ATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons

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ATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-017-08584-9
P8608Fatcat IDrelease_tnkc25cmvnddrk3ce47w35lina
P932PMC publication ID5562757
P698PubMed publication ID28821775

P50authorManjula KaliaQ54435473
Vikas SoodQ114402603
P2093author name stringShantanu Chowdhury
Shigetaka Kitajima
Manish Sharma
Vishal Gupta
Parashar Dhapola
Kiran Bala Sharma
Sudhanshu Vrati
Dhurjhoti Saha
Utsav Sen
P2860cites workThe IKK complex contributes to the induction of autophagyQ24329117
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Activating transcription factor 3 protects against pressure-overload heart failure via the autophagy molecule Beclin-1 pathway.Q53065833
Coxsackievirus B3 modulates cell death by downregulating activating transcription factor 3 in HeLa cellsQ53544020
Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathwayQ81358751
Enhanced expression of aquaporin 9 in activated polymorphonuclear leukocytes in patients with systemic inflammatory response syndromeQ88183912
FoxO transcription factors promote autophagy in cardiomyocytesQ37459990
Cytoplasmic functions of the tumour suppressor p53.Q37466228
New function of type I IFN: induction of autophagyQ37585057
Autophagy regulation by p53.Q37665668
Type I interferons: crucial participants in disease amplification in autoimmunityQ37666513
The Guanylate-Binding Proteins: Emerging Insights into the Biochemical Properties and Functions of This Family of Large Interferon-Induced Guanosine TriphosphataseQ37818303
The JAK-STAT Pathway at TwentyQ38004201
ATF3 Is a Key Regulator of Macrophage IFN ResponsesQ38296292
PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3.Q38308555
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.Q38313431
Type I interferons in anticancer immunityQ38509280
Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia.Q39023157
Autophagy is required for the activation of NFκB.Q39424847
The induction of STAT1 gene by activating transcription factor 3 contributes to pancreatic beta-cell apoptosis and its dysfunction in streptozotocin-treated miceQ39684588
Activating transcription factor 3 is a positive regulator of human IFNG gene expressionQ39725244
E2F1 regulates autophagy and the transcription of autophagy genesQ39992419
Negative regulation of TLR-signaling pathways by activating transcription factor-3.Q40085369
Molecular characterization of an Indian isolate of Japanese encephalitis virus that shows an extended lag phase during growthQ40939349
A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammalsQ42020759
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagyQ42058524
Mammalian seryl-tRNA synthetase associates with mRNA in vivo and has homology to elongation factor 1 alphaQ42624368
Toll-like receptor signaling alters the expression of regulator of G protein signaling proteins in dendritic cells: implications for G protein-coupled receptor signalingQ47726142
Phosphoserine phosphatase is expressed in the neural stem cell niche and regulates neural stem and progenitor cell proliferationQ48171563
Dengue Virus Induces Novel Changes in Gene Expression of Human Umbilical Vein Endothelial CellsQ27485730
Interferon-inducible antiviral effectorsQ27486790
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA virusesQ27860455
Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeastQ27939948
Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiencyQ28249019
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptorsQ28260114
Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterolQ28282311
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress responseQ28508156
The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid MetabolismQ28512608
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathyQ30557070
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.Q33565025
ATF3 and stress responses.Q33706914
Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cellsQ33911282
Growth Differentiation Factor 15 Is Induced by Hepatitis C Virus Infection and Regulates Hepatocellular Carcinoma-Related GenesQ33916208
Regulation of T cell activation, anxiety, and male aggression by RGS2.Q33920958
STEME: efficient EM to find motifs in large data setsQ33969838
Systems analysis of ATF3 in stress response and cancer reveals opposing effects on pro-apoptotic genes in p53 pathway.Q34064732
Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranesQ34388800
Interferon-stimulated genes: a complex web of host defensesQ34405609
Neurons produce type I interferon during viral encephalitisQ34595308
The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.Q34712316
Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formationQ35115608
Cutting Edge: Regulator of G protein signaling-1 selectively regulates gut T cell trafficking and colitic potentialQ35195555
Inhibition of System Xc(-) Transporter Attenuates Autoimmune Inflammatory DemyelinationQ35815842
ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol–induced lipid body formationQ35894184
RIP3 Regulates Autophagy and Promotes Coxsackievirus B3 Infection of Intestinal Epithelial CellsQ36035406
Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in gangliaQ36120357
A Neuron-Specific Role for Autophagy in Antiviral Defense against Herpes Simplex VirusQ36266460
ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cellsQ36497388
A critical role of STAT1 in streptozotocin-induced diabetic liver injury in mice: controlled by ATF3.Q36655185
JAK-STAT signaling: from interferons to cytokinesQ36821751
Type I interferons induce autophagy in certain human cancer cell linesQ36892069
Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammationQ36916340
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
P304page(s)8789
P577publication date2017-08-18
P1433published inScientific ReportsQ2261792
P1476titleATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons
P478volume7

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cites work (P2860)
Q90010524Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15
Q98733271Dengue Virus Degrades USP33-ATF3 Axis via Extracellular Vesicles to Activate Human Microglial Cells
Q92257516Review of Emerging Japanese Encephalitis Virus: New Aspects and Concepts about Entry into the Brain and Inter-Cellular Spreading

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