Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours

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Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1011357748
P356DOI10.1038/NATURE10790
P8608Fatcat IDrelease_5pnyvsgk6bgndcpzlx6ymrw3b4
P698PubMed publication ID22358843
P5875ResearchGate publication ID221855375

P2093author name stringJos Jonkers
Anton Berns
Ji-Ying Song
Paul Krimpenfort
Natalie Proost
John Zevenhoven
P2860cites workDeleted in Colorectal Cancer (DCC) encodes a netrin receptorQ24313278
Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancerQ24657804
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitmentQ24683182
The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysisQ28116063
Lessons from hereditary colorectal cancerQ28131788
p53RDL1 regulates p53-dependent apoptosisQ28211258
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) geneQ28236533
The DCC gene: structural analysis and mutations in colorectal carcinomasQ28253945
Identification of a chromosome 18q gene that is altered in colorectal cancersQ28274172
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous systemQ29616040
A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsionQ33867499
Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer.Q34069798
Role of the dependence receptor DCC in colorectal cancer pathogenesisQ34341063
Netrin-1 controls colorectal tumorigenesis by regulating apoptosisQ34345335
Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancerQ35901185
Prognostic value of genomic alterations in minimal residual cancer cells purified from the blood of breast cancer patientsQ36621664
Identification of UNC5A as a novel transcriptional target of tumor suppressor p53 and a regulator of apoptosisQ39717924
Interference with netrin-1 and tumor cell death in non-small cell lung cancerQ39884897
A newly identified dependence receptor UNC5H4 is induced during DNA damage-mediated apoptosis and transcriptional target of tumor suppressor p53.Q39993348
Evidence supporting exclusion of the DCC gene and a portion of chromosome 18q as the locus for susceptibility to hereditary nonpolyposis colorectal carcinoma in five kindredsQ41157926
Compound disruption of smad2 accelerates malignant progression of intestinal tumors in apc knockout miceQ44183137
Netrin and netrin receptor expression in the embryonic mammalian nervous system suggests roles in retinal, striatal, nigral, and cerebellar developmentQ48055792
Differential expression of DCC mRNA in adult rat forebrainQ48621904
Aberrant methylation of the UNC5C gene is frequently detected in advanced colorectal cancer.Q51745297
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.Q52544495
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.Q53588886
Smad4 haploinsufficiency in mouse models for intestinal cancerQ62977739
Putative cancer gene shows up in development insteadQ73333928
P433issue7386
P407language of work or nameEnglishQ1860
P921main subjectcolorectal carcinomaQ25493920
P304page(s)538-541
P577publication date2012-02-22
P1433published inNatureQ180445
P1476titleDeleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours
P478volume482

Reverse relations

cites work (P2860)
Q53346007Cohypermethylation of p14 in combination with CADM1 or DCC as a recurrence-related prognostic indicator in stage I esophageal squamous cell carcinoma.
Q38738177DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218.
Q47665714DCC Receptors Drive Prefrontal Cortex Maturation by Determining Dopamine Axon Targeting in Adolescence
Q34641317Deleted in Colorectal Cancer (DCC) pathfinding: axon guidance gene finally turned tumor suppressor
Q89967063Dependence and Guidance Receptors-DCC and Neogenin-In Partial EMT and the Actions of Serine Proteases
Q38243917Dependence receptors and colorectal cancer.
Q24607661Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
Q37362753Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study
Q39475504Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice
Q48322745Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression
Q38711222Impact of DCC (rs714) and PSCA (rs2294008 and rs2976392) Gene Polymorphism in Modulating Cancer Risk in Asian Population
Q37141368Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference.
Q48154272Loss of Dcc in the Spinal Cord is Sufficient to Cause a Deficit in Lateralized Motor Control and the Switch to a Hopping Gait.
Q35994740Microarray Expression Data Identify DCC as a Candidate Gene for Early Meningioma Progression
Q33844512Microbial carcinogenic toxins and dietary anti-cancer protectants
Q90292677Microbiota Profile and Impact of Fusobacterium nucleatum in Colorectal Cancer Patients of Barretos Cancer Hospital
Q34766640Microenvironmental Influences on Metastasis Suppressor Expression and Function during a Metastatic Cell's Journey
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Q47843948Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.
Q57490348Netrin Signaling Defines the Regional Border in the Drosophila Visual Center
Q33808151Netrin-1 controls sympathetic arterial innervation.
Q35125199Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases
Q46277359Netrin-1 is a novel regulator of vascular endothelial function in diabetes
Q35877709Netrin-1 regulates somatic cell reprogramming and pluripotency maintenance
Q30849516Non cell-autonomous role of DCC in the guidance of the corticospinal tract at the midline.
Q38673797Non-canonical NOTCH3 signalling limits tumour angiogenesis.
Q91704583Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus
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Q45353589Role of genetic variants of deleted in colorectal carcinoma (DCC) polymorphisms and esophageal and gastric cancers risk in Kashmir Valley and meta-analysis
Q36156772Selective depletion of tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin by environmental and endogenous serine proteases: linking diet and cancer
Q58593569Serine protease modulation of Dependence Receptors and EMT protein expression
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Q42256579Structure and Function of p53-DNA Complexes with Inactivation and Rescue Mutations: A Molecular Dynamics Simulation Study
Q36525869Targeting netrin-1/DCC interaction in diffuse large B-cell and mantle cell lymphomas
Q33358945The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue.
Q30540534The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo
Q30437910dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

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