| scholarly article | Q13442814 |
| P2093 | author name string | Thorsten Wolff | |
| Bianca Dauber | |||
| P2860 | cites work | Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon | Q24301655 |
| Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus | Q24310706 | ||
| Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus | Q24311228 | ||
| Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I | Q24312113 | ||
| Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1 | Q24318342 | ||
| PACT, a protein activator of the interferon-induced protein kinase, PKR. | Q24319677 | ||
| Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein | Q24536345 | ||
| Modular structure of PACT: distinct domains for binding and activating PKR | Q24551001 | ||
| 5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I | Q24653786 | ||
| Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action | Q24672548 | ||
| The structure of a biologically active influenza virus ribonucleoprotein complex | Q27316702 | ||
| The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors | Q39685168 | ||
| Role of murine cytomegalovirus US22 gene family members in replication in macrophages | Q39748997 | ||
| Essential role for either TRS1 or IRS1 in human cytomegalovirus replication | Q39884830 | ||
| Cytosolic viral sensor RIG-I is a 5'-triphosphate-dependent translocase on double-stranded RNA. | Q39899310 | ||
| Protein kinase R reveals an evolutionary model for defeating viral mimicry | Q39910707 | ||
| NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription | Q39960501 | ||
| 5'-triphosphate-dependent activation of PKR by RNAs with short stem-loops | Q40042442 | ||
| Synthetic polynucleotides. | Q40047927 | ||
| Paramyxovirus-induced shutoff of host and viral protein synthesis: role of the P and V proteins in limiting PKR activation | Q40058131 | ||
| Tula and Puumala hantavirus NSs ORFs are functional and the products inhibit activation of the interferon-beta promoter | Q40092449 | ||
| A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis | Q40167332 | ||
| The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner | Q40174839 | ||
| IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein | Q40202119 | ||
| The (2'-5')Oligoadenylate (pppA2'-5'A2'-5'A) Synthetase and Protein Kinase(s) from Interferon-Treated Cells | Q40210116 | ||
| The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF-3 and beta interferon promoter activation | Q40213877 | ||
| Plus and minus strand leader rnas in negative strand virus-infected cells | Q40279841 | ||
| A cluster of dispensable genes within the human cytomegalovirus genome short component: IRS1, US1 through US5, and the US6 family | Q40308946 | ||
| Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. | Q40319046 | ||
| A C-terminal basic amino acid motif of Zaire ebolavirus VP35 is essential for type I interferon antagonism and displays high identity with the RNA-binding domain of another interferon antagonist, the NS1 protein of influenza A virus | Q40508331 | ||
| Inhibition of RNA polymerase II phosphorylation by a viral interferon antagonist | Q40554311 | ||
| The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein | Q40576311 | ||
| The influenza B virus nonstructural NS1 protein is essential for efficient viral growth and antagonizes beta interferon induction | Q40594978 | ||
| The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans | Q40708939 | ||
| Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus | Q40713530 | ||
| Mutations in the measles virus C protein that up regulate viral RNA synthesis | Q40797848 | ||
| Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase | Q40858827 | ||
| Influenza virus NS1 protein alters the subnuclear localization of cellular splicing components | Q41352003 | ||
| Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase | Q41613759 | ||
| Roles of the influenza virus polymerase and nucleoprotein in forming a functional RNP structure | Q41845291 | ||
| Interactions between double-stranded RNA regulators and the protein kinase DAI | Q41845602 | ||
| Double-stranded RNA binding by human cytomegalovirus pTRS1. | Q42147481 | ||
| Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanism | Q42158761 | ||
| Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses | Q42425012 | ||
| Human cytomegalovirus TRS1 and IRS1 gene products block the double-stranded-RNA-activated host protein shutoff response induced by herpes simplex virus type 1 infection | Q42589554 | ||
| Specific inhibition of the PKR-mediated antiviral response by the murine cytomegalovirus proteins m142 and m143. | Q42806112 | ||
| Translational insensitivity to potent activation of PKR by HCV IRES RNA. | Q42987940 | ||
| Immunofluorescent demonstration of double-stranded RNA and virus antigen in RNA virus-infected cells | Q42995840 | ||
| Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA. | Q43860103 | ||
| HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes. | Q44373349 | ||
| Biochemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase | Q44539835 | ||
| Characterization of rubella virus replication complexes using antibodies to double-stranded RNA. | Q44565475 | ||
| The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing | Q45345426 | ||
| Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor | Q45772727 | ||
| Immunofluorescent demonstration of double-stranded RNA in the cytoplasm of Sindbis virus-infected cells | Q45814398 | ||
| Binding of influenza A virus NS1 protein to dsRNA in vitro | Q45869820 | ||
| Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR | Q27316764 | ||
| Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells | Q27469379 | ||
| Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNA | Q27472970 | ||
| The S Segment of Punta Toro Virus (Bunyaviridae, Phlebovirus) Is a Major Determinant of Lethality in the Syrian Hamster and Codes for a Type I Interferon Antagonist | Q27478045 | ||
| La Crosse Bunyavirus Nonstructural Protein NSs Serves To Suppress the Type I Interferon System of Mammalian Hosts | Q27480353 | ||
| Ultrastructure of Kunjin virus-infected cells: colocalization of NS1 and NS3 with double-stranded RNA, and of NS2B with NS3, in virus-induced membrane structures | Q27480850 | ||
| Visualization of Double-Stranded RNA in Cells Supporting Hepatitis C Virus RNA Replication | Q27485448 | ||
| Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction | Q27485881 | ||
| Interferon-inducible antiviral effectors | Q27486790 | ||
| Structural features of an influenza virus promoter and their implications for viral RNA synthesis | Q27634807 | ||
| Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses | Q27644686 | ||
| RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates | Q27861007 | ||
| 5'-Triphosphate RNA is the ligand for RIG-I | Q28131726 | ||
| Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR | Q28217791 | ||
| The multifunctional NS1 protein of influenza A viruses | Q28294201 | ||
| Translational control in mammalian cells | Q28295830 | ||
| The dsRNA protein kinase PKR: virus and cell control | Q28298945 | ||
| Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery | Q28475642 | ||
| Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication. | Q28609759 | ||
| Multiple anti-interferon actions of the influenza A virus NS1 protein | Q30361157 | ||
| P58(IPK): a novel "CIHD" member of the host innate defense response against pathogenic virus infection. | Q30377393 | ||
| Preventing nondesired RNA-primed RNA extension catalyzed by T7 RNA polymerase. | Q31136120 | ||
| Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR. | Q31778073 | ||
| Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1 | Q33195896 | ||
| Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response | Q33278262 | ||
| Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation | Q33406230 | ||
| In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin | Q33633828 | ||
| Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems | Q33653597 | ||
| Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain | Q33781751 | ||
| The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus. | Q33811639 | ||
| Viral double-stranded RNA, cytokines, and the flu. | Q33890185 | ||
| Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products | Q34208420 | ||
| The role of PACT in mediating gene induction, PKR activation, and apoptosis in response to diverse stimuli | Q34248644 | ||
| Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR | Q57236274 | ||
| Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition | Q57236276 | ||
| Autophosphorylation of the protein kinase dependent on double-stranded RNA | Q68778559 | ||
| The double-stranded RNA-dependent protein kinase is also activated by heparin | Q69397069 | ||
| Immunofluorescent localization of double-stranded RNA in reovirus-infected cells | Q69909642 | ||
| The RNA-binding and effector domains of the viral NS1 protein are conserved to different extents among influenza A and B viruses | Q71530228 | ||
| Interferon-responsive protein kinase (p68) and proliferating cell nuclear antigen are inversely distributed in head and neck squamous cell carcinoma | Q74014805 | ||
| Mechanism of interferon action: functional characterization of positive and negative regulatory domains that modulate transcriptional activation of the human RNA-dependent protein kinase Pkr promoter | Q77933422 | ||
| The Th2 transcription factor c-Maf inhibits IL-12p35 gene expression in activated macrophages by targeting NF-kappaB nuclear translocation | Q95827929 | ||
| On the discovery of interferon-inducible, double-stranded RNA activated enzymes: the 2'-5'oligoadenylate synthetases and the protein kinase PKR. | Q36903412 | ||
| Sendai virus C protein plays a role in restricting PKR activation by limiting the generation of intracellular double-stranded RNA. | Q36933945 | ||
| Beyond double-stranded RNA-type I IFN induction by 3pRNA and other viral nucleic acids | Q36985388 | ||
| Protein kinase PKR mediates the apoptosis induction and growth restriction phenotypes of C protein-deficient measles virus | Q37033277 | ||
| Analysis of influenza B Virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains | Q37033318 | ||
| TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress | Q37033570 | ||
| Binding and relocalization of protein kinase R by murine cytomegalovirus | Q37099753 | ||
| Ebola virus VP35 antagonizes PKR activity through its C-terminal interferon inhibitory domain | Q37333731 | ||
| Toll-like receptor and RIG-I-like receptor signaling | Q37348422 | ||
| Approaching the RNA ligand for RIG-I? | Q37361445 | ||
| RNA dimerization promotes PKR dimerization and activation | Q37389973 | ||
| Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. | Q37879797 | ||
| Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein. | Q38287391 | ||
| Translational control by influenza virus. Identification of cis-acting sequences and trans-acting factors which may regulate selective viral mRNA translation | Q38288951 | ||
| Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein | Q38610343 | ||
| Double-stranded RNA binding by a heterodimeric complex of murine cytomegalovirus m142 and m143 proteins | Q38761545 | ||
| NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase | Q39195523 | ||
| Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of alpha/beta interferon | Q39320757 | ||
| Binding and nuclear relocalization of protein kinase R by human cytomegalovirus TRS1. | Q39321563 | ||
| Mutant human cytomegalovirus lacking the immediate-early TRS1 coding region exhibits a late defect | Q34360380 | ||
| RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids | Q34361738 | ||
| Genomic RNAs of influenza viruses are held in a circular conformation in virions and in infected cells by a terminal panhandle | Q34367296 | ||
| When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA. | Q34380769 | ||
| Structure of the vesicular stomatitis virus nucleoprotein-RNA complex | Q34538707 | ||
| Crystal structure of the rabies virus nucleoprotein-RNA complex | Q34538715 | ||
| The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway | Q34598589 | ||
| Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling | Q34648134 | ||
| Structural mechanism of RNA recognition by the RIG-I-like receptors | Q34808213 | ||
| Activation of PKR by Bunyamwera virus is independent of the viral interferon antagonist NSs. | Q34975543 | ||
| Murine cytomegalovirus m142 and m143 are both required to block protein kinase R-mediated shutdown of protein synthesis | Q35101535 | ||
| The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. | Q35105093 | ||
| Synthesis of complementary RNA sequences during productive adenovirus infection | Q35120191 | ||
| Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors. | Q35125960 | ||
| The Ebola virus VP35 protein functions as a type I IFN antagonist. | Q35422223 | ||
| RNA template-directed RNA synthesis by T7 RNA polymerase | Q35607261 | ||
| Influenza virus targets the mRNA export machinery and the nuclear pore complex | Q35629429 | ||
| The VP35 protein of Ebola virus inhibits the antiviral effect mediated by double-stranded RNA-dependent protein kinase PKR. | Q35634367 | ||
| Monoclonal antibodies to double-stranded RNA as probes of RNA structure in crude nucleic acid extracts | Q35766226 | ||
| The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism | Q35784635 | ||
| Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses | Q35785139 | ||
| Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAs | Q35837862 | ||
| Type 1 interferons and the virus-host relationship: a lesson in détente . | Q36475884 | ||
| Inhibition of PKR by RNA and DNA viruses | Q36480640 | ||
| Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus | Q36484103 | ||
| RNA synthesis in cells infected with herpes simplex virus. X. Properties of viral symmetric transcripts and of double-stranded RNA prepared from them | Q36533025 | ||
| Mechanism of Synthesis of Vaccinia Virus Double-Stranded Ribonucleic Acid In Vivo and In Vitro | Q36577589 | ||
| The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A) | Q36632150 | ||
| Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNA | Q36641030 | ||
| Nucleoside modifications modulate activation of the protein kinase PKR in an RNA structure-specific manner | Q36666260 | ||
| Activation of PKR: an open and shut case? | Q36695833 | ||
| Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases | Q36784349 | ||
| The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation. | Q36827533 | ||
| Cellular La protein shields nonsegmented negative-strand RNA viral leader RNA from RIG-I and enhances virus growth by diverse mechanisms. | Q36845620 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 3 | |
| P304 | page(s) | 523-544 | |
| P577 | publication date | 2009-10-27 | |
| P1433 | published in | Viruses | Q7935305 |
| P1476 | title | Activation of the Antiviral Kinase PKR and Viral Countermeasures | |
| P478 | volume | 1 |
| Q33831715 | 'Black sheep' that don't leave the double-stranded RNA-binding domain fold |
| Q35652151 | A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins. |
| Q37718042 | ADAR1 and PACT contribute to efficient translation of transcripts containing HIV-1 trans-activating response (TAR) element. |
| Q92564618 | ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity |
| Q37015864 | Activation of PKR by short stem-loop RNAs containing single-stranded arms |
| Q92072181 | Adenovirus VA RNAI Blocks ASC Oligomerization and Inhibits NLRP3 Inflammasome Activation |
| Q33359465 | Andes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis |
| Q37985804 | Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury |
| Q35961375 | Baculovirus protein PK2 subverts eIF2α kinase function by mimicry of its kinase domain C-lobe. |
| Q39274197 | Chemoproteomic profiling identifies changes in DNA-PK as markers of early dengue virus infection |
| Q35701896 | Complementation of the human adenovirus type 5 VA RNAI defect by the Vaccinia virus E3L protein and serotype-specific VA RNAIs |
| Q27349527 | Coronavirus gene 7 counteracts host defenses and modulates virus virulence |
| Q35109562 | De novo assembly and transcriptome analysis of Atlantic salmon macrophage/dendritic-like TO cells following type I IFN treatment and Salmonid alphavirus subtype-3 infection |
| Q66680693 | Decoding type I and III interferon signalling during viral infection |
| Q40059121 | Die Another Day: Inhibition of Cell Death Pathways by Cytomegalovirus. |
| Q38419101 | Early IFN type I response: Learning from microbial evasion strategies |
| Q37174456 | Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions |
| Q37055225 | Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-κB1 p105 complex in co-transfected HEK-293 cells |
| Q64252262 | Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections |
| Q40132236 | Filovirus Strategies to Escape Antiviral Responses |
| Q38631753 | Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells |
| Q47097744 | Host Cell Restriction Factors that Limit Influenza A Infection. |
| Q38714315 | Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR. |
| Q38862108 | Innate immune evasion strategies of DNA and RNA viruses |
| Q36434332 | Knockout of the Host Resistance Gene Pkr Fully Restores Replication of Murine Cytomegalovirus m142 and m143 Mutants In Vivo |
| Q35792819 | MP-12 virus containing the clone 13 deletion in the NSs gene prevents lethal disease when administered after Rift Valley fever virus infection in hamsters |
| Q92879458 | Mammalian orthoreovirus Infection is Enhanced in Cells Pre-Treated with Sodium Arsenite |
| Q59353567 | Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner |
| Q35751132 | Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE. |
| Q41926832 | NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR. |
| Q37049980 | PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells |
| Q35549258 | Potential role for snoRNAs in PKR activation during metabolic stress |
| Q40695558 | Pre-immune state induced by chicken interferon gamma inhibits the replication of H1N1 human and H9N2 avian influenza viruses in chicken embryo fibroblasts |
| Q111459478 | RNA–protein interactomes as invaluable resources to study RNA viruses: Insights from SARS CoV‐2 studies |
| Q27010116 | Recognition of human oncogenic viruses by host pattern-recognition receptors |
| Q99238128 | Rescue of a Vaccinia Virus Mutant Lacking IFN Resistance Genes K1L and C7L by the Parapoxvirus Orf Virus |
| Q36301254 | The Regulatory and Kinase Domains but Not the Interdomain Linker Determine Human Double-stranded RNA-activated Kinase (PKR) Sensitivity to Inhibition by Viral Non-coding RNAs |
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| Q40283972 | The cell biology of Chikungunya virus infection |
| Q38256883 | The influence of viral RNA secondary structure on interactions with innate host cell defences. |
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