Importance of myocyte-nonmyocyte interactions in cardiac development and disease

scientific article published on March 2012

Importance of myocyte-nonmyocyte interactions in cardiac development and disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/CIRCRESAHA.111.243899
P932PMC publication ID3366271
P698PubMed publication ID22461366

P2093author name stringEdward E Morrisey
Ying Tian
P2860cites workFoxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanismsQ24296379
Notch signaling is essential for ventricular chamber developmentQ24299001
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytesQ24308695
Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineagesQ24310167
Cardiomyocytes as effectors of nitric oxide signallingQ24310604
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formationQ24316945
Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in miceQ24338200
Development of the endocardiumQ27692614
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injuryQ28252995
Beta-catenin overexpression reduces myocardial infarct size through differential effects on cardiomyocytes and cardiac fibroblastsQ28258964
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repairQ28295270
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesisQ28300359
miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodelingQ28304542
Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in XenopusQ28307143
Fibroblast growth factor-2 mediates pressure-induced hypertrophic responseQ28343582
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterningQ28504579
Neuregulin-1 promotes formation of the murine cardiac conduction systemQ28507021
Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closureQ28507430
Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant miceQ28508475
Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarctionQ28508856
Double-outlet right ventricle and overriding tricuspid valve reflect disturbances of looping, myocardialization, endocardial cushion differentiation, and apoptosis in TGF-beta(2)-knockout miceQ28509033
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptorQ28509287
Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular developmentQ28511544
Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repairQ28587325
Multiple essential functions of neuregulin in developmentQ28587914
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformationQ28589469
Placental expression of angiopoietin-1, angiopoietin-2 and tie-2 during placental development in an ovine model of placental insufficiency-fetal growth restriction.Q46342914
Heart failure associated with sunitinib malate: a multitargeted receptor tyrosine kinase inhibitorQ46665977
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulatorsQ46742633
The wingless signaling pathway is directly involved in Drosophila heart developmentQ47072326
The Wnt/beta-catenin pathway regulates cardiac valve formationQ47073676
Transcriptional regulation of cardiac progenitor cell populationsQ47225116
Wnt11 and Wnt7a are up-regulated in association with differentiation of cardiac conduction cells in vitro and in vivo.Q47312606
Reduction of infarct size and prevention of cardiac rupture in transgenic mice overexpressing FrzA.Q47438866
Angiopoietin 1 expression levels in the myocardium direct coronary vessel developmentQ48020368
Experimental analyses of the function of the proepicardium using a new microsurgical procedure to induce loss-of-proepicardial-function in chick embryosQ48745106
Cellular pattern of insulin-like growth factor-I (IGF-I) and type I IGF receptor gene expression in early organogenesis: comparison with IGF-II gene expressionQ48909407
The fate diversity of mesodermal cells within the heart field during chicken early embryogenesisQ49121763
Notch1b and neuregulin are required for specification of central cardiac conduction tissue.Q52025862
Epicardium is required for the full rate of myocyte proliferation and levels of expression of myocyte mitogenic factors FGF2 and its receptor, FGFR-1, but not for transmural myocardial patterning in the embryonic chick heart.Q52099714
Evidence for novel fate of Flk1+ progenitor: contribution to muscle lineage.Q52107873
Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development.Q52174314
Bone morphogenetic protein-2 acts synergistically with transforming growth factor-beta3 during endothelial-mesenchymal transformation in the developing chick heart.Q52176538
TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart.Q52178122
An autocrine function for transforming growth factor beta 3 in the atrioventricular endocardial cushion tissue formation during chick heart development.Q52180208
Involvement of FrzA/sFRP-1 and the Wnt/frizzled pathway in ischemic preconditioning.Q52564453
Neuregulin 1 sustains the gene regulatory network in both trabecular and nontrabecular myocardium.Q53310950
Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair.Q53540644
Pericardial mesoderm generates a population of coronary smooth muscle cells migrating into the heart along with ingrowth of the epicardial organ.Q53678848
Formation of the tricuspid valve in the human heart.Q54017392
Early development of quail heart epicardium and associated vascular and glandular structures.Q54042502
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overloadQ57396501
Heart conduction system: a neural crest derivative?Q57973429
Thymosin β4 facilitates epicardial neovascularization of the injured adult heartQ58200964
Thymosin beta4 and cardiac repair.Q64977201
Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A)Q68581207
Neurofilament proteins are co-expressed with desmin in heart conduction system myocytesQ68631637
Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor betaQ69650317
Distribution of conduction system fibers in the developing and adult rabbit heart revealed by an antineurofilament antibodyQ69664235
The origin of the epicardium and the embryonic myocardial circulation in the mouseQ70993615
Fate diversity of primitive streak cells during heart field formation in ovoQ73205746
In vivo induction of cardiac Purkinje fiber differentiation by coexpression of preproendothelin-1 and endothelin converting enzyme-1Q74025403
Origin of coronary endothelial cells from epicardial mesothelium in avian embryosQ78810466
Pressure overload-induced transient oxidative stress mediates perivascular inflammation and cardiac fibrosis through angiotensin IIQ79649271
Expression of Dishevelled-1 in wound healing after acute myocardial infarction: possible involvement in myofibroblast proliferation and migrationQ80345305
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factorsQ28589872
Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivoQ28590848
TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypesQ28592444
Failure of blood-island formation and vasculogenesis in Flk-1-deficient miceQ28593600
MicroRNA-133 controls cardiac hypertrophyQ29616572
Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress.Q30492863
BMP signals promote proepicardial protrusion necessary for recruitment of coronary vessel and epicardial progenitors to the heartQ30496194
FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardiumQ30502384
Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overloadQ33215759
Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overloadQ33559670
Intramyocardial fibroblast myocyte communicationQ33586605
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP).Q33823445
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate.Q33997854
The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosisQ34112864
Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair.Q34232889
Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formationQ34234421
Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages.Q34297652
Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarctionQ34397290
Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineagesQ34579177
Development of the coronary vessel systemQ34986182
Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicityQ35035923
Neuregulins: functions, forms, and signaling strategiesQ35089314
Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overloadQ35095396
The epicardium and epicardially derived cells (EPDCs) as cardiac stem cellsQ35618207
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in miceQ36099401
Epicardium-derived progenitor cells require beta-catenin for coronary artery formationQ36156815
Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heartQ36239617
Endothelin-induced conversion of embryonic heart muscle cells into impulse-conducting Purkinje fibersQ36490548
Induction of Purkinje fiber differentiation by coronary arterializationQ36668306
Development of the cardiac conduction system.Q36731738
Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failureQ36914725
Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart.Q36952843
Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewalQ37080793
Role of insulin-like growth factor 1 and phosphoinositide 3-kinase in a setting of heart diseaseQ37091119
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinibQ37098098
Embryonic development of the proepicardium and coronary vesselsQ37098811
Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repairQ37101612
Endothelial cell lineages of the heartQ37235964
Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3aQ37260268
Fibroblast growth factor 2 control of vascular toneQ37362801
Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antisense oligodeoxynucleotide to transforming growth factor beta 3.Q37408356
Endothelium-driven myocardial growth or nitric oxide at the crossroads.Q37432852
Origin of cardiac fibroblasts and the role of periostinQ37628341
Cell communications in the heart.Q37784108
Cellular Interplay between Cardiomyocytes and Nonmyocytes in Cardiac Remodeling.Q38509926
TGF-beta1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II.Q39737677
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heartQ40036277
Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular diseaseQ40488319
Does the subepicardial mesenchyme contribute myocardioblasts to the myocardium of the chick embryo heart? A quail-chick chimera study tracing the fate of the epicardial primordiumQ40810484
Epicardium-derived cells contribute a novel population to the myocardial wall and the atrioventricular cushionsQ41035429
Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouseQ41161285
Requirement for neuregulin receptor erbB2 in neural and cardiac developmentQ41269625
The cardiac endothelium: functional morphology, development, and physiologyQ41274664
Clonal analysis of cardiac morphogenesis in the chicken embryo using a replication‐defective retrovirus. III: Polyclonal origin of adjacent ventricular myocytesQ41602379
The use of replication-defective retroviruses for cell lineage studies of myogenic cellsQ41649812
Synergistic roles of neuregulin-1 and insulin-like growth factor-I in activation of the phosphatidylinositol 3-kinase pathway and cardiac chamber morphogenesisQ41708926
Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouseQ41831039
WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways.Q42100794
Platelet-derived growth factor receptor beta signaling is required for efficient epicardial cell migration and development of two distinct coronary vascular smooth muscle cell populationsQ42114294
Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling.Q42137346
CTGF expression is induced by TGF- beta in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosisQ42494057
Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.Q42504195
Beta-catenin, an inducer of uncontrolled cell proliferation and migration in malignancies, is localized in the cytoplasm of vascular endothelium during neovascularization after myocardial infarctionQ42757145
Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transitionQ42775592
Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse heartsQ42946844
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signalingQ43152071
Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarctionQ43162631
Fibroblast growth factor (FGF)-4 can induce proliferation of cardiac cushion mesenchymal cells during early valve leaflet formationQ44472622
Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-beta 1 and endothelin-1 from fibroblastsQ46061333
The zebrafish gene cloche acts upstream of a flk-1 homologue to regulate endothelial cell differentiationQ46061948
Common epicardial origin of coronary vascular smooth muscle, perivascular fibroblasts, and intermyocardial fibroblasts in the avian heartQ46186694
Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinomaQ46329140
P433issue7
P304page(s)1023-1034
P577publication date2012-03-01
P1433published inCirculation ResearchQ2599020
P1476titleImportance of myocyte-nonmyocyte interactions in cardiac development and disease
P478volume110

Reverse relations

cites work (P2860)
Q92525212A Light Wand to Untangle the Myocardial Cell Network
Q27330969A Systemized Approach to Investigate Ca(2+) Synchronization in Clusters of Human Induced Pluripotent Stem-Cell Derived Cardiomyocytes
Q28511530A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development
Q41196397A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.
Q34675044Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway
Q26770294Cardiac Extracellular Vesicles in Normal and Infarcted Heart
Q90402112Cardiac Stem Cells in the Postnatal Heart: Lessons from Development
Q36462525Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish
Q38044304Cardiac myocyte-fibroblast interactions and the coronary vasculature
Q55403102Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis.
Q62923934Cardiomyocyte-Endothelial Cell Interactions in Cardiac Remodeling and Regeneration
Q47763409Cardioprotective Effects of Exosomes and Their Potential Therapeutic Use.
Q38171770Cell sheet-based cardiac tissue engineering
Q41976316Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome
Q39741408Constitutive Expression of a Dominant-Negative TGF-β Type II Receptor in the Posterior Left Atrium Leads to Beneficial Remodeling of Atrial Fibrillation Substrate.
Q27021613Cross talk between cardiac myocytes and fibroblasts: from multiscale investigative approaches to mechanisms and functional consequences
Q30838004Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues
Q36977627Differential effects of retinoids and inhibitors of ERK and p38 signaling on adipogenic and myogenic differentiation of P19 stem cells
Q52715170Directed fusion of cardiac spheroids into larger heterocellular microtissues enables investigation of cardiac action potential propagation via cardiac fibroblasts.
Q92309729Exosomal circHIPK3 Released from Hypoxia-Pretreated Cardiomyocytes Regulates Oxidative Damage in Cardiac Microvascular Endothelial Cells via the miR-29a/IGF-1 Pathway
Q50243885Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis
Q35892259Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss.
Q38184790Fibroblast-mediated pathways in cardiac hypertrophy
Q37255246Fibroblast-myocyte coupling in the heart: Potential relevance for therapeutic interventions
Q26851548GRK2 in the heart: a GPCR kinase and beyond
Q97517219Human Cardiac Mesenchymal Stromal Cells From Right and Left Ventricles Display Differences in Number, Function, and Transcriptomic Profile
Q34599920Jun is required in Isl1-expressing progenitor cells for cardiovascular development
Q37342086Lack of specificity of fibroblast-specific protein 1 in cardiac remodeling and fibrosis
Q89927377Local and sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischemic injury
Q38184460Microvesicles and exosomes for intracardiac communication
Q64059811Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration
Q35966000Modulation of cardiac fibrosis by Krüppel-like factor 6 through transcriptional control of thrombospondin 4 in cardiomyocytes.
Q38320233Molecular regulation of cardiomyocyte differentiation
Q92922799Multi-cellularity in cardiac tissue engineering, how close are we to native heart tissue?
Q36497186New approaches under development: cardiovascular embryology applied to heart disease.
Q34717025Pathologic function and therapeutic potential of exosomes in cardiovascular disease
Q42378811Prokineticin receptor-1-dependent paracrine and autocrine pathways control cardiac tcf21+ fibroblast progenitor cell transformation into adipocytes and vascular cells
Q30586973ROS regulate cardiac function via a distinct paracrine mechanism.
Q38193013ROS signalling between endothelial cells and cardiac cells
Q41336885Re-evaluation of hypoplastic left heart syndrome from a developmental and morphological perspective
Q41089472Regulation of cardiomyocyte behavior in zebrafish trabeculation by Neuregulin 2a signaling
Q27319491RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway
Q60927424The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling
Q26770162The force within: endocardial development, mechanotransduction and signalling during cardiac morphogenesis
Q35118478The role of the protein tyrosine phosphatase SHP2 in cardiac development and disease.
Q104060465The role of vascular niche and endothelial cells in organogenesis and regeneration
Q26799470Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening
Q38709842Transcriptome profiling of 3D co-cultured cardiomyocytes and endothelial cells under oxidative stress using a photocrosslinkable hydrogel system
Q47385929Understanding the role of mammalian sterile 20-like kinase 1 (MST1) in cardiovascular disorders
Q52656929Zinc and Zinc Transporters: Novel Regulators of Ventricular Myocardial Development.
Q38607511β-Catenin stabilization promotes proliferation and increase in cardiomyocyte number in chick embryonic epicardial explant culture

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