scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1019374389 |
P356 | DOI | 10.1038/NATURE02788 |
P698 | PubMed publication ID | 15343335 |
P50 | author | Jean-Yves Scoazec | Q43376228 |
Patrick Mehlen | Q61794296 | ||
Laetitia Mazelin | Q84891671 | ||
Christian Gespach | Q107569704 | ||
Agnès Bernet | Q27955850 | ||
P2093 | author name string | Dale E Bredesen | |
Christelle Bonod-Bidaud | |||
Laurent Pays | |||
Ségolène Arnaud | |||
P2860 | cites work | The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis | Q28116063 |
Lessons from hereditary colorectal cancer | Q28131788 | ||
p53RDL1 regulates p53-dependent apoptosis | Q28211258 | ||
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene | Q28236533 | ||
The dependence receptor hypothesis | Q28240263 | ||
Identification of a chromosome 18q gene that is altered in colorectal cancers | Q28274172 | ||
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system | Q29616040 | ||
p75NTR and the concept of cellular dependence: seeing how the other half die. | Q33592268 | ||
Netrin-1 acts as a survival factor via its receptors UNC5H and DCC. | Q33949395 | ||
Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation | Q34126386 | ||
Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog | Q34220947 | ||
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins | Q36294082 | ||
Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice | Q38346730 | ||
Induction of apoptosis by the low-affinity NGF receptor | Q41541620 | ||
The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease | Q22254713 | ||
Deleted in Colorectal Cancer (DCC) encodes a netrin receptor | Q24313278 | ||
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors | Q24564011 | ||
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment | Q24683182 | ||
A genetic model for colorectal tumorigenesis | Q27860582 | ||
P433 | issue | 7004 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | apoptotic process | Q14599311 |
P304 | page(s) | 80-84 | |
P577 | publication date | 2004-09-01 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | Netrin-1 controls colorectal tumorigenesis by regulating apoptosis | |
P478 | volume | 431 |
Q38357627 | A ChIP-chip approach reveals a novel role for transcription factor IRF1 in the DNA damage response |
Q28943411 | A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population |
Q37635945 | APC and its modifiers in colon cancer. |
Q51799719 | Aberrant methylation of the netrin-1 receptor genes UNC5C and DCC detected in advanced colorectal cancer. |
Q35011241 | Akt-phosphorylated PIKE-A inhibits UNC5B-induced apoptosis in cancer cell lines in a p53-dependent manner |
Q36216011 | Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowth |
Q27009170 | Animal models of colorectal cancer |
Q28744477 | Autocrine netrin function inhibits glioma cell motility and promotes focal adhesion formation |
Q89722177 | Blocking SHH/Patched interaction triggers tumor growth inhibition through Patched-induced apoptosis |
Q53365421 | Cancer: cell survival guide. |
Q35031300 | Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO. |
Q53605307 | Characterization of epithelial cell shedding from human small intestine. |
Q48085691 | Cloning of vertebrate Protogenin (Prtg) and comparative expression analysis during axis elongation |
Q30551486 | Colon Macrophages Polarized by Commensal Bacteria Cause Colitis and Cancer through the Bystander Effect |
Q37557198 | Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death |
Q49830500 | Common Deregulation of Seven Biological Processes by MicroRNAs in Gastrointestinal Cancers |
Q36637287 | Context is everything for dependence receptors in colorectal cancer |
Q89855372 | Control of cell death/survival balance by the MET dependence receptor |
Q37769045 | Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis |
Q30435788 | Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. |
Q59058784 | DCC constrains tumour progression via its dependence receptor activity |
Q34311583 | Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria. |
Q34641317 | Deleted in Colorectal Cancer (DCC) pathfinding: axon guidance gene finally turned tumor suppressor |
Q39391784 | Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours |
Q35638934 | Deletion of UNC5B in Kidney Epithelium Exacerbates Diabetic Nephropathy in Mice |
Q38243917 | Dependence receptors and colorectal cancer. |
Q37696275 | Dependence receptors: a new paradigm in cell signaling and cancer therapy |
Q39937068 | Dichotomous metabolism of Enterococcus faecalis induced by haematin starvation modulates colonic gene expression |
Q47887398 | Distinct functions for netrin 1 in chicken and murine semicircular canal morphogenesis |
Q34292791 | Down-regulation of neogenin accelerated glioma progression through promoter Methylation and its overexpression in SHG-44 Induced Apoptosis |
Q28507499 | Ephrin signalling controls brain size by regulating apoptosis of neural progenitors |
Q33618844 | Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4 |
Q39926049 | EphrinB3 is an anti-apoptotic ligand that inhibits the dependence receptor functions of EphA4 receptors during adult neurogenesis. |
Q34069798 | Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. |
Q24645421 | FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5 |
Q51395347 | Gene expression of the repulsive guidance molecules during development of the mouse intestine. |
Q35881121 | Genetic and epigenetic alterations of netrin-1 receptors in gastric cancer with chromosomal instability |
Q37362753 | Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study |
Q44948557 | Hepatitis C, EGFR, cirrhosis and netrin-1: potential implications for HCC onset |
Q36896177 | High levels of cleaved caspase-3 in colorectal tumour stroma predict good survival |
Q37222761 | Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: mechanism for macrophage retention and survival |
Q42095470 | Identification of new netrin family members in zebrafish: developmental expression of netrin 2 and netrin 4. |
Q24647958 | Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies |
Q36149589 | Integrins as a distinct subtype of dependence receptors |
Q39884897 | Interference with netrin-1 and tumor cell death in non-small cell lung cancer |
Q33739093 | Interfering with multimerization of netrin-1 receptors triggers tumor cell death. |
Q39264836 | Kidney proximal tubular epithelial-specific overexpression of netrin-1 suppresses inflammation and albuminuria through suppression of COX-2-mediated PGE2 production in streptozotocin-induced diabetic mice |
Q39967986 | Lipid raft localization and palmitoylation: identification of two requirements for cell death induction by the tumor suppressors UNC5H. |
Q36545296 | MUC4-promoted neural invasion is mediated by the axon guidance factor Netrin-1 in PDAC |
Q28242176 | Metastasis: a question of life or death |
Q44931586 | Molecular guidance cues necessary for axon pathfinding from the ventral cochlear nucleus |
Q36558037 | Multifunctional protein APPL2 contributes to survival of human glioma cells. |
Q63915825 | Netrin Family: Role for Protein Isoforms in Cancer |
Q82133954 | Netrin PIPes up |
Q47374262 | Netrin-1 Prevents Rat Primary Cortical Neurons from Apoptosis via the DCC/ERK Pathway |
Q24645254 | Netrin-1 acts as a survival factor for aggressive neuroblastoma |
Q28295909 | Netrin-1 and its receptors in tumorigenesis |
Q46782195 | Netrin-1 and kidney injury. II. Netrin-1 is an early biomarker of acute kidney injury. |
Q38171332 | Netrin-1 as a potential target for metastatic cancer: focus on colorectal cancer |
Q35740352 | Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability |
Q24657804 | Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer |
Q35125199 | Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases |
Q41847756 | Netrin-1 guides inflammatory cell migration to control mucosal immune responses during intestinal inflammation |
Q87126886 | Netrin-1 induces epithelial-mesenchymal transition and promotes hepatocellular carcinoma invasiveness |
Q39894506 | Netrin-1 interacts with amyloid precursor protein and regulates amyloid-beta production |
Q46277359 | Netrin-1 is a novel regulator of vascular endothelial function in diabetes |
Q36936345 | Netrin-1 is a survival factor during commissural neuron navigation |
Q28506848 | Netrin-1 is required for the normal development of spinal cord oligodendrocytes |
Q42260805 | Netrin-1 overexpression in kidney proximal tubular epithelium ameliorates cisplatin nephrotoxicity. |
Q42458873 | Netrin-1 overexpression protects kidney from ischemia reperfusion injury by suppressing apoptosis. |
Q35757999 | Netrin-1 promotes cell migration and invasion by down-regulation of BVES expression in human hepatocellular carcinoma. |
Q91756559 | Netrin-1 promotes cell neural invasion in gastric cancer via its receptor neogenin |
Q89849545 | Netrin-1 promotes epithelium repair in corneal injury |
Q41612676 | Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway |
Q33905507 | Netrin-1 promotes glioma growth by activating NF-κB via UNC5A |
Q34010358 | Netrin-1 promotes medulloblastoma cell invasiveness and angiogenesis, and demonstrates elevated expression in tumor tissue and urine of patients with pediatric medulloblastoma |
Q36836239 | Netrin-1 regulates colon-kidney cross talk through suppression of IL-6 function in a mouse model of DSS-colitis |
Q35877709 | Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance |
Q37269416 | Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer |
Q37386029 | Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression |
Q35833147 | Netrin-4 as a biomarker promotes cell proliferation and invasion in gastric cancer. |
Q46085414 | Netrin-4 regulates angiogenic responses and tumor cell growth |
Q42448747 | Netrin-dependent downregulation of Frazzled/DCC is required for the dissociation of the peripodial epithelium in Drosophila. |
Q54586880 | Netrin/DCC-mediated attraction of vagal sensory axons to the fetal mouse gut. |
Q36759032 | Netrins: beyond the brain |
Q35878812 | Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis |
Q24642741 | Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis |
Q37998778 | Neurotrophins and cell death. |
Q37843457 | Novel roles for Slits and netrins: axon guidance cues as anticancer targets? |
Q35970441 | O-GlcNAc modification of transcription factor Sp1 mediates hyperglycemia-induced VEGF-A upregulation in retinal cells |
Q28291163 | Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis |
Q53561253 | PIN1, the cell cycle and cancer. |
Q33787970 | Paracrine signalling loops in adult human and mouse pancreatic islets: netrins modulate beta cell apoptosis signalling via dependence receptors |
Q36285896 | Phenotypic analysis of mice completely lacking netrin 1. |
Q33756078 | Protogenin, a new member of the immunoglobulin superfamily, is implicated in the development of the mouse lower first molar |
Q36764217 | Proximal tubule-specific overexpression of netrin-1 suppresses acute kidney injury-induced interstitial fibrosis and glomerulosclerosis through suppression of IL-6/STAT3 signaling |
Q34364284 | Putative miRNAs for the diagnosis of dyslexia, dyspraxia, and specific language impairment. |
Q60931600 | RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer |
Q36193418 | Receptors that mediate cellular dependence |
Q38042589 | Revisiting the nucleolus: from marker to dynamic integrator of cancer signaling |
Q89874235 | Revisiting the role of Dcc in visual system development with a novel eye clearing method |
Q38066229 | Role of Netrin-1 Beyond the Brain: From Biomarker of Tissue Injury to Therapy for Inflammatory Diseases |
Q45353589 | Role of genetic variants of deleted in colorectal carcinoma (DCC) polymorphisms and esophageal and gastric cancers risk in Kashmir Valley and meta-analysis |
Q36163579 | Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers |
Q36555506 | Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis |
Q26771240 | Studies of Tumor Suppressor Genes via Chromosome Engineering |
Q36323041 | TNF-α mediates macrophage-induced bystander effects through Netrin-1. |
Q48502109 | Targeting Netrin-1 in glioblastoma stem-like cells inhibits growth, invasion, and angiogenesis. |
Q36525869 | Targeting netrin-1/DCC interaction in diffuse large B-cell and mantle cell lymphomas |
Q34755871 | Targeting the PI3K/mTOR pathway in murine endocrine cell lines: in vitro and in vivo effects on tumor cell growth |
Q36564975 | Targeting the epidermal growth factor receptor in the treatment of colorectal cancer: state of the art. |
Q33932269 | The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor |
Q34661111 | The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm. |
Q36193422 | The brain within the tumor: new roles for axon guidance molecules in cancers. |
Q33358945 | The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue. |
Q24545021 | The dependence receptor DCC requires lipid raft localization for cell death signaling |
Q35752727 | The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth. |
Q24318638 | The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase |
Q80368731 | The dependence receptor notion: another way to see death |
Q91526734 | The functional variant of NTN1 contributes to the risk of nonsyndromic cleft lip with or without cleft palate |
Q37172151 | The genomics of colorectal cancer: state of the art. |
Q33327050 | The neogenin intracellular domain regulates gene transcription via nuclear translocation |
Q54977478 | The role of netrin-1 in metastatic renal cell carcinoma treated with sunitinib. |
Q35360743 | Tumor suppressive activity of prolyl isomerase Pin1 in renal cell carcinoma. |
Q33983402 | UNC5B receptor deletion exacerbates DSS-induced colitis in mice by increasing epithelial cell apoptosis |
Q59133663 | Ultrasound molecular imaging as a non-invasive companion diagnostic for netrin-1 interference therapy in breast cancer |
Q35566324 | Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer |
Q34717001 | Whole-exome sequencing of muscle-invasive bladder cancer identifies recurrent mutations of UNC5C and prognostic importance of DNA repair gene mutations on survival |
Q97540643 | Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding motif (TAZ): a nexus between hypoxia and cancer |
Q36092830 | p53, apoptosis and axon-guidance molecules |
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