Label-free whole-cell assays: expanding the scope of GPCR screening

scientific article published on 23 June 2010

Label-free whole-cell assays: expanding the scope of GPCR screening is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.DRUDIS.2010.06.008
P698PubMed publication ID20601093
P5875ResearchGate publication ID45092214

P2093author name stringClay W Scott
Matthew F Peters
P433issue17-18
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)704-716
P577publication date2010-06-23
P1433published inDrug Discovery TodayQ3040085
P1476titleLabel-free whole-cell assays: expanding the scope of GPCR screening
P478volume15

Reverse relations

cites work (P2860)
Q30420969A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling.
Q50101527A novel microfluidic microelectrode chip for a significantly enhanced monitoring of NPY-receptor activation in live mode.
Q28740731Agonist-directed desensitization of the β2-adrenergic receptor
Q36841982Allosteric modulation and functional selectivity of G protein-coupled receptors.
Q51513968Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells.
Q51601857Are we just learning the scales on the chemokine receptor pianos?
Q46911058Buserelin alleviates chloride transport defect in human cystic fibrosis nasal epithelial cells
Q36463676C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay
Q45288843Cannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk
Q36301873Cell-impedance-based label-free technology for the identification of new drugs
Q39136383Combined optical and electronic sensing of epithelial cells using planar organic transistors
Q38926032Detection and quantification of allosteric modulation of endogenous m4 muscarinic acetylcholine receptor using impedance-based label-free technology in a neuronal cell line.
Q36311216Development of a test that measures real-time HER2 signaling function in live breast cancer cell lines and primary cells
Q36294093Development of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model
Q37263512Effects for Sequential Treatment of siAkt and Paclitaxel on Gastric Cancer Cell Lines.
Q35529100Emergence of Chinese drug discovery research: impact of hit and lead identification
Q38192536Experimental tools to monitor the dynamics of endothelial barrier function: a survey of in vitro approaches
Q37648861GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts
Q24319705Galanin pathogenic mutations in temporal lobe epilepsy
Q34953430Heteromerization of GPR55 and cannabinoid CB2 receptors modulates signalling
Q38925674Holistic Methods for the Analysis of cNMP Effects
Q58551148Human 3D Gastrointestinal Microtissue Barrier Function as a Predictor of Drug-Induced Diarrhea
Q38240972Human stem cell-derived cardiomyocytes in cellular impedance assays: bringing cardiotoxicity screening to the front line.
Q38777517Intensity interrogation near cutoff resonance for label-free cellular profiling.
Q41773603Kinetics of the early events of GPCR signalling
Q50569577Label-Free Dynamic Mass Redistribution and Bio-Impedance Methods for Drug Discovery.
Q42839383Label-Free Imaging of Histamine Mediated G Protein-Coupled Receptors Activation in Live Cells
Q39013350Label-free cell-based dynamic mass redistribution assays
Q90261793Label-free detection of transporter activity via GPCR signalling in living cells: A case for SLC29A1, the equilibrative nucleoside transporter 1
Q92850046Label-free dynamic mass redistribution analysis of endogenous adrenergic receptor signaling in primary preadipocytes and differentiated adipocytes
Q28709650Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family
Q28730612Label-free phenotypic profiling identified D-luciferin as a GPR35 agonist
Q38014954Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors
Q30656460Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs
Q33636151Novel delta opioid receptor agonists with oxazatricyclodecane structure
Q62657706Optimization of a Planar All-Polymer Transistor for Characterization of Barrier Tissue
Q31154360Potential strategies for increasing drug-discovery productivity.
Q47685791The development of label-free cellular assays for drug discovery
Q27007472Tools for GPCR drug discovery
Q35662230Tricyclic Antidepressant Amitriptyline-induced Glial Cell Line-derived Neurotrophic Factor Production Involves Pertussis Toxin-sensitive Gαi/o Activation in Astroglial Cells
Q46013288Troubleshooting and deconvoluting label-free cell phenotypic assays in drug discovery.
Q51377000Using Biosensors to Study Free Fatty Acid Receptor Pharmacology and Function.
Q37999094Using label-free screening technology to improve efficiency in drug discovery

Search more.