Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation

scientific article published on 25 January 2013

Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI65647
P932PMC publication ID3561818
P698PubMed publication ID23348743
P5875ResearchGate publication ID235371135

P50authorSteven R HouserQ91937861
Jonathan SoboloffQ37381829
P2093author name stringHong Wang
Hui Gao
Donald L Gill
Muniswamy Madesh
Walter J Koch
Ju Chen
Xiao-Feng Yang
Shu Meng
Karthik Mallilankaraman
Rajesh Kumar Gandhirajan
Salvatore Mancarella
Harish C Chandramoorthy
Roshanak Razmpour
P2860cites workPOST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transportersQ24297371
STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influxQ24307461
A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cellsQ24307821
SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refillingQ24310505
CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entryQ24322017
Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)Q24322166
Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activityQ24548526
STIM proteins: dynamic calcium signal transducersQ24633618
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and toleranceQ24642248
STIM1, an essential and conserved component of store-operated Ca2+ channel functionQ24678317
Cell migration: integrating signals from front to backQ27860670
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of careQ27860820
Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa BQ28118928
STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channelsQ28257477
STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell deathQ28261981
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel functionQ28305026
Calcium signalling: dynamics, homeostasis and remodellingQ29547635
The epidemiology of sepsis in the United States from 1979 through 2000Q29547760
Calcium oscillations increase the efficiency and specificity of gene expressionQ29614728
Calcium signalingQ29617338
The pathophysiology and treatment of sepsisQ29619103
The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarctionQ30482557
TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in miceQ30490532
A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity.Q40330987
A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2.Q40472316
Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expressionQ40739475
NADPH oxidase 4 promotes endothelial angiogenesis through endothelial nitric oxide synthase activationQ41554019
G protein-coupled receptor Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/leukocyte adherenceQ42910631
Critical role of NADPH oxidase-derived reactive oxygen species in generating Ca2+ oscillations in human aortic endothelial cells stimulated by histamine.Q44047551
Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2.Q44725330
Early lipopolysaccharide-induced reactive oxygen species production evokes necrotic cell death in human umbilical vein endothelial cellsQ46077896
Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivoQ46365897
Lipopolysaccharide activated phosphatidylcholine-specific phospholipase C and induced IL-8 and MCP-1 production in vascular endothelial cellsQ46463936
Ca2+ oscillation frequency regulates agonist-stimulated gene expression in vascular endothelial cellsQ46483101
The calcium sensors STIM1 and STIM2 control B cell regulatory function through interleukin-10 productionQ46938631
Mechanisms of endothelial cell injury in acute inflammation.Q49327064
NADPH oxidase activation increases the sensitivity of intracellular Ca2+ stores to inositol 1,4,5-trisphosphate in human endothelial cellsQ73626262
Thrombin, TNF-alpha, and LPS exert overlapping but nonidentical effects on gene expression in endothelial cells and vascular smooth muscle cellsQ81656160
Genetically encoded fluorescent indicator for intracellular hydrogen peroxideQ82918322
Effect of protein S-glutathionylation on Ca2+ homeostasis in cultured aortic endothelial cellsQ30498230
STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunityQ33384395
Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functionsQ33847729
S-glutathionylation activates STIM1 and alters mitochondrial homeostasis.Q34069961
Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitroQ34125796
Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.Q34216810
Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signalingQ34287962
Calcium oscillationsQ34578002
Lung epithelial fluid transport and the resolution of pulmonary edemaQ34711181
Selective activation of the transcription factor NFAT1 by calcium microdomains near Ca2+ release-activated Ca2+ (CRAC) channelsQ34869427
Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungsQ34890336
Temperature-dependent STIM1 activation induces Ca²+ influx and modulates gene expressionQ34990337
Hypoxia-induced acidosis uncouples the STIM-Orai calcium signaling complexQ35639811
Mechanisms of enhanced lung injury during sepsisQ35786898
Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signalingQ35810708
Endotoxin priming of neutrophils requires endocytosis and NADPH oxidase-dependent endosomal reactive oxygen speciesQ35874515
Visualization of vascular Ca2+ signaling triggered by paracrine derived ROS.Q36015158
Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and endothelial apoptosisQ36321026
Signaling mechanisms regulating endothelial permeabilityQ36350076
Acetylcholine-induced calcium signaling and contraction of airway smooth muscle cells in lung slicesQ36445078
Management of sepsisQ36628061
Sensing cellular stress through STIM proteins.Q36697609
Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharideQ36731779
STIM1 restores coronary endothelial function in type 1 diabetic miceQ36769911
Endothelium as a therapeutic target in sepsisQ36789489
Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activationQ37266304
Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lungQ37327475
Preconditioning of primary human endothelial cells with inflammatory mediators alters the "set point" of the cellQ37735841
NFAT, immunity and cancer: a transcription factor comes of ageQ37781277
Decoding cytosolic Ca2+ oscillationsQ37784580
Redox regulation of calcium ion channels: chemical and physiological aspectsQ37935283
The neutrophil in vascular inflammationQ37953775
Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2.Q39903564
P4510describes a project that usesImageJQ1659584
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectlipopolysaccharideQ421804
P1104number of pages16
P304page(s)887-902
P577publication date2013-01-25
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleBlockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation
P478volume123

Reverse relations

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