Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia.

scientific article published on 19 February 2014

Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00109-014-1132-7
P698PubMed publication ID24535031
P5875ResearchGate publication ID260241606

P50author???Q64862675
Inés López-AlonsoQ50277985
Guillermo M AlbaicetaQ50277993
Álvaro F. FernándezQ51069057
Adrian Gonzalez-LopezQ64684179
Aurora Astudillo-GonzálezQ64854980
Laura Amado-RodríguezQ82642624
P2093author name stringAlina Aguirre
Estefanía Batalla-Solís
Claudia C dos Santos
Jorge Blázquez-Prieto
P2860cites workGuidelines for the use and interpretation of assays for monitoring autophagyQ21996341
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient miceQ24303752
Autophagy in immunity and inflammationQ24595707
The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathwayQ24630760
Autophagy is essential for mouse sense of balanceQ28591463
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasomeQ29547419
Eaten alive: a history of macroautophagyQ29617841
Rapamycin protects mice from staphylococcal enterotoxin B-induced toxic shock and blocks cytokine release in vitro and in vivoQ33676236
MMP-8 Deficiency Increases TLR/RAGE Ligands S100A8 and S100A9 and Exacerbates Lung Inflammation during EndotoxemiaQ34328435
Autophagy: a core cellular process with emerging links to pulmonary diseaseQ35683041
Autophagy: molecular mechanisms, physiological functions and relevance in human pathologyQ35805446
Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammationQ36916340
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitisQ37107133
Cellular dysfunction in sepsisQ37309578
Fighting disease by selective autophagy of aggregate-prone proteinsQ37735987
Multiple organ failure in sepsis: prognosis and role of systemic inflammatory responseQ37846478
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.Q38313431
Activating transcription factor 3 confers protection against ventilator-induced lung injury.Q38344617
Autophagy is required for the activation of NFκB.Q39424847
Tissue transglutaminase activation modulates inflammation in cystic fibrosis via PPARgamma down-regulation.Q39980536
Negative regulation of TLR-signaling pathways by activating transcription factor-3.Q40085369
To aggregate or not to aggregate? A new role for p62.Q42131658
Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patientsQ42687663
Acute stress response in calorie-restricted rats to lipopolysaccharide-induced inflammationQ46423039
Lack of matrix metalloproteinase-9 worsens ventilator-induced lung injury.Q47958191
Mechanical ventilation-induced diaphragm disuse in humans triggers autophagyQ48123019
Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense ProgramQ50026118
Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndromeQ51023210
Impairment of autophagy decreases ventilator-induced lung injury by blockade of the NF-κB pathwayQ51069008
Refeeding with a standard diet after a 48-h fast elicits an inflammatory response in the mouse liverQ51346050
ATF3 regulates the stability of p53: a link to cancerQ53626549
An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animalsQ84005909
Inflammation and matrix remodeling during repair of ventilator-induced lung injuryQ84532143
P433issue6
P921main subjectautophagyQ288322
pulmonary injuryQ7259546
P304page(s)665-676
P577publication date2014-02-19
P1433published inJournal of Molecular MedicineQ6295593
P1476titleDefective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia
P478volume92

Reverse relations

cites work (P2860)
Q40077917ATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons
Q41698197Activation of MTOR in pulmonary epithelium promotes LPS-induced acute lung injury
Q89965820Autophagy Protects Against Developing Increased Lung Permeability and Hypoxemia by Down Regulating Inflammasome Activity and IL-1β in LPS Plus Mechanical Ventilation-Induced Acute Lung Injury
Q38687611Autophagy as a double-edged sword in pulmonary epithelial injury: a review and perspective
Q41556463Autophagy in sepsis: Degradation into exhaustion?
Q47942941Autophagy maintains the integrity of endothelial barrier in LPS-induced lung injury.
Q42152446Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation
Q49751937Autophagy: A Potential Therapeutic Target for Reversing Sepsis-Induced Immunosuppression
Q43089426Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1.
Q38893443Differential regulation of autophagy and mitophagy in pulmonary diseases
Q38779731Effects of Estrogen and Phytoestrogen Treatment on an In Vitro Model of Recurrent Stroke on HT22 Neuronal Cell Line.
Q100761744Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis
Q88410634Inhibition of autophagy with 3-methyladenine is protective in a lethal model of murine endotoxemia and polymicrobial sepsis
Q26801464Interactions between Autophagy and Bacterial Toxins: Targets for Therapy?
Q38826753Iron Loading Exaggerates the Inflammatory Response to the Toll-like Receptor 4 Ligand Lipopolysaccharide by Altering Mitochondrial Homeostasis.
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Q40734205The lung is protected from spontaneous inflammation by autophagy in myeloid cells

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