Ceftobiprole: A novel, broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus

scientific article published on June 2010

Ceftobiprole: A novel, broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2146/AJHP090285
P698PubMed publication ID20516468

P2093author name stringDaniel G Dauner
Robert E Nelson
Donna C Taketa
P2860cites workIn vitro and in vivo properties of Ro 63-9141, a novel broad-spectrum cephalosporin with activity against methicillin-resistant staphylococciQ24550612
Tigecycline: a new glycylcycline antimicrobial agentQ28247555
Invasive methicillin-resistant Staphylococcus aureus infections in the United StatesQ29616087
In vitro evaluation of BAL9141, a novel parenteral cephalosporin active against oxacillin-resistant staphylococciQ34162130
Binding of ceftobiprole and comparators to the penicillin-binding proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniaeQ34624359
PBP 2a mutations producing very-high-level resistance to beta-lactamsQ35547377
Probability of target attainment for ceftobiprole as derived from a population pharmacokinetic analysis of 150 subjectsQ35879080
Results of a double-blind, randomized trial of ceftobiprole treatment of complicated skin and skin structure infections caused by gram-positive bacteria.Q36422630
Pharmacologic treatment options for nosocomial pneumonia involving methicillin-resistant Staphylococcus aureus.Q36735202
Anti-MRSA beta-lactams in development, with a focus on ceftobiprole: the first anti-MRSA beta-lactam to demonstrate clinical efficacyQ36763997
In-vitro profile of a new beta-lactam, ceftobiprole, with activity against methicillin-resistant Staphylococcus aureusQ36815290
Clinical profile of ceftobiprole, a novel beta-lactam antibioticQ36815295
Alternatives to vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infectionsQ36916071
In vivo pharmacodynamics of ceftobiprole against multiple bacterial pathogens in murine thigh and lung infection modelsQ36932924
Pharmacokinetics and pharmacodynamics of ceftobiprole, an anti-MRSA cephalosporin with broad-spectrum activityQ37030780
Efficacy of BAL5788, a prodrug of cephalosporin BAL9141, in a mouse model of acute pneumococcal pneumoniaQ37119259
Use of Monte Carlo simulations to select therapeutic doses and provisional breakpoints of BAL9141.Q37733667
In vitro activity of ceftobiprole against aerobic and anaerobic strains isolated from diabetic foot infectionsQ39077347
Postantibiotic effect of ceftobiprole against 12 Gram-positive organismsQ39077719
BAL9141, a novel extended-spectrum cephalosporin active against methicillin-resistant Staphylococcus aureus in treatment of experimental endocarditisQ39650937
Single-dose pharmacokinetics and safety of a novel broad-spectrum cephalosporin (BAL5788) in healthy volunteersQ40967997
Multiple-dose pharmacokinetics and safety of a novel broad-spectrum cephalosporin (BAL5788) in healthy volunteersQ40968003
Evaluation of ceftobiprole in a rabbit model of aortic valve endocarditis due to methicillin-resistant and vancomycin-intermediate Staphylococcus aureusQ41092910
Activities of ceftobiprole, linezolid, vancomycin, and daptomycin against community-associated and hospital-associated methicillin-resistant Staphylococcus aureusQ41336401
Activities of ceftobiprole and other beta-lactams against Streptococcus pneumoniae clinical isolates from the United States with defined substitutions in penicillin-binding proteins PBP 1a, PBP 2b, and PBP 2x.Q41473443
Antistaphylococcal activity of ceftobiprole, a new broad-spectrum cephalosporinQ41847350
Antipneumococcal activity of ceftobiprole, a novel broad-spectrum cephalosporinQ42112713
Interactions of ceftobiprole with beta-lactamases from molecular classes A to D.Q42584480
Time-kill and synergism studies of ceftobiprole against Enterococcus faecalis, including beta-lactamase-producing and vancomycin-resistant isolatesQ42747697
Antimicrobial activity of ceftobiprole, a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin, tested against contemporary pathogens: results from the SENTRY Antimicrobial Surveillance Program (2005-2006).Q46667419
A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infectionsQ46787486
In vitro activity profile of ceftobiprole, an anti-MRSA cephalosporin, against recent gram-positive and gram-negative isolates of European originQ46792584
Methicillin-ResistantS. aureusInfections among Patients in the Emergency DepartmentQ55897489
Linezolid: an oxazolidinone antimicrobial agentQ78721705
In vitro activity of ceftobiprole, daptomycin, linezolid, and vancomycin against methicillin-resistant staphylococci associated with endocarditis and bone and joint infectionQ80193908
Evaluation of ceftobiprole medocaril against Enterococcus faecalis in a mouse peritonitis modelQ80557153
P433issue12
P921main subjectStaphylococcus aureusQ188121
methicillin-resistant Staphylococcus aureusQ595158
P304page(s)983-993
P577publication date2010-06-01
P1433published inAmerican Journal of Health-System PharmacyQ15754037
P1476titleCeftobiprole: A novel, broad-spectrum cephalosporin with activity against methicillin-resistant Staphylococcus aureus
P478volume67

Reverse relations

cites work (P2860)
Q37916805Advances in antibacterial therapy
Q35117981Ceftaroline: A New Cephalosporin with Activity against Methicillin-Resistant Staphylococcus aureus (MRSA)
Q26796463Ceftobiprole for the treatment of pneumonia: a European perspective
Q43048139Ceftobiprole: Farewell or just a delay?
Q38242081Current and emerging drugs for acute bacterial skin and skin structure infections: an update
Q55443184In silico study on Penicillin derivatives and Cephalosporins for upper respiratory tract bacterial pathogens.
Q38035171Inhibitors targeting on cell wall biosynthesis pathway of MRSA.
Q92304798Mechanisms of action and antimicrobial activity of ceftobiprole
Q38099393Pharmacokinetic and pharmacodynamics evaluation of ceftobiprole medocaril for the treatment of hospital-acquired pneumonia.
Q28066877Pharmacokinetics and Dosing of Ceftobiprole Medocaril for the Treatment of Hospital- and Community-Acquired Pneumonia in Different Patient Populations
Q40049973Treatment of Staphylococcus aureus Infections
Q38462842Vancomycin in the treatment of methicillin-resistant Staphylococcus aureus - a clinician's guide to the science informing current practice

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