lymphoblastic and myeloid leukemias and affect microRNA bindingQ33764157
microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathwayQ33792672
Expression of hippo pathway in colorectal cancerQ33796051
miRBase Tracker: keeping track of microRNA annotation changes.Q34080546
A Protective Role by Interleukin-17F in Colon TumorigenesisQ34235509
Colorectal cancer statistics, 2014.Q34660408
Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer CellsQ34770004
Diagnostic and prognostic microRNAs in stage II colon cancer.Q34803800
microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma.Q35684366
Estrogen regulates Hippo signaling via GPER in breast cancerQ35720044
Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stabilityQ35740352
Circulating miRNAs is a potential marker for gefitinib sensitivity and correlation with EGFR mutational status in human lung cancers.Q35835222
Comprehensive literature review and statistical considerations for microarray meta-analysisQ35955982
The emerging roles of YAP and TAZ in cancerQ36035567
miR-195 is a key regulator of Raf1 in thyroid cancerQ36208479
miR-195 Inhibits Tumor Progression by Targeting RPS6KB1 in Human Prostate CancerQ36244787
The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progressionQ36278724
An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detectionQ36294024
Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF.Q36297343
Hepatocellular carcinoma associated microRNA expression signature: integrated bioinformatics analysis, experimental validation and clinical significance.Q36413124
MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2.Q36433424
Wnt activated β-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cellsQ36544177
Clinical value of integrated-signature miRNAs in colorectal cancer: miRNA expression profiling analysis and experimental validationQ36545805
Colorectal cancer characterization and therapeutic target prediction based on microRNA expression profileQ36555317
MicroRNA profiles in colorectal carcinomas, adenomas and normal colonic mucosa: variations in miRNA expression and disease progressionQ36615420
Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistanceQ36923438
Meta-analysis of colorectal cancer gene expression profiling studies identifies consistently reported candidate biomarkersQ37113145
miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer.Q37295543
MicroRNA-195-5p is a potential diagnostic and therapeutic target for breast cancerQ37588827
Antitumor activity of miR-34a in peritoneal mesothelioma relies on c-MET and AXL inhibition: persistent activation of ERK and AKT signaling as a possible cytoprotective mechanismQ37591581
Integration of intercellular signaling through the Hippo pathwayQ38007284
MicroRNA-binding site polymorphisms in hematological malignancies.Q38271148
MicroRNA and targeted mRNA expression profiling analysis in human colorectal adenomas and adenocarcinomasQ38301716
Control of Proliferation and Cancer Growth by the Hippo Signaling PathwayQ38514410
Molecular biomarkers in gastric cancer.Q38519985
YAP and TAZ Take Center Stage in CancerQ38606718
Eribulin upregulates miR-195 expression and downregulates Wnt3a expression in non-basal-like type of triple-negative breast cancer cell MDA-MB-231.Q38819255
MicroRNA-195-5p, a new regulator of Fra-1, suppresses the migration and invasion of prostate cancer cellsQ38838196
EMT: 2016.Q38883448
The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal CancerQ38903548
Mutual inhibition between YAP and SRSF1 maintains long non-coding RNA, Malat1-induced tumourigenesis in liver cancerQ39030071
Mutual interaction between YAP and c-Myc is critical for carcinogenesis in liver cancerQ39101905
Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat modelQ45039242
P4510describes a project that useslimmaQ112236343
P433issue1
P921main subjectcolorectal cancerQ188874
microRNAQ310899
P304page(s)79
P577publication date2017-03-29
P1433published inJournal of Hematology & OncologyQ15724593
P1476titleIntegrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer
P478volume10

Reverse relations

cites work (P2860)
Q59794098CircFAT1 sponges miR-375 to promote the expression of Yes-associated protein 1 in osteosarcoma cells
Q58736691Circular RNA: new star, new hope in cancer
Q90153969Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways
Q59806405Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer
Q90363489Gene Expression Alterations and Molecular Analysis of CHEK1 in Solid Tumors
Q58780656Identification and Interaction Analysis of Molecular Markers in Colorectal Cancer by Integrated Bioinformatics Analysis
Q58122535Identification of Candidate Biomarkers Correlated With the Pathogenesis and Prognosis of Non-small Cell Lung Cancer via Integrated Bioinformatics Analysis
Q94463937Identification of Hub Genes Related to Carcinogenesis and Prognosis in Colorectal Cancer Based on Integrated Bioinformatics
Q90675894Identification of Potential Key Genes Associated With the Pathogenesis and Prognosis of Gastric Cancer Based on Integrated Bioinformatics Analysis
Q89147806Identifying autophagy gene-associated module biomarkers through construction and analysis of an autophagy-mediated ceRNA‑ceRNA interaction network in colorectal cancer
Q91712290Integrated Analysis Identifies a Nine-microRNA Signature Biomarker for Diagnosis and Prognosis in Colorectal Cancer
Q92361660Integrative Gene Expression Profiling Analysis to Investigate Potential Prognostic Biomarkers for Colorectal Cancer
Q90390289Integrative analysis reveals CRHBP inhibits renal cell carcinoma progression by regulating inflammation and apoptosis
Q97067035Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies
Q92366663Long non‑coding RNA LINC00473/miR‑195‑5p promotes glioma progression via YAP1‑TEAD1‑Hippo signaling
Q54122877MiR-126 functions as a tumor suppressor by targeting SRPK1 in human gastric cancer
Q47134775MiR-195 suppresses the metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by inhibiting YAP.
Q89883711MiR-195-5p Inhibits Malignant Progression of Cervical Cancer by Targeting YAP1
Q55027570MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells.
Q58547821MicroRNA-195: a review of its role in cancers
Q64235853MicroRNA-related transcription factor regulatory networks in human colorectal cancer
Q55509409MicroRNA‑195 inhibits cell proliferation, migration and invasion by targeting defective in cullin neddylation 1 domain containing 1 in cervical cancer.
Q61798124Msx1 loss suppresses formation of the ectopic crypts developed in the Apc-deficient small intestinal epithelium
Q49571165Overexpression of lncRNA ANRIL promoted the proliferation and migration of prostate cancer cells via regulating let-7a/TGF-β1/ Smad signaling pathway
Q55307845Prognostic value of microRNAs in colorectal cancer: a meta-analysis.
Q103759593Regulation of Hippo signaling pathway in cancer: A MicroRNA perspective
Q60917456The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negative breast cancer progression through regulating CCNE1 expression
Q92886973Tumor suppressive effects of the pleiotropically acting miR-195 in colorectal cancer cells
Q64228191Upregulation of STC2 in colorectal cancer and its clinicopathological significance
Q90370797YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer
Q89924216m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2-mediated YAP activity in NSCLC
Q42368955miR-125b-5p functions as a tumor suppressor gene partially by regulating HMGA2 in esophageal squamous cell carcinoma.
Q61797342miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC
Q92617046miR-195 inhibits esophageal cancer cell proliferation and promotes apoptosis by downregulating YAP1
Q64101718miR-195-5p/NOTCH2-mediated EMT modulates IL-4 secretion in colorectal cancer to affect M2-like TAM polarization

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