| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1017/S1462399410001481 |
| P698 | PubMed publication ID | 20504380 |
| P50 | author | Merlin Thomas | Q56991969 |
| P2093 | author name string | Wendy C Burns | |
| P2860 | cites work | Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads | Q24291512 |
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| Connective Tissue Growth Factor Expressed in Tubular Epithelium Plays a Pivotal Role in Renal Fibrogenesis | Q57691320 | ||
| Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney | Q58214852 | ||
| Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation | Q61854900 | ||
| Augmented cytoplasmic Smad4 induces acceleration of TGF-?1 signaling in renal tubulointerstitial cells of hereditary nephrotic ICGN mice with chronic renal fibrosis; possible role for myofibroblastic differentiation | Q79292426 | ||
| Role of the phosphatidylinositol 3-kinase and mTOR pathways in the regulation of renal fibroblast function and differentiation | Q80263440 | ||
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| Imbalance of growth factor signalling in diabetic kidney disease: is connective tissue growth factor (CTGF, CCN2) the perfect intervention point? | Q81014504 | ||
| TGF-beta1-induced EMT can occur independently of its proapoptotic effects and is aided by EGF receptor activation | Q82040208 | ||
| Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy | Q44445070 | ||
| BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury | Q44479221 | ||
| Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice | Q45091472 | ||
| Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model | Q45862411 | ||
| Regression of advanced diabetic nephropathy by hepatocyte growth factor gene therapy in rats | Q45874042 | ||
| Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury | Q46073081 | ||
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| Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis | Q46853953 | ||
| Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis | Q47578416 | ||
| Adenoviral gene transfer of BMP-7, Id2, or Id3 suppresses injury-induced epithelial-to-mesenchymal transition of lens epithelium in mice | Q48791457 | ||
| Long-term follow-up after tight control of blood pressure in type 2 diabetes. | Q51122414 | ||
| Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum. | Q52561638 | ||
| Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice. | Q52590979 | ||
| Atubular glomeruli in patients with chronic allograft rejection. | Q53988633 | ||
| HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition | Q24318681 | ||
| TGF beta signals through a heteromeric protein kinase receptor complex | Q24337608 | ||
| Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism | Q24600173 | ||
| The epithelial-mesenchymal transition: new insights in signaling, development, and disease | Q24683758 | ||
| Epithelial-mesenchymal transitions in development and disease | Q27860630 | ||
| Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model | Q28142724 | ||
| Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail | Q28187811 | ||
| TGF-beta signal transduction and mesangial cell fibrogenesis | Q28203185 | ||
| Smad-dependent and Smad-independent pathways in TGF-beta family signalling | Q28208250 | ||
| The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor is a receptor for connective tissue growth factor | Q28214235 | ||
| Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function | Q28215638 | ||
| A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation | Q28265320 | ||
| Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA | Q28298502 | ||
| DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells | Q28304564 | ||
| Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE) | Q28366662 | ||
| Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney | Q28505069 | ||
| Connective tissue growth factor is secreted through the Golgi and is degraded in the endosome | Q28578100 | ||
| Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro | Q28579283 | ||
| 10-year follow-up of intensive glucose control in type 2 diabetes | Q29615973 | ||
| TGF-beta and epithelial-to-mesenchymal transitions | Q29616456 | ||
| The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion | Q29616467 | ||
| Evidence that fibroblasts derive from epithelium during tissue fibrosis | Q29616581 | ||
| Transcriptional control by the TGF-beta/Smad signaling system | Q29618985 | ||
| How cells read TGF-beta signals | Q29619993 | ||
| Non-Smad pathways in TGF-beta signaling | Q29620040 | ||
| Influence of connective tissue growth factor antisense oligonucleotide on angiotensin II-induced epithelial mesenchymal transition in HK2 cells | Q33251736 | ||
| Fibrotic myofibroblasts manifest genome-wide derangements of translational control | Q33369846 | ||
| TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition | Q33734595 | ||
| Specificity, diversity, and regulation in TGF-beta superfamily signaling. | Q33792305 | ||
| Signaling inputs converge on nuclear effectors in TGF-beta signaling | Q33832063 | ||
| Tubulointerstitial damage leads to atubular glomeruli: significance and possible role in progression | Q34121934 | ||
| TGF-beta control of cell proliferation | Q34441563 | ||
| Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice | Q34514594 | ||
| tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis | Q34736911 | ||
| TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest | Q34789115 | ||
| Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis | Q39814662 | ||
| Snail is required for TGFbeta-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells | Q39939184 | ||
| Pharmacological modulation of epithelial mesenchymal transition caused by angiotensin II. Role of ROCK and MAPK pathways. | Q39960357 | ||
| Co-regulation of Gremlin and Notch signalling in diabetic nephropathy | Q40057436 | ||
| Inhibition of integrin-linked kinase via a siRNA expression plasmid attenuates connective tissue growth factor-induced human proximal tubular epithelial cells to mesenchymal transition | Q40064241 | ||
| Role of ERK1/2 and PI3-K in the regulation of CTGF-induced ILK expression in HK-2 cells | Q40133623 | ||
| EMT or apoptosis: a decision for TGF-beta | Q40147080 | ||
| Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease. | Q40242733 | ||
| The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells. | Q40357523 | ||
| Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor | Q40389246 | ||
| Transformations between epithelium and mesenchyme: normal, pathological, and experimentally induced | Q40421321 | ||
| Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. | Q40464612 | ||
| A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition | Q40493463 | ||
| Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. | Q40560477 | ||
| Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. | Q40660373 | ||
| The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors | Q40680001 | ||
| Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation | Q40728276 | ||
| Interleukin-1 induces tubular epithelial-myofibroblast transdifferentiation through a transforming growth factor-beta1-dependent mechanism in vitro. | Q40818094 | ||
| Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8). | Q41029521 | ||
| Connective tissue growth factor. Friend or foe? | Q41596354 | ||
| Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts | Q41700398 | ||
| Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. | Q42492769 | ||
| Fuzheng Huayu recipe and vitamin E reverse renal interstitial fibrosis through counteracting TGF-beta1-induced epithelial-to-mesenchymal transition | Q43218540 | ||
| Epithelial-mesenchymal transition of tubular epithelial cells in human renal biopsies | Q44039616 | ||
| RhoGTPase activation is a key step in renal epithelial mesenchymal transdifferentiation | Q44365794 | ||
| TGF-beta signaling in renal disease | Q34869314 | ||
| Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells | Q35032352 | ||
| Regulation of TGF-beta signaling and its roles in progression of tumors | Q35161752 | ||
| Reactive oxygen species and matrix remodeling in diabetic kidney | Q35182366 | ||
| Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention | Q35615604 | ||
| Dual role of SnoN in mammalian tumorigenesis | Q35641680 | ||
| MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. | Q35652362 | ||
| Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis | Q35746891 | ||
| Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation | Q35746896 | ||
| Connective tissue growth factor and renal diseases: some answers, more questions | Q35748402 | ||
| Cellular origins of fibroblasts: possible implications for organ fibrosis in systemic sclerosis | Q35971144 | ||
| New insights into epithelial-mesenchymal transition in kidney fibrosis | Q36010095 | ||
| Apoptosis in podocytes induced by TGF-beta and Smad7 | Q36041187 | ||
| Tubular changes in early diabetic nephropathy. | Q36094480 | ||
| Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition. | Q36118227 | ||
| Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells | Q36223889 | ||
| Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta | Q36232185 | ||
| Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cells | Q36236279 | ||
| Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity | Q36857841 | ||
| The role of tubular epithelial-mesenchymal transition in progressive kidney disease. | Q36857879 | ||
| Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction | Q36991087 | ||
| A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition | Q37162704 | ||
| Biomarkers for epithelial-mesenchymal transitions | Q37209254 | ||
| Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition | Q37258903 | ||
| Clinical review 2: The "metabolic memory": is more than just tight glucose control necessary to prevent diabetic complications? | Q37344529 | ||
| Ski and SnoN, potent negative regulators of TGF-beta signaling | Q37359949 | ||
| Role of SARA (SMAD anchor for receptor activation) in maintenance of epithelial cell phenotype. | Q37375763 | ||
| Expression and activity of phosphodiesterase isoforms during epithelial mesenchymal transition: the role of phosphodiesterase 4. | Q37420468 | ||
| Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. | Q37504561 | ||
| Direct contribution of epithelium to organ fibrosis: epithelial-mesenchymal transition | Q37583186 | ||
| Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation | Q38289991 | ||
| Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-beta1 in human renal epithelial cells | Q38307188 | ||
| Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2. | Q38325122 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pathophysiology | Q1135939 |
| P304 | page(s) | e17 | |
| P577 | publication date | 2010-05-27 | |
| P1433 | published in | Expert Reviews in Molecular Medicine | Q15755244 |
| P1476 | title | The molecular mediators of type 2 epithelial to mesenchymal transition (EMT) and their role in renal pathophysiology | |
| P478 | volume | 12 |
| Q37593950 | Allicin inhibits tubular epithelial-myofibroblast transdifferentiation under high glucose conditions in vitro |
| Q92628672 | Amyloid β precursor protein silencing attenuates epithelial‑mesenchymal transition of nasopharyngeal carcinoma cells via inhibition of the MAPK pathway |
| Q34747187 | Astragaloside IV attenuates glycated albumin-induced epithelial-to-mesenchymal transition by inhibiting oxidative stress in renal proximal tubular cells |
| Q38785733 | CTGF mediates high-glucose induced epithelial-mesenchymal transition through activation of β-catenin in podocytes |
| Q35903772 | Cellular and molecular mechanisms of renal fibrosis |
| Q35740959 | Chromosomal imbalances revealed in primary renal cell carcinomas by comparative genomic hybridization. |
| Q37466825 | Class I HDACs specifically regulate E-cadherin expression in human renal epithelial cells |
| Q42022563 | Connective tissue growth factor in tumor pathogenesis. |
| Q37714689 | Diet-induced increase in plasma oxidized LDL promotes early fibrosis in a renal porcine auto-transplantation model |
| Q55025044 | Early Growth Response 1 (Egr1) Is a Transcriptional Activator of NOX4 in Oxidative Stress of Diabetic Kidney Disease. |
| Q26771698 | Emerging Transcriptional Mechanisms in the Regulation of Epithelial to Mesenchymal Transition and Cellular Plasticity in the Kidney |
| Q38075029 | Emerging drugs for managing kidney disease in patients with diabetes. |
| Q30370588 | Epidermal growth factor inhibits transforming growth factor-β-induced fibrogenic differentiation marker expression through ERK activation. |
| Q36423455 | FTO modulates fibrogenic responses in obstructive nephropathy |
| Q54353495 | Indoxyl sulfate induces epithelial-to-mesenchymal transition in rat kidneys and human proximal tubular cells. |
| Q92944994 | Injectable and Gellable Chitosan Formulations Filled with Cellulose Nanofibers for Intervertebral Disc Tissue Engineering |
| Q43762473 | Kindlin-2 regulates renal tubular cell plasticity by activation of Ras and its downstream signaling |
| Q33634028 | Mast Cells and MCPT4 Chymase Promote Renal Impairment after Partial Ureteral Obstruction. |
| Q38127775 | Matrix mechanics and regulation of the fibroblast phenotype |
| Q39194879 | MiRNA-200b represses transforming growth factor-β1-induced EMT and fibronectin expression in kidney proximal tubular cells |
| Q37899907 | New approaches to the treatment of nephropathy in diabetes |
| Q38059265 | Nintedanib (BIBF 1120) for IPF: a tomorrow therapy? |
| Q37195998 | Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1 |
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| Q36758028 | Renal integrin-linked kinase depletion induces kidney cGMP axis upregulation: Consequences on basal and acutely damaged renal function |
| Q36766772 | SNAI1 promotes the development of HCC through the enhancement of proliferation and inhibition of apoptosis |
| Q39251967 | SOCS-3 is downregulated in progressive CKD patients and regulates proliferation in human renal proximal tubule cells in a STAT1/3 independent manner |
| Q37733670 | The myofibroblast matrix: implications for tissue repair and fibrosis. |
| Q39474702 | The roles of connective tissue growth factor and integrin-linked kinase in high glucose-induced phenotypic alterations of podocytes |
| Q38983344 | Thimerosal induces apoptotic and fibrotic changes to kidney epithelial cells in vitro. |
| Q64123052 | Towards control of cellular decision-making networks in the epithelial-to-mesenchymal transition |
| Q35745099 | Transmembrane-Bound IL-15-Promoted Epithelial-Mesenchymal Transition in Renal Cancer Cells Requires the Src-Dependent Akt/GSK-3β/β-Catenin Pathway |
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| Q54355169 | Urinary mRNA markers of epithelial-mesenchymal transition correlate with progression of diabetic nephropathy. |
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