Small molecule inhibitors of BRAF in clinical trials

scientific article published on 03 December 2011

Small molecule inhibitors of BRAF in clinical trials is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BMCL.2011.11.060
P698PubMed publication ID22222036
P5875ResearchGate publication ID221726447

P50authorRichard MaraisQ30118915
Caroline J SpringerQ55446346
Alfonso ZambonQ55446347
P2093author name stringIon Niculescu-Duvaz
Dan Niculescu-Duvaz
P2860cites workMelanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulationQ24629474
Mutations of the BRAF gene in human cancerQ27860760
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages4
P304page(s)789-792
P577publication date2011-12-03
P1433published inBioorganic & Medicinal Chemistry LettersQ2709483
P1476titleSmall molecule inhibitors of BRAF in clinical trials
P478volume22

Reverse relations

cites work (P2860)
Q48111405Access to π-conjugated azaindole derivatives via rhodium(iii)-catalyzed cascade reaction of azaindoles and diazo compounds.
Q58712892Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells
Q64055605Clinical development of targeted and immune based anti-cancer therapies
Q36189476Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization
Q42106395Effects of RAF inhibitors on PI3K/AKT signalling depend on mutational status of the RAS/RAF signalling axis
Q36864736Evolving approaches to patients with advanced differentiated thyroid cancer
Q33632493Identification and synthesis of N-(thiophen-2-yl) benzamide derivatives as BRAF(V600E) inhibitors
Q27678754Identification of a Novel Family of BRAF V600E Inhibitors
Q39069541Identification of type II inhibitors targeting BRAF using privileged pharmacophores
Q39022580In silico identification of novel kinase inhibitors by targeting B-Raf(v660e) from natural products database
Q35434188Multitarget inhibitors derived from crosstalk mechanism involving VEGFR2.
Q38238612One Hippo and many masters: differential regulation of the Hippo pathway in cancer
Q27696222Optimization of diarylthiazole B-raf inhibitors: identification of a compound endowed with high oral antitumor activity, mitigated hERG inhibition, and low paradoxical effect
Q49021003Pan-Raf co-operates with PI3K-dependent signalling and critically contributes to myeloma cell survival independently of mutated RAS.
Q34347917Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors.
Q35847321The immune-related role of BRAF in melanoma