Genomics and pharmacogenomics of schizophrenia

scientific article published on 16 August 2010

Genomics and pharmacogenomics of schizophrenia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1755-5949.2010.00187.X
P932PMC publication ID6493868
P698PubMed publication ID20718829

P50authorRamón CacabelosQ66809646
Rocio Martinez-BouzaQ121434345
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Decreased expression of Fyn protein and disbalanced alternative splicing patterns in platelets from patients with schizophrenia.Q45980108
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Effects of the CYP2D6*10 alleles and co-medication with CYP2D6-dependent drugs on risperidone metabolism in patients with schizophrenia.Q46039809
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Association between HTR2C and HTR2A polymorphisms and metabolic abnormalities in patients treated with olanzapine or clozapineQ46164331
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Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia.Q46176279
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Gender differences in schizophreniaQ48020725
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TATA box-binding protein gene is associated with risk for schizophrenia, age at onset and prefrontal functionQ48545410
Changes in alternative brain-derived neurotrophic factor transcript expression in the developing human prefrontal cortexQ48576041
A family-based study of the IL3RA gene on susceptibility to schizophrenia in a Chinese Han populationQ48707465
Elevated delta-6 desaturase (FADS2) expression in the postmortem prefrontal cortex of schizophrenic patients: relationship with fatty acid compositionQ48766110
Polymorphisms of the LEP- and LEPR gene and obesity in patients using antipsychotic medication.Q51662922
DNA methyltransferase 3B gene increases risk of early onset schizophreniaQ51866642
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Case-control study of association between the functional candidate gene ERBB3 and schizophrenia in Caucasian populationQ51920723
Evidence for transmission disequilibrium at the DAOA gene locus in a schizophrenia family sample.Q54475660
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Mutation screening of theDTNBP1exonic sequence in 669 schizophrenics and 710 controls using high-resolution melting analysisQ58462510
Support for NRG1 as a Susceptibility Factor for Schizophrenia in a Northern Swedish Isolated PopulationQ59698060
G72/G30(DAOA) and juvenile-onset mood disordersQ61570663
Isolation, sequence and genotyping of the drug metabolizer CYP2D6 gene in the Colombian populationQ73731439
Association study between the cholecystokinin A receptor gene and schizophrenia in the Japanese populationQ80109313
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Pharmacogenomic protocols in CNS disorders and dementiaQ83106914
Association between golli-MBP and schizophrenia in the Jewish Ashkenazi population: are regulatory regions involved?Q83205540
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Association analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese populationQ30856619
Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpointQ30884325
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Analysis of flavin-containing monooxygenase 3 genotype data in populations administered the anti-schizophrenia agent olanzapineQ33428292
BDNF is not associated with schizophrenia: data from a Japanese population study and meta-analysisQ33437356
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cellsQ33498169
Apoptotic engulfment pathway and schizophreniaQ33498943
Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjectsQ33503890
Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sampleQ33554950
Familial aggregation of clinical and neurocognitive features in sibling pairs with and without schizophreniaQ33619294
Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.Q33630685
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophreniaQ33727503
Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorderQ33793694
The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variationQ33802672
DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical culturesQ33820124
Pharmacogenetics of psychotropic drug responseQ33977981
A hotspot of inactivation: The A22S and V108M polymorphisms individually destabilize the active site structure of catechol O-methyltransferaseQ34005767
Variable number of tandem repeat polymorphisms of DRD4: re-evaluation of selection hypothesis and analysis of association with schizophreniaQ34161627
PM frequencies of major CYPs in Asians and CaucasiansQ34228441
G72/G30 in schizophrenia and bipolar disorder: review and meta-analysisQ34508029
Reelin down-regulation in mice and psychosis endophenotypesQ34537189
An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes.Q34541215
Cytochrome P450 polymorphisms and response to antipsychotic therapy.Q34612118
Reduced occipital and prefrontal brain volumes in dysbindin-associated schizophreniaQ34660717
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Association between polymorphisms in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) on chromosome 8p and schizophreniaQ34775416
Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based studyQ34923924
Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophreniaQ34926937
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE).Q34946927
Neural mechanisms of a genome-wide supported psychosis variantQ34978645
Pharmacogenomics for the treatment of dementiaQ35009345
Brain cannabinoid CB2 receptor in schizophreniaQ35014134
A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depressionQ35014891
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Pharmacogenetics and drug development: the path to safer and more effective drugsQ35889605
Ethnic differences in genetic polymorphisms of CYP2D6, CYP2C19, CYP3As and MDR1/ABCB1.Q35925154
Pharmacogenomics and therapeutic prospects in Alzheimer's diseaseQ36273420
Structural variation of the human genomeQ36509260
The neurobiology of cognition in schizophrenia.Q36590627
Molecular genetics of bipolar disorder and depression.Q36713347
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Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophreniaQ36886717
Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).Q36896721
Pharmacogenetics and schizophreniaQ36919294
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Genomics and the future of pharmacotherapy in psychiatryQ36951758
Molecular differentiation of schizoaffective disorder from schizophrenia using BDNF haplotypesQ37149314
Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnessesQ37226971
Transcriptional interaction of an estrogen receptor splice variant and ErbB4 suggests convergence in gene susceptibility pathways in schizophreniaQ37254085
Epistasis between the DAT 3' UTR VNTR and the COMT Val158Met SNP on cortical function in healthy subjects and patients with schizophreniaQ37304041
The future (or lack of future) of personalized prescription in psychiatry.Q37321466
A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophreniaQ37354799
Association of the 5'-upstream regulatory region of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) with schizophreniaQ37356715
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophreniaQ37372778
Oestrogen--a new treatment approach for schizophrenia?Q37394122
Positive and negative symptoms in schizophrenia: the NMDA receptor hypofunction hypothesis, neuregulin/ErbB4 and synapse regressionQ37560810
Family-based association of YWHAH in psychotic bipolar disorderQ37570066
Pharmacogenomics and therapeutic strategies for dementiaQ37592250
The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review and economic evaluationQ37661688
Transporter associated with antigen processing and the chaperone tapasin: are non-classical HLA genes keys to the pathogenesis of schizophrenia?Q37855507
Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophreniaQ38380457
Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophreniaQ39861509
Differential effects of aripiprazole and haloperidol on BDNF-mediated signal changes in SH-SY5Y cellsQ39886992
A two-method meta-analysis of Neuregulin 1(NRG1) association and heterogeneity in schizophreniaQ39988164
Molecular genetics of Alzheimer's disease and agingQ40351678
Upregulation of NRG-1 and VAMP-1 in human brain aggregates exposed to clozapineQ42580467
Dopaminergic pathway gene polymorphisms and genetic susceptibility to schizophrenia among north Indians.Q43218140
P433issue5
P921main subjectschizophreniaQ41112
genomicsQ222046
pharmacogenomicsQ1152227
P1104number of pages25
P304page(s)541-565
P577publication date2010-08-16
P1433published inCNS Neuroscience & TherapeuticsQ5013184
P1476titleGenomics and pharmacogenomics of schizophrenia
P478volume17

Reverse relations

cites work (P2860)
Q37930029Epidemiology and Risk Factors for (Tardive) Dyskinesia
Q92986591Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2
Q85263415Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics
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Q33581609Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Q38003392Pharmacogenetics: a reality or misplaced optimism?
Q58781437Usefulness of Pharmacogenetic Analysis in Psychiatric Clinical Practice: A Case Report

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