Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice

scientific article published on 22 June 2005

Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00125-005-1838-8
P698PubMed publication ID15971058
P5875ResearchGate publication ID7772487

P50authorAnnemieke C HeijboerQ41125724
Hanno PijlQ59211762
P2093author name stringL M Havekes
J A Romijn
H Pijl
E P M Corssmit
A M van den Hoek
P J Voshol
P2860cites workSingle-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
A frameshift mutation in MC4R associated with dominantly inherited human obesityQ28117916
A frameshift mutation in human MC4R is associated with a dominant form of obesityQ28285286
Role of melanocortinergic neurons in feeding and the agouti obesity syndromeQ28300979
Central melanocortin receptors regulate insulin actionQ28360753
Central nervous system control of food intakeQ29547439
New insights into sympathetic regulation of glucose and fat metabolismQ33905747
Role of melanocortins in control of obesityQ34377037
Neuropeptides, food intake and body weight regulation: a hypothalamic focusQ35048780
Selectivity of cyclic [D-Nal7] and [D-Phe7] substituted MSH analogues for the melanocortin receptor subtypesQ36889306
AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptorQ40833844
The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat.Q42435903
In muscle-specific lipoprotein lipase-overexpressing mice, muscle triglyceride content is increased without inhibition of insulin-stimulated whole-body and muscle-specific glucose uptakeQ43778803
Effects of acute and chronic administration of the melanocortin agonist MTII in mice with diet-induced obesityQ43972527
Food conversion is transiently affected during 4-week chronic administration of melanocortin agonist and antagonist in ratsQ44028436
Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses.Q44566038
Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese miceQ44631805
PYY3-36 reinforces insulin action on glucose disposal in mice fed a high-fat dietQ44995518
Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulinQ45077923
Is the energy homeostasis system inherently biased toward weight gain?Q47173540
The central melanocortin system can directly regulate serum insulin levelsQ47620409
Satiety effect and sympathetic activation of leptin are mediated by hypothalamic melanocortin systemQ47772359
Interactions between the melanocortin system and leptin in control of sympathetic nerve trafficQ48292251
Truncal vagotomy does not affect postabsorptive glucose metabolism in humans.Q51587612
Sex differences in the adaptation of glucose metabolism to short-term fasting: effects of oral contraceptives.Q51592470
Centrally administered MTII affects feeding, drinking, temperature, and activity in the Sprague-Dawley rat.Q52540034
Role of glucocorticoids and fatty acids in the impairment of lipid metabolism observed in the metabolic syndromeQ71721641
The NPY/AgRP neuron and energy homeostasisQ77628422
P433issue8
P921main subjectpreproinsulinQ7240673
P304page(s)1621-1626
P577publication date2005-06-22
P1433published inDiabetologiaQ5270140
P1476titleIntracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice
P478volume48

Reverse relations

cites work (P2860)
Q37771277Alpha-melanocyte stimulating hormone: production and degradation
Q35152229Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice
Q34615377Deletion of Lkb1 in pro-opiomelanocortin neurons impairs peripheral glucose homeostasis in mice
Q37429162Distinct effects of leptin and a melanocortin receptor agonist injected into medial hypothalamic nuclei on glucose uptake in peripheral tissues
Q46950221Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice
Q36640460Gut-brain axis: regulation of glucose metabolism
Q37808731Hypothalamic control of energy metabolism via the autonomic nervous system.
Q40212153Intermittent MTII application evokes repeated anorexia and robust fat and weight loss
Q36543067Investigational therapies in the treatment of obesity
Q33602487Leptin revisited: its mechanism of action and potential for treating diabetes
Q37314990Leptin-dependent control of glucose balance and locomotor activity by POMC neurons.
Q43210742Monitoring FoxO1 localization in chemically identified neurons
Q28301492Novel α-MSH analog causes weight loss in obese rats and minipigs and improves insulin sensitivity
Q104134945Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production
Q34076219Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity
Q35442056RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals
Q36138183Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways
Q35561118Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice
Q36054459The MC4 receptor and control of appetite
Q34517720The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity
Q36003378The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.
Q51475312Transgenic MSH overexpression attenuates the metabolic effects of a high-fat diet.

Search more.