| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1038/ONC.2011.220 |
| P698 | PubMed publication ID | 21666712 |
| P2093 | author name string | R T Abraham | |
| C H Eng | |||
| P2860 | cites work | Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes | Q44650510 |
| p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation | Q45345446 | ||
| A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress. | Q46272227 | ||
| GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation. | Q50681145 | ||
| Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. | Q53530417 | ||
| Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. | Q53597468 | ||
| Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3 | Q56777123 | ||
| Mammalian target of rapamycin as a therapeutic target in oncology | Q80521836 | ||
| Autophagy in Ras-induced malignant transformation: fatal or vital? | Q83806883 | ||
| Nix is a selective autophagy receptor for mitochondrial clearance | Q22001532 | ||
| Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids | Q24306330 | ||
| The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy | Q24307759 | ||
| Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy | Q24310301 | ||
| A role for NBR1 in autophagosomal degradation of ubiquitinated substrates | Q24316135 | ||
| Parkin is recruited selectively to impaired mitochondria and promotes their autophagy | Q24317471 | ||
| Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex | Q24559347 | ||
| Fatty acid synthesis: a potential selective target for antineoplastic therapy | Q24561903 | ||
| Understanding the Warburg effect: the metabolic requirements of cell proliferation | Q24604760 | ||
| Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment | Q24611183 | ||
| Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene | Q24617547 | ||
| Modulation of intracellular ROS levels by TIGAR controls autophagy | Q24644257 | ||
| HIF-1: upstream and downstream of cancer metabolism | Q24647482 | ||
| Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells | Q24648994 | ||
| ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery | Q24649645 | ||
| Autophagy suppresses tumorigenesis through elimination of p62 | Q24650670 | ||
| Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 | Q24670840 | ||
| Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains | Q28114920 | ||
| TIGAR, a p53-inducible regulator of glycolysis and apoptosis | Q28118306 | ||
| Induction of autophagy and inhibition of tumorigenesis by beclin 1 | Q28131718 | ||
| Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21 | Q28138953 | ||
| p53 regulates mitochondrial respiration | Q28242400 | ||
| The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond | Q28278349 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| c-myc Repression of TSC2 contributes to control of translation initiation and Myc-induced transformation | Q28573044 | ||
| Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia | Q28586744 | ||
| Autophagy in infection | Q28752279 | ||
| The biology of cancer: metabolic reprogramming fuels cell growth and proliferation | Q29547301 | ||
| Autophagy regulates lipid metabolism | Q29547421 | ||
| Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells | Q29614181 | ||
| Essential role for Nix in autophagic maturation of erythroid cells | Q29614480 | ||
| FoxO3 controls autophagy in skeletal muscle in vivo | Q29614483 | ||
| Autophagy, not apoptosis, is essential for midgut cell death in Drosophila | Q37438206 | ||
| MYC-induced cancer cell energy metabolism and therapeutic opportunities | Q37438881 | ||
| Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies | Q37616407 | ||
| Autophagy and tumorigenesis | Q37662807 | ||
| Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes | Q37689294 | ||
| Autophagy and Crohn's disease: at the crossroads of infection, inflammation, immunity, and cancer | Q37764367 | ||
| Tumor-host interactions: a far-reaching relationship | Q37774174 | ||
| Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night | Q37831538 | ||
| Glutaminolysis yields a metabolic by-product that stimulates autophagy | Q39665424 | ||
| A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions | Q39680852 | ||
| MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy | Q39796361 | ||
| Autophagy is required during cycling hypoxia to lower production of reactive oxygen species | Q39823606 | ||
| Glycolytic flux signals to mTOR through glyceraldehyde-3-phosphate dehydrogenase-mediated regulation of Rheb | Q39849826 | ||
| Superoxide is the major reactive oxygen species regulating autophagy | Q39858156 | ||
| NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy | Q40253038 | ||
| Ras transformation requires metabolic control by 6-phosphofructo-2-kinase | Q40277185 | ||
| The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway | Q40789651 | ||
| Leucine limitation induces autophagy and activation of lysosome-dependent proteolysis in C2C12 myotubes through a mammalian target of rapamycin-independent signaling pathway | Q40868615 | ||
| Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila | Q41913649 | ||
| Novel targets for Huntington's disease in an mTOR-independent autophagy pathway | Q41978909 | ||
| Mantle skewness and ridge segmentation | Q41996834 | ||
| Autophagy-deficient mice develop multiple liver tumors | Q42099409 | ||
| Lysosomal positioning coordinates cellular nutrient responses. | Q42160015 | ||
| Ammonia derived from glutaminolysis is a diffusible regulator of autophagy | Q42470786 | ||
| K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts | Q42812919 | ||
| Ras is involved in the negative control of autophagy through the class I PI3-kinase | Q42830028 | ||
| An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1 | Q29614563 | ||
| Autophagic cell death: the story of a misnomer | Q29614564 | ||
| Ras, PI(3)K and mTOR signalling controls tumour cell growth | Q29614734 | ||
| Autophagy gone awry in neurodegenerative diseases | Q29614849 | ||
| Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy | Q29615616 | ||
| Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis | Q29615683 | ||
| Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity | Q29616651 | ||
| Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction | Q29616653 | ||
| c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism | Q29617213 | ||
| Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis | Q29617613 | ||
| Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis | Q29617725 | ||
| Akt stimulates aerobic glycolysis in cancer cells | Q29619301 | ||
| Pancreatic cancers require autophagy for tumor growth | Q29620331 | ||
| Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents? | Q31085526 | ||
| Small molecule regulators of autophagy identified by an image-based high-throughput screen | Q33306309 | ||
| Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts | Q33415058 | ||
| The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. | Q33559643 | ||
| A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy | Q33642615 | ||
| Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway | Q33718319 | ||
| ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS | Q33733064 | ||
| The association of AMPK with ULK1 regulates autophagy | Q33745164 | ||
| A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases | Q33789567 | ||
| Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases. | Q33799555 | ||
| Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation | Q34489861 | ||
| Autophagic programmed cell death by selective catalase degradation | Q34596715 | ||
| Macroautophagy regulates energy metabolism during effector T cell activation | Q34615092 | ||
| Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells | Q34619590 | ||
| Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. | Q34626231 | ||
| Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. | Q34626763 | ||
| Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells. | Q34645070 | ||
| Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation | Q34787032 | ||
| Principles and current strategies for targeting autophagy for cancer treatment | Q34787732 | ||
| Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells | Q34979866 | ||
| Autophagy suppresses tumor progression by limiting chromosomal instability | Q35812219 | ||
| Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis | Q35855667 | ||
| Fuel feeds function: energy metabolism and the T-cell response | Q36292868 | ||
| Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation | Q36835194 | ||
| Glutamine increases autophagy under Basal and stressed conditions in intestinal epithelial cells | Q37171062 | ||
| P433 | issue | 47 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | autophagy | Q288322 |
| P304 | page(s) | 4687-4696 | |
| P577 | publication date | 2011-06-13 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming | |
| P478 | volume | 30 |
| Q48275859 | AKT/GSK3β-dependent autophagy contributes to the neuroprotection of limb remote ischemic postconditioning in the transient cerebral ischemic rat model. |
| Q28546534 | AMDE-1 is a dual function chemical for autophagy activation and inhibition |
| Q38816145 | Arginine dependence of tumor cells: targeting a chink in cancer's armor |
| Q91753411 | Association of Autophagy Gene ATG16L1 Polymorphism with Human Prostate Cancer and Bladder Cancer in Turkish Population |
| Q24294545 | Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk |
| Q38846752 | Autophagy inhibition enhances isorhamnetin‑induced mitochondria‑dependent apoptosis in non‑small cell lung cancer cells |
| Q47135389 | Autophagy mediates free fatty acid effects on MDA-MB-231 cell proliferation, migration and invasion |
| Q27025391 | Autophagy modulation as a target for anticancer drug discovery |
| Q41479076 | Autophagy regulates cytoplasmic remodeling during cell reprogramming in a zebrafish model of muscle regeneration. |
| Q39438867 | Autophagy-mediated HMGB1 release antagonizes apoptosis of gastric cancer cells induced by vincristine via transcriptional regulation of Mcl-1. |
| Q36926125 | Autophagy-related gene 12 (ATG12) is a novel determinant of primary resistance to HER2-targeted therapies: utility of transcriptome analysis of the autophagy interactome to guide breast cancer treatment |
| Q40140848 | Bacteroides fragilis Enterotoxin Induces Formation of Autophagosomes in Endothelial Cells but Interferes with Fusion with Lysosomes for Complete Autophagic Flux through a Mitogen-Activated Protein Kinase-, AP-1-, and C/EBP Homologous Protein-Depende |
| Q42292338 | Benzyl isothiocyanate induces reactive oxygen species-initiated autophagy and apoptosis in human prostate cancer cells |
| Q41260202 | Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a. |
| Q36111779 | Glutaminolysis and autophagy in cancer |
| Q54354000 | Hypoxia-regulated gene network in drug resistance and cancer progression. |
| Q28082347 | Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy |
| Q47141550 | Metabolic re-patterning in COPD airway smooth muscle cells |
| Q47653685 | Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson's disease |
| Q38031895 | Novel pharmacological modulators of autophagy and therapeutic prospects |
| Q35864136 | Novel therapies in glioblastoma |
| Q47116681 | Panax notoginseng saponins mitigate cisplatin induced nephrotoxicity by inducing mitophagy via HIF-1α. |
| Q34916951 | Post-translational control of IL-1β via the human papillomavirus type 16 E6 oncoprotein: a novel mechanism of innate immune escape mediated by the E3-ubiquitin ligase E6-AP and p53. |
| Q42514979 | Proteomics Insights into Autophagy. |
| Q43083254 | Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis |
| Q93163927 | Role of purines in regulation of metabolic reprogramming |
| Q36625697 | Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma |
| Q38082328 | Senescence and aging: the critical roles of p53. |
| Q37628979 | Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy |
| Q38847322 | Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice. |
| Q58919591 | Targeting Oncogene-Induced Autophagy: A New Approach in Cancer Therapy? |
| Q36210184 | The Histone Deacetylase Gene Rpd3 Is Required for Starvation Stress Resistance |
| Q41885196 | The TBC/RabGAP Armus coordinates Rac1 and Rab7 functions during autophagy. |
| Q35393206 | The dynamic nature of autophagy in cancer |
| Q26775232 | The fate of chemoresistance in triple negative breast cancer (TNBC) |
| Q37945272 | The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy. |
| Q28390139 | The role of hypoxia-inducible factor-1α in zinc oxide nanoparticle-induced nephrotoxicity in vitro and in vivo |
| Q37323077 | Tumour hypoxia determines the potential of combining mTOR and autophagy inhibitors to treat mammary tumours. |
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