Alpha-melanocyte stimulating hormone: production and degradation

scientific article published on 10 July 2010

Alpha-melanocyte stimulating hormone: production and degradation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00109-010-0651-0
P932PMC publication ID3936413
P698PubMed publication ID20617297

P50authorGiuseppe D'AgostinoQ56998462
P2093author name stringSabrina Diano
P2860cites workAntagonism of central melanocortin receptors in vitro and in vivo by agouti-related proteinQ24314579
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Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptidesQ28257807
A frameshift mutation in human MC4R is associated with a dominant form of obesityQ28285286
Targeted disruption of the melanocortin-4 receptor results in obesity in miceQ28302831
Intracellular signalling. Key enzyme in leptin-induced anorexiaQ28573472
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intakeQ28576714
The proprotein convertasesQ28609903
Sequencing and cloning of human prolylcarboxypeptidase (angiotensinase C). Similarity to both serine carboxypeptidase and prolylendopeptidase familiesQ28631220
Central nervous system control of food intake and body weightQ29619020
Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunctionQ44764463
The melanocortin agonist melanotan II increases insulin sensitivity in OLETF ratsQ45046311
Design, synthesis, and evaluation of proline based melanocortin receptor ligandsQ46505363
Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in miceQ46560723
PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress responseQ46658340
Overexpression of prolylcarboxypeptidase enhances plasma prekallikrein activation on Chinese hamster ovary cellsQ46661267
Optimization of a privileged structure leading to potent and selective human melanocortin subtype-4 receptor ligandsQ46859016
Role of brain insulin receptor in control of body weight and reproductionQ47229086
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Differential effects of fasting and leptin on proopiomelanocortin peptides in the arcuate nucleus and in the nucleus of the solitary tractQ48308139
Melanocortins and cardiovascular regulationQ48333394
Melanocortin receptors in leptin effectsQ48590178
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.Q53531526
Chemical characterization of leptin-activated neurons in the rat brainQ73925838
A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouseQ74244402
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body massQ74268345
Multiple linked mouse chromosome 7 loci influence body fat massQ79187337
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleusQ29619635
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in miceQ30481572
Hypothalamic Sirt1 regulates food intake in a rodent model systemQ33519539
The role of melanocortin signalling in the control of body weight: evidence from human and murine genetic models.Q33810057
Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.Q33873670
Peripheral administration of a melanocortin 4-receptor inverse agonist prevents loss of lean body mass in tumor-bearing miceQ33993122
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Evidence for substantial effect modification by gender in a large-scale genetic association study of the metabolic syndrome among coronary heart disease patientsQ34269759
Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient miceQ34312762
Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.Q34362234
Anatomy and regulation of the central melanocortin systemQ34414149
Neuropathic pain: a possible role for the melanocortin system?Q34430616
Membrane phospholipid control of nucleotide sensitivity of KATP channelsQ34478704
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesityQ34691534
Central insulin action in energy and glucose homeostasisQ34698802
Anti-obesity drugs and neural circuits of feeding.Q34763291
The need to feed: homeostatic and hedonic control of eatingQ34970647
Melanocortin ligands: 30 years of structure-activity relationship (SAR) studiesQ35679974
Targeting melanocortin receptors as a novel strategy to control inflammation.Q35682900
Proopiomelanocortin and energy balance: insights from human and murine geneticsQ35794437
The MC4 receptor and control of appetiteQ36054459
Melanocortinergic control of penile erectionQ36181835
A review of melanocortin receptor small molecule ligandsQ36211270
Roles of acetylation and other post-translational modifications in melanocortin function and interactions with endorphins.Q36310202
Brain SIRT1: anatomical distribution and regulation by energy availabilityQ36962837
Prolylcarboxypeptidase (angiotensinase C) in human lung and cultured cellsQ37026019
Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodentsQ37286620
N-acetylation of hypothalamic alpha-melanocyte-stimulating hormone and regulation by leptinQ37416108
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residuesQ37491584
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db miceQ38353583
Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter.Q40569723
Investigation of the melanocyte stimulating hormones on food intake. Lack Of evidence to support a role for the melanocortin-3-receptorQ40871995
Cellular carboxypeptidasesQ41745113
Neuropeptide-Y innervation of beta-endorphin-containing cells in the rat mediobasal hypothalamus: a light and electron microscopic double immunostaining analysisQ42456330
Neuropeptide Y innervation of ACTH-immunoreactive neurons in the arcuate nucleus of rats: a correlated light and electron microscopic double immunolabeling studyQ44014887
Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balanceQ44315321
P433issue12
P304page(s)1195-1201
P577publication date2010-07-10
P1433published inJournal of Molecular MedicineQ6295593
P1476titleAlpha-melanocyte stimulating hormone: production and degradation
P478volume88

Reverse relations

cites work (P2860)
Q34979873Alpha-melanocyte stimulating hormone (α-MSH) is a post-caspase suppressor of apoptosis in RAW 264.7 macrophages
Q47828534Analyzing the effects of co-expression of chick (Gallus gallus) melanocortin receptors with either chick MRAP1 or MRAP2 in CHO cells on sensitivity to ACTH(1-24) or ACTH(1-13)NH2: Implications for the avian HPA axis and avian melanocortin circuits i
Q34263329Carboxypeptidase E is a novel modulator of RANKL-induced osteoclast differentiation
Q28572486Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats
Q35088823Central Sirt1 regulates body weight and energy expenditure along with the POMC-derived peptide α-MSH and the processing enzyme CPE production in diet-induced obese male rats.
Q85209470Complex Catabolic Effects of Central Alpha-MSH Infusion in Rats of Altered Nutritional States: Differences from Leptin
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Q94533163Molecular evolution of the proopiomelanocortin system in Barn owl species
Q57044755Nucleus of the Solitary Tract Serotonin 5-HT Receptors Modulate Food Intake
Q90134164On-off switching of cell cycle and melanogenesis regulation of melanocytes by non-thermal atmospheric pressure plasma-activated medium
Q38862134PCSK1 Variants and Human Obesity
Q34049621Plasma α-melanocyte stimulating hormone predicts outcome in ischemic stroke.
Q39430460Prolylcarboxypeptidase (PrCP) inhibitors and the therapeutic uses thereof: a patent review
Q38791244Resolution of inflammation: a new therapeutic frontier
Q60923969α-Melanocyte-Stimulating Hormone Attenuates Neovascularization by Inducing Nitric Oxide Deficiency via MC-Rs/PKA/NF-κB Signaling

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