review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Robert W Gereau | |
Michael C Montana | |||
P2860 | cites work | (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord | Q24290799 |
The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine | Q24648725 | ||
A pilot open label, single dose trial of fenobam in adults with fragile X syndrome. | Q24654933 | ||
Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism | Q24674309 | ||
Selective agonist of group II glutamate metabotropic receptors, LY354740, inhibits tolerance to analgesic effects of morphine in mice | Q24674933 | ||
The neuroactive peptide N-acetylaspartylglutamate is not an agonist at the metabotropic glutamate receptor subtype 3 of metabotropic glutamate receptor | Q28242378 | ||
The anxiolytic and analgesic properties of fenobam, a potent mGlu5 receptor antagonist, in relation to the impairment of learning | Q28244264 | ||
Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain - relation to brain concentration | Q28259391 | ||
Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity | Q28263355 | ||
Treatment of anxiety using fenobam (a nonbenzodiazepine) in a double-blind standard (diazepam) placebo-controlled study | Q28277501 | ||
Sequence and expression of a metabotropic glutamate receptor | Q28280066 | ||
Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats | Q28284443 | ||
2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist | Q28374719 | ||
Metabotropic glutamate receptor subtypes 1 and 5 are activators of extracellular signal-regulated kinase signaling required for inflammatory pain in mice | Q28571306 | ||
Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors | Q28583394 | ||
Metabotropic glutamate receptor 5 modulates nociceptive plasticity via extracellular signal-regulated kinase-Kv4.2 signaling in spinal cord dorsal horn neurons | Q28589995 | ||
Pharmacology and functions of metabotropic glutamate receptors | Q29619150 | ||
Acetyl-L-carnitine in neuropathic pain: experimental data. | Q31121719 | ||
mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors | Q31725764 | ||
Immunohistochemical localization of metabotropic glutamate receptors mGluR1a and mGluR2/3 in the rat basal ganglia | Q32129579 | ||
Pharmacological agents acting at subtypes of metabotropic glutamate receptors | Q33756933 | ||
Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats | Q33918671 | ||
Activation of metabotropic glutamate receptor 5 in the amygdala modulates pain-like behavior. | Q33969445 | ||
Reactive oxygen species are involved in group I mGluR-mediated facilitation of nociceptive processing in amygdala neurons | Q33995347 | ||
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity | Q34169306 | ||
A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo | Q34234693 | ||
mGluR7's lucky number | Q34249852 | ||
Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. | Q34326346 | ||
Assessing the role of metabotropic glutamate receptor 5 in multiple nociceptive modalities | Q34374805 | ||
The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles | Q34389636 | ||
The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison | Q34399005 | ||
Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. | Q34564332 | ||
Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice | Q34582656 | ||
ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activiti | Q34815750 | ||
Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine | Q34997110 | ||
Metabotropic glutamate receptor involvement in models of acute and persistent pain: prospects for the development of novel analgesics | Q35137409 | ||
Physiological roles and therapeutic potential of metabotropic glutamate receptors | Q35610972 | ||
Unmasking the tonic-aversive state in neuropathic pain | Q36189364 | ||
Metabotropic glutamate receptors. | Q36539070 | ||
A proof-of-concept study evaluating the effect of ADX10059, a metabotropic glutamate receptor-5 negative allosteric modulator, on acid exposure and symptoms in gastro-oesophageal reflux disease | Q37284534 | ||
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders | Q37360436 | ||
Animal models of pain: progress and challenges | Q37405925 | ||
Hemispheric lateralization of pain processing by amygdala neurons | Q37420261 | ||
Glutamatergic fine tuning with ADX-10059: a novel therapeutic approach for migraine? | Q37706619 | ||
Acetyl-l-carnitine induces muscarinic antinocieption in mice and rats | Q39399681 | ||
Metabotropic glutamate receptor subtype 5 (mGlu5) and nociceptive function. I. Selective blockade of mGlu5 receptors in models of acute, persistent and chronic pain. | Q39551983 | ||
mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia. | Q39551989 | ||
Role of metabotropic glutamate receptor subtype 5 (mGluR5) in the maintenance of cold hypersensitivity following a peripheral mononeuropathy in the rat. | Q39650134 | ||
Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model | Q40539364 | ||
Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain | Q42397202 | ||
Attenuation of morphine tolerance after antisense oligonucleotide knock-down of spinal mGluR1. | Q43263727 | ||
The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat. | Q43294948 | ||
Glutamate receptor ligands attenuate allodynia and hyperalgesia and potentiate morphine effects in a mouse model of neuropathic pain | Q43479332 | ||
Spinal N-acetyl-alpha-linked acidic dipeptidase (NAALADase) inhibition attenuates mechanical allodynia induced by paw carrageenan injection in the rat. | Q43691638 | ||
Metabotropic glutamate 1alpha receptors on peripheral primary afferent fibers: their role in nociception | Q43725859 | ||
L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors | Q43964695 | ||
Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. | Q44085153 | ||
Inhibitory effects of MPEP, an mGluR5 antagonist, and memantine, an N-methyl-D-aspartate receptor antagonist, on morphine antinociceptive tolerance in mice | Q44222958 | ||
mGluR2 postsynaptically senses granule cell inputs at Golgi cell synapses | Q44568735 | ||
Differential roles of mGluR1 and mGluR5 in brief and prolonged nociceptive processing in central amygdala neurons | Q44588615 | ||
Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials | Q45199374 | ||
mGluR1 and mGluR5 antagonists in the amygdala inhibit different components of audible and ultrasonic vocalizations in a model of arthritic pain | Q45203674 | ||
Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain | Q46102945 | ||
Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing | Q46584768 | ||
Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats | Q46869697 | ||
Excitatory amino acid antagonists (kynurenic acid and MK-801) attenuate the development of morphine tolerance in the rat | Q46904809 | ||
Involvement of metabotropic glutamate 5 receptor in visceral pain. | Q46949614 | ||
Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception | Q48165590 | ||
Role of metabotropic glutamate receptor subtype mGluR1 in brief nociception and central sensitization of primate STT cells | Q48166951 | ||
Activation of the extracellular signal-regulated kinase in the amygdala modulates pain perception. | Q48272564 | ||
Cellular localization of a metabotropic glutamate receptor in rat brain | Q48453181 | ||
Metabotropic glutamate group II receptors activate a G protein-coupled inwardly rectifying K+ current in neurones of the rat cerebellum | Q48476731 | ||
Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain | Q48506273 | ||
Subjective ratings of pain correlate with subcortical-limbic blood flow: an fMRI study | Q48926361 | ||
Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells | Q49162350 | ||
mGluR5 metabotropic glutamate receptor distribution in rat and human spinal cord: a developmental study. | Q52194745 | ||
Differential distribution of metabotropic glutamate receptor subtype mRNAs in the thalamus of the rat | Q60688651 | ||
The involvement of metabotropic glutamate receptors and their intracellular signalling pathways in sustained nociceptive transmission in rat dorsal horn neurons | Q70812965 | ||
Requirement of Metabotropic Glutamate Receptors for the Generation of Inflammation‐evoked Hyperexcitability in Rat Spinal Cord Neurons | Q71655178 | ||
Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3 | Q71870839 | ||
Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons | Q72420535 | ||
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception | Q73275106 | ||
N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells | Q73456893 | ||
Periaqueductal gray matter metabotropic glutamate receptors modulate formalin-induced nociception | Q73487783 | ||
Behavioural evidence supporting a differential role for group I and II metabotropic glutamate receptors in spinal nociceptive transmission | Q73665641 | ||
Antisense oligonucleotide knockdown of mGluR1 alleviates hyperalgesia and allodynia associated with chronic inflammation | Q74461043 | ||
Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats | Q74461047 | ||
Metabotropic glutamate receptors in superficial laminae of the rat dorsal horn | Q77976063 | ||
Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation | Q79349616 | ||
Colocalization of metabotropic glutamate receptors in rat dorsal root ganglion cells | Q79772767 | ||
Peripheral group I metabotropic glutamate receptors modulate nociception in mice | Q95721089 | ||
P433 | issue | 10 | |
P304 | page(s) | 1681-1688 | |
P577 | publication date | 2011-10-01 | |
P1433 | published in | Current Pharmaceutical Biotechnology | Q15763083 |
P1476 | title | Metabotropic glutamate receptors as targets for analgesia: antagonism, activation, and allosteric modulation | |
P478 | volume | 12 |
Search more.