| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1049138476 |
| P356 | DOI | 10.1038/NATURE748 |
| P698 | PubMed publication ID | 11986622 |
| P5875 | ResearchGate publication ID | 11382801 |
| P50 | author | Marc Tessier-Lavigne | Q6755913 |
| P2093 | author name string | Patrick Mehlen | |
| Véronique Corset | |||
| Elke Stein | |||
| Christelle Forcet | |||
| Fabien Llambi | |||
| Laurent Pays | |||
| P2860 | cites work | Deleted in Colorectal Cancer (DCC) encodes a netrin receptor | Q24313278 |
| Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization | Q27863662 | ||
| Recycling of the cell adhesion molecule L1 in axonal growth cones. | Q27863668 | ||
| A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis. | Q27863669 | ||
| The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis | Q28116063 | ||
| Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor | Q28142063 | ||
| The Csk homologous kinase associates with TrkA receptors and is involved in neurite outgrowth of PC12 cells | Q28144152 | ||
| Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex | Q28203651 | ||
| Mammalian MAP kinase signalling cascades | Q28204140 | ||
| Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene | Q28236533 | ||
| In vivo expression and regulation of Elk-1, a target of the extracellular-regulated kinase signaling pathway, in the adult rat brain | Q28257720 | ||
| PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo | Q28609356 | ||
| Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system | Q29616040 | ||
| The molecular biology of axon guidance | Q29617857 | ||
| Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction | Q31813080 | ||
| Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation | Q32137183 | ||
| Organization and regulation of mitogen-activated protein kinase signaling pathways | Q33333640 | ||
| Microtubules and signal transduction | Q33536499 | ||
| A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion | Q33867499 | ||
| The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. | Q34332258 | ||
| Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord | Q34332262 | ||
| Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC. | Q34451947 | ||
| The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites | Q40756366 | ||
| Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway | Q40808897 | ||
| The p38 MAP kinase inhibitor SB203580 enhances nuclear factor-kappa B transcriptional activity by a non-specific effect upon the ERK pathway | Q40858871 | ||
| Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation | Q43832078 | ||
| Neural cell adhesion molecule-stimulated neurite outgrowth depends on activation of protein kinase C and the Ras-mitogen-activated protein kinase pathway | Q73514875 | ||
| P433 | issue | 6887 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | colorectal cancer | Q188874 |
| P304 | page(s) | 443-447 | |
| P577 | publication date | 2002-05-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation | |
| P478 | volume | 417 |
| Q34159873 | A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding |
| Q39628839 | A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration |
| Q33834786 | A frazzled/DCC-dependent transcriptional switch regulates midline axon guidance |
| Q34575456 | A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth. |
| Q34494556 | A parallel genome-wide mRNA and microRNA profiling of the frontal cortex of HIV patients with and without HIV-associated dementia shows the role of axon guidance and downstream pathways in HIV-mediated neurodegeneration |
| Q48846417 | A signaling mechanism coupling netrin-1/deleted in colorectal cancer chemoattraction to SNARE-mediated exocytosis in axonal growth cones. |
| Q34360478 | Activation of FAK and Src are receptor-proximal events required for netrin signaling |
| Q36216011 | Amyloid precursor protein regulates netrin-1-mediated commissural axon outgrowth |
| Q34552993 | Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage. |
| Q44386910 | Apoptotic pathway and MAPKs differentially regulate chemotropic responses of retinal growth cones |
| Q90352851 | Association Analysis between Body Mass Index and Genomic DNA Methylation across 15 Major Cancer Types |
| Q28744477 | Autocrine netrin function inhibits glioma cell motility and promotes focal adhesion formation |
| Q24297077 | Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits |
| Q34383999 | Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration |
| Q40286050 | Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients |
| Q47068919 | C. elegans seu-1 encodes novel nuclear proteins that regulate responses to UNC-6/netrin guidance cues |
| Q37183760 | Colorectal carcinogenesis: Review of human and experimental animal studies |
| Q39963050 | Compartmentalized DCC signalling is distinct from DCC localized to lipid rafts |
| Q44831766 | Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1. |
| Q59058784 | DCC constrains tumour progression via its dependence receptor activity |
| Q37802881 | Deciphering proteins and their functions in the regenerating retina |
| Q38243917 | Dependence receptors and colorectal cancer. |
| Q41825402 | Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for glial and neural-related molecules in central nervous system mixed glial cell cultures: neurotrophins, growth factors and structural proteins |
| Q55286029 | ERK/MAPK and PI3K/AKT signal channels simultaneously activated in nerve cell and axon after facial nerve injury. |
| Q55048482 | Egr-1 increases angiogenesis in cartilage via binding Netrin-1 receptor DCC promoter. |
| Q28505876 | EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway |
| Q30359723 | EphA7 regulates spiral ganglion innervation of cochlear hair cells. |
| Q35157602 | Epithelial morphogenesis: Netrin comes to a sticky and terminal end. |
| Q28727027 | Ethanol disrupts axon outgrowth stimulated by netrin-1, GDNF, and L1 by blocking their convergent activation of Src family kinase signaling |
| Q34359934 | Expression of DCC and netrin-1 in normal human endometrium and its implication in endometrial carcinogenesis |
| Q38732929 | Expression of netrin-1 by hypoxia contributes to the invasion and migration of prostate carcinoma cells by regulating YAP activity |
| Q48091775 | Extracellular signal-regulated protein kinase in human intractable epilepsy |
| Q28288747 | Focal adhesion kinase in netrin-1 signaling |
| Q84209889 | Guidance of postural motoneurons requires MAPK/ERK signaling downstream of fibroblast growth factor receptor 1 |
| Q47831144 | Human TUBB3 Mutations Disrupt Netrin Attractive Signaling. |
| Q24647958 | Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies |
| Q46988399 | Induction of cellular growth by the axon guidance regulators netrin A and semaphorin-1a. |
| Q39884897 | Interference with netrin-1 and tumor cell death in non-small cell lung cancer |
| Q35172108 | Intracellular control of developmental and regenerative axon growth |
| Q35087183 | Introduction to cytoskeletal dynamics and pathfinding of neuronal growth cones |
| Q39967986 | Lipid raft localization and palmitoylation: identification of two requirements for cell death induction by the tumor suppressors UNC5H. |
| Q44831769 | Lipid rafts mediate chemotropic guidance of nerve growth cones |
| Q36545296 | MUC4-promoted neural invasion is mediated by the axon guidance factor Netrin-1 in PDAC |
| Q46196382 | Making Connections: Guidance Cues and Receptors at Nonneural Cell-Cell Junctions |
| Q28217897 | Manipulation of EphB2 regulatory motifs and SH2 binding sites switches MAPK signaling and biological activity |
| Q36539451 | Molecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury |
| Q35607397 | Molecular basis of otic commitment and morphogenesis: a role for homeodomain-containing transcription factors and signaling molecules |
| Q28506167 | Myosin X regulates netrin receptors and functions in axonal path-finding |
| Q92959355 | NTN1 Affects Porcine Intramuscular Fat Content by Affecting the Expression of Myogenic Regulatory Factors |
| Q37448278 | Neogenin regulates skeletal myofiber size and focal adhesion kinase and extracellular signal-regulated kinase activities in vivo and in vitro |
| Q36242120 | Nerve ending "signal" proteins GAP-43, MARCKS, and BASP1. |
| Q82133954 | Netrin PIPes up |
| Q37550625 | Netrin and DCC: axon guidance regulators at the intersection of nervous system development and cancer |
| Q34360468 | Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction |
| Q47374262 | Netrin-1 Prevents Rat Primary Cortical Neurons from Apoptosis via the DCC/ERK Pathway |
| Q24645254 | Netrin-1 acts as a survival factor for aggressive neuroblastoma |
| Q28295909 | Netrin-1 and its receptors in tumorigenesis |
| Q34308782 | Netrin-1 and semaphorin 3A promote or inhibit cortical axon branching, respectively, by reorganization of the cytoskeleton. |
| Q26799750 | Netrin-1 as a novel therapeutic target in cardiovascular disease: to activate or inhibit? |
| Q34345335 | Netrin-1 controls colorectal tumorigenesis by regulating apoptosis |
| Q35740352 | Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability |
| Q24657804 | Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer |
| Q39263105 | Netrin-1 in cancer: Potential biomarker and therapeutic target? |
| Q39884847 | Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor |
| Q33999073 | Netrin-1 induces MMP-12-dependent E-cadherin degradation via the distinct activation of PKCα and FAK/Fyn in promoting mesenchymal stem cell motility |
| Q34513279 | Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism |
| Q46598678 | Netrin-1 induces axon branching in developing cortical neurons by frequency-dependent calcium signaling pathways. |
| Q87126886 | Netrin-1 induces epithelial-mesenchymal transition and promotes hepatocellular carcinoma invasiveness |
| Q39894506 | Netrin-1 interacts with amyloid precursor protein and regulates amyloid-beta production |
| Q36399152 | Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation |
| Q36936345 | Netrin-1 is a survival factor during commissural neuron navigation |
| Q35640245 | Netrin-1 overexpression is predictive of ovarian malignancies |
| Q64121391 | Netrin-1 plays a role in the effect of moderate exercise on myocardial fibrosis in rats |
| Q35757999 | Netrin-1 promotes cell migration and invasion by down-regulation of BVES expression in human hepatocellular carcinoma. |
| Q36738102 | Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin α6β4-dependent Akt, GSK-3β, and HSF-1 in mesenchymal stem cells. |
| Q34442642 | Netrin-1 stimulates developing GnRH neurons to extend neurites to the median eminence in a calcium- dependent manner |
| Q37269416 | Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer |
| Q28298433 | Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate |
| Q34183568 | Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis |
| Q24676178 | Netrins and neogenin promote myotube formation |
| Q36759032 | Netrins: beyond the brain |
| Q43974880 | Neurobiology: a new way to network |
| Q57039772 | Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis |
| Q35068917 | Neurons take shape |
| Q34942342 | Neurotrophic factors and axonal growth |
| Q37235706 | New insights into the genetic mechanism of IQ in autism spectrum disorders |
| Q28291163 | Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis |
| Q49158725 | Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral artery occlusion |
| Q34776474 | Overexpression of netrin-1 induces neovascularization in the adult mouse brain |
| Q47831359 | PI3K/Akt and ERK/MAPK Signaling Promote Different Aspects of Neuron Survival and Axonal Regrowth Following Rat Facial Nerve Axotomy. |
| Q28591288 | Phosphatidylinositol transfer protein-alpha in netrin-1-induced PLC signalling and neurite outgrowth |
| Q36322746 | Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance |
| Q35861824 | Phosphorylation of Stim1 at serine 575 via netrin-2/Cdo-activated ERK1/2 is critical for the promyogenic function of Stim1 |
| Q38595350 | Plasticity-related genes in brain development and amygdala-dependent learning. |
| Q40460019 | Presenilin attenuates receptor-mediated signaling and synaptic function. |
| Q46961015 | Protein interacting with C-kinase 1/protein kinase Calpha-mediated endocytosis converts netrin-1-mediated repulsion to attraction. |
| Q44814716 | Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension. |
| Q53818447 | Receptors of intermediates of carbohydrate metabolism, GPR91 and GPR99, mediate axon growth. |
| Q38637134 | Reciprocal antagonism between the netrin-1 receptor uncoordinated-phenotype-5A (UNC5A) and the hepatitis C virus |
| Q36718521 | Recognition molecules and neural repair |
| Q48250557 | Regulation of patterned dynamics of local exocytosis in growth cones by netrin-1. |
| Q37963374 | Role of GSK3 Signaling in Neuronal Morphogenesis |
| Q24631633 | Role of Unc51.1 and its binding partners in CNS axon outgrowth |
| Q42116932 | Sema3F downregulates p53 expression leading to axonal growth cone collapse in primary hippocampal neurons. |
| Q28592956 | Semaphorin 3A stimulates neurite extension and regulates gene expression in PC12 cells |
| Q47674521 | Semaphorin 3F antagonizes neurotrophin-induced phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase signaling: a mechanism for growth cone collapse. |
| Q40368258 | Semaphorin 4D activates the MAPK pathway downstream of plexin-B1. |
| Q91854213 | Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice |
| Q35610287 | Signalling mechanisms mediating neuronal responses to guidance cues |
| Q27684004 | Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism |
| Q40132068 | Synapsins Are Downstream Players of the BDNF-Mediated Axonal Growth |
| Q36301844 | Synaptic vesicle clustering requires a distinct MIG-10/Lamellipodin isoform and ABI-1 downstream from Netrin. |
| Q48389546 | Syntaxin 1 is required for DCC/Netrin-1-dependent chemoattraction of migrating neurons from the lower rhombic lip. |
| Q47636765 | Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain |
| Q48502109 | Targeting Netrin-1 in glioblastoma stem-like cells inhibits growth, invasion, and angiogenesis. |
| Q46178046 | The axon guidance molecule Netrin-4 is expressed by Müller cells and contributes to angiogenesis in the retina |
| Q24545021 | The dependence receptor DCC requires lipid raft localization for cell death signaling |
| Q24555713 | The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase |
| Q24318638 | The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase |
| Q36406518 | The extracellular matrix provides directional cues for neuronal migration during cerebellar development. |
| Q33327050 | The neogenin intracellular domain regulates gene transcription via nuclear translocation |
| Q24683182 | The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment |
| Q34282154 | The tripartite motif protein MADD-2 functions with the receptor UNC-40 (DCC) in Netrin-mediated axon attraction and branching. |
| Q34856370 | Translating axon guidance cues. |
| Q35566324 | Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer |
| Q97540643 | Yes-associated protein (YAP) and transcriptional coactivator with a PDZ-binding motif (TAZ): a nexus between hypoxia and cancer |
| Q36543785 | c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance |
| Q30009048 | p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance |
Search more.