scholarly article | Q13442814 |
P50 | author | Augustine M K Choi | Q114342087 |
P2093 | author name string | Jeffrey A Haspel | |
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HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates | Q24296107 | ||
Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L) | Q24300421 | ||
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy | Q24310301 | ||
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy | Q24312147 | ||
Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation | Q24315722 | ||
A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation | Q24315723 | ||
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | Q24597817 | ||
Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria | Q24631535 | ||
The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis | Q24646191 | ||
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy | Q24647053 | ||
Organization of the pre-autophagosomal structure responsible for autophagosome formation | Q24647076 | ||
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery | Q24649645 | ||
Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function | Q24655432 | ||
Autophagy in the Pathogenesis of Disease | Q27860558 | ||
Hierarchy of Atg proteins in pre-autophagosomal structure organization | Q27931408 | ||
In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy | Q27935810 | ||
A role for mitochondria in NLRP3 inflammasome activation | Q28131794 | ||
A molecular chaperone complex at the lysosomal membrane is required for protein translocation | Q28216426 | ||
LC3 conjugation system in mammalian autophagy | Q28278334 | ||
The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond | Q28278349 | ||
LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis | Q28280603 | ||
Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking | Q28289648 | ||
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease | Q28304318 | ||
Animal models of chronic obstructive pulmonary disease | Q28385105 | ||
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy | Q35749637 | ||
Glycogen autophagy in glucose homeostasis | Q36510005 | ||
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes | Q37014368 | ||
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease | Q37089630 | ||
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling | Q37115242 | ||
Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa | Q37375775 | ||
Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages. | Q37463450 | ||
Autophagy in tumour suppression and promotion | Q37533134 | ||
Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding | Q37608783 | ||
Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration | Q37774072 | ||
Autophagy and misfolded proteins in neurodegeneration | Q37811463 | ||
Ubiquitination-mediated autophagy against invading bacteria | Q37859498 | ||
Combinational soluble N-ethylmaleimide-sensitive factor attachment protein receptor proteins VAMP8 and Vti1b mediate fusion of antimicrobial and canonical autophagosomes with lysosomes | Q39570095 | ||
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition | Q39667316 | ||
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis. | Q39696852 | ||
Investigating autophagy: quantitative morphometric analysis using electron microscopy | Q39713961 | ||
Cigarette smoke synergizes lipopolysaccharide-induced interleukin-1β and tumor necrosis factor-α secretion from macrophages via substance P-mediated nuclear factor-κB activation | Q39738730 | ||
SUMOylation of tissue transglutaminase as link between oxidative stress and inflammation. | Q39821994 | ||
Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. | Q39837169 | ||
Streptococcus-, Shigella-, and Listeria-induced autophagy | Q39886241 | ||
The GST-BHMT assay and related assays for autophagy. | Q39886278 | ||
Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. | Q39943586 | ||
Tissue transglutaminase activation modulates inflammation in cystic fibrosis via PPARgamma down-regulation. | Q39980536 | ||
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth | Q40105523 | ||
The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function | Q40250486 | ||
The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes | Q40250494 | ||
Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli | Q40303456 | ||
Oxygen consumption of human peripheral blood mononuclear cells in severe human sepsis | Q44238409 | ||
Differential gene expression analysis in human monocyte-derived macrophages: impact of cigarette smoke on host defence | Q44423945 | ||
An electron microscopic and biochemical study of the effects of glucagon on glycogen autophagy in the liver and heart of newborn rats | Q44727676 | ||
Microautophagy of cytosolic proteins by late endosomes | Q28509224 | ||
Unique properties of lamp2a compared to other lamp2 isoforms | Q28569157 | ||
Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo | Q28592180 | ||
Methods in mammalian autophagy research | Q29547276 | ||
Autophagy: process and function | Q29547296 | ||
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome | Q29547419 | ||
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages | Q29547420 | ||
Autophagy regulates lipid metabolism | Q29547421 | ||
Autophagy as a regulated pathway of cellular degradation | Q29547914 | ||
How to interpret LC3 immunoblotting | Q29614175 | ||
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production | Q29614472 | ||
Human IRGM induces autophagy to eliminate intracellular mycobacteria | Q29614486 | ||
Mitochondria supply membranes for autophagosome biogenesis during starvation | Q29614495 | ||
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum | Q29614500 | ||
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy | Q29622819 | ||
How do cystic fibrosis transmembrane conductance regulator mutations produce lung disease? | Q30428820 | ||
An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure | Q30484302 | ||
ER-associated complexes (ERACs) containing aggregated cystic fibrosis transmembrane conductance regulator (CFTR) are degraded by autophagy. | Q30488209 | ||
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins | Q30512856 | ||
Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes | Q31154479 | ||
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease | Q33373335 | ||
Electron tomography reveals the endoplasmic reticulum as a membrane source for autophagosome formation | Q33526771 | ||
Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy | Q33588721 | ||
Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans | Q33809035 | ||
Seeing is believing: the impact of electron microscopy on autophagy research | Q33897723 | ||
Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD. | Q33996365 | ||
Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L. | Q34083183 | ||
Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis | Q34120776 | ||
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47 | Q34272123 | ||
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema | Q34279364 | ||
Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters. | Q34355428 | ||
Organelle membrane proteomics reveals differential influence of mycobacterial lipoglycans on macrophage phagosome maturation and autophagosome accumulation | Q34477748 | ||
Suppression of autophagy permits successful enzyme replacement therapy in a lysosomal storage disorder--murine Pompe disease | Q34577206 | ||
Discovery of Atg5/Atg7-independent alternative macroautophagy | Q34612369 | ||
Identification of an autophagy defect in smokers' alveolar macrophages. | Q34671233 | ||
Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation | Q34684708 | ||
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels | Q35146053 | ||
Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3. | Q35189872 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | autophagy | Q288322 |
P1104 | number of pages | 10 | |
P304 | page(s) | 1237-1246 | |
P577 | publication date | 2011-08-11 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | American Journal of Respiratory and Critical Care Medicine | Q4744267 |
P1476 | title | Autophagy: a core cellular process with emerging links to pulmonary disease | |
P478 | volume | 184 |
Q45970202 | Autophagy and the Unfolded Protein Response Promote Pro-fibrotic Effects of TGFβ1 in Human Lung Fibroblasts. |
Q29247883 | Autophagy as a Possible Underlying Mechanism of Nanomaterial Toxicity |
Q38942187 | Autophagy in Pulmonary Diseases |
Q54166672 | Berberine inhibits Smad and non-Smad signaling cascades and enhances autophagy against pulmonary fibrosis |
Q37133567 | CFTR activity and mitochondrial function |
Q36876624 | Cartography of Pathway Signal Perturbations Identifies Distinct Molecular Pathomechanisms in Malignant and Chronic Lung Diseases. |
Q39241395 | Cigarette smoking affects oxidative protein folding in endoplasmic reticulum by modifying protein disulfide isomerase |
Q38454300 | Construction of a computable network model for DNA damage, autophagy, cell death, and senescence |
Q39023157 | Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia. |
Q37607834 | Discovery of Emphysema Relevant Molecular Networks from an A/J Mouse Inhalation Study Using Reverse Engineering and Forward Simulation (REFS™). |
Q45287617 | Epigenetic mechanisms through which Toll-like receptor-9 drives idiopathic pulmonary fibrosis progression. |
Q30452653 | Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis |
Q51664427 | Fluorescent-based evaluation of chaperone-mediated autophagy and microautophagy activities in cultured cells. |
Q51297017 | Gender differences in the bronchoalveolar lavage cell proteome of patients with chronic obstructive pulmonary disease |
Q51069008 | Impairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-κB pathway |
Q53812258 | Implication of autophagy in lung diseases and response to nanoparticles |
Q36880440 | Lack of autophagy induces steroid-resistant airway inflammation. |
Q64237303 | Ligustrazin increases lung cell autophagy and ameliorates paraquat-induced pulmonary fibrosis by inhibiting PI3K/Akt/mTOR and hedgehog signalling via increasing miR-193a expression |
Q37364177 | Macrophage-derived MCPIP1 mediates silica-induced pulmonary fibrosis via autophagy |
Q36688480 | Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis |
Q39567618 | New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis |
Q64904496 | Nur77 promotes cigarette smoke‑induced autophagic cell death by increasing the dissociation of Bcl2 from Beclin-1. |
Q26861392 | Oxidative stress-induced autophagy: role in pulmonary toxicity |
Q64246014 | Protective Features of Autophagy in Pulmonary Infection and Inflammatory Diseases |
Q42510251 | Role of OSGIN1 in mediating smoking-induced autophagy in the human airway epithelium. |
Q38108325 | Self-eating: friend or foe? The emerging role of autophagy in idiopathic pulmonary fibrosis |
Q35585078 | Streptococcus pneumoniae induces autophagy through the inhibition of the PI3K-I/Akt/mTOR pathway and ROS hypergeneration in A549 cells |
Q36741049 | Structure, functional regulation and signaling properties of Rap2B. |
Q27316930 | V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis |
Q35780096 | mTOR Overactivation and Compromised Autophagy in the Pathogenesis of Pulmonary Fibrosis. |
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