Jürgen Götz

researcher

Jürgen Götz is …
instance of (P31):
humanQ5

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P6178Dimensions author ID013113543217.79
P1960Google Scholar author ID67UrhCQAAAAJ
P496ORCID iD0000-0001-8501-7896
P3829Publons author ID2558023
P1053ResearcherIDC-2448-2014
P1153Scopus author ID7006610653
P10861Springer Nature person ID013113543217.79

P734family nameGötzQ21506953
GötzQ21506953
GötzQ21506953
P735given nameJürgenQ2670311
JürgenQ2670311
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

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author (P50)
Q36817223A decade of tau transgenic animal models and beyond
Q36758530A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions
Q53197946A neuroprotective role for the DNA damage checkpoint in tauopathy.
Q34100797Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction
Q40116267Abeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry
Q37678181Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse model
Q47844346Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice
Q35791948Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice
Q43475117Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice
Q48694512Active immunization trial in Abeta42-injected P301L tau transgenic mice
Q37313547Aging in the nervous system of Caenorhabditis elegans.
Q38409405Aging-Related Dysfunction of Striatal Cholinergic Interneurons Produces Conflict in Action Selection.
Q40219547Altered levels of PP2A regulatory B/PR55 isoforms indicate role in neuronal differentiation
Q48492272Altered phosphorylation but no neurodegeneration in a mouse model of tau hyperphosphorylation
Q48597411Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice
Q34038251Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome
Q112293556Altered ribosomal function and protein synthesis caused by tau
Q53246225Alzheimer's and Parkinson's disease--overlapping or synergistic pathologies?
Q36193841Alzheimer's disease models and functional genomics-How many needles are there in the haystack?
Q37543949Alzheimer's disease selective vulnerability and modeling in transgenic mice
Q26865759Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship
Q37414108Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
Q35909424Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models
Q37824813Amyloid-β and tau--a toxic pas de deux in Alzheimer's disease
Q42472271Analysis of the cholinergic pathology in the P301L tau transgenic pR5 model of tauopathy
Q28749702Animal models for Alzheimer's disease and frontotemporal dementia: a perspective
Q37196122Animal models of Alzheimer's disease and frontotemporal dementia
Q37596653Animal models reveal role for tau phosphorylation in human disease
Q36484083Antiviral CD8 T cells recognize borna disease virus antigen transgenically expressed in either neurons or astrocytes
Q58616121Are you me? Amyloid-β blocks the conversation between lysosomes and mitochondria
Q73774228Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
Q40207204Beta-amyloid treatment of two complementary P301L tau-expressing Alzheimer's disease models reveals similar deregulated cellular processes
Q48578686Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans
Q37650426Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease
Q37893588Brief update on different roles of tau in neurodegeneration
Q83225179Cell-specific non-canonical amino acid labelling identifies changes in the de novo proteome during memory formation
Q36778845Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease
Q33603862Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model
Q37407854Common features between diabetes mellitus and Alzheimer's disease
Q43660921Compartmentalized tau hyperphosphorylation and increased levels of kinases in transgenic mice
Q26996848Connecting the dots between tau dysfunction and neurodegeneration
Q33876147Convergence of amyloid-beta and tau pathologies on mitochondria in vivo
Q33987984Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons
Q38041425Decoding the non-coding RNAs in Alzheimer's disease
Q91578534Decreased synthesis of ribosomal proteins in tauopathy revealed by non-canonical amino acid labelling
Q28506401Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha
Q28119018Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
Q40361832Different tau epitopes define Abeta42-mediated tau insolubility
Q33307478Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils
Q90410907Disease-associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria
Q42649283Dissecting toxicity of tau and beta-amyloid
Q28507700Distinct role of protein phosphatase 2A subunit Calpha in the regulation of E-cadherin and beta-catenin during development
Q49031725Divergent phosphorylation pattern of tau in P301L tau transgenic mice
Q48429500Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A.
Q36513243Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?
Q35636403ENU mutagenesis screen to establish motor phenotypes in wild-type mice and modifiers of a pre-existing motor phenotype in tau mutant mice
Q42488398Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2.
Q58027784Erratum: Corrigendum: Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans
Q104798839Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol
Q49962856Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons
Q30913572Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease
Q48479400Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
Q39777445Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia
Q39447040Extracellular Vesicles Containing P301L Mutant Tau Accelerate Pathological Tau Phosphorylation and Oligomer Formation but Do Not Seed Mature Neurofibrillary Tangles in ALZ17 Mice
Q37066447Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner
Q28238356FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations
Q38457811FTD and ALS--translating mouse studies into clinical trials
Q43718666Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
Q64974468Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines.
Q33223501Functional Genomics meets neurodegenerative disorders Part I: transcriptomic and proteomic technology
Q31005421Functional Genomics meets neurodegenerative disorders. Part II: application and data integration
Q37103035Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response
Q39743618Gateway-compatible lentiviral transfer vectors for ubiquitin promoter driven expression of fluorescent fusion proteins
Q40516271Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice
Q34956464Glial cells under physiologic and pathologic conditions
Q42218060Glutamate Receptors in Alzheimer's Disease: Mechanisms and Therapies
Q36840001Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation
Q48630800Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis
Q38129226How it all started: tau and protein phosphatase 2A.
Q34779219Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures
Q33559266Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segment
Q40838026Immature human NT2 cells grafted into mouse brain differentiate into neuronal and glial cell types.
Q58028302Impact of β-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models
Q58028309Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice
Q48436885Impaired spatial reference memory and increased exploratory behavior in P301L tau transgenic mice
Q47575586Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia
Q34148195In vivo analysis of wild-type and FTDP-17 tau transgenic mice.
Q28478362Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol
Q37960973Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio
Q37080680Lessons from two prevalent amyloidoses-what amylin and Aβ have in common
Q58027510Local Oxidative Damage in the Soma and Dendrites Quarantines Neuronal Mitochondria at the Site of Insult
Q112284038Low-intensity ultrasound restores long-term potentiation and memory in senescent mice through pleiotropic mechanisms including NMDAR signaling
Q38139701March separate, strike together--role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease
Q30473576Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta
Q37961383MicroRNA networks surrounding APP and amyloid-β metabolism--implications for Alzheimer's disease
Q90179343Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies
Q35579318Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity
Q37064222Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant Tau
Q57131006Modeling ultrasound propagation through material of increasing geometrical complexity
Q35235869Modes of Aβ toxicity in Alzheimer's disease
Q40416715Molecular dissection of the paired helical filament
Q40656151Motor cortical function determines prognosis in sporadic ALS.
Q39088915Mouse models of frontotemporal dementia: A comparison of phenotypes with clinical symptomatology
Q37252419Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation
Q33605734Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta
Q43145279Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress
Q33821316Neuroproteomics as a promising tool in Parkinson's disease research
Q43120289No full admission for tau to the exclusive prion club yet.
Q58028373Non-tolerance and differential susceptibility to diabetes in transgenic mice expressing major histocompatibility class II genes on pancreatic β cells
Q43650971Oligodendroglial tau filament formation in transgenic mice expressing G272V tau.
Q48963010Oligomeric and fibrillar species of beta-amyloid (A beta 42) both impair mitochondrial function in P301L tau transgenic mice
Q58028320P2-110 Amyloid-induced neurofibrillary tangle formation addressed in vivo and in vitro
Q40338655P70 S6 kinase mediates tau phosphorylation and synthesis
Q90821793PTEN activation contributes to neuronal and synaptic engulfment by microglia in tauopathy
Q33798637PTL-1 regulates neuronal integrity and lifespan in C. elegans
Q37790149Parkinson's disease: insights from non-traditional model organisms
Q36948965Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
Q58028289Pathogenetic mechanisms in Down Syndrome
Q48244476Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic mice
Q37344062Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease
Q48480842Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains
Q48182654Possibilities for the prevention and treatment of cognitive impairment and dementia
Q35843373Posttranslational modifications of tau--role in human tauopathies and modeling in transgenic animals
Q30578448Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn.
Q58028272Primary support cultures of hippocampal and substantia nigra neurons
Q35081058Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus
Q34633979Pronuclear injection for the production of transgenic mice
Q47814284Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice
Q48391254Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines
Q37016360Quantitative Imaging of Cholinergic Interneurons Reveals a Distinctive Spatial Organization and a Functional Gradient across the Mouse Striatum.
Q43687951Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice.
Q58028116Reduced secretagogin expression in the hippocampus of P301L tau transgenic mice
Q40497520Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reaction
Q33713496Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous.
Q58028273Response to the comment ‘Iron, type 2 diabetes mellitus, and Alzheimer’s disease’ to our Visions and Reflections article ‘Common features between diabetes mellitus and Alzheimer’s disease’
Q58027500Rodent models for Alzheimer disease
Q34336935Role for glyoxalase I in Alzheimer's disease.
Q43983408Role of hippocalcin in mediating Aβ toxicity
Q58028318Role of the protein tau in Alzheimer's disease
Q58028329S.03.01 In vivo and in vitro models of AD demonstrate a role of distinct phosphorylation sites of tau in neurofibrillary tangle formation
Q58028312S.23.02 Transgenic animal models of Alzheimer's disease
Q35472266Saitohin gene is not associated with Alzheimer's disease
Q36160523Scanning Ultrasound (SUS) Causes No Changes to Neuronal Excitability and Prevents Age-Related Reductions in Hippocampal CA1 Dendritic Structure in Wild-Type Mice
Q34043432Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model
Q36426980Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein
Q47994216Shedding light on mitophagy in neurons: what is the evidence for PINK1/Parkin mitophagy in vivo?
Q45912754Single nucleotide variants (SNVs) define senescence-accelerated SAMP8 mice, a model of a geriatric condition.
Q34068459Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models
Q58028291Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice
Q47867970Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation
Q48461987Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'.
Q53397821Substrate-specific reduction of PP2A activity exaggerates tau pathology.
Q49104984Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.
Q35008256Tau aggregation and its interplay with amyloid-β.
Q58028348Tau and transgenic animal models
Q31442641Tau filament formation in transgenic mice expressing P301L tau.
Q28070250Tau physiology and pathomechanisms in frontotemporal lobar degeneration
Q28119104Tau promotes neurodegeneration via DRP1 mislocalization in vivo
Q34256620Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease
Q34102829Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice
Q27023429Tau-targeted treatment strategies in Alzheimer's disease
Q48650483Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice
Q58028359The Role of Protein Phosphatase 2A Catalytic Subunit Cα in Embryogenesis: Evidence from Sequence Analysis and Localization Studies
Q46368794The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation.
Q38778723The frontotemporal dementia-motor neuron disease continuum
Q39012769The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells
Q90091361The search for improved animal models of Alzheimer's disease and novel strategies for therapeutic intervention
Q48117016Transgenic and knockout models of PP2A.
Q35723358Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.
Q37009753Transgenic mice expressing the nucleoprotein of Borna disease virus in either neurons or astrocytes: decreased susceptibility to homotypic infection and disease
Q58028292Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma
Q38739505Ultrasound treatment of neurological diseases--current and emerging applications
Q93024737Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody
Q39014131Visualizing the microtubule-associated protein tau in the nucleus
Q36914658What Renders TAU Toxic
Q35215656What we can learn from animal models about cerebral multi-morbidity
Q38098662Why size matters - balancing mitochondrial dynamics in Alzheimer's disease
Q44534307beta-Amyloid induces paired helical filament-like tau filaments in tissue culture

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