Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability

scientific article published on 26 May 2015

Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2015PNAS..112.7255Q
P356DOI10.1073/PNAS.1505917112
P932PMC publication ID4466726
P698PubMed publication ID26039999
P5875ResearchGate publication ID277781739

P2093author name stringDean Y Li
Hongbo R Luo
Keqiang Ye
Kun-Liang Guan
Qi Qi
P2860cites workA coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)Q24293710
Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5BQ24311684
The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinaseQ24318638
The Hippo Signaling Pathway in Development and CancerQ24603986
Hippo pathway-independent restriction of TAZ and YAP by angiomotinQ24614424
Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignanciesQ24647958
Expression of Yes-associated protein in common solid tumorsQ24657592
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 ampliconQ24682018
PP1 and PP2A phosphatases--cooperating partners in modulating retinoblastoma protein activationQ26991427
The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injuryQ27305276
The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysisQ28116063
Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasisQ28291163
YAP1 increases organ size and expands undifferentiated progenitor cellsQ28592519
Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.Q33819083
Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.Q33949395
PP1A-mediated dephosphorylation positively regulates YAP2 activityQ34016621
Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activationQ34126386
Netrins: versatile extracellular cues with diverse functionsQ34184016
Tumor Suppressor Ras Association Domain Family 5 (RASSF5/NORE1) Mediates Death Receptor Ligand-induced ApoptosisQ34251431
The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.Q34332258
Netrin-1 controls colorectal tumorigenesis by regulating apoptosisQ34345335
Akt-phosphorylated PIKE-A inhibits UNC5B-induced apoptosis in cancer cell lines in a p53-dependent mannerQ35011241
ASPP2 links the apical lateral polarity complex to the regulation of YAP activity in epithelial cellsQ35382323
Protein phosphatase 1 regulatory subunit 12A and catalytic subunit δ, new members in the phosphatidylinositide 3 kinase insulin-signaling pathwayQ35653805
The Hippo-YAP pathway: new connections between regulation of organ size and cancerQ35811415
The role of LPA and YAP signaling in long-term migration of human ovarian cancer cellsQ36847992
Rassf family of tumor suppressor polypeptides.Q37353443
Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppressionQ37410567
Netrin-1 and its dependence receptors as original targets for cancer therapyQ37637868
Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cellsQ39751251
Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1Q79929599
P433issue23
P407language of work or nameEnglishQ1860
P304page(s)7255-7260
P577publication date2015-05-26
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleNetrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability
P478volume112

Reverse relations

cites work (P2860)
Q64897062A network map of netrin receptor UNC5B-mediated signaling.
Q46062152An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
Q38732929Expression of netrin-1 by hypoxia contributes to the invasion and migration of prostate carcinoma cells by regulating YAP activity
Q37141368Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference.
Q37728657Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer
Q38630257Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation
Q64099741LKB1 and YAP phosphorylation play important roles in Celastrol-induced β-catenin degradation in colorectal cancer
Q46196382Making Connections: Guidance Cues and Receptors at Nonneural Cell-Cell Junctions
Q28817567Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion
Q36932907Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex.
Q46673544Neogenin-YAP signaling in neocortical astrocytic differentiation
Q33905507Netrin-1 promotes glioma growth by activating NF-κB via UNC5A
Q48502109Targeting Netrin-1 in glioblastoma stem-like cells inhibits growth, invasion, and angiogenesis.
Q97540643Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding motif (TAZ): a nexus between hypoxia and cancer

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