Dependence receptors and colorectal cancer.

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Dependence receptors and colorectal cancer. is …
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scholarly articleQ13442814

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P356DOI10.1136/GUTJNL-2013-306704
P698PubMed publication ID25163468
P5875ResearchGate publication ID265136077

P50authorServane Tauszig-DelamasureQ58946367
P2093author name stringPatrick Mehlen
P2860cites workCancer genome landscapesQ22242276
The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung diseaseQ22254713
The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinaseQ24318638
Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancersQ24338589
The dependence receptor UNC5H2 mediates apoptosis through DAP-kinaseQ24555713
Mutation and cancer: statistical study of retinoblastomaQ24618185
Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosisQ24642741
Netrin-1 acts as a survival factor for aggressive neuroblastomaQ24645254
Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignanciesQ24647958
Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancerQ24657804
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitmentQ24683182
Sonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activityQ27317023
Regorafenib in metastatic colorectal cancer.Q27852864
The consensus coding sequences of human breast and colorectal cancersQ27861035
The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysisQ28116063
Oncogenic kinase signallingQ28189493
Mutational analysis of the tyrosine kinome in colorectal cancersQ28203425
p53RDL1 regulates p53-dependent apoptosisQ28211258
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) geneQ28236533
Metastasis: a question of life or deathQ28242176
Identification of a chromosome 18q gene that is altered in colorectal cancersQ28274172
Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does notQ28580677
The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in miceQ28592320
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancerQ29614599
The Patched dependence receptor triggers apoptosis through a DRAL-caspase-9 complexQ33748985
Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.Q33949395
A randomized phase II trial of vismodegib versus placebo with FOLFOX or FOLFIRI and bevacizumab in patients with previously untreated metastatic colorectal cancerQ34034042
Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activationQ34126386
Global patterns of cancer incidence and mortality rates and trendsQ34127168
Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway functionQ34191681
Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehogQ34220947
Trk receptor tyrosine kinases: a bridge between cancer and neural developmentQ34296129
Dependence receptor TrkC is a putative colon cancer tumor suppressor.Q34323861
Role of the dependence receptor DCC in colorectal cancer pathogenesisQ34341063
Netrin-1 controls colorectal tumorigenesis by regulating apoptosisQ34345335
Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regressionQ34351731
The intestinal crypt, a prototype stem cell compartmentQ34358606
Allelotype of colorectal carcinomasQ34461209
The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm.Q34661111
NTRK3 is a potential tumor suppressor gene commonly inactivated by epigenetic mechanisms in colorectal cancerQ34845629
Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancerQ35566324
The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth.Q35752727
Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastomaQ36009277
Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9.Q36068851
Targeting signal transduction pathways in colorectal cancer--more than skin deepQ36184347
Tumor suppressor geneticsQ36252762
RET is a potential tumor suppressor gene in colorectal cancerQ36301488
Suppressed tumorigenicity of human endometrial cancer cells by the restored expression of the DCC geneQ36621039
Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progressionQ37386029
Evaluation of the colorectal cancer risk conferred by rare UNC5C alleles.Q37454450
Sunitinib: a multitargeted receptor tyrosine kinase inhibitor in the era of molecular cancer therapiesQ37628647
Dependence receptors: a new paradigm in cell signaling and cancer therapyQ37696275
Novel roles for Slits and netrins: axon guidance cues as anticancer targets?Q37843457
The utility of hedgehog signaling pathway inhibition for cancerQ38031211
Tyrosine kinase inhibitors: views of selectivity, sensitivity, and clinical performanceQ38050173
Role of cMET in the development and progression of colorectal cancerQ38134309
Hh pathway expression in human gut tissues and in inflammatory gut diseasesQ38445499
Promoter CpG island methylation of RET predicts poor prognosis in stage II colorectal cancer patientsQ39021801
Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumoursQ39391784
Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cellsQ39751251
Interference with netrin-1 and tumor cell death in non-small cell lung cancerQ39884897
Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivoQ39943105
A newly identified dependence receptor UNC5H4 is induced during DNA damage-mediated apoptosis and transcriptional target of tumor suppressor p53.Q39993348
Amplification of apoptosis through sequential caspase cleavage of the MET tyrosine kinase receptorQ40191055
Cellular effects of imatinib on medullary thyroid cancer cells harboring multiple endocrine neoplasia Type 2A and 2B associated RET mutationsQ40266118
The patched gene in development and cancerQ41732756
Caspase-generated fragment of the Met receptor favors apoptosis via the intrinsic pathway independently of its tyrosine kinase activity.Q42911687
DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular studyQ44210955
The DCC protein and prognosis in colorectal cancerQ44846916
Chromosome 18q allelic loss and prognosis in stage II and III colon cancerQ47705314
Aberrant methylation of the netrin-1 receptor genes UNC5C and DCC detected in advanced colorectal cancer.Q51799719
Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice.Q53278220
DAPK promotor methylation is an early event in colorectal carcinogenesis.Q53353154
Molecular co-expression of the c-Met oncogene and hepatocyte growth factor in primary colon cancer predicts tumor stage and clinical outcome.Q54584505
DCC constrains tumour progression via its dependence receptor activityQ59058784
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
P304page(s)1821-1829
P577publication date2014-08-27
P1433published inGutQ5621669
P1476titleDependence receptors and colorectal cancer
P478volume63