scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Andrew Kinloch | Q81459128 |
P2093 | author name string | Patrick J Venables | |
Anne-Marie Quirke | |||
Benjamin A C Fisher | |||
P2860 | cites work | Histone deimination antagonizes arginine methylation | Q24302163 |
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4 | Q24538382 | ||
RANK is essential for osteoclast and lymph node development | Q24598872 | ||
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TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study | Q24657292 | ||
Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis | Q24801080 | ||
Identification of citrullinated alpha-enolase as a candidate autoantigen in rheumatoid arthritis | Q24813085 | ||
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis | Q28183279 | ||
PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease | Q28212615 | ||
A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population | Q28255873 | ||
Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6 | Q28256812 | ||
Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis | Q28264978 | ||
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis | Q28267921 | ||
Association between PADI4 and rheumatoid arthritis: a replication study | Q28275244 | ||
Human PAD4 regulates histone arginine methylation levels via demethylimination | Q28280359 | ||
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Protein carbamylation links inflammation, smoking, uremia and atherogenesis. | Q30364367 | ||
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis | Q33982255 | ||
Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies. | Q34015846 | ||
Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study. | Q34027609 | ||
The rheumatoid arthritis HLA-DRB1 shared epitope | Q34067135 | ||
PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population | Q34081898 | ||
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps | Q34096547 | ||
HLA class II association with rheumatoid arthritis: facts and interpretations | Q34132727 | ||
Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis | Q34137749 | ||
Twin concordance rates for rheumatoid arthritis: results from a nationwide study. | Q34357436 | ||
Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin. | Q34388910 | ||
PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population | Q46584884 | ||
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells | Q46643896 | ||
Induction of macrophage secretion of tumor necrosis factor alpha through Fcgamma receptor IIa engagement by rheumatoid arthritis-specific autoantibodies to citrullinated proteins complexed with fibrinogen | Q46724742 | ||
Specific citrullination causes assembly of a globular S100A3 homotetramer: a putative Ca2+ modulator matures human hair cuticle | Q46847500 | ||
Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation | Q46925018 | ||
Blood transfusion, smoking, and obesity as risk factors for the development of rheumatoid arthritis: results from a primary care-based incident case-control study in Norfolk, England. | Q50925165 | ||
Cigarette smoking increases the risk of rheumatoid arthritis. Results from a nationwide study of disease-discordant twins. | Q51032043 | ||
Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis. | Q52917057 | ||
A "case control" study on the rôle of HLA DR4 in severe periodontitis and rapidly progressive periodontitis. Identification of types and subtypes using molecular biology (PCR.SSO). | Q53348043 | ||
2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative | Q56506042 | ||
Rheumatoid arthritis | Q57349151 | ||
Cleavage and activation of proteinase-activated receptor-2 on human neutrophils by gingipain-R from Porphyromonas gingivalis | Q58023171 | ||
Antibodies to Porphyromonas gingivalis Are Associated with Anticitrullinated Protein Antibodies in Patients with Rheumatoid Arthritis and Their Relatives | Q58234823 | ||
Identification of citrullinated vimentin peptides as T cell epitopes in HLAâ DR4â positive patients with rheumatoid arthritis | Q58234841 | ||
Decreasing incidence and prevalence of rheumatoid arthritis in pima indians over a twenty-five—year period | Q59150875 | ||
Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis | Q34498921 | ||
Citrullination: a posttranslational modification in health and disease | Q34531257 | ||
Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal women: results from the Iowa Women's Health Study | Q34604666 | ||
Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis | Q35011877 | ||
Immune dysregulation by the rheumatoid arthritis shared epitope | Q35037009 | ||
A family based study shows no association between rheumatoid arthritis and the PADI4 gene in a white French population | Q35555382 | ||
The association between periodontal disease and joint destruction in rheumatoid arthritis extends the link between the HLA-DR shared epitope and severity of bone destruction | Q35637373 | ||
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis | Q35752661 | ||
Erosive arthritis | Q35901078 | ||
Serum vascular markers and vascular imaging in assessment of rheumatoid arthritis disease activity and response to therapy. | Q36006214 | ||
Rheumatoid arthritis in American Indians and Alaska Natives: a review of the literature | Q36031009 | ||
Use and significance of anti-CCP autoantibodies in rheumatoid arthritis | Q36270234 | ||
Hypothesis: the humoral immune response to oral bacteria provides a stimulus for the development of rheumatoid arthritis | Q36294995 | ||
Monocytes regulate osteoclast-activating factor production by releasing prostaglandins | Q36342717 | ||
Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice | Q36537972 | ||
Citrullinated proteins in rheumatoid arthritis: crucial...but not sufficient! | Q36639940 | ||
Cigarette smoking and autoimmune disease: what can we learn from epidemiology? | Q36677000 | ||
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis | Q36955312 | ||
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. | Q37124853 | ||
Rheumatoid arthritis and smoking: putting the pieces together | Q37350863 | ||
Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis | Q37700775 | ||
Epitope spreading of the anti-citrullinated protein antibody response occurs before disease onset and is associated with the disease course of early arthritis | Q39875697 | ||
Pathogenic strategies of the oral anaerobe, Porphyromonas gingivalis | Q40512781 | ||
Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite | Q40917292 | ||
Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll‐like receptor 4 and Fcγ receptor | Q41612590 | ||
Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins | Q41825751 | ||
Expression and activity of citrullinating peptidylarginine deiminase enzymes in monocytes and macrophages | Q41855355 | ||
Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice. | Q41870758 | ||
Citrullination is an inflammation-dependent process | Q42140650 | ||
A novel superfamily of enzymes that catalyze the modification of guanidino groups. | Q42656917 | ||
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination | Q42676934 | ||
Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis | Q42874449 | ||
Anticitrulline antibodies can be caused by homocitrulline-containing proteins in rabbits. | Q42975230 | ||
Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis | Q44064388 | ||
Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis | Q44616885 | ||
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins | Q44687984 | ||
Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study | Q44800314 | ||
The presence of citrullinated proteins is not specific for rheumatoid synovial tissue | Q45141270 | ||
Determination of cyanide exposure by gas chromatography-mass spectrometry analysis of cyanide-exposed plasma proteins. | Q45589696 | ||
An intriguing relationship between the immune response to citrullinated vimentin and the HLA shared epitope: comment on the article by Verpoort et al. | Q46343359 | ||
Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase. | Q46343375 | ||
Humoral immune response to citrullinated collagen type II determinants in early rheumatoid arthritis | Q46439121 | ||
Synovial fluid is a site of citrullination of autoantigens in inflammatory arthritis | Q46453983 | ||
P433 | issue | 23 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | rheumatoid arthritis | Q187255 |
pathogenesis | Q372016 | ||
P304 | page(s) | 3681-3688 | |
P577 | publication date | 2011-06-23 | |
P1433 | published in | FEBS Letters | Q1388051 |
P1476 | title | Citrullination of autoantigens: upstream of TNFα in the pathogenesis of rheumatoid arthritis | |
P478 | volume | 585 |
Q53132137 | Anti-citrullinated protein antibodies activated ERK1/2 and JNK mitogen-activated protein kinases via binding to surface-expressed citrullinated GRP78 on mononuclear cells. |
Q52932746 | Comparative analysis of autoantibodies targeting peptidylarginine deiminase type 4, mutated citrullinated vimentin and cyclic citrullinated peptides in rheumatoid arthritis: associations with cytokine profiles, clinical and genetic features. |
Q28085328 | Control of cytokine production by human fc gamma receptors: implications for pathogen defense and autoimmunity |
Q40401924 | Epidemiology: Then and Now. |
Q34568233 | Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages |
Q35946934 | Gilt required for RTL550-CYS-MOG to treat experimental autoimmune encephalomyelitis |
Q37465513 | Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis. |
Q40834260 | How citrullination invaded rheumatoid arthritis research |
Q38632859 | Incidence of inflammatory joint diseases in Finland: results from a population-based epidemiological study |
Q34105680 | Peptidylarginine deiminase 4 contributes to tumor necrosis factor α-induced inflammatory arthritis |
Q37690985 | Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease |
Q40081890 | The case for periodontitis in the pathogenesis of rheumatoid arthritis |
Q51679039 | The dependency on neighboring amino acids for reactivity of anti-citrullinated protein antibodies to citrullinated proteins. |
Q27022645 | The effect of targeted rheumatoid arthritis therapies on anti-citrullinated protein autoantibody levels and B cell responses |
Q36456814 | The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA. |
Q64945497 | The inflammatory function of human IgA. |
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