Glutamate levels control HT22 murine hippocampal cell death by regulating biphasic patterns of Erk1/2 activation: role of metabolic glutamate receptor 5.

scientific article published on 5 November 2015

Glutamate levels control HT22 murine hippocampal cell death by regulating biphasic patterns of Erk1/2 activation: role of metabolic glutamate receptor 5. is …
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scholarly articleQ13442814

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P356DOI10.1080/09168451.2015.1107466
P698PubMed publication ID26539627

P2093author name stringTaku Nedachi
Kazunori Sato
Yuki Yamanaka
Yasuharu Asakura
P2860cites workPotentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of extracellular signal-regulated kinase1/2 (ERK1/2) in conjunction with p38 kinase or c-jun N-terminal kinase (JNK). Complete inhibition of the potentiQ43799869
mGluR1/5 subtype-specific calcium signalling and induction of long-term potentiation in rat hippocampal oriens/alveus interneuronesQ48513863
Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonismQ24674309
Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activationQ28131755
Identification of a novel inhibitor of mitogen-activated protein kinase kinaseQ29616448
Cloned glutamate receptorsQ29619950
Constitutive reactive oxygen species generation from autophagosome/lysosome in neuronal oxidative toxicityQ33581452
Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptorsQ34410375
Therapeutic potential of mGluR5 targeting in Alzheimer's diseaseQ35698522
Metabotropic glutamate receptors in glial cells.Q37148385
Metabotropic glutamate receptor-dependent long-term potentiationQ37586419
mGluR1 within the nucleus accumbens regulates alcohol intake in mice under limited-access conditionsQ37642997
Molecular and cellular mechanisms of excitotoxic neuronal deathQ37704998
Excitotoxicity and stroke: identifying novel targets for neuroprotection.Q38173189
Researching glutamate - induced cytotoxicity in different cell lines: a comparative/collective analysis/studyQ38410871
Dual cell protective mechanisms activated by differing levels of oxidative stress in HT22 murine hippocampal cells.Q38971962
Extracellular hydrogen peroxide contributes to oxidative glutamate toxicityQ39659763
Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5--implications for dementia with Lewy bodiesQ40150743
Opposing roles for ERK1/2 in neuronal oxidative toxicity: distinct mechanisms of ERK1/2 action at early versus late phases of oxidative stressQ40290776
Activation of ERK1/2, JNK and PKB by hydrogen peroxide in human SH-SY5Y neuroblastoma cells: role of ERK1/2 in H2O2-induced cell deathQ40598528
Glutamate-induced cytotoxicity in PC12 pheochromocytoma cells: role of oxidation of phospholipids, glutathione and protein sulfhydryls revealed by bcl-2 transfectionQ41005377
Control of calcium oscillations by phosphorylation of metabotropic glutamate receptorsQ41168894
Protective effects of mGluR5 positive modulators against traumatic neuronal injury through PKC-dependent activation of MEK/ERK pathwayQ43552423
P433issue4
P921main subjectcell deathQ2383867
P1104number of pages7
P304page(s)712-718
P577publication date2015-11-05
P1433published inBioscience, Biotechnology, and BiochemistryQ11192374
P1476titleGlutamate levels control HT22 murine hippocampal cell death by regulating biphasic patterns of Erk1/2 activation: role of metabolic glutamate receptor 5.
P478volume80