Temozolomide dosing regimens for glioma patients

scientific article published on June 2012

Temozolomide dosing regimens for glioma patients is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S11910-012-0262-Y
P698PubMed publication ID22437507

P2093author name stringBart Neyns
Bernd Kaina
Christine Marosi
Herwig M Strik
P2860cites workProcessing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cyclesQ43218101
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomideQ43245397
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiformeQ45163828
Predictive impact of MGMT promoter methylation in glioblastoma of the elderlyQ45416568
Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final reportQ46364938
Temozolomide three weeks on and one week off as first line therapy for patients with recurrent or progressive low grade gliomasQ46630773
A multicenter cohort study of dose-dense temozolomide (21 of 28 days) for the treatment of recurrent anaplastic astrocytoma or oligoastrocytoma.Q46720231
Efficacy and tolerability of temozolomide in an alternating weekly regimen in patients with recurrent gliomaQ48090038
Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group studyQ48371882
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Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanineQ48479768
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MGMT gene silencing and benefit from temozolomide in glioblastomaQ27824832
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastomaQ27860910
A phase II study of extended low-dose temozolomide in recurrent malignant gliomasQ28344315
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trialQ29547224
Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomasQ30442049
Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: a Medical Research Council trialQ32034410
Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedulesQ33347264
Extended-schedule dose-dense temozolomide in refractory gliomasQ33385736
Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trialQ33395957
Randomized comparisons of radiotherapy and nitrosoureas for the treatment of malignant glioma after surgeryQ33483488
A phase I trial of weekly lomustine in patients with advanced cancerQ33493359
Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomideQ33699572
MGMT: its role in cancer aetiology and cancer therapeuticsQ34310201
MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agentsQ34626127
A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastomaQ34992535
DNA repair in resistance to alkylating anticancer drugsQ35017573
Neuro-Oncology Working Group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant gliomaQ35208736
Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase II study from gruppo italiano cooperativo di neuro-oncologia (GICNO).Q36611825
MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastomaQ39743920
Temozolomide rechallenge in recurrent malignant glioma by using a continuous temozolomide schedule: the "rescue" approachQ40053895
Rechallenge with temozolomide with different scheduling is effective in recurrent malignant gliomasQ42743277
Temozolomide versus procarbazine, lomustine, and vincristine in recurrent high-grade glioma.Q42882364
O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastomaQ43128475
P433issue3
P921main subjecttemozolomideQ425088
P304page(s)286-293
P577publication date2012-06-01
P1433published inCurrent Neurology and Neuroscience ReportsQ18206211
P1476titleTemozolomide dosing regimens for glioma patients
P478volume12

Reverse relations

cites work (P2860)
Q88030103A guide for the analysis of long-term population growth in cancer
Q52644558An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.
Q64107495Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide?
Q42237770Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence
Q33920087Case Report: Pregnancy in a patient with recurrent glioblastoma
Q35920319Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients
Q38833453Combined Delivery of Temozolomide and Anti-miR221 PNA Using Mesoporous Silica Nanoparticles Induces Apoptosis in Resistant Glioma Cells
Q33757933Conditioned media from human adipose tissue-derived mesenchymal stem cells and umbilical cord-derived mesenchymal stem cells efficiently induced the apoptosis and differentiation in human glioma cell lines in vitro
Q48763582Low Dose of Doxorubicin Potentiates the Effect of Temozolomide in Glioblastoma Cells
Q35234429Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation
Q57461797Sensitivity of CD3/CD28-stimulated versus non-stimulated lymphocytes to ionizing radiation and genotoxic anticancer drugs: key role of ATM in the differential radiation response
Q43092195Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways
Q36288254The metalloprotease-disintegrin ADAM8 contributes to temozolomide chemoresistance and enhanced invasiveness of human glioblastoma cells.
Q38738437The regrowth kinetic of the surviving population is independent of acute and chronic responses to temozolomide in glioblastoma cell lines
Q26863755Treating malignant glioma in Chinese patients: update on temozolomide

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