Designing polymeric particles for antigen delivery

scientific article

Designing polymeric particles for antigen delivery is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/B914943K
P8608Fatcat IDrelease_pd5bxivukbe6vp6mbvy4yafixq
P698PubMed publication ID21060941
P5875ResearchGate publication ID47718871

P50authorBruno De GeestQ55231999
Bart LambrechtQ18402373
Yvette van KooykQ29914012
P2093author name stringChris Vervaet
Jean Paul Remon
Johan Grooten
Stefaan De Koker
Monique A Willart
P2860cites workPoly(lactic-co-glycolic acid) enhances maturation of human monocyte-derived dendritic cells.Q51615861
Novel Hollow Polymer Shells by Colloid-Templated Assembly of Polyelectrolytes.Q52803764
Surfactant-free anionic PLA nanoparticles coated with HIV-1 p24 protein induced enhanced cellular and humoral immune responses in various animal models.Q53000998
Fuzzy Nanoassemblies: Toward Layered Polymeric MulticompositesQ55966433
Nanoengineering of Inorganic and Hybrid Hollow Spheres by Colloidal TemplatingQ56603709
A Protective Vaccine Delivery System for In Vivo T Cell Stimulation Using Nanoengineered Polymer Hydrogel CapsulesQ56769270
Binding, Internalization, and Antigen Presentation of Vaccine-Loaded Nanoengineered Capsules in BloodQ56769307
A single step process for the synthesis of antigen laden thermosensitive microparticlesQ57366863
Mesoporous Silica Particles as Templates for Preparing Enzyme-Loaded Biocompatible MicrocapsulesQ57645451
NOX2 Controls Phagosomal pH to Regulate Antigen Processing during Crosspresentation by Dendritic CellsQ58007061
Antigen presentation by dendritic cells in vivoQ58757885
Toll-dependent selection of microbial antigens for presentation by dendritic cellsQ59063722
Innate immune recognition: mechanisms and pathwaysQ28138782
Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trialQ28236008
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cellsQ28506676
Phagosomes are competent organelles for antigen cross-presentationQ28591811
Immunobiology of dendritic cellsQ29547465
Differential antigen processing by dendritic cell subsets in vivoQ29615177
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvantsQ29615635
Recognition of microorganisms and activation of the immune responseQ29617903
Biodegradable microcapsules designed via 'click' chemistryQ45413284
Nanoparticles target distinct dendritic cell populations according to their sizeQ45732404
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in miceQ45876568
Towards clinical testing of a single-administration tetanus vaccine based on PLA/PLGA microspheresQ46322113
Injectable dendritic cell-carrying alginate gels for immunization and immunotherapyQ46530740
Spatial and mechanistic separation of cross-presentation and endogenous antigen presentationQ46674193
Encapsulation of the immune potentiators MPL and RC529 in PLG microparticles enhances their potencyQ46856102
Disulfide cross-linked polymer capsules: en route to biodeconstructible systemsQ46883695
Effect of protein molecular weight on release from micron-sized PLGA microspheresQ47201582
Layer-by-layer coating of degradable microgels for pulsed drug delivery.Q49076786
Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigensQ49123460
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomesQ50335815
Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres.Q51253137
Immunological responses after immunisation of mice with microparticles containing antigen and single stranded RNA (polyuridylic acid).Q51323708
Synthesis of protein-loaded hydrogel particles in an aqueous two-phase system for coincident antigen and CpG oligonucleotide delivery to antigen-presenting cells.Q51357882
Directed cell migration via chemoattractants released from degradable microspheres.Q51528715
Protein encapsulation via porous CaCO3 microparticles templatingQ33206684
Activation of dendritic cells by microparticles containing Bacillus anthracis protective antigenQ33215079
Protective immunity of biodegradable nanoparticle-based vaccine against an experimental challenge with Salmonella Enteritidis in mice.Q33282108
Biodegradable nanogels prepared by atom transfer radical polymerization as potential drug delivery carriers: synthesis, biodegradation, in vitro release, and bioconjugationQ33282281
Stabilization of tetanus and diphtheria toxoids against moisture-induced aggregationQ33767232
CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.Q33928441
New advances in microsphere-based single-dose vaccinesQ33933148
Protein release from alginate matricesQ33933226
Poly(lactide-co-glycolide) microparticles for the development of single-dose controlled-release vaccinesQ33933255
Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugatesQ34162875
In vivo targeting of dendritic cells for activation of cellular immunity using vaccine carriers based on pH-responsive microparticlesQ34234901
Sensing pathogens and tuning immune responsesQ34308011
Chitosan as a novel nasal delivery system for vaccinesQ34343257
Pharmacotherapy by intracellular delivery of drugs using fusogenic liposomes: application to vaccine developmentQ34446194
Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factorsQ34588908
Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.Q34623431
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cellsQ34764301
Taking toll: lipid A mimetics as adjuvants and immunomodulatorsQ34960326
Acetalated dextran is a chemically and biologically tunable material for particulate immunotherapyQ34968934
A macromolecular delivery vehicle for protein-based vaccines: acid-degradable protein-loaded microgelsQ34981649
Microparticles as vaccine adjuvants and delivery systemsQ35192199
Recent advances in the discovery and delivery of vaccine adjuvantsQ35209997
Toll-like receptors and acquired immunityQ35642955
Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigensQ35826361
Modulating vaccine responses with dendritic cells and Toll-like receptorsQ35826412
Taking a Toll on human disease: Toll-like receptor 4 agonists as vaccine adjuvants and monotherapeutic agentsQ35842681
Formulation aspects of biodegradable polymeric microspheres for antigen deliveryQ35961150
Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigensQ35961159
Maturation requirements for dendritic cells in T cell stimulation leading to tolerance versus immunityQ36088964
Targeting the innate immune response with improved vaccine adjuvantsQ36090194
Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell toleranceQ36376611
CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunityQ36380885
Translating innate immunity into immunological memory: implications for vaccine developmentQ36404657
Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccinesQ36447615
Expanding the effector CD4 T-cell repertoire: the Th17 lineage.Q36449975
Microparticle-based technologies for vaccinesQ36602257
Targeting dendritic cells with biomaterials: developing the next generation of vaccinesQ36627404
Innate immunity--cross-talk with adaptive immunity through pattern recognition receptors and cytokinesQ36678106
Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigensQ36689895
New hepatitis B vaccine formulated with an improved adjuvant systemQ36780117
Next generation, sequentially assembled ultrathin films: beyond electrostaticsQ36807527
The perfect mix: recent progress in adjuvant researchQ36844715
Toll-like receptor ligands energize peptide vaccines through multiple pathsQ36931433
Recent advances in antigen processing and presentationQ36945533
Vaccine immunopotentiators of the futureQ36959938
Cationic liposomes as vaccine adjuvantsQ36968290
Bridging the knowledge gaps in vaccine designQ37027137
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasomeQ37070610
Endocytosis mechanisms and the cell biology of antigen presentationQ37076774
The cell biology of cross-presentation and the role of dendritic cell subsetsQ37082455
Monocyte-derived dendritic cells in innate and adaptive immunityQ37117563
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cellsQ37139993
The role of phagosomal pH on the size-dependent efficiency of cross-presentation by dendritic cellsQ37327058
Mechanism of action of clinically approved adjuvantsQ37402088
A functional dichotomy in CD4+ T lymphocytesQ39473413
Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.Q39995184
Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunityQ40062912
Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-responsive core-shell nanoparticles.Q40077642
Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticlesQ40327793
Encapsulation of proteins and peptides into biodegradable poly(D,L-lactide-co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cellsQ40351226
Rapid endo-lysosomal escape of poly(DL-lactide-co-glycolide) nanoparticles: implications for drug and gene deliveryQ40713744
Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide)Q42806631
A paradigm for peptide vaccine delivery using viral epitopes encapsulated in degradable polymer hydrogel capsulesQ43466825
Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccinesQ43631849
Antigen co-encapsulated with adjuvants efficiently drive protective T cell immunityQ43883594
Phenotype and functional analysis of human monocyte-derived dendritic cells loaded with biodegradable poly(lactide-co-glycolide) microspheres for immunotherapyQ44032648
A novel strategy for encapsulation and release of proteins: hydrogels and microgels with acid-labile acetal cross-linkersQ44180226
Pulsed in vitro release and in vivo behavior of exploding microcapsulesQ44312979
The preservation of phenotype and functionality of dendritic cells upon phagocytosis of polyelectrolyte-coated PLGA microparticlesQ44467598
Poly(N-(2-hydroxypropyl) methacrylamide mono/di lactate): a new class of biodegradable polymers with tuneable thermosensitivityQ44887736
Targeting dendritic cells with antigen-containing liposomes: a highly effective procedure for induction of antitumor immunity and for tumor immunotherapyQ44942720
TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responsesQ44997831
P433issue1
P304page(s)320-339
P577publication date2010-11-09
P1433published inChemical Society ReviewsQ2962268
P1476titleDesigning polymeric particles for antigen delivery
P478volume40

Reverse relations

cites work (P2860)
Q49131201A Modular Approach To Study Protein Adsorption on Surface Modified Hydroxyapatite
Q58692952A Three Component Synthetic Vaccine Containing a β-Mannan T-Cell Peptide Epitope and a β-Glucan Dendritic Cell Ligand
Q40694699Acid-Labile Thermoresponsive Copolymers That Combine Fast pH-Triggered Hydrolysis and High Stability under Neutral Conditions
Q89983778Advanced biomaterials for cancer immunotherapy
Q36501913An automated two-phase system for hydrogel microbead production.
Q48684399Capturing "Extraordinary" Soft-Assembled Charge-Like Polypeptides as a Strategy for Nanocarrier Design
Q38566314Chitosan-based mucosal adjuvants: Sunrise on the ocean
Q42259049Comparison of PLA microparticles and alum as adjuvants for H5N1 influenza split vaccine: adjuvanticity evaluation and preliminary action mode analysis
Q41654079Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone postmodification
Q38912004Delivery of therapeutics with nanoparticles: what's new in cancer immunotherapy?
Q40101820Direct Loading of iTEP-Delivered CTL Epitope onto MHC Class I Complexes on the Dendritic Cell Surface.
Q57376730Double emulsion template suspension polymerisation: towards the synthesis of polyelectrolyte core porous hydrophobic shell particles for environmental applications
Q57364789Dual pH- and temperature-responsive RAFT-based block co-polymer micelles and polymer–protein conjugates with transient solubility
Q49090708Engineering Polymer Hydrogel Nanoparticles for Lymph Node-Targeted Delivery
Q51005289Mechanically tunable, self-adjuvanting nanoengineered polypeptide particles.
Q42549655Microcapsules functionalized with neuraminidase can enter vascular endothelial cells in vitro
Q38073752Modern subunit vaccines: development, components, and research opportunities
Q35788471Modulating adaptive immune responses to peptide self-assemblies
Q43623067Nanoparticle-based vaccine for mucosal protection against Shigella flexneri in mice
Q42235032Novel vaccine delivery system induces robust humoral and cellular immune responses based on multiple mechanisms
Q38586079Nucleic acid vaccination strategies against infectious diseases.
Q58385253Particulate transepithelial drug carriers: barriers and functional polymers
Q37979152Polymeric multilayer capsules for drug delivery
Q26752054Recent advances of biomaterials in biotherapy
Q38068954Recent progress towards development of a Shigella vaccine
Q36083687Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope
Q36998403Single-dose microparticle delivery of a malaria transmission-blocking vaccine elicits a long-lasting functional antibody response.
Q46930554Spray-dried chitosan microparticles for cellular delivery of an antigenic protein: physico-chemical properties and cellular uptake by dendritic cells and macrophages
Q49030612Surface-engineered polyelectrolyte multilayer capsules: synthetic vaccines mimicking microbial structure and function
Q57644957Targeting Dendritic Cells: The Role of Specific Receptors in the Internalization of Polymer Capsules
Q34532116Targeting human dendritic cells via DEC-205 using PLGA nanoparticles leads to enhanced cross-presentation of a melanoma-associated antigen
Q37484860Thymus transcriptome reveals novel pathways in response to avian pathogenic Escherichia coli infection
Q36512540Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines.
Q95322966Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy

Search more.