scholarly article | Q13442814 |
P356 | DOI | 10.1038/NRI2818 |
P953 | full work available at URL | http://www.nature.com/articles/nri2818 |
http://www.nature.com/articles/nri2818.pdf | ||
P698 | PubMed publication ID | 20725108 |
P5875 | ResearchGate publication ID | 45721450 |
P50 | author | Anjana Rao | Q85941651 |
P2093 | author name string | Martin R. Müller | |
P2860 | cites work | Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? | Q83125659 |
Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy | Q84207047 | ||
Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity | Q22008847 | ||
NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun | Q22010152 | ||
Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress | Q24291525 | ||
FOXP3 controls regulatory T cell function through cooperation with NFAT | Q24298179 | ||
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT | Q24306261 | ||
Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3 | Q24309262 | ||
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins | Q24310048 | ||
Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins | Q24317724 | ||
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression | Q24622498 | ||
FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1 | Q24641842 | ||
The epithelial-mesenchymal transition generates cells with properties of stem cells | Q24650786 | ||
Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1 | Q24654657 | ||
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells | Q24655751 | ||
NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins | Q27649708 | ||
NF-AT components define a family of transcription factors targeted in T-cell activation | Q28114991 | ||
Requirement for RORgamma in thymocyte survival and lymphoid organ development | Q28139666 | ||
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature | Q28204868 | ||
The role of NFAT transcription factors in integrin-mediated carcinoma invasion | Q28206477 | ||
NFAT proteins: key regulators of T-cell development and function | Q28253919 | ||
The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun | Q28263918 | ||
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT | Q28270512 | ||
Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway | Q28274746 | ||
The biology of NKT cells | Q28277482 | ||
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes | Q28277749 | ||
Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT | Q28283545 | ||
The calcineurin phosphatase complex modulates immunogenic B cell responses | Q28296946 | ||
NFATc2-mediated repression of cyclin-dependent kinase 4 expression | Q28505899 | ||
Normal B-1a cell development requires B cell-intrinsic NFATc1 activity | Q28509932 | ||
NFATc1 balances quiescence and proliferation of skin stem cells | Q28511548 | ||
Isolation of the cyclosporin-sensitive T cell transcription factor NFATp | Q28511815 | ||
Regulation of the NFAT pathway discriminates CD4+CD25+ regulatory T cells from CD4+CD25- helper T cells. | Q42521715 | ||
Constitutive NF-kappaB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas | Q42741779 | ||
Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis | Q44066637 | ||
NF-ATc2 induces apoptosis in Burkitt's lymphoma cells through signaling via the B cell antigen receptor | Q44321045 | ||
A new cell-permeable peptide allows successful allogeneic islet transplantation in mice | Q44760624 | ||
Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells | Q45345622 | ||
Calcineurin/NFAT signaling in osteoblasts regulates bone mass | Q46675973 | ||
Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells. | Q46851148 | ||
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A | Q46979889 | ||
Role of NFAT proteins in IL13 gene transcription in mast cells | Q47260082 | ||
The NFAT1 transcription factor is a repressor of cyclin A2 gene expression. | Q51796031 | ||
Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. | Q54113549 | ||
Nuclear factor of activated T cells contains Fos and Jun. | Q54271859 | ||
CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation | Q58883568 | ||
Linking calcineurin activity to leukemogenesis | Q80442223 | ||
Expression analysis of nuclear factor of activated T cells (NFAT) during myeloid differentiation of CD34+ cells: regulation of Fas ligand gene expression in megakaryocytes | Q80497569 | ||
Transcriptional partners in regulatory T cells: Foxp3, Runx and NFAT | Q80586216 | ||
The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas | Q81311937 | ||
Calcium signalling in lymphocyte activation and disease | Q36912139 | ||
Selective role of calcineurin in haematopoiesis and lymphopoiesis | Q36969291 | ||
Dual roles for NFAT transcription factor genes as oncogenes and tumor suppressors. | Q36994797 | ||
Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma | Q36995485 | ||
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation | Q37065897 | ||
Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cells | Q37072458 | ||
Akt/protein kinase b and glycogen synthase kinase-3beta signaling pathway regulates cell migration through the NFAT1 transcription factor. | Q37155812 | ||
Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development | Q37182722 | ||
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells | Q37310026 | ||
Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase | Q37399188 | ||
Regulation of T-cell tolerance by calcium/NFAT signaling | Q37597631 | ||
Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation | Q37597633 | ||
Interaction of calcineurin with substrates and targeting proteins | Q37813260 | ||
Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells | Q38326221 | ||
NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells | Q39777198 | ||
NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma. | Q39805013 | ||
MHC class II molecules activate NFAT and the ERK group of MAPK through distinct signaling pathways in B cells | Q39835067 | ||
HIF-1alpha is up-regulated in activated mast cells by a process that involves calcineurin and NFAT. | Q39959183 | ||
TRPV6 channel controls prostate cancer cell proliferation via Ca(2+)/NFAT-dependent pathways. | Q40126939 | ||
Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia | Q40130034 | ||
The B cell antigen receptor controls AP-1 and NFAT activity through Ras-mediated activation of Ral. | Q40181180 | ||
Specific and redundant roles for NFAT transcription factors in the expression of mast cell-derived cytokines. | Q40212619 | ||
Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway | Q40250435 | ||
Identification of common transcriptional regulatory elements in interleukin-17 target genes | Q40263019 | ||
NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2. | Q40310709 | ||
Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3. | Q40321353 | ||
Constitutive NF-kappaB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival | Q40385482 | ||
Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1. | Q40561279 | ||
A constitutively active NFATc1 mutant induces a transformed phenotype in 3T3-L1 fibroblasts | Q40669040 | ||
A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1. | Q40815624 | ||
Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling | Q41825111 | ||
Requirement for IL-13 independently of IL-4 in experimental asthma | Q41881960 | ||
NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells | Q41938630 | ||
SnapShot: Ca2+-calcineurin-NFAT signaling | Q42163961 | ||
Regulation of the murine Nfatc1 gene by NFATc2. | Q42515564 | ||
NFATc1 regulates lymphatic endothelial development | Q28593523 | ||
Transcriptional regulation by calcium, calcineurin, and NFAT | Q29620410 | ||
Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT | Q30157087 | ||
Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase | Q30486988 | ||
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. | Q30778570 | ||
Interleukin-11 in endometrial adenocarcinoma is regulated by prostaglandin F2alpha-F-prostanoid receptor interaction via the calcium-calcineurin-nuclear factor of activated T cells pathway and negatively regulated by the regulator of calcineurin-1. | Q33556402 | ||
Prostaglandin F(2alpha)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium-calcineurin-NFAT pathway | Q33590672 | ||
A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo. | Q33677482 | ||
Molecular basis of calcium signaling in lymphocytes: STIM and ORAI | Q33819323 | ||
NFAT proteins: emerging roles in cancer progression | Q33837647 | ||
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate | Q33908130 | ||
Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl. | Q33996893 | ||
The E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation. | Q34041946 | ||
Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis | Q34093829 | ||
Transcriptional mechanisms underlying lymphocyte tolerance. | Q34135663 | ||
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases | Q34148745 | ||
Identification of a putative regulator of early T cell activation genes | Q34171263 | ||
Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules | Q34335785 | ||
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. | Q34504363 | ||
Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function | Q34567627 | ||
Control of regulatory T cell lineage commitment and maintenance | Q34658594 | ||
VEGF-A and the induction of pathological angiogenesis | Q34718259 | ||
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer | Q34729938 | ||
Transcriptional complexes formed by NFAT dimers regulate the induction of T cell tolerance | Q34967371 | ||
A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus | Q35847639 | ||
Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo | Q36246828 | ||
Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2 | Q36369190 | ||
Discovery of vascular permeability factor (VPF). | Q36375479 | ||
NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells | Q36491849 | ||
Nuclear factor of activated T cells (NFAT) mediates CD154 expression in megakaryocytes | Q36508895 | ||
Regulation of transcription factor NFAT by ADP-ribosylation | Q36540217 | ||
B-1 B cell development | Q36571904 | ||
The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. | Q36804149 | ||
Contribution of platelet-derived CD40 ligand to inflammation, thrombosis and neoangiogenesis. | Q36907331 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 645-656 | |
P577 | publication date | 2010-08-20 | |
P1433 | published in | Nature Reviews Immunology | Q43355 |
P1476 | title | NFAT, immunity and cancer: a transcription factor comes of age | |
P478 | volume | 10 |
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Q50279033 | A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer |
Q55457272 | Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+-NFAT signaling. |
Q37164683 | Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms |
Q48197344 | Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma. |
Q33771022 | All-optical regulation of gene expression in targeted cells |
Q30596522 | Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome. |
Q64060187 | An Optogenetic Controllable T Cell System for Hepatocellular Carcinoma Immunotherapy |
Q90414603 | Analysis of NFATc1 amplification in T cells for pharmacodynamic monitoring of tacrolimus in kidney transplant recipients |
Q37493426 | Atypical behavior of NFATc1 in cultured intercostal myofibers |
Q58483027 | Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy |
Q90841499 | Biology and regulation of IL-2: from molecular mechanisms to human therapy |
Q89296972 | Biomarkers for individualized dosage adjustments in immunosuppressive therapy using calcineurin inhibitors after organ transplantation |
Q36580410 | Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation |
Q39274384 | Bridging topological and functional information in protein interaction networks by short loops profiling |
Q35097318 | CCAAT enhancer binding protein and nuclear factor of activated T cells regulate HIV-1 LTR via a novel conserved downstream site in cells of the monocyte-macrophage lineage |
Q35599091 | Calcineurin mediates the gonadotropin-releasing hormone effect on expression of both subunits of the follicle-stimulating hormone through distinct mechanisms |
Q26866022 | Calcineurin-Crz1 signaling in lower eukaryotes |
Q38729042 | Calcineurin-NFAT signalling in myeloid leucocytes: new prospects and pitfalls in immunosuppressive therapy. |
Q43141087 | Calcineurin/CXCR4 in T-ALL. |
Q39327022 | Calcineurin/NFATc1 pathway contributes to cell proliferation in hepatocellular carcinoma |
Q35035572 | Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV |
Q34543426 | Calcyclin-binding protein/Siah-1-interacting protein as a regulator of transcriptional responses in brain cells |
Q42728732 | Cell cycle arrest caused by MEK/ERK signaling is a mechanism for suppressing growth of antigen-hyperstimulated effector T cells |
Q90351424 | Characterization of the effects of immunomodulatory drug fingolimod (FTY720) on human T cell receptor signaling pathways |
Q36217268 | Cited2 gene controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4 gene |
Q38953475 | Combination therapy for KIT-mutant mast cells: targeting constitutive NFAT and KIT activity. |
Q39314141 | Constitutive calcium entry and cancer: updated views and insights. |
Q38730315 | Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca2+ Signals |
Q34924151 | Control of neuronal apoptosis by reciprocal regulation of NFATc3 and Trim17 |
Q92134153 | Coupled feedback regulation of nuclear factor of activated T-cells (NFAT) modulates activation-induced cell death of T cells |
Q42145722 | Curcumin suppresses T cell activation by blocking Ca2+ mobilization and nuclear factor of activated T cells (NFAT) activation |
Q38439600 | Cutting Edge: NFAT Transcription Factors Promote the Generation of Follicular Helper T Cells in Response to Acute Viral Infection |
Q36426504 | Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway. |
Q38919313 | Cyclosporine A and tacrolimus inhibit urothelial tumorigenesis |
Q41665058 | DNA methylation profiling in human lung tissue identifies genes associated with COPD. |
Q40150881 | DNA methylation signatures and coagulation factors in the peripheral blood leucocytes of epithelial ovarian cancer |
Q41580184 | DYRK1A in Down syndrome: an oncogene or tumor suppressor? |
Q38866748 | DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis |
Q55669579 | Dendritic Cells in the Cross Hair for the Generation of Tailored Vaccines. |
Q34105197 | Differentially expressed genes and interacting pathways in bladder cancer revealed by bioinformatic analysis |
Q39847481 | Distinct spatial Ca2+ signatures selectively activate different NFAT transcription factor isoforms |
Q96118495 | Distribution of ACE2, CD147, CD26 and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors |
Q62658486 | Don't move: LRRK2 arrests NFAT in the cytoplasm |
Q92118481 | Dose-Dependent Sorafenib-Induced Immunosuppression Is Associated with Aberrant NFAT Activation and Expression of PD-1 in T Cells |
Q24302553 | Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor |
Q38987117 | Dynamic assembly of a membrane signaling complex enables selective activation of NFAT by Orai1. |
Q37218781 | Early growth response 3 (Egr-3) is induced by transforming growth factor-β and regulates fibrogenic responses |
Q38091213 | Emerging roles of store-operated Ca²⁺ entry through STIM and ORAI proteins in immunity, hemostasis and cancer |
Q35531181 | Emerging theme: cellular PDZ proteins as common targets of pathogenic viruses |
Q36481790 | Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact |
Q92642755 | Endothelial Ca2+ Signaling, Angiogenesis and Vasculogenesis: just What It Takes to Make a Blood Vessel |
Q54978413 | EphA2 stimulates VCAM-1 expression through calcium-dependent NFAT1 activity. |
Q37204039 | Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter |
Q34387784 | Evidence for the importance of personalized molecular profiling in pancreatic cancer |
Q52746431 | Experimental Therapy of Advanced Breast Cancer: Targeting NFAT1-MDM2-p53 Pathway. |
Q34029073 | Extracellular ATP activates NFAT-dependent gene expression in neuronal PC12 cells via P2X receptors |
Q38730495 | FOXP1 enhances tumor cell migration by repression of NFAT1 transcriptional activity in MDA-MB-231 cells |
Q39483793 | Fever-like temperature modification differentially affects in vitro signaling of bradykinin B(1) and B(2) receptors |
Q37630206 | Follicular regulatory T cells control humoral autoimmunity via NFAT2-regulated CXCR5 expression |
Q100525938 | Formaldehyde exposure induces regulatory T cell-mediated immunosuppression via calcineurin-NFAT signalling pathway |
Q48309565 | From phagocytosis to metaforosis: Calcineurin's deadly role in innate processing of fungi. |
Q34118885 | Function of a Foxp3 cis-element in protecting regulatory T cell identity |
Q38881719 | Galanin modulates the neural niche to favour perineural invasion in head and neck cancer. |
Q58612325 | Genetic variation determines VEGF-A plasma levels in cancer patients |
Q37321175 | Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells |
Q38024850 | Gonadotrophin-releasing hormone signalling downstream of calmodulin |
Q47155594 | Gα13 ablation reprograms myofibers to oxidative phenotype and enhances whole-body metabolism |
Q28545016 | Herpesviral G protein-coupled receptors activate NFAT to induce tumor formation via inhibiting the SERCA calcium ATPase |
Q91686301 | HuR controls apoptosis and activation response without effects on cytokine 3' UTRs |
Q24302043 | Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2 |
Q33849531 | Hypothermia Promotes Interleukin-22 Expression and Fine-Tunes Its Biological Activity. |
Q35713259 | IQGAP1 and its binding proteins control diverse biological functions |
Q35132297 | IQGAPs choreograph cellular signaling from the membrane to the nucleus |
Q34711442 | Identification and evolution of an NFAT gene involving Branchiostoma belcheri innate immunity |
Q45266653 | Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells |
Q91827368 | Identification of Targetable Pathways in Oral Cancer Patients via Random Forest and Chemical Informatics |
Q37020608 | Illuminating Cell Signaling with Near-Infrared Light-Responsive Nanomaterials |
Q42181842 | Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4. |
Q47569148 | Immunological Disorders: Regulation of Ca2+ Signaling in T Lymphocytes |
Q98386333 | Implications of lipid droplets in lung cancer: Associations with drug resistance |
Q38601650 | Increased adaptive immune responses and proper feedback regulation protect against clinical dengue. |
Q37424693 | Increased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells |
Q36958621 | Increased expression of nuclear factor of activated T cells 1 drives IL-9-mediated allergic asthma. |
Q39143922 | Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization. |
Q36545083 | Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapA |
Q38966105 | Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein |
Q45772566 | Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness. |
Q33945848 | Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma |
Q36723728 | Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy |
Q42203363 | Interleukin-2 production by dendritic cells and its immuno-regulatory functions |
Q39272758 | Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity |
Q34182054 | Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). |
Q52596229 | Ion channelopathies of the immune system. |
Q37626165 | IκB Kinase ε Is an NFATc1 Kinase that Inhibits T Cell Immune Response |
Q31153200 | Key Genes in Stomach Adenocarcinoma Identified via Network Analysis of RNA-Seq Data |
Q91776030 | Landscape of innate immune system transcriptome and acute T cell-mediated rejection of human kidney allografts |
Q50978065 | Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemia. |
Q36156814 | Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis |
Q36891490 | Mechanisms and Disease Associations of Haplotype-Dependent Allele-Specific DNA Methylation |
Q35763089 | Mechanisms of rapid induction of interleukin-22 in activated T cells and its modulation by cyclosporin a. |
Q64283715 | MiR-30 family prevents uPAR-ITGB3 signaling activation through calcineurin-NFATC pathway to protect podocytes |
Q34818972 | MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells |
Q93090675 | Modular Antigen-Specific T-cell Biofactories for Calibrated In Vivo Synthesis of Engineered Proteins |
Q91705552 | Modulation of TCR-dependent NFAT signaling is impaired in HIV-1 Nef isolates from elite controllers |
Q36455193 | NFAT as cancer target: mission possible? |
Q52641496 | NFAT control of immune function: New Frontiers for an Abiding Trooper. |
Q36865831 | NFAT restricts osteochondroma formation from entheseal progenitors |
Q36846004 | NFAT signaling in osteoblasts regulates the hematopoietic niche in the bone microenvironment |
Q34460667 | NFAT1 C-terminal domains are necessary but not sufficient for inducing cell death |
Q36963684 | NFAT1 Directly Regulates IL8 and MMP3 to Promote Melanoma Tumor Growth and Metastasis. |
Q47709729 | NFAT1 Regulates Systemic Autoimmunity through the Modulation of a Dendritic Cell Property. |
Q64266491 | NFAT1 and NFAT2 Differentially Regulate CTL Differentiation Upon Acute Viral Infection |
Q60315851 | NFAT1 deficit and NFAT2 deficit attenuate EAE via different mechanisms |
Q34770388 | NFAT1 is highly expressed in, and regulates the invasion of, glioblastoma multiforme cells |
Q35630191 | NFAT1 promotes intratumoral neutrophil infiltration by regulating IL8 expression in breast cancer |
Q47093820 | NFAT1-regulated IL6 signalling contributes to aggressive phenotypes of glioma |
Q41819322 | NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia |
Q36985073 | NFAT5 represses canonical Wnt signaling via inhibition of β-catenin acetylation and participates in regulating intestinal cell differentiation. |
Q34019182 | NFAT5-mediated expression of S100A4 contributes to proliferation and migration of renal carcinoma cells |
Q58565380 | NFATC2 is a novel therapeutic target for colorectal cancer stem cells |
Q38290269 | NFATC3 promotes IRF7 transcriptional activity in plasmacy--toid dendritic cells. |
Q38916311 | NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas. |
Q37377454 | NFATc1 and NFATc2 repress spontaneous osteoarthritis |
Q40937224 | NFATc1 as a therapeutic target in FLT3-ITD-positive AML. |
Q53622887 | NFATc1 deletion in T lymphocytes inhibits the allergic trait in a murine model of asthma. |
Q58796653 | NFATc1 is a tumor suppressor in hepatocellular carcinoma and induces tumor cell apoptosis by activating the FasL-mediated extrinsic signaling pathway |
Q40885164 | NFATc1 releases BCL6-dependent repression of CCR2 agonist expression in peritoneal macrophages from Saccharomyces cerevisiae infected mice. |
Q39591211 | NFATc1/αA: The other Face of NFAT Factors in Lymphocytes |
Q38924304 | NFATc2 mediates epigenetic modification of dendritic cell cytokine and chemokine responses to dectin-1 stimulation. |
Q41592878 | NFATc3 mediates the sensitivity of gastric cancer cells to arsenic sulfide |
Q28484467 | Natalizumab exerts direct signaling capacity and supports a pro-inflammatory phenotype in some patients with multiple sclerosis |
Q36533981 | Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation |
Q34467607 | Nerve growth factor (NGF) regulates activity of nuclear factor of activated T-cells (NFAT) in neurons via the phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3β (GSK3β) pathway |
Q31030029 | Newly Constructed Network Models of Different WNT Signaling Cascades Applied to Breast Cancer Expression Data |
Q33779715 | Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis |
Q36542874 | Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes |
Q35000337 | Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis |
Q36508744 | Nuclear factor of activated T-cells (NFAT)C2 inhibits Notch receptor signaling in osteoblasts |
Q91735303 | Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML |
Q36516948 | Oncogenic transcription factors: cornerstones of inflammation-linked pancreatic carcinogenesis |
Q37462378 | Orai1-NFAT signalling pathway triggered by T cell receptor stimulation |
Q38441750 | Overcoming intrinsic inhibitory pathways to augment the antineoplastic activity of adoptively transferred T cells: Re-tuning your CAR before hitting a rocky road |
Q92799403 | P2X7 Interactions and Signaling - Making Head or Tail of It |
Q38987628 | P2Y12 receptors in primary microglia activate nuclear factor of activated T-cell signaling to induce C-C chemokine 3 expression |
Q35018554 | PMA and ionomycin induce glioblastoma cell death: activation-induced cell-death-like phenomena occur in glioma cells |
Q55467557 | PathCORE-T: identifying and visualizing globally co-occurring pathways in large transcriptomic compendia. |
Q38560506 | Pathogenesis and targeted treatment of skin injury in SLE. |
Q49722278 | Pathogenesis of Skin Injury of Systemic Lupus Erythematosus |
Q39302141 | Paxillin phosphorylation by JNK and p38 is required for NFAT activation |
Q48006409 | Peptides derived from transcription factor EB bind to calcineurin at a similar region as the NFAT-type motif |
Q35192436 | Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus |
Q37504288 | Phospho-sulindac inhibits pancreatic cancer growth: NFATc1 as a drug resistance candidate |
Q37019248 | Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue |
Q35034012 | Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes |
Q39417313 | Phosphoproteomics analyses show subnetwork systems in T-cell receptor signaling. |
Q42061814 | Placing ion channels into a signaling network of T cells: from maturing thymocytes to healthy T lymphocytes or leukemic T lymphoblasts. |
Q38928538 | Primate Lentiviruses Modulate NF-κB Activity by Multiple Mechanisms to Fine-Tune Viral and Cellular Gene Expression |
Q40123168 | Profiling of cellular microRNA responses during the early stages of KSHV infection. |
Q37480216 | Quercetin targets the interaction of calcineurin with LxVP-type motifs in immunosuppression. |
Q94503527 | Receptor signaling, transcriptional, and metabolic regulation of T cell exhaustion |
Q91874206 | Redox signals at the ER-mitochondria interface control melanoma progression |
Q38019405 | Regulation and dysregulation of innate immunity by NFAT signaling downstream of pattern recognition receptors (PRRs). |
Q38147883 | Regulatory mechanisms that control T-follicular helper and T-helper 1 cell flexibility |
Q35979299 | Resistance to ABT-737 in activated T lymphocytes: molecular mechanisms and reversibility by inhibition of the calcineurin-NFAT pathway |
Q36766325 | Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer |
Q38586690 | Role of Calcium Signaling in B Cell Activation and Biology |
Q38572497 | Role of Ets Proteins in Development, Differentiation, and Function of T-Cell Subsets |
Q36946379 | Role of diacylglycerol kinases in T cell development and function |
Q41910430 | Role of nuclear factor of activated T cells 1 in the pathogenesis of osteoarthritis |
Q39072230 | Roles of IκB kinase ε in the innate immune defense and beyond. |
Q42778064 | SCENIC: single-cell regulatory network inference and clustering. |
Q26781966 | SOCE and cancer: Recent progress and new perspectives |
Q89636821 | STAT3 activates MSK1-mediated histone H3 phosphorylation to promote NFAT signaling in gastric carcinogenesis |
Q35037993 | Selective NFAT targeting in T cells ameliorates GvHD while maintaining antitumor activity |
Q34230563 | Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6. |
Q38511575 | Signaling in lymphocyte activation |
Q41995058 | Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems. |
Q47165489 | Src-family kinases negatively regulate NFAT signaling in resting human T cells. |
Q37029755 | Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity |
Q47655605 | Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming. |
Q34355882 | Stromal interaction molecule 1 (STIM1) and Orai1 mediate histamine-evoked calcium entry and nuclear factor of activated T-cells (NFAT) signaling in human umbilical vein endothelial cells. |
Q26781513 | Structural Basis of Targeting the Exportin CRM1 in Cancer |
Q36483189 | Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways |
Q36754365 | TNFR-associated factor 6 regulates TCR signaling via interaction with and modification of LAT adapter |
Q38780085 | TPL2 Kinase Is a Crucial Signaling Factor and Mediator of NKT Effector Cytokine Expression in Immune-Mediated Liver Injury |
Q59136425 | Targeting Anion Exchange of Osteoclast, a New Strategy for Preventing Wear Particles Induced- Osteolysis |
Q64253749 | Targeting Tyrosine kinases in Renal Cell Carcinoma: "New Bullets against Old Guys" |
Q33804696 | Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors. |
Q36956985 | The DNA methylation profile of activated human natural killer cells. |
Q38839497 | The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells. |
Q36436005 | The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses |
Q92327821 | The Puzzling Role of Neuron-Specific PMCA Isoforms in the Aging Process |
Q36779438 | The calcineurin-NFAT pathway negatively regulates megakaryopoiesis |
Q27330253 | The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells. |
Q47122756 | The cargo protein MAP17 (PDZK1IP1) regulates the immune microenvironment |
Q50636803 | The cooperation of CREB and NFAT is required for PTHrP-induced RANKL expression in mouse osteoblastic cells. |
Q28256143 | The short-chain fatty acid receptor GPR43 is transcriptionally regulated by XBP1 in human monocytes |
Q42218721 | The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells |
Q28068998 | Therapeutic potential of targeting acinar cell reprogramming in pancreatic cancer |
Q36216395 | Transcription factor NFAT1 activates the mdm2 oncogene independent of p53. |
Q36500059 | Transcription factor NFAT1 controls allergic contact hypersensitivity through regulation of activation induced cell death program. |
Q41592849 | Transcription factor c-Rel is indispensable for generation of thymic but not of peripheral Foxp3+ regulatory T cells |
Q37662252 | Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy. |
Q24338120 | USP22 is a positive regulator of NFATc2 on promoting IL2 expression |
Q38212817 | Unconventional post-translational modifications in immunological signaling |
Q92757526 | Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 |
Q38000118 | Unraveling STIM2 function |
Q36884697 | Up-regulation of Store-operated Ca2+ Entry and Nuclear Factor of Activated T Cells Promote the Acinar Phenotype of the Primary Human Salivary Gland Cells |
Q59336036 | Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness |
Q42152602 | Using machine learning algorithms to identify genes essential for cell survival |
Q26851822 | Vesicular trafficking and signaling for cytokine and chemokine secretion in mast cells |
Q40623679 | Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection |
Q33833563 | Vitamin D in inflammatory diseases |
Q36639258 | Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer's disease |
Q38035203 | Waking up the sleepers: shared transcriptional pathways in axonal regeneration and neurogenesis. |
Q39445406 | Wnt signaling in cardiovascular disease: opportunities and challenges |
Q52804976 | c-Maf controls immune responses by regulating disease-specific gene networks and repressing IL-2 in CD4+ T cells. |
Q64068287 | miR-194 suppresses high glucose-induced non-small cell lung cancer cell progression by targeting NFAT5 |
Q41390605 | miR-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B. |
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