| scholarly article | Q13442814 |
| P2093 | author name string | A I Faden | |
| V Movsesyan | |||
| D M O'Leary | |||
| S Vicini | |||
| P2860 | cites work | Latest eruptions in metabotropic glutamate receptors | Q73027034 |
| (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus | Q73326355 | ||
| Metabotropic glutamate receptors: electrophysiological properties and role in plasticity | Q78111516 | ||
| Neuroprotective effects of group III mGluR in traumatic neuronal injury | Q28262691 | ||
| Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells | Q28271408 | ||
| 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist | Q28374719 | ||
| SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5 | Q28378193 | ||
| The metabotropic glutamate receptors: structure and functions | Q28611140 | ||
| Pharmacology and functions of metabotropic glutamate receptors | Q29619150 | ||
| Pharmacological agents acting at subtypes of metabotropic glutamate receptors | Q33756933 | ||
| N-methyl-D-aspartate antagonist MK801 improves outcome following traumatic spinal cord injury in rats: behavioral, anatomic, and neurochemical studies | Q34164446 | ||
| New in vitro model of traumatic neuronal injury: evaluation of secondary injury and glutamate receptor-mediated neurotoxicity | Q34443091 | ||
| Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1. | Q36703769 | ||
| Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury | Q37602939 | ||
| Metabotropic glutamate receptors: novel targets for drug development | Q40518456 | ||
| Factors affecting excitatory amino acid release following severe human head injury | Q40840971 | ||
| Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? | Q41107509 | ||
| Comparing the role of metabotropic glutamate receptors in long-term potentiation and in learning and memory | Q41164944 | ||
| Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands | Q41922155 | ||
| Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. | Q42551346 | ||
| Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes | Q42557875 | ||
| Metabotropic glutamate antagonist, MCPG, treatment of traumatic brain injury in rats | Q45096525 | ||
| The effect of NMDA, AMPA/kainate, and calcium channel antagonists on traumatic cortical neuronal injury in culture | Q48191246 | ||
| Metabotropic glutamate receptor activation and blockade: their role in long-term potentiation, learning and neurotoxicity | Q48283480 | ||
| Antagonists for group I mGluRs attenuate excitotoxic neuronal death in cortical cultures | Q48383223 | ||
| Mechanical injury to neuronal/glial cultures in microplates: role of NMDA receptors and pH in secondary neuronal cell death | Q48490138 | ||
| Pretreatment with NMDA antagonists limits release of excitatory amino acids following traumatic brain injury | Q48510758 | ||
| mGluR modulation of post-traumatic neuronal death: role of NMDA receptors | Q48655340 | ||
| Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury | Q48912120 | ||
| Activation of group III metabotropic glutamate receptors is neuroprotective in cortical cultures | Q48940426 | ||
| Role of Group I Metabotropic Glutamate Receptors in Traumatic Spinal Cord White Matter Injury | Q57839889 | ||
| Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons | Q60686743 | ||
| Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 r | Q63484490 | ||
| The role of excitatory amino acids and NMDA receptors in traumatic brain injury | Q69370501 | ||
| Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses | Q70813007 | ||
| 3,5-dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus | Q72069910 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | toxicity | Q274160 |
| P304 | page(s) | 1429-37 | |
| P577 | publication date | 2000-12-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism | |
| P478 | volume | 131 |
| Q43264834 | 2-Methyl-6-phenylethynyl-pyridine (MPEP), a non-competitive mGluR5 antagonist, differentially affects the anticonvulsant activity of four conventional antiepileptic drugs against amygdala-kindled seizures in rats |
| Q37617118 | A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats |
| Q44261091 | Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors |
| Q44345706 | Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission |
| Q33907912 | Activation of mGluR5 attenuates NMDA-induced neurotoxicity through disruption of the NMDAR-PSD-95 complex and preservation of mitochondrial function in differentiated PC12 cells |
| Q33754643 | Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy--implications for excitotoxicity |
| Q36449439 | An interchangeable role for kainate and metabotropic glutamate receptors in the induction of rat hippocampal mossy fiber long-term potentiation in vivo. |
| Q36877121 | Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: comparison with dizocilpine |
| Q42165854 | Behavioral sensitization due to social defeat stress in mice: antagonism at mGluR5 and NMDA receptors |
| Q48642843 | Blockade of metabotropic glutamate receptor 5 activation inhibits mechanical hypersensitivity following abdominal surgery |
| Q43728731 | Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rats |
| Q28577999 | Co-stimulation of mGluR5 and N-Methyl-D-aspartate Receptors Is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons |
| Q48493181 | Complex interactions between mGluR1 and mGluR5 shape neuronal network activity in the rat hippocampus |
| Q35657336 | Differential Modulation of Thresholds for Intracranial Self-Stimulation by mGlu5 Positive and Negative Allosteric Modulators: Implications for Effects on Drug Self-Administration. |
| Q36871587 | Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice |
| Q34714448 | Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine |
| Q35960336 | Double Dissociation of the Roles of Metabotropic Glutamate Receptor 5 and Oxytocin Receptor in Discrete Social Behaviors |
| Q42617355 | Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice |
| Q46658078 | Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats. |
| Q34555481 | Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats |
| Q37415168 | Effects of subtype-selective group I mGluR antagonists on synchronous activity induced by 4-aminopyridine/CGP 55845 in adult guinea pig hippocampal slices |
| Q42980923 | Effects of the mGluR5 antagonist MPEP on ethanol withdrawal induced anxiety-like syndrome in rats. |
| Q44746550 | Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. |
| Q90002915 | Excitotoxic neurodegeneration is associated with a focal decrease in metabotropic glutamate receptor type 5 availability: an in vivo PET imaging study |
| Q82029465 | Excitotoxicity |
| Q34314041 | Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: implications for addiction treatment in humans. |
| Q34632916 | Fragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloid |
| Q30741143 | Functional genomics in experimental and human temporal lobe epilepsy: powerful new tools to identify molecular disease mechanisms of hippocampal damage |
| Q45279113 | Functional interaction between mGlu 5 and NMDA receptors in a rat model of Parkinson's disease |
| Q46684857 | GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons |
| Q38821888 | Glutamate levels control HT22 murine hippocampal cell death by regulating biphasic patterns of Erk1/2 activation: role of metabolic glutamate receptor 5. |
| Q28206435 | Glutamate metabotropic receptors as targets for drug therapy in epilepsy |
| Q44686787 | In the amygdala anxiolytic action of mGlu5 receptors antagonist MPEP involves neuropeptide Y but not GABAA signaling |
| Q38939473 | Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive Gi-proteins in murine BV-2 microglia cells |
| Q37206018 | Inhibition of the group I mGluRs reduces acute brain damage and improves long-term histological outcomes after photothrombosis-induced ischaemia |
| Q42968731 | Interaction of blockers of ionotropic NMDA receptors and metabotropic glutamate receptors in a working memory test in rats. |
| Q33752076 | Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens |
| Q93169508 | Involvement of mGluR5 and TRPV1 in visceral nociception in a rat model of uterine cervical distension |
| Q42525621 | Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity? |
| Q33749098 | Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking |
| Q36952480 | Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions |
| Q33787564 | Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake |
| Q35291239 | Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats |
| Q38239515 | Metabotropic glutamate receptor 5 as a potential therapeutic target in Huntington's disease |
| Q37280041 | Metabotropic glutamate receptor ligands as potential therapeutics for addiction |
| Q37723772 | Metabotropic glutamate receptor subtype 5 antagonism in learning and memory |
| Q34564332 | Metabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP. |
| Q28385047 | Metabotropic glutamate receptor-mediated signaling in neuroglia |
| Q46428813 | Metabotropic glutamate receptors 5 blockade reverses spatial memory deficits in a mouse model of Parkinson's disease |
| Q37861794 | Metabotropic glutamate receptors as targets for analgesia: antagonism, activation, and allosteric modulation |
| Q37358665 | Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders |
| Q34147832 | Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats |
| Q40437194 | NF-kappaB factor c-Rel mediates neuroprotection elicited by mGlu5 receptor agonists against amyloid beta-peptide toxicity. |
| Q26775243 | Negative Allosteric Modulators of Metabotropic Glutamate Receptors Subtype 5 in Addiction: a Therapeutic Window |
| Q48022620 | Negative versus positive allosteric modulation of metabotropic glutamate receptors (mGluR5): indices for potential pro-cognitive drug properties based on EEG network oscillations and sleep-wake organization in rats |
| Q34410375 | Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors |
| Q42754399 | Neuroprotective potential of mGluR5 antagonist MTEP: effects on kainate-induced excitotoxicity in the rat hippocampus |
| Q45297155 | New allosteric modulators of metabotropic glutamate receptor 5 (mGluR5) found by ligand-based virtual screening |
| Q34296075 | Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders |
| Q54985266 | Physiological activation of mGlu5 receptors supports the ion channel function of NMDA receptors in hippocampal LTD induction in vivo. |
| Q24672796 | Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP |
| Q43552423 | Protective effects of mGluR5 positive modulators against traumatic neuronal injury through PKC-dependent activation of MEK/ERK pathway |
| Q33685348 | Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP. |
| Q37790804 | Review: disruption of the postsynaptic density in Alzheimer's disease and other neurodegenerative dementias |
| Q39062204 | Role of transient receptor potential channel 1 (TRPC1) in glutamate-induced cell death in the hippocampal cell line HT22. |
| Q43823127 | Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia |
| Q42358716 | Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective |
| Q42505710 | Stimulation of group I mGlu receptors in the ventrotegmental area enhances extracellular dopamine in the rat medial prefrontal cortex |
| Q35216446 | The distinct role of mGlu1 receptors in post-ischemic neuronal death |
| Q34412442 | The effect of the mGlu5 negative allosteric modulator MTEP and NMDA receptor partial agonist D-cycloserine on Pavlovian conditioned fear. |
| Q34399005 | The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison |
| Q35740788 | The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats' performance in the 5-choice serial reaction time task |
| Q44037107 | The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala. |
| Q44801606 | The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats |
| Q49011181 | The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors |
| Q33788860 | The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice. |
| Q38924641 | The mGluR5 positive allosteric modulator CDPPB inhibits SO₂-induced protein radical formation and mitochondrial dysfunction through activation of Akt in mouse hippocampal HT22 cells |
| Q43568126 | The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures |
| Q44666716 | The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors |
| Q43996569 | The novel and systemically active metabotropic glutamate 1 (mGlu1) receptor antagonist 3-MATIDA reduces post-ischemic neuronal death |
| Q36003895 | The role of group I metabotropic glutamate receptors in neuronal excitotoxicity in Alzheimer's disease |
| Q35698522 | Therapeutic potential of mGluR5 targeting in Alzheimer's disease |
| Q36424785 | Translational Concepts of mGluR5 in Synaptic Diseases of the Brain |
| Q44736089 | mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior |
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