| scholarly article | Q13442814 |
| P356 | DOI | 10.1021/JO101124N |
| P953 | full work available at URL | https://europepmc.org/articles/pmc2966535?pdf=render |
| https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20882949/?tool=EBI | ||
| https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20882949/pdf/?tool=EBI | ||
| https://europepmc.org/articles/PMC2966535 | ||
| https://europepmc.org/articles/PMC2966535?pdf=render | ||
| https://doi.org/10.1021/jo101124n | ||
| https://pubs.acs.org/doi/pdf/10.1021/jo101124n | ||
| P932 | PMC publication ID | 2966535 |
| P698 | PubMed publication ID | 20882949 |
| P5875 | ResearchGate publication ID | 47154650 |
| P2093 | author name string | David H. Sherman | |
| Jonathan D. Mortison | |||
| P2860 | cites work | Cancer Research | Q326097 |
| Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria | Q27635569 | ||
| Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: Versatility from a unique substrate channel | Q27636992 | ||
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| Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase | Q44431811 | ||
| Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase | Q44542093 | ||
| Substrate recognition and channeling of monomodules from the pikromycin polyketide synthase | Q44609715 | ||
| A chemoenzymatic approach to glycopeptide antibiotics | Q45126062 | ||
| Biochemical investigation of pikromycin biosynthesis employing native penta- and hexaketide chain elongation intermediates | Q46532515 | ||
| Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide | Q46559470 | ||
| Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis. | Q46565652 | ||
| Chemoenzymatic synthesis of cryptophycin/arenastatin natural products | Q46744925 | ||
| Precursor-directed biosynthesis of epothilone in Escherichia coli | Q46796881 | ||
| Combinatorial polyketide biosynthesis by de novo design and rearrangement of modular polyketide synthase genes. | Q46832912 | ||
| Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae | Q48005296 | ||
| An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea | Q48248704 | ||
| Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae. | Q51192927 | ||
| Synthesis of cryptophycin 52 using the Shi epoxidation. | Q53971574 | ||
| Design, synthesis, and antimicrobial activity of 6-O-substituted ketolides active against resistant respiratory tract pathogens. | Q54057467 | ||
| Analysis of the Molecular Recognition Features of Individual Modules Derived from the Erythromycin Polyketide Synthase | Q60152035 | ||
| Formation of functional heterologous complexes using subunits from the picromycin, erythromycin and oleandomycin polyketide synthases | Q73419416 | ||
| Isolation and structure determination of nostocyclopeptides A1 and A2 from the terrestrial cyanobacterium Nostoc sp. ATCC53789 | Q73423485 | ||
| Dissecting and exploiting intermodular communication in polyketide synthases | Q77330305 | ||
| Phase 2 study of cryptophycin 52 (LY355703) in patients previously treated with platinum based chemotherapy for advanced non-small cell lung cancer | Q78968322 | ||
| Enzymatic release and macrolactonization of cryptophycins from a safety-catch solid support | Q81544564 | ||
| Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase | Q27657793 | ||
| Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase | Q27663333 | ||
| Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase | Q28139333 | ||
| Biomimetic synthesis and optimization of cyclic peptide antibiotics | Q28217202 | ||
| Cryptophycin: a new antimicrotubule agent active against drug-resistant cells | Q28237751 | ||
| Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts | Q28284397 | ||
| The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae | Q30496589 | ||
| Biomimetic Synthesis of Gramicidin S and Analogues by Enzymatic Cyclization of Linear Precursors on Solid Support | Q30791836 | ||
| Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens | Q33179158 | ||
| Chemoenzymatic route to macrocyclic hybrid peptide/polyketide-like molecules. | Q33187336 | ||
| Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412. | Q33279724 | ||
| A multicenter phase II study of the cryptophycin analog LY355703 in patients with platinum-resistant ovarian cancer. | Q33370110 | ||
| In vitro reconstitution of the myxochelin biosynthetic machinery of Stigmatella aurantiaca Sg a15: Biochemical characterization of a reductive release mechanism from nonribosomal peptide synthetases | Q33944320 | ||
| Metamorphic enzyme assembly in polyketide diversification | Q34052844 | ||
| Nonribosomal peptides: from genes to products | Q34209150 | ||
| Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula | Q34343752 | ||
| Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase | Q34346093 | ||
| Polyketide biosynthesis: a millennium review | Q34362914 | ||
| The cryptophycins: their synthesis and anticancer activity | Q34540048 | ||
| Structural basis for macrolactonization by the pikromycin thioesterase | Q34565714 | ||
| Clinical and public health implications of macrolide-resistant Streptococcus pneumoniae. | Q34990169 | ||
| Natural products as sources of new drugs over the period 1981-2002. | Q35184693 | ||
| Macrolactonizations in the total synthesis of natural products | Q36415708 | ||
| An erythromycin analog produced by reprogramming of polyketide synthesis | Q36451359 | ||
| A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity | Q36518025 | ||
| Azalides from azithromycin to new azalide derivatives | Q36786360 | ||
| Reconstitution and characterization of the Escherichia coli enterobactin synthetase from EntB, EntE, and EntF. | Q38339053 | ||
| Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis | Q39641894 | ||
| Analysis of the cryptophycin P450 epoxidase reveals substrate tolerance and cooperativity | Q41438440 | ||
| Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases | Q42019933 | ||
| Modular organization of genes required for complex polyketide biosynthesis | Q42627871 | ||
| Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species | Q42677877 | ||
| Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain | Q43251297 | ||
| Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain from the tyrocidine nonribosomal peptide synthetase | Q43636631 | ||
| Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules | Q43663145 | ||
| Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae | Q43807293 | ||
| Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae | Q43906569 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 7041-7051 | |
| P577 | publication date | 2010-11-01 | |
| 2010-11-05 | |||
| P1433 | published in | Journal of Organic Chemistry | Q898967 |
| P1476 | title | Frontiers and opportunities in chemoenzymatic synthesis | |
| Frontiers and Opportunities in Chemoenzymatic Synthesis | |||
| P478 | volume | 75 |
| Q35871115 | An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer |
| Q42161107 | Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin |
| Q34701607 | Chemoenzymatic synthesis of spinosyn A |
| Q34007283 | Marine natural products: a new wave of drugs? |
| Q37996334 | Merging chemical synthesis and biosynthesis: a new chapter in the total synthesis of natural products and natural product libraries |
| Q35016643 | Multiplexing of combinatorial chemistry in antimycin biosynthesis: expansion of molecular diversity and utility |
| Q44877223 | Oxidation of Pyrrole by Dehaloperoxidase-Hemoglobin: Chemoenzymatic Synthesis of Pyrrolin-2-Ones |
| Q58853556 | Stereoselective Enzymatic Reduction of Ethyl Secodione: Preparation of a Key Intermediate for the Total Synthesis of Steroids |
| Q35612402 | Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases. |
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