| scholarly article | Q13442814 |
| P356 | DOI | 10.2174/1874091X01105010009 |
| P724 | Internet Archive ID | pubmed-PMC3104551 |
| P932 | PMC publication ID | 3104551 |
| P698 | PubMed publication ID | 21633666 |
| P2093 | author name string | Yang Zhang | |
| Mark Richter | |||
| Ambrish Roy | |||
| Carolyn A Rankin | |||
| P2860 | cites work | Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions | Q22010047 |
| TRIADs: a new class of proteins with a novel cysteine-rich signature | Q22010435 | ||
| Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase | Q22254584 | ||
| Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity | Q24290192 | ||
| Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1 | Q24290518 | ||
| The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins | Q24290709 | ||
| An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin | Q24291412 | ||
| Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease | Q24291767 | ||
| Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity | Q24297369 | ||
| Parkin ubiquitinates and promotes the degradation of RanBP2 | Q24298223 | ||
| Structure of the C-terminal RING finger from a RING-IBR-RING/TRIAD motif reveals a novel zinc-binding domain distinct from a RING | Q24298636 | ||
| CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity | Q24302505 | ||
| Parkin accumulation in aggresomes due to proteasome impairment | Q24308757 | ||
| Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism | Q24309753 | ||
| Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation | Q24312713 | ||
| BAG5 inhibits parkin and enhances dopaminergic neuron degeneration | Q24322908 | ||
| Recognition of the polyubiquitin proteolytic signal | Q24530006 | ||
| Control of biochemical reactions through supramolecular RING domain self-assembly | Q24539123 | ||
| Identification and preliminary characterization of a protein motif related to the zinc finger | Q24563322 | ||
| LOMETS: a local meta-threading-server for protein structure prediction | Q24682449 | ||
| Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain | Q27640694 | ||
| Structure of the Parkin in-between-ring domain provides insights for E3-ligase dysfunction in autosomal recessive Parkinson's disease | Q27644069 | ||
| Crystal structure and molecular dynamics simulation of ubiquitin-like domain of murine parkin | Q27650635 | ||
| RING domain E3 ubiquitin ligases | Q27860546 | ||
| GROMACS: fast, flexible, and free | Q27860998 | ||
| A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. | Q27935265 | ||
| Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease | Q43735682 | ||
| Aggresome-related biogenesis of Lewy bodies | Q44242992 | ||
| The C289G and C418R missense mutations cause rapid sequestration of human Parkin into insoluble aggregates | Q44695541 | ||
| Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains | Q45271574 | ||
| Effects of partial suppression of parkin on huntingtin mutant R6/1 mice. | Q45293924 | ||
| Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function | Q46797053 | ||
| A disease state mutation unfolds the parkin ubiquitin-like domain. | Q46898944 | ||
| Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene | Q48398668 | ||
| Parkin: a multifaceted ubiquitin ligase. | Q51116287 | ||
| Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. | Q51387140 | ||
| Regulation of DNA repair by parkin. | Q51769493 | ||
| Aberrant Folding of Pathogenic Parkin Mutants | Q60290972 | ||
| One ring to rule a superfamily of E3 ubiquitin ligases | Q77752816 | ||
| Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro | Q81597727 | ||
| The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI | Q28114820 | ||
| 14-3-3eta is a novel regulator of parkin ubiquitin ligase | Q28115387 | ||
| Zinc fingers--folds for many occasions | Q28187358 | ||
| SEPT5_v2 is a parkin-binding protein | Q28209755 | ||
| PDZ domains and the organization of supramolecular complexes | Q28209906 | ||
| CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation | Q28216253 | ||
| S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function | Q28258212 | ||
| Parkin interacts with the proteasome subunit alpha4 | Q28259006 | ||
| The RING finger domain: a recent example of a sequence-structure family | Q28289644 | ||
| Aggresomes: a cellular response to misfolded proteins | Q28292275 | ||
| Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6 | Q28397050 | ||
| DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase | Q28513159 | ||
| Parkin binds to alpha/beta tubulin and increases their ubiquitination and degradation | Q28572388 | ||
| Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain | Q28573608 | ||
| Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress | Q28579526 | ||
| The septin CDCrel-1 is dispensable for normal development and neurotransmitter release | Q28589423 | ||
| The Hsp70 and Hsp60 chaperone machines | Q29547601 | ||
| The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses | Q29615239 | ||
| Aggresomes, inclusion bodies and protein aggregation | Q29615253 | ||
| The PINK1/Parkin pathway regulates mitochondrial morphology | Q29615641 | ||
| Association between early-onset Parkinson's disease and mutations in the parkin gene | Q29615733 | ||
| Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin | Q29622838 | ||
| Posttranslational quality control: folding, refolding, and degrading proteins. | Q30323825 | ||
| Zinc coordination sphere in biochemical zinc sites. | Q30329554 | ||
| Local energy landscape flattening: parallel hyperbolic Monte Carlo sampling of protein folding. | Q30331169 | ||
| REMO: A new protocol to refine full atomic protein models from C-alpha traces by optimizing hydrogen-bonding networks | Q30375449 | ||
| Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity | Q30448692 | ||
| E3 ubiquitin-protein ligase activity of Parkin is dependent on cooperative interaction of RING finger (TRIAD) elements | Q30713868 | ||
| A tryptophan-containing open-chain framework for tuning a high selectivity for Ca2+ and 13C NMR observation of a Ca2+-indole interaction in aqueous solution | Q30984405 | ||
| Parkin reverses intracellular beta-amyloid accumulation and its negative effects on proteasome function. | Q33749114 | ||
| RING domains: master builders of molecular scaffolds? | Q33827485 | ||
| Self-assembly properties of a model RING domain | Q33894328 | ||
| The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. | Q34202584 | ||
| How much phenotypic variation can be attributed to parkin genotype? | Q34218728 | ||
| SPICKER: a clustering approach to identify near-native protein folds | Q34304367 | ||
| ??? | Q64860635 | ||
| Screening for mutations in synaptotagmin XI in Parkinson's disease. | Q34346583 | ||
| Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity | Q34528753 | ||
| Nucleocytoplasmic transport: taking an inventory | Q35541034 | ||
| The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity | Q35610627 | ||
| Physical mechanisms and biological significance of supramolecular protein self-assembly. | Q35743754 | ||
| Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies | Q35748069 | ||
| Lewy-body formation is an aggresome-related process: a hypothesis | Q35840040 | ||
| Ubiquitin, proteasome and parkin | Q35967578 | ||
| Ubiquitination | Q36467132 | ||
| Parkin and defective ubiquitination in Parkinson's disease | Q36611521 | ||
| The ring between ring fingers (RBR) protein family | Q36762636 | ||
| Regulation of mitochondrial fusion and division | Q36980993 | ||
| Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway. | Q37003169 | ||
| Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation | Q37081948 | ||
| Direct binding with histone deacetylase 6 mediates the reversible recruitment of parkin to the centrosome | Q37187912 | ||
| Autophagy-mediated clearance of aggresomes is not a universal phenomenon | Q37294767 | ||
| Emerging pathways in genetic Parkinson's disease: autosomal-recessive genes in Parkinson's disease--a common pathway? | Q37330543 | ||
| Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions | Q39806585 | ||
| DNA damage induces nuclear translocation of parkin | Q39823990 | ||
| Parkin promotes intracellular Abeta1-42 clearance | Q39844881 | ||
| Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations | Q40165324 | ||
| Functional modulation of parkin through physical interaction with SUMO-1. | Q40235074 | ||
| Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases | Q40408101 | ||
| Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition | Q40422333 | ||
| Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations | Q40437542 | ||
| Parkin stabilizes microtubules through strong binding mediated by three independent domains. | Q40452676 | ||
| Pathogenic mutations inactivate parkin by distinct mechanisms. | Q40479590 | ||
| Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity | Q40489168 | ||
| RING finger 1 mutations in Parkin produce altered localization of the protein | Q40629977 | ||
| Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones | Q40634794 | ||
| Parkin is not regulated by the unfolded protein response in human neuroblastoma cells | Q40657291 | ||
| Parkin facilitates the elimination of expanded polyglutamine proteins and leads to preservation of proteasome function. | Q40658225 | ||
| Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease | Q40795664 | ||
| The RING finger. A novel protein sequence motif related to the zinc finger. | Q40818998 | ||
| Comparative genomics of the RBR family, including the Parkinson's disease-related gene parkin and the genes of the ariadne subfamily | Q42049727 | ||
| Parkin is recruited to the centrosome in response to inhibition of proteasomes | Q42798009 | ||
| Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin. | Q43123357 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 9-26 | |
| P577 | publication date | 2011-04-18 | |
| P1433 | published in | The Open Biochemistry Journal | Q27722043 |
| P1476 | title | Parkin, A Top Level Manager in the Cell's Sanitation Department | |
| P478 | volume | 5 |
| Q36726882 | Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson's Disease Patients. |
| Q34197058 | Following Ariadne's thread: a new perspective on RBR ubiquitin ligases |
| Q30452210 | Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target |
| Q41874714 | Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. |
| Q38004927 | Regulation of Parkin E3 ubiquitin ligase activity. |
| Q34230329 | Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation. |
| Q24339442 | Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection |
| Q27678625 | Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases |
| Q48266360 | TCDD induces UbcH7 expression and synphilin-1 protein degradation in the mouse ventral midbrain. |
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