scholarly article | Q13442814 |
P356 | DOI | 10.4155/FMC.09.155 |
P698 | PubMed publication ID | 21426194 |
P50 | author | Theocharis Panaretakis | Q40049207 |
P2093 | author name string | Dan Grandér | |
P2860 | cites work | Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis | Q24294860 |
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1 | Q24303558 | ||
DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy | Q24323360 | ||
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | Q24597817 | ||
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress | Q24633606 | ||
Autophagy suppresses tumorigenesis through elimination of p62 | Q24650670 | ||
Regulation of autophagy by cytoplasmic p53 | Q24651258 | ||
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 | Q24670840 | ||
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling | Q24672005 | ||
The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway | Q24678032 | ||
Autophagy in the Pathogenesis of Disease | Q27860558 | ||
TSC2 mediates cellular energy response to control cell growth and survival | Q27860970 | ||
A ubiquitin-like system mediates protein lipidation | Q27934137 | ||
Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion | Q27934199 | ||
Induction of autophagy and inhibition of tumorigenesis by beclin 1 | Q28131718 | ||
The AMP-activated protein kinase cascade--a unifying system for energy control | Q28239257 | ||
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease | Q28261987 | ||
Metabolic profiles of cancer cells | Q28269762 | ||
Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines | Q28474545 | ||
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin | Q28590162 | ||
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy | Q29614479 | ||
FoxO3 controls autophagy in skeletal muscle in vivo | Q29614483 | ||
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum | Q29614500 | ||
Autophagy defends cells against invading group A Streptococcus | Q29615620 | ||
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG | Q29615716 | ||
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis | Q29616308 | ||
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism | Q29617261 | ||
Role of autophagy in cancer | Q29620348 | ||
The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis | Q29622875 | ||
Apoptosis inhibition by Bcl-2 gives way to autophagy in glucocorticoid-treated lymphocytes | Q30538797 | ||
Arsenic trioxide induces not only apoptosis but also autophagic cell death in leukemia cell lines via up-regulation of Beclin-1. | Q33252513 | ||
Dynamic effects of autophagy on arsenic trioxide-induced death of human leukemia cell line HL60 cells | Q33312343 | ||
Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma | Q33366976 | ||
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases | Q33613123 | ||
Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3. | Q34375642 | ||
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation | Q40066410 | ||
Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells | Q40071790 | ||
The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion | Q40085993 | ||
Arsenic salts induced autophagic cell death and hypermethylation of DAPK promoter in SV-40 immortalized human uroepithelial cells | Q40096979 | ||
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. | Q40202994 | ||
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death. | Q40419639 | ||
Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells | Q40600919 | ||
The ARF tumor suppressor can promote the progression of some tumors. | Q41819519 | ||
Autophagy in aging, disease and death: the true identity of a cell death impostor | Q42609173 | ||
Early detection of graft failure using the blood metabolic profile of a liver recipient | Q43095449 | ||
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy | Q43991443 | ||
Life and death partners: apoptosis, autophagy and the cross-talk between them | Q46072576 | ||
A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells | Q46109715 | ||
Regulation of estrogenic effects by beclin 1 in breast cancer cells | Q46336425 | ||
Oxidation as a post-translational modification that regulates autophagy | Q48405295 | ||
Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor | Q51455030 | ||
Apoptosis and autophagy in photoreceptors exposed to oxidative stress | Q53556342 | ||
Autophagy and cancer | Q56772657 | ||
Chronic Lymphocytic Leukemia: Keeping Cell Death at Bay | Q57253596 | ||
ROS, mitochondria and the regulation of autophagy | Q34679713 | ||
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy | Q34763495 | ||
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4. | Q34872907 | ||
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability | Q34938849 | ||
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy | Q34948698 | ||
Autophagy: in sickness and in health | Q35753167 | ||
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance | Q35850687 | ||
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis | Q35855667 | ||
Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability | Q35916071 | ||
Protein degradation and aging | Q36241977 | ||
Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components | Q37015051 | ||
Tuberous sclerosis complex, implication from a rare genetic disease to common cancer treatment | Q37134137 | ||
ARF, autophagy and tumor suppression. | Q37155201 | ||
Therapeutic activity of mTOR inhibitors in mantle cell lymphoma: clues but no clear answers | Q37158978 | ||
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells | Q37170788 | ||
Clinical applications of metabolomics in oncology: a review | Q37177549 | ||
Autophagy genes in immunity | Q37273997 | ||
The paradox of autophagy and its implication in cancer etiology and therapy | Q37378496 | ||
AMPK/SNF1 structure: a menage a trois of energy-sensing | Q37410000 | ||
Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression | Q37469223 | ||
The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib | Q39856430 | ||
Superoxide is the major reactive oxygen species regulating autophagy | Q39858156 | ||
Stimulation of autophagy by the p53 target gene Sestrin2. | Q39859248 | ||
RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia | Q39861488 | ||
PUMA- and Bax-induced autophagy contributes to apoptosis | Q39870608 | ||
Autophagy facilitates the progression of ERalpha-positive breast cancer cells to antiestrogen resistance | Q39883237 | ||
Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells | Q39910064 | ||
SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway | Q39930036 | ||
Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells. | Q39959646 | ||
Vitamin D3 induces autophagy of human myeloid leukemia cells | Q39961212 | ||
The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias | Q39962747 | ||
Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells | Q39996922 | ||
Vitamin K2 induces autophagy and apoptosis simultaneously in leukemia cells | Q39997033 | ||
Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma | Q40002119 | ||
Blocked autophagy sensitizes resistant carcinoma cells to radiation therapy | Q40006232 | ||
P433 | issue | 2 | |
P921 | main subject | autophagy | Q288322 |
P304 | page(s) | 285-297 | |
P577 | publication date | 2010-02-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Future Medicinal Chemistry | Q19280078 |
P1476 | title | Autophagy: cancer therapy's friend or foe? | |
P478 | volume | 2 |
Q57809709 | AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields) |
Q35319792 | Autophagy during beef aging |
Q55213455 | Autophagy inhibition enhances radiosensitivity of Eca‑109 cells via the mitochondrial apoptosis pathway. |
Q34389503 | Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses |
Q37468676 | High dose of extracellular ATP switched autophagy to apoptosis in anchorage-dependent and anchorage-independent hepatoma cells |
Q93111157 | MTMR3 is upregulated in patients with breast cancer and regulates proliferation, cell cycle progression and autophagy in breast cancer cells |
Q57050339 | Microgravity induces autophagy via mitochondrial dysfunction in human Hodgkin's lymphoma cells |
Q35558057 | Novel and emerging targeted-based cancer therapy agents and methods |
Q89909298 | Resveratrol suppresses melanoma growth by promoting autophagy through inhibiting the PI3K/AKT/mTOR signaling pathway |
Q38261907 | Sorafenib-induced defective autophagy promotes cell death by necroptosis |
Q38579547 | Targeting autophagy to overcome drug resistance in cancer therapy |
Q35723957 | Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells |
Q47138725 | The downregulation of ATG4B mediated by microRNA-34a/34c-5p suppresses rapamycin-induced autophagy |
Q39726023 | The expression of p33ING1, p53, and autophagy-related gene Beclin1 in patients with non-small cell lung cancer |
Q28483781 | The inhibition of autophagy sensitises colon cancer cells with wild-type p53 but not mutant p53 to topotecan treatment |
Q37151496 | The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation. |
Q39715088 | The significance of expression of autophagy-related gene Beclin, Bcl-2, and Bax in breast cancer tissues |
Q61445010 | WZY-321, a novel evodiamine analog, inhibits glioma cell growth in an autophagy-associated manner |
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