scholarly article | Q13442814 |
P50 | author | Mizushima Noboru | Q15055172 |
P2093 | author name string | Naoyuki Yamada | |
Shun-ichiro Iemura | |||
Takeshi Kaizuka | |||
Tohru Natsume | |||
Jun-Lin Guan | |||
Yutaka Miura | |||
Taichi Hara | |||
Kenji Takehana | |||
Chieko Kishi | |||
Akito Takamura | |||
Nao Hosokawa | |||
Noriko Oshiro | |||
P2860 | cites work | PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase | Q24300915 |
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes | Q24301020 | ||
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action | Q24302566 | ||
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy | Q24314616 | ||
Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism | Q24329236 | ||
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy | Q24523548 | ||
Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle | Q24534914 | ||
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation | Q24535862 | ||
The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1 | Q24634783 | ||
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells | Q24648105 | ||
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery | Q24649645 | ||
Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways | Q24682845 | ||
Tor-mediated induction of autophagy via an Apg1 protein kinase complex | Q24685670 | ||
Autophagy in the Pathogenesis of Disease | Q27860558 | ||
TOR signaling in growth and metabolism | Q27860757 | ||
Autophagy fights disease through cellular self-digestion | Q27860902 | ||
Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae | Q27930610 | ||
Hierarchy of Atg proteins in pre-autophagosomal structure organization | Q27931408 | ||
Atg17 regulates the magnitude of the autophagic response | Q27932508 | ||
Characterization of a novel autophagy-specific gene, ATG29. | Q27935122 | ||
Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae | Q27938390 | ||
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast | Q27939948 | ||
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast | Q28131604 | ||
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate | Q28187453 | ||
Defining the role of mTOR in cancer | Q28235431 | ||
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease | Q28261987 | ||
Autophagy and signaling: their role in cell survival and cell death | Q28278893 | ||
Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking | Q28289648 | ||
Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51 | Q28512062 | ||
A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons | Q28512257 | ||
Autophagy: process and function | Q29547296 | ||
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death | Q29547297 | ||
Autophagy: from phenomenology to molecular understanding in less than a decade | Q29614174 | ||
How to interpret LC3 immunoblotting | Q29614175 | ||
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG | Q29614477 | ||
Role and regulation of starvation-induced autophagy in the Drosophila fat body | Q29617035 | ||
Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains | Q33879860 | ||
Lithium induces autophagy by inhibiting inositol monophosphatase | Q36321015 | ||
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae | Q36438806 | ||
FIP200, a key signaling node to coordinately regulate various cellular processes | Q36515638 | ||
Signalling and autophagy regulation in health, aging and disease | Q36594286 | ||
Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation | Q36835194 | ||
Expanding mTOR signaling | Q36902840 | ||
Unveiling the roles of autophagy in innate and adaptive immunity | Q36927499 | ||
An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation | Q37146685 | ||
LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization | Q40154056 | ||
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy | Q40250473 | ||
Characterization of the phosphoproteins and protein kinase activity in mTOR immunoprecipitates. | Q40993000 | ||
Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size | Q47339876 | ||
Autophagy is essential for preimplantation development of mouse embryos | Q48745730 | ||
Autophagy and p70S6 kinase. | Q52670758 | ||
Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae | Q57274142 | ||
A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics | Q78287803 | ||
ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes | Q79495023 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Autophagy related 13 | Q4826898 |
cell biology | Q7141 | ||
autophagy | Q288322 | ||
Atg1/ULK1 kinase complex | Q21106564 | ||
Regulatory associated protein of MTOR complex 1 | Q21115067 | ||
RB1 inducible coiled-coil 1 | Q21115135 | ||
Unc-51 like autophagy activating kinase 1 | Q21116760 | ||
RB1-inducible coiled-coil 1 | Q21494756 | ||
Unc-51 like kinase 1 | Q21495318 | ||
Autophagy related 13 | Q21499122 | ||
P304 | page(s) | 1981-91 | |
P577 | publication date | 2009-04-01 | |
P1433 | published in | Molecular Biology of the Cell | Q2338259 |
P1476 | title | Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy | |
P478 | volume | 20 |
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Q92734145 | Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy |
Q39837169 | Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. |
Q33619407 | Dennd3 functions as a guanine nucleotide exchange factor for small GTPase Rab12 in mouse embryonic fibroblasts |
Q27311286 | Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy |
Q51743936 | Differential effects of overexpression of Rab5 and Rab22 on autophagy in PC12 cells with or without NGF. |
Q47430428 | Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets. |
Q41479009 | Diminished MTORC1-Dependent JNK Activation Underlies the Neurodevelopmental Defects Associated with Lysosomal Dysfunction |
Q50307310 | Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes |
Q34630595 | Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest |
Q39802272 | Distinct functions of Ulk1 and Ulk2 in the regulation of lipid metabolism in adipocytes |
Q36783033 | Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model |
Q35871496 | Divergent roles of BECN1 in LC3 lipidation and autophagosomal function |
Q37107138 | Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging |
Q36581153 | Drosophila as a model system to study autophagy |
Q38799222 | Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis |
Q33796255 | Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase |
Q36445102 | Dual role of autophagy in HIV-1 replication and pathogenesis |
Q42321600 | Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer |
Q64074440 | Dynamic Regulation of Proteasome Expression |
Q29620685 | Dynamics and diversity in autophagy mechanisms: lessons from yeast |
Q38171032 | EGFR signaling and autophagy dependence for growth, survival, and therapy resistance |
Q90746115 | ER-to-lysosome-associated degradation of proteasome-resistant ATZ polymers occurs via receptor-mediated vesicular transport |
Q28568875 | Early and sustained activation of autophagy in degenerating axons after spinal cord injury |
Q38144264 | Early signalling events of autophagy |
Q27005828 | Eaten alive: novel insights into autophagy from multicellular model systems |
Q99370886 | Eating the unknown: Xenophagy and ER-phagy are cytoprotective defenses against pathogens |
Q37859076 | Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease |
Q36473735 | Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway |
Q59757762 | Elucidating TOR Signaling in Chlamydomonas reinhardtii |
Q36194753 | Emerging role of autophagy in kidney function, diseases and aging |
Q39349204 | Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine a-induced cell death |
Q36111664 | Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. |
Q50090100 | Everolimus Plus Ku0063794 Regimen Promotes Anticancer Effects against Hepatocellular Carcinoma Cells through the Paradoxical Inhibition of Autophagy |
Q34204391 | Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women |
Q39420503 | Exercise-mediated modulation of autophagy in skeletal muscle. |
Q49886956 | Exploiting cancer vulnerabilities: mTOR, autophagy, and homeostatic imbalance |
Q41504464 | Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells |
Q38985509 | FIP200 is involved in murine pseudomonas infection by regulating HMGB1 intracellular translocation |
Q35876573 | FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells |
Q24314938 | FIP200 regulates targeting of Atg16L1 to the isolation membrane |
Q24302037 | FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation |
Q26851722 | FOXO transcription factors: key regulators of cellular quality control |
Q28243647 | Fighting neurodegeneration with rapamycin: mechanistic insights |
Q100750514 | Fine-tuning of AMPK-ULK1-mTORC1 regulatory triangle is crucial for autophagy oscillation |
Q36181637 | Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose |
Q56877965 | Flaviviruses and Autophagy |
Q41169445 | Foot-and-mouth disease virus induces autophagosomes during cell entry via a class III phosphatidylinositol 3-kinase-independent pathway |
Q35014198 | Frontier of epilepsy research - mTOR signaling pathway |
Q35632729 | Functions of autophagy in pathological cardiac hypertrophy |
Q28548356 | G9a Inhibition Induces Autophagic Cell Death via AMPK/mTOR Pathway in Bladder Transitional Cell Carcinoma |
Q39357584 | GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy |
Q38837034 | GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling |
Q64061443 | Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation |
Q28067399 | Glioblastoma, hypoxia and autophagy: a survival-prone 'ménage-à-trois' |
Q35812645 | Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells |
Q38112382 | Growth or longevity: the TOR's decision on lifespan regulation |
Q21996341 | Guidelines for the use and interpretation of assays for monitoring autophagy |
Q22676705 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) |
Q26996778 | HCV and Oxidative Stress: Implications for HCV Life Cycle and HCV-Associated Pathogenesis |
Q35858374 | HCV core protein represses the apoptosis and improves the autophagy of human hepatocytes |
Q49888642 | HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution. |
Q39241528 | Hepatitis C virus inhibits AKT-tuberous sclerosis complex (TSC), the mechanistic target of rapamycin (MTOR) pathway, through endoplasmic reticulum stress to induce autophagy |
Q34924245 | Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy |
Q47664663 | High LC3/Beclin Expression Correlates with Poor Survival in Glioma: a Definitive Role for Autophagy as Evidenced by In Vitro Autophagic Flux |
Q48265458 | High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1. |
Q35944301 | High expression levels of unc-51-like kinase 1 as a predictor of poor prognosis in colorectal cancer |
Q35852901 | Histone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways. |
Q37977162 | How phosphoinositide 3-phosphate controls growth downstream of amino acids and autophagy downstream of amino acid withdrawal |
Q24323790 | Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagy |
Q38829905 | Hydrogen sulfide reduces serum triglyceride by activating liver autophagy via the AMPK-mTOR pathway |
Q60934682 | Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy |
Q39577630 | Hypothalamic lipophagy and energetic balance |
Q41107802 | Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation. |
Q38772023 | Hypoxia and cellular metabolism in tumour pathophysiology |
Q37614300 | IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells |
Q47214959 | IL4 (interleukin 4) induces autophagy in B cells leading to exacerbated asthma |
Q30498183 | Identification of PTPsigma as an autophagic phosphatase. |
Q33878961 | Identification of a novel MTOR activator and discovery of a competing endogenous RNA regulating autophagy in vascular endothelial cells |
Q37376186 | Identification of nasopharyngeal carcinoma metastasis-related biomarkers by iTRAQ combined with 2D-LC-MS/MS. |
Q36389858 | Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses |
Q47104731 | Implications of aging and the endoplasmic reticulum unfolded protein response on the molecular modality of breast cancer. |
Q37834371 | Implications of autophagy for glomerular aging and disease |
Q48563627 | In Silico HTS and Structure Based Optimization of Indazole-Derived ULK1 Inhibitors. |
Q36621704 | In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line. |
Q89957921 | Increased autophagy/mitophagy levels in primary tumours of patients with pancreatic neuroendocrine neoplasms |
Q36808210 | Induction of autophagy by valproic acid enhanced lymphoma cell chemosensitivity through HDAC-independent and IP3-mediated PRKAA activation |
Q41768449 | Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation |
Q64107126 | Influence of Normal Aging on Brain Autophagy: A Complex Scenario |
Q60954913 | Influenza A Virus NS1 Protein Suppresses JNK1-Dependent Autophagosome Formation Mediated by Rab11a Recycling Endosomes |
Q42108388 | Inhibition of PI3K/Akt/mTOR signaling by natural products |
Q38795848 | Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells |
Q39326047 | Inhibition of mTOR kinase as a therapeutic target for acute myeloid leukemia |
Q43182570 | Inhibition of target of rapamycin signaling and stress activate autophagy in Chlamydomonas reinhardtii |
Q90198375 | Insulin-induced de novo lipid synthesis occurs mainly via mTOR-dependent regulation of proteostasis of SREBP-1c |
Q34313770 | Integration of Clearance Mechanisms: The Proteasome and Autophagy |
Q39553486 | Intensive expression of UNC-51-like kinase 1 is a novel biomarker of poor prognosis in patients with esophageal squamous cell carcinoma |
Q92875825 | Interactions between Autophagy and DNA Viruses |
Q26745577 | Interactions between Autophagy and Inhibitory Cytokines |
Q39419450 | Interplay between Autophagy, Exosomes and HIV-1 Associated Neurological Disorders: New Insights for Diagnosis and Therapeutic Applications |
Q37205898 | Intestinal epithelium and autophagy: partners in gut homeostasis |
Q42516357 | Ion channels in the regulation of autophagy |
Q47108927 | Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease? |
Q28071388 | Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives |
Q59085556 | KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing |
Q92376588 | Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis |
Q28830062 | Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells |
Q38931119 | LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells |
Q47895048 | LC3-Associated Phagocytosis and Inflammation. |
Q28118644 | La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1) |
Q42085847 | Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy |
Q26866321 | Leucine and mTORC1: a complex relationship |
Q51590526 | Leucine restores murine hepatic triglyceride accumulation induced by a low-protein diet by suppressing autophagy and excessive endoplasmic reticulum stress. |
Q38872712 | Lipids, lysosomes, and autophagy. |
Q38015814 | Liver autophagy: physiology and pathology |
Q98163537 | LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes |
Q58000904 | Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells |
Q92039543 | Loss of BRUCE reduces cellular energy level and induces autophagy by driving activation of the AMPK-ULK1 autophagic initiating axis |
Q36193081 | Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells |
Q41818511 | Loss of the starvation-induced gene Rack1 leads to glycogen deficiency and impaired autophagic responses in Drosophila |
Q95288907 | Low FoxO expression in Drosophila somatosensory neurons protects dendrite growth under nutrient restriction |
Q36357766 | Lymphangioleiomyomatosis - a wolf in sheep's clothing. |
Q48121086 | Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes. |
Q40970806 | Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R |
Q83771997 | Lysosome positioning coordinates mTORC1 activity and autophagy |
Q91452379 | Lysosomes as dynamic regulators of cell and organismal homeostasis |
Q57168286 | MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process |
Q57021003 | MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress |
Q34552915 | MODULATION OF AUTOPHAGY AND ITS POTENTIAL FOR CANCER THERAPY. |
Q57795695 | MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca communication: a dead end in cancer cells |
Q47820387 | MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling |
Q50286485 | MTORC1 dissociates from ULK complex |
Q30524356 | MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB. |
Q34999109 | Macronutrient composition of the diet affects the feeding-mediated down regulation of autophagy in muscle of rainbow trout (O. mykiss). |
Q38189969 | Making new contacts: the mTOR network in metabolism and signalling crosstalk |
Q91650616 | Mammalian Mitophagosome Formation: A Focus on the Early Signals and Steps |
Q24595447 | Mammalian autophagy: core molecular machinery and signaling regulation |
Q37491912 | Mammalian macroautophagy at a glance |
Q39104277 | Mammalian target of rapamycin (mTOR): a central regulator of male fertility? |
Q35107703 | Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy |
Q35157985 | Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders |
Q35696469 | Mapping autophagy on to your metabolic radar |
Q37736362 | Mapping sites of aspirin-induced acetylations in live cells by quantitative acid-cleavable activity-based protein profiling (QA-ABPP). |
Q38260329 | Mechanism and Regulation of Autophagy and Its Role in Neuronal Diseases |
Q57269850 | Mechanism and medical implications of mammalian autophagy |
Q38159574 | Mechanism and physiological significance of growth factor-related autophagy. |
Q94554949 | Mechanisms governing autophagosome biogenesis |
Q39182119 | Mechanisms of Autophagy Initiation |
Q37217474 | Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin. |
Q38104492 | Mechanistic / mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia |
Q37974949 | Membrane recruitment of autophagy proteins in selective autophagy |
Q60949979 | Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway |
Q50217787 | Metabolic Regulation of T Cell Immunity |
Q38040587 | Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review |
Q37620679 | Metabolism addiction in pancreatic cancer |
Q29547276 | Methods in mammalian autophagy research |
Q90249849 | MicroRNA-29 enhances autophagy and cleanses exogenous mutant αB-crystallin in retinal pigment epithelial cells |
Q38336639 | Minireview: Autophagy in pancreatic β-cells and its implication in diabetes |
Q40895675 | Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy |
Q64360970 | MoSnt2-dependent deacetylation of histone H3 mediates MoTor-dependent autophagy and plant infection by the rice blast fungus Magnaporthe oryzae |
Q33665207 | Molecular Pathways: Increased Susceptibility to Infection Is a Complication of mTOR Inhibitor Use in Cancer Therapy |
Q38921302 | Molecular mechanism of hepatic steatosis: pathophysiological role of autophagy |
Q30278688 | Molecular mechanisms for mitochondrial adaptation to exercise training in skeletal muscle |
Q35037307 | Molecular mechanisms of autophagy in the cardiovascular system |
Q38866763 | Molecular mechanisms of mTOR regulation by stress |
Q38100537 | Molecular signaling toward mitophagy and its physiological significance. |
Q92608420 | Monitoring stress-induced autophagic engulfment and degradation of the 26S proteasome in mammalian cells |
Q28854564 | Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator |
Q40386133 | Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition |
Q28119201 | Nedd4 E3 ubiquitin ligase promotes cell proliferation and autophagy |
Q37791832 | Negative regulation of autophagy |
Q38122158 | Neural plasticity and proliferation in the generation of antidepressant effects: hippocampal implication. |
Q33661680 | Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration |
Q37869692 | Neuronal autophagy as a mediator of life and death: contrasting roles in chronic neurodegenerative and acute neural disorders |
Q38042565 | Neuronal autophagy in cerebral ischemia |
Q33775384 | Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain. |
Q48506350 | New Insights Into the Role of mTOR Signaling in the Cardiovascular System. |
Q57464348 | New Mammalian Target of Rapamycin (mTOR) Modulators Derived from Natural Product Databases and Marine Extracts by Using Molecular Docking Techniques |
Q37524096 | New autophagy reporter mice reveal dynamics of proximal tubular autophagy |
Q42738918 | Noboru Mizushima: All about autophagy. Interview by Caitlin Sedwick |
Q28728348 | Non-canonical functions of the tuberous sclerosis complex-Rheb signalling axis |
Q37323116 | Normalizing translation through 4E-BP prevents mTOR-driven cortical mislamination and ameliorates aberrant neuron integration. |
Q38424856 | Novel Insights into Osteoarthritis Joint Pathology from Studies in Mice. |
Q38914171 | Novel pharmacological modulators of autophagy: an updated patent review (2012-2015). |
Q33756641 | Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis |
Q34331244 | Nutrient signaling to mTOR and cell growth |
Q34720900 | Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK. |
Q37008888 | Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals |
Q42152336 | O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation |
Q37636778 | O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity |
Q89977010 | Oral Microbes and Mucosal Dendritic Cells, "Spark and Flame" of Local and Distant Inflammatory Diseases |
Q36223627 | Orchestrated Action of PP2A Antagonizes Atg13 Phosphorylation and Promotes Autophagy after the Inactivation of TORC1 |
Q26795727 | Organelle-Specific Initiation of Autophagy |
Q58802893 | Overexpression of ULK1 Represents a Potential Diagnostic Marker for Clear Cell Renal Carcinoma and the Antitumor Effects of SBI-0206965 |
Q37765143 | Overview of macroautophagy regulation in mammalian cells |
Q36635744 | PAQR3 controls autophagy by integrating AMPK signaling to enhance ATG14L-associated PI3K activity |
Q42150529 | PEBP1, a RAF kinase inhibitory protein, negatively regulates starvation-induced autophagy by direct interaction with LC3. |
Q36594146 | PGC-1α promotes exercise-induced autophagy in mouse skeletal muscle |
Q38206682 | PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance |
Q52310328 | PP242 Counteracts Glioblastoma Cell Proliferation, Migration, Invasiveness and Stemness Properties by Inhibiting mTORC2/AKT. |
Q47070299 | PP2A regulates autophagy in two alternative ways in Drosophila |
Q52316229 | Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy. |
Q60955118 | Perspectives of RAS and RHEB GTPase Signaling Pathways in Regenerating Brain Neurons |
Q92809097 | Pexophagy: A Model for Selective Autophagy |
Q35242546 | Pharmacologic agents targeting autophagy |
Q30646716 | Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy |
Q36111810 | Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner |
Q38890133 | Phosphoinositide-binding proteins in autophagy |
Q34268347 | Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer |
Q33878926 | Phosphorylation of NBR1 by GSK3 modulates protein aggregation. |
Q29615616 | Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy |
Q48215511 | Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency |
Q28508500 | Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy |
Q57054936 | Plasma cells: the programming of an antibody-secreting machine |
Q38223047 | Pleiotropic roles of mTOR complexes in haemato-lymphopoiesis and leukemogenesis |
Q33645471 | Podocyte Autophagy: A Potential Therapeutic Target to Prevent the Progression of Diabetic Nephropathy |
Q99414253 | Polyphenol-Mediated Autophagy in Cancer: Evidence of In Vitro and In Vivo Studies |
Q38851817 | Polyunsaturated Branched-Chain Fatty Acid Geranylgeranoic Acid Induces Unfolded Protein Response in Human Hepatoma Cells |
Q90463782 | Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation |
Q35852919 | Posttranslational modification of autophagy-related proteins in macroautophagy |
Q61450099 | Potential ceRNA networks involved in autophagy suppression of pancreatic cancer caused by chloroquine diphosphate: A study based on differentially‑expressed circRNAs, lncRNAs, miRNAs and mRNAs |
Q28731609 | Preparation of mouse monoclonal antibody for RB1CC1 and its clinical application |
Q54577937 | Prognostic significance of RB1-inducible coiled-coil 1 in salivary gland cancers. |
Q37293151 | Prognostic value of autophagy related proteins ULK1, Beclin 1, ATG3, ATG5, ATG7, ATG9, ATG10, ATG12, LC3B and p62/SQSTM1 in gastric cancer |
Q34303405 | Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis |
Q38034272 | Programmed necrosis and autophagy in immune function |
Q41683471 | Progression of thanatophagy in cadaver brain and heart tissues |
Q35064974 | Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease |
Q97883064 | Protective Effects of Rapamycin on Trabecular Meshwork Cells in Glucocorticoid-Induced Glaucoma Mice |
Q91896679 | Protective Role of mTOR in Liver Ischemia/Reperfusion Injury: Involvement of Inflammation and Autophagy |
Q39043361 | Protective effect of autophagy inhibition on ischemia-reperfusion-induced injury of N2a cells |
Q57036995 | Protein Quality Control in the Endoplasmic Reticulum and Cancer |
Q100532878 | Protein metabolism and related body function - mechanistic approaches and health consequences |
Q91304470 | Protein: what's on in research on clinical nutrition |
Q28543694 | Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates |
Q33627736 | RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer |
Q35626134 | RB1CC1 protein suppresses type II collagen synthesis in chondrocytes and causes dwarfism |
Q33784718 | RB1CC1 together with RB1 and p53 predicts long-term survival in Japanese breast cancer patients |
Q58712490 | RB1CC1-enhanced autophagy facilitates PSCs activation and pancreatic fibrogenesis in chronic pancreatitis |
Q36939659 | RES-529: a PI3K/AKT/mTOR pathway inhibitor that dissociates the mTORC1 and mTORC2 complexes |
Q34662354 | ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells. |
Q33583930 | ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid |
Q40326577 | Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. |
Q38897874 | Rabin8 suppresses autophagosome formation independently of its guanine nucleotide-exchange activity towards Rab8. |
Q99350187 | Rac1 conditional deletion attenuates retinal ganglion cell apoptosis by accelerating autophagic flux in a mouse model of chronic ocular hypertension |
Q36618911 | Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes |
Q24337344 | RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly |
Q57182557 | Rapamycin and FK506 derivative TH2849 could ameliorate neurodegenerative diseases through autophagy with low immunosuppressive effect |
Q34718418 | Rapamycin upregulates autophagy by inhibiting the mTOR-ULK1 pathway, resulting in reduced podocyte injury |
Q41325784 | Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1. |
Q38022568 | Reactive oxygen species and autophagy in plants and algae |
Q92932473 | Recent progress in the role of autophagy in neurological diseases |
Q35985531 | Reconstitution of leucine-mediated autophagy via the mTORC1-Barkor pathway in vitro |
Q92223680 | Recruitment and Activation of the ULK1/Atg1 Kinase Complex in Selective Autophagy |
Q100332692 | Regulation and Function of Autophagy During Ferroptosis |
Q29547416 | Regulation mechanisms and signaling pathways of autophagy |
Q39420799 | Regulation of Autophagy through TORC1 and mTORC1. |
Q28608455 | Regulation of B Cell Differentiation by Intracellular Membrane-Associated Proteins and microRNAs: Role in the Antibody Response |
Q39802205 | Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. |
Q40685914 | Regulation of autophagic flux by CHIP. |
Q38224064 | Regulation of autophagy by amino acid availability in S. cerevisiae and mammalian cells |
Q36003000 | Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A. |
Q38161364 | Regulation of autophagy by kinases |
Q34995420 | Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers. |
Q27025162 | Regulation of cardiac autophagy by insulin-like growth factor 1 |
Q37765106 | Regulation of innate immune responses by autophagy-related proteins |
Q36662357 | Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2. |
Q29614493 | Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress |
Q27311465 | Regulators of autophagosome formation in Drosophila muscles |
Q35096637 | Relieving autophagy and 4EBP1 from rapamycin resistance |
Q38654396 | Remodeling of ER-exit sites initiates a membrane supply pathway for autophagosome biogenesis |
Q41169241 | Research Progress on Mechanism of Podocyte Depletion in Diabetic Nephropathy. |
Q97646299 | Research Progress on the Pathological Mechanisms of Podocytes in Diabetic Nephropathy |
Q58079140 | Resistance to endocrine therapy in breast cancer: molecular mechanisms and future goals |
Q37641525 | Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells |
Q24612235 | Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks |
Q30512687 | Role of ATG8 and autophagy in programmed nuclear degradation in Tetrahymena thermophila |
Q37919739 | Role of an intrinsically disordered conformation in AMPK-mediated phosphorylation of ULK1 and regulation of autophagy |
Q38144288 | Role of autophagy in cancer prevention, development and therapy |
Q35922012 | Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death |
Q26749232 | Role of autophagy in megakaryocyte differentiation and platelet formation |
Q64080622 | Role of autophagy in osteosarcoma |
Q41116590 | Role of mammalian target of rapamycin signaling in autophagy and the neurodegenerative process using a senescence accelerated mouse-prone 8 model |
Q37669247 | Roles for PI(3,5)P2 in nutrient sensing through TORC1. |
Q88515019 | Roles for neuronal and glial autophagy in synaptic pruning during development |
Q47745733 | Roles of Autophagy in Ischemic Heart Diseases and the Modulatory Effects of Chinese Herbal Medicine |
Q28077896 | Roles of N-Myc and STAT interactor in cancer: From initiation to dissemination |
Q38914374 | Roles of mTOR complexes in the kidney: implications for renal disease and transplantation. |
Q38917412 | Roles of mitophagy in cellular physiology and development |
Q110176308 | SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals |
Q24320106 | SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling |
Q33757027 | STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth |
Q46106014 | Salen-Mn compounds induces cell apoptosis in human prostate cancer cells through promoting AMPK activity and cell autophagy |
Q28476186 | Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling |
Q43208326 | Selective autophagy and Huntingtin: learning from disease |
Q38722026 | Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins |
Q37736687 | Sesamol Induces Human Hepatocellular Carcinoma Cells Apoptosis by Impairing Mitochondrial Function and Suppressing Autophagy |
Q33684305 | Sestrin 1 ameliorates cardiac hypertrophy via autophagy activation |
Q24300990 | Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1 |
Q64885927 | Shen-Yuan-Dan Capsule Attenuates Atherosclerosis and Foam Cell Formation by Enhancing Autophagy and Inhibiting the PI3K/Akt/mTORC1 Signaling Pathway. |
Q38111226 | Signal integration by mTORC1 coordinates nutrient input with biosynthetic output. |
Q90589491 | Signaling networks in immunometabolism |
Q34340780 | Signals from the lysosome: a control centre for cellular clearance and energy metabolism |
Q38982072 | Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells |
Q26749011 | Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects |
Q33944130 | Skeletal muscle homeostasis in duchenne muscular dystrophy: modulating autophagy as a promising therapeutic strategy |
Q34043851 | Skin healing and scale regeneration in fed and unfed sea bream, Sparus auratus. |
Q57465065 | So Many Roads: the Multifaceted Regulation of Autophagy Induction |
Q24612853 | Spatial regulation of the mTORC1 system in amino acids sensing pathway |
Q28084945 | Sphingolipids as cell fate regulators in lung development and disease |
Q41784281 | Src Family Kinase Inhibitor PP2 Induces LC3 Conversion in a Manner That is Uncoupled from Autophagy and Increases Apoptosis in Multidrug-Resistant Cells |
Q58425656 | Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy |
Q90065524 | Starvation-induced autophagy via calcium-dependent TFEB dephosphorylation is suppressed by Shigyakusan |
Q36023733 | Staying alive: metabolic adaptations to quiescence |
Q35206722 | Stearoyl-CoA desaturase 1 activity is required for autophagosome formation |
Q37041854 | Strategies Used by Bacteria to Grow in Macrophages |
Q38050926 | Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress |
Q37780207 | Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling |
Q37794096 | Stressin' Sestrins take an aging fight |
Q92013467 | Structural Biology and Electron Microscopy of the Autophagy Molecular Machinery |
Q36788728 | Structure and function of the ULK1 complex in autophagy |
Q27700943 | Structure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiation |
Q30378254 | Structure of the Human Atg13-Atg101 HORMA Heterodimer: an Interaction Hub within the ULK1 Complex. |
Q39389338 | Suppressed translation and ULK1 degradation as potential mechanisms of autophagy limitation under prolonged starvation |
Q38498596 | Suppression of autophagy by FIP200 deletion impairs DNA damage repair and increases cell death upon treatments with anticancer agents |
Q35128818 | Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis |
Q34697502 | Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. |
Q60049861 | Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK/ERK kinases |
Q47367395 | Systematic analysis of ATG13 domain requirements for autophagy induction. |
Q52671436 | Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response. |
Q45256565 | TFEB and TFE3: The art of multi-tasking under stress conditions |
Q33649816 | TOR is a negative regulator of autophagy in Arabidopsis thaliana |
Q33787702 | TOR-dependent control of autophagy: biting the hand that feeds |
Q39411030 | TORC1-Dependent Phosphorylation Targets in Fission Yeast |
Q33784625 | TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway |
Q47100954 | Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway |
Q35138543 | Targeting Rb inactivation in cancers by synthetic lethality. |
Q59353835 | Targeting autophagy in liver cancer |
Q91480154 | Targeting autophagy using natural compounds for cancer prevention and therapy |
Q38607849 | Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders |
Q37610497 | Targeting tissue-specific metabolic signaling pathways in aging: the promise and limitations |
Q35812423 | Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy |
Q46508073 | The ATG1/ATG13 protein kinase complex is both a regulator and a target of autophagic recycling in Arabidopsis |
Q41619017 | The Activation and Function of Autophagy in Alcoholic Liver Disease |
Q40121425 | The Atg1-kinase complex tethers Atg9-vesicles to initiate autophagy |
Q38698993 | The Atg17-Atg31-Atg29 Complex Coordinates with Atg11 to Recruit the Vam7 SNARE and Mediate Autophagosome-Vacuole Fusion |
Q44464070 | The C. elegans ATG101 homolog EPG-9 directly interacts with EPG-1/Atg13 and is essential for autophagy |
Q30235555 | The Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond |
Q84315437 | The ER stress sensor IRE1 and MAP kinase ERK modulate autophagy induction in cells infected with coronavirus infectious bronchitis virus |
Q89496691 | The Emerging Role of Sestrin2 in Cell Metabolism, and Cardiovascular and Age-Related Diseases |
Q35808638 | The Emerging Roles of Viroporins in ER Stress Response and Autophagy Induction during Virus Infection |
Q90283881 | The Emerging Roles of mTORC1 in Macromanaging Autophagy |
Q26777018 | The Function of Autophagy in Neurodegenerative Diseases |
Q90704578 | The Impairments of α-Synuclein and Mechanistic Target of Rapamycin in Rotenone-Induced SH-SY5Y Cells and Mice Model of Parkinson's Disease |
Q27718642 | The Intrinsically Disordered Protein Atg13 Mediates Supramolecular Assembly of Autophagy Initiation Complexes |
Q30502008 | The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella |
Q91692839 | The Lysosome Signaling Platform: Adapting With the Times |
Q26742170 | The Mucosal Immune System and Its Regulation by Autophagy |
Q37194679 | The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis |
Q28117863 | The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity |
Q64930743 | The Role of Autophagy in Liver Epithelial Cells and Its Impact on Systemic Homeostasis. |
Q39223884 | The Role of Autophagy in Subarachnoid Hemorrhage: An Update. |
Q64092333 | The Role of Primary Cilia in the Crosstalk between the Ubiquitin⁻Proteasome System and Autophagy |
Q38714678 | The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth |
Q42002950 | The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation |
Q37386075 | The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy |
Q38780596 | The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. |
Q38072216 | The ULK1 complex: sensing nutrient signals for autophagy activation. |
Q91962615 | The Upstream Pathway of mTOR-Mediated Autophagy in Liver Diseases |
Q33745164 | The association of AMPK with ULK1 regulates autophagy |
Q52687668 | The autophagic network and cancer. |
Q98286415 | The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment |
Q37888463 | The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming |
Q47663963 | The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway |
Q26749374 | The autophagy-lysosomal system in subarachnoid haemorrhage |
Q41851030 | The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole |
Q26865666 | The beginning of the end: how scaffolds nucleate autophagosome biogenesis |
Q57021022 | The cargo receptor SQSTM1 ameliorates neurofibrillary tangle pathology and spreading through selective targeting of pathological MAPT (microtubule associated protein tau) |
Q92952207 | The circadian rhythm in intervertebral disc degeneration: an autophagy connection |
Q35298106 | The complex interplay between autophagy and NF-κB signaling pathways in cancer cells |
Q34252212 | The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis |
Q52682539 | The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation. |
Q34191643 | The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy |
Q37781878 | The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration |
Q33894424 | The emerging role of autophagy in alcoholic liver disease. |
Q38166578 | The emerging role of the phosphatidylinositol 3-kinase/ akt/mammalian target of rapamycin signaling network in cancer stem cell biology |
Q90482001 | The functions and properties of cullin-5, a potential therapeutic target for cancers |
Q35146049 | The identification and analysis of phosphorylation sites on the Atg1 protein kinase. |
Q38196807 | The impact of autophagy on cell death modalities. |
Q37993106 | The incredible ULKs |
Q89395265 | The independence of and associations among apoptosis, autophagy, and necrosis |
Q38062538 | The interplay between autophagy and ROS in tumorigenesis |
Q90345270 | The interplay of autophagy and enterovirus |
Q33727929 | The intestinal TORC2 signaling pathway contributes to associative learning in Caenorhabditis elegans |
Q38122224 | The kinase triad, AMPK, mTORC1 and ULK1, maintains energy and nutrient homoeostasis |
Q37831801 | The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling |
Q33928657 | The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. |
Q38173673 | The machinery of macroautophagy |
Q47301180 | The mammalian ULK1 complex and autophagy initiation. |
Q38254507 | The molecular mechanisms between autophagy and apoptosis: potential role in central nervous system disorders. |
Q37840892 | The multiple roles of autophagy in cancer |
Q36418450 | The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris |
Q38559901 | The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control |
Q38889413 | The pathophysiology of defective proteostasis in the hypothalamus - from obesity to ageing |
Q33720239 | The pleiotropic roles of sphingolipid signaling in autophagy |
Q39957350 | The putative HORMA domain protein Atg101 dimerizes and is required for starvation-induced and selective autophagy in Drosophila. |
Q36698649 | The regulation of autophagy during exercise in skeletal muscle |
Q38740000 | The renewed battle against RAS-mutant cancers |
Q35146045 | The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy |
Q41339988 | The role of autophagy in hepatocellular carcinoma: friend or foe. |
Q90295253 | The role of autophagy in intestinal epithelial injury |
Q26851073 | The role of autophagy in the pathogenesis of diabetic nephropathy |
Q34317238 | The role of autophagy in the placenta as a regulator of cell death |
Q37954130 | The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β-cell mass: implications in the development of type-2 diabetes. |
Q38655147 | The role of mechanistic target of rapamycin in maintenance of glomerular epithelial cells |
Q38199772 | The role of mitochondria in mTOR-regulated longevity |
Q41470238 | The role of the selective adaptor p62 and ubiquitin-like proteins in autophagy. |
Q34347017 | The role of ubiquitin in autophagy-dependent protein aggregate processing |
Q50335546 | The serine/threonine kinase ULK1 is a target of multiple phosphorylation events. |
Q34535073 | The ubiquitin-proteasome system and autophagy: Coordinated and independent activities |
Q40051484 | Therapeutic Implications of Autophagy Inducers in Immunological Disorders, Infection, and Cancer |
Q38176862 | Therapeutic potential and adverse events of everolimus for treatment of hepatocellular carcinoma - systematic review and meta-analysis |
Q38648562 | Therapeutic potential of mTOR inhibitors for targeting cancer stem cells |
Q37236107 | Therapeutic targeting of autophagy in disease: biology and pharmacology |
Q27021382 | Therapeutic targeting of autophagy in neurodegenerative and infectious diseases |
Q26830282 | Therapeutic targeting of autophagy: potential and concerns in treating cardiovascular disease |
Q49886970 | To be or not to be cell autonomous? Autophagy says both |
Q38809310 | To eat, or NOt to eat: S-nitrosylation signaling in autophagy. |
Q33627273 | Tor directly controls the Atg1 kinase complex to regulate autophagy |
Q38344277 | Transcription factors and cognate signalling cascades in the regulation of autophagy |
Q91942557 | Transcriptional Regulation of Autophagy: Mechanisms and Diseases |
Q37572139 | Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy |
Q36034647 | Transcriptional control of circadian metabolic rhythms in the liver |
Q38953220 | Transient overexpression of Werner protein rescues starvation induced autophagy in Werner syndrome cells |
Q47103021 | Transiently expressed ATG16L1 inhibits autophagosome biogenesis and aberrantly targets RAB11-positive recycling endosomes |
Q47108526 | Triptolide Restores Autophagy to Alleviate Diabetic Renal Fibrosis through the miR-141-3p/PTEN/Akt/mTOR Pathway |
Q24632884 | Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly |
Q36049513 | Tuberous sclerosis complex 2 loss increases lysophosphatidylcholine synthesis in lymphangioleiomyomatosis. |
Q42136875 | Tumor suppression and promotion by autophagy |
Q34199557 | Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent |
Q42366609 | Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1. |
Q24649645 | ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery |
Q96950740 | ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins |
Q34728044 | ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. |
Q41953170 | ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding |
Q38976176 | ULK1 inhibits the kinase activity of mTORC1 and cell proliferation |
Q50286492 | ULK1 phosphorylates ATG13 and RB1CC1 |
Q91769899 | ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint |
Q36367255 | ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-to-Golgi traffic. |
Q47219778 | ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction. |
Q34805831 | ULK1, mammalian target of rapamycin, and mitochondria: linking nutrient availability and autophagy |
Q38261262 | UNC51-like kinase 1, autophagic regulator and cancer therapeutic target |
Q36650365 | Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling |
Q35667361 | Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathy |
Q47442783 | Uncoordinated 51-like kinase 2 signaling pathway regulates epithelial-mesenchymal transition in A549 lung cancer cells |
Q92613379 | Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to targeted cancer therapy |
Q26382049 | Unified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapy |
Q38810023 | Unraveling the actions of AMP-activated protein kinase in metabolic diseases: Systemic to molecular insights |
Q38198765 | Unravelling the multifaceted roles of Atg proteins to improve cancer therapy |
Q40994687 | Upregulation of autophagy components in alcoholic hepatitis and nonalcoholic steatohepatitis |
Q35210639 | Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death |
Q37448146 | Vesicular trafficking and autophagosome formation |
Q27491341 | Viruses and autophagy |
Q37501726 | Voluntary resistance wheel exercise from mid-life prevents sarcopenia and increases markers of mitochondrial function and autophagy in muscles of old male and female C57BL/6J mice. |
Q30854841 | WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy |
Q35965763 | WISP1 (CCN4) autoregulates its expression and nuclear trafficking of β-catenin during oxidant stress with limited effects upon neuronal autophagy |
Q41853953 | When autophagy meets cancer through p62/SQSTM1. |
Q37791919 | When autophagy meets viruses: a double-edged sword with functions in defense and offense |
Q28305068 | Where is mTOR and what is it doing there? |
Q41312189 | Withdrawal of essential amino acids increases autophagy by a pathway involving Ca2+/calmodulin-dependent kinase kinase-β (CaMKK-β) |
Q46621260 | Ypt1 and COPII vesicles act in autophagosome biogenesis and the early secretory pathway |
Q37831557 | Zebrafish as a model to understand autophagy and its role in neurological disease |
Q54577849 | [« Self-eating » to survive - coordinated regulation of autophagy by nutrients]. |
Q48530866 | mTOR Cross-Talk in Cancer and Potential for Combination Therapy. |
Q37771869 | mTOR Mediated Anti-Cancer Drug Discovery |
Q49259139 | mTOR Pathways in Cancer and Autophagy |
Q33962054 | mTOR Signaling from Cellular Senescence to Organismal Aging |
Q64274877 | mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy |
Q27007511 | mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic Interventions |
Q40771740 | mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival |
Q33942076 | mTOR and lysosome regulation |
Q90854370 | mTOR as a central hub of nutrient signalling and cell growth |
Q92643974 | mTOR at the nexus of nutrition, growth, ageing and disease |
Q38199194 | mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse |
Q36189549 | mTOR coordinates protein synthesis, mitochondrial activity and proliferation |
Q37667610 | mTOR enhances foam cell formation by suppressing the autophagy pathway |
Q41792378 | mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. |
Q38814395 | mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells |
Q29616301 | mTOR regulation of autophagy |
Q29619857 | mTOR signaling at a glance |
Q38229078 | mTOR signaling in T cell immunity and autoimmunity |
Q38184060 | mTOR signaling in autophagy regulation in the kidney |
Q24634174 | mTOR signaling in growth control and disease |
Q38057633 | mTOR signaling in neural stem cells: from basic biology to disease |
Q37693034 | mTOR's role in ageing: protein synthesis or autophagy? |
Q42790841 | mTOR, AMBRA1, and autophagy: an intricate relationship |
Q60800989 | mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders |
Q24294367 | mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis |
Q26864688 | mTOR-dependent cell survival mechanisms |
Q28078490 | mTOR: An attractive therapeutic target for osteosarcoma? |
Q38345168 | mTOR: a pharmacologic target for autophagy regulation |
Q28087019 | mTOR: a potential therapeutic target in osteoarthritis? |
Q24633662 | mTOR: from growth signal integration to cancer, diabetes and ageing |
Q52357229 | mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome. |
Q36005418 | mTORC1 is essential for leukemia propagation but not stem cell self-renewal |
Q35007765 | mTORC1 phosphorylates UVRAG to negatively regulate autophagosome and endosome maturation |
Q37166913 | mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin |
Q27012468 | mTORC1 signaling activates NRF1 to increase cellular proteasome levels |
Q39243905 | mTORC1 signaling and the metabolic control of cell growth |
Q39256910 | mTORC1 signaling in hepatic lipid metabolism |
Q37817590 | mTORC1 signaling: what we still don't know |
Q37929699 | mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused. |
Q55413938 | miR-519a enhances chemosensitivity and promotes autophagy in glioblastoma by targeting STAT3/Bcl2 signaling pathway. |
Q98513731 | p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy-lysosomal pathway and coordinate cell cycle and cell growth |
Q47292147 | p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1. |
Q28508630 | p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding |
Q33738032 | p62/SQSTM1 synergizes with autophagy for tumor growth in vivo |
Q36022303 | α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway. |
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