Pharmacokinetic evaluation of zoledronic acid.

scientific article published on 13 May 2011

Pharmacokinetic evaluation of zoledronic acid. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1517/17425255.2011.585156
P698PubMed publication ID21563999

P50authorGennaro DanieleQ37828894
Nicola NormannoQ37828910
Antonella De LucaQ39048942
Marianna GalloQ81350050
Monica Rosaria MaielloQ104516503
Amelia D'AlessioQ116998254
Luana LamuraQ116998255
Pasqualina GiordanoQ116998256
Maria PergamenoQ116998257
P2093author name stringFrancesco Perrone
P2860cites workEnhanced tumor regression and tissue repair when zoledronic acid is combined with ifosfamide in rat osteosarcomaQ33215107
A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinomaQ34152748
Chemical and biological prerequisites for novel bisphosphonate molecules: results of comparative preclinical studiesQ34247899
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.Q34943802
Antitumor effects of bisphosphonatesQ35053955
Farnesyl diphosphate synthase is involved in the resistance to zoledronic acid of osteosarcoma cellsQ35458425
Recommendations for zoledronic acid treatment of patients with bone metastasesQ35999713
Human Vgamma9Vdelta2 T cells: promising new leads for immunotherapy of infections and tumorsQ36548005
Molecular mechanisms of action of bisphosphonates: current status.Q36633778
Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonatesQ37179393
Potential anticancer properties of bisphosphonates.Q37777494
Epidemiology and risk factors for osteonecrosis of the jaw in cancer patientsQ37800176
Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitroQ39860282
Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosisQ40311684
Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer modelQ40538169
A dose-finding study of zoledronate in hypercalcemic cancer patientsQ40799250
Bisphosphonates: a review of their pharmacokinetic propertiesQ41132404
Zoledronic acid inhibits both the osteolytic and osteoblastic components of osteosarcoma lesions in a mouse modelQ41497465
Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.Q42183397
Preclinical pharmacology of CGP 42'446, a new, potent, heterocyclic bisphosphonate compoundQ42283820
Repeated intermittent low-dose therapy with zoledronic acid induces an early, sustained, and long-lasting decrease of peripheral vascular endothelial growth factor levels in cancer patientsQ42516923
Zoledronate Stimulates γδ T Cells in Prostate Cancer PatientsQ42948400
Enhanced ability of dendritic cells to stimulate innate and adaptive immunity on short-term incubation with zoledronic acidQ44020395
Novel antiangiogenic effects of the bisphosphonate compound zoledronic acidQ44106382
Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastasesQ44202473
The pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with varying degrees of renal functionQ44343595
Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial--the Zoledronic Acid Lung Cancer and Other Solid Tumors Study GroupQ44547450
Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trialQ44611376
Long-term efficacy and safety of zoledronic acid in the treatment of skeletal metastases in patients with nonsmall cell lung carcinoma and other solid tumors: a randomized, Phase III, double-blind, placebo-controlled trialQ44937090
Clinical and immunological evaluation of zoledronate-activated Vgamma9gammadelta T-cell-based immunotherapy for patients with multiple myeloma.Q46028184
Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudyQ46417627
Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer.Q46434787
Differential effect of doxorubicin and zoledronic acid on intraosseous versus extraosseous breast tumor growth in vivo.Q46482917
Effective inhibition of aromatase inhibitor-associated bone loss by zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: ZO-FAST Study results.Q46801197
Antitumor effects of clinical dosing regimens of bisphosphonates in experimental breast cancer bone metastasis.Q50696322
Nitrogen-containing bisphosphonates can inhibit angiogenesis in vivo without the involvement of farnesyl pyrophosphate synthaseQ54976416
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
P304page(s)911-918
P577publication date2011-05-13
P1433published inExpert Opinion on Drug Metabolism & ToxicologyQ5421205
P1476titlePharmacokinetic evaluation of zoledronic acid
P478volume7

Reverse relations

cites work (P2860)
Q37993568Bisphosphonate related osteonecrosis of the jaws: a review
Q53743085Models for anti-tumor activity of bisphosphonates using refined topochemical descriptors.
Q37577433Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.
Q35919801Urinary N telopeptide levels in predicting the anti-nociceptive responses of zoledronic acid and paclitaxel in a rat model of bone metastases
Q36395911Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB

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