Evidence-based mini-review: treatment options for patients with relapsed/refractory myeloma previously treated with novel agents and high-dose chemotherapy and autologous stem-cell transplantation

scientific article published on January 2010

Evidence-based mini-review: treatment options for patients with relapsed/refractory myeloma previously treated with novel agents and high-dose chemotherapy and autologous stem-cell transplantation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1182/ASHEDUCATION-2010.1.310
P932PMC publication ID4086196
P698PubMed publication ID21239811
P5875ResearchGate publication ID49760144

P50authorSagar LonialQ66431075
P2093author name stringNina Shah
P2860cites workImpact of prior therapies on the relative efficacy of bortezomib compared with dexamethasone in patients with relapsed/refractory multiple myelomaQ43281992
Second autologous or allogeneic transplantation after the failure of first autograft in patients with multiple myelomaQ43632773
The role of second autografts in the management of myeloma at first relapse.Q44204181
Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposureQ44620764
The combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesisQ45016242
Toxicity of a second autologous peripheral blood stem cell transplant in patients with relapsed or recurrent multiple myeloma.Q45918038
Bortezomib in combination with pegylated liposomal doxorubicin and thalidomide is an effective steroid independent salvage regimen for patients with relapsed or refractory multiple myeloma: results of a phase II clinical trial.Q45991042
The addition of liposomal doxorubicin to bortezomib, thalidomide and dexamethasone significantly improves clinical outcome of advanced multiple myeloma.Q46646179
Combined pegylated liposomal doxorubicin and bortezomib is highly effective in patients with recurrent or refractory multiple myeloma who received prior thalidomide/lenalidomide therapyQ46733366
Phase I trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) in patients with advanced multiple myelomaQ46735730
Low dose Velcade, thalidomide and dexamethasone (LD-VTD): an effective regimen for relapsed and refractory multiple myeloma patientsQ46830779
Bortezomib, melphalan, prednisone, and thalidomide for relapsed multiple myelomaQ79407795
Lenalidomide and pegylated liposomal doxorubicin-based chemotherapy for relapsed or refractory multiple myeloma: safety and efficacyQ80277048
Second autologous transplantation for multiple myeloma patients relapsing after the first autograft -- a pilot study for the evaluation of experimental maintenance therapies. Report of the prospective non-randomized pilot study of the Czech MyelomaQ80332966
Prolonged overall survival with second on-demand autologous transplant in multiple myelomaQ83300465
A phase 2 study of bortezomib in relapsed, refractory myelomaQ33348702
A phase 2 study of two doses of bortezomib in relapsed or refractory myelomaQ33363081
Bortezomib in combination with intermediate-dose dexamethasone and continuous low-dose oral cyclophosphamide for relapsed multiple myelomaQ33375805
Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progressionQ33376149
Lenalidomide plus dexamethasone for relapsed or refractory multiple myelomaQ33377526
Bortezomib, doxorubicin and dexamethasone in advanced multiple myeloma.Q33378895
Safety and efficacy of bortezomib and melphalan combination in patients with relapsed or refractory multiple myeloma: updated results of a phase 1/2 study after longer follow-upQ33379528
Phase I-II trial of bortezomib plus oral cyclophosphamide and prednisone in relapsed and refractory multiple myelomaQ33380452
High response rate to bortezomib with or without dexamethasone in patients with relapsed or refractory multiple myeloma: results of a global phase 3b expanded access programQ33382175
Lenalidomide, adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: a report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom).Q33383048
Bortezomib, low-dose intravenous melphalan, and dexamethasone for patients with relapsed multiple myelomaQ33383056
Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myelomaQ33386052
Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myelomaQ33386405
Clinical efficacy of a bortezomib, cyclophosphamide, thalidomide, and dexamethasone (Vel-CTD) regimen in patients with relapsed or refractory multiple myeloma: a phase II studyQ33387077
Bortezomib, doxorubicin, and dexamethasone combination therapy followed by thalidomide and dexamethasone consolidation as a salvage treatment for relapsed or refractory multiple myeloma: analysis of efficacy and safetyQ33388971
Lenalidomide, melphalan, prednisone and thalidomide (RMPT) for relapsed/refractory multiple myeloma.Q33389075
Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myelomaQ33401018
Lenalidomide plus dexamethasone for relapsed multiple myeloma in North AmericaQ34585268
A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myelomaQ35848744
Improved survival in multiple myeloma and the impact of novel therapiesQ36478461
Second auto-SCT is safe and effective salvage therapy for relapsed multiple myelomaQ37375819
Phase I study of vorinostat in combination with bortezomib for relapsed and refractory multiple myelomaQ37379984
The addition of cyclophosphamide to lenalidomide and dexamethasone in multiply relapsed/refractory myeloma patients; a phase I/II study.Q43018754
Vorinostat plus bortezomib for the treatment of relapsed/refractory multiple myeloma: a case series illustrating utility in clinical practiceQ43108148
Frail elderly patients with relapsed-refractory multiple myeloma: efficacy and toxicity profile of the combination of bortezomib, high-dose dexamethasone, and low-dose oral cyclophosphamideQ43115837
Weekly bortezomib, pegylated liposomal doxorubicin, and dexamethasone is a safe and effective therapy for elderly patients with relapsed/refractory multiple myelomaQ43132808
Retreatment with bortezomib alone or in combination for patients with multiple myeloma following an initial response to bortezomibQ43280884
P921main subjectchemotherapyQ974135
stem cell transplantationQ65592366
P304page(s)310-313
P577publication date2010-01-01
P1433published inHematology / the Education Program of the American Society of HematologyQ26842068
P1476titleEvidence-based mini-review: treatment options for patients with relapsed/refractory myeloma previously treated with novel agents and high-dose chemotherapy and autologous stem-cell transplantation
P478volume2010

Reverse relations

cites work (P2860)
Q35989943European perspective on multiple myeloma treatment strategies: update following recent congresses
Q33404749Good clinical activity and favorable toxicity profile of once weekly bortezomib, fotemustine, and dexamethasone (B-MuD) for the treatment of relapsed multiple myeloma
Q48402275Impact of the treatment-free interval on health-related quality of life in patients with multiple myeloma: a UK cross-sectional survey
Q47196540Matched-pair analysis to compare the outcomes of a second salvage auto-SCT to systemic chemotherapy alone in patients with multiple myeloma who relapsed after front-line auto-SCT.
Q35603152The immune microenvironment of myeloma
Q37949201Treatment strategies in relapsed and refractory multiple myeloma: a focus on drug sequencing and 'retreatment' approaches in the era of novel agents.

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