microRNAs in cancer management.

scientific article published on June 2012

microRNAs in cancer management. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S1470-2045(12)70073-6
P698PubMed publication ID22652233
P5875ResearchGate publication ID225087528

P50authorThomas J JacksonQ59784596
P2093author name stringMartin Bushell
David Ferland-McCollough
Yi W Kong
P2860cites workMiRNA-directed regulation of VEGF and other angiogenic factors under hypoxiaQ21092263
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1Q21092854
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesisQ24293460
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulatorsQ24336898
miR-15 and miR-16 induce apoptosis by targeting BCL2Q24536069
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
miRNA and vascular cell movementQ24598174
Repression of versican expression by microRNA-143Q24607134
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44Q24617130
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancersQ24625794
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genesQ24628676
MicroRNA-132–mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesisQ24634064
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferationQ24645026
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtypeQ24646090
miR-19 is a key oncogenic component of mir-17-92Q24652326
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinomaQ24653676
A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer riskQ24655762
Circulating microRNAs, potential biomarkers for drug-induced liver injuryQ24656209
A Variant in a MicroRNA complementary site in the 3' UTR of the KIT oncogene increases risk of acral melanomaQ27851611
MicroRNA gene expression deregulation in human breast cancerQ27860690
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cellsQ27860960
c-Myc-regulated microRNAs modulate E2F1 expressionQ27861046
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1Q27861068
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNAQ27861124
The role of let-7 in cell differentiation and cancerQ28259549
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cellsQ28262214
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemiaQ28279141
Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cellsQ28283249
p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replicationQ28587920
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosisQ29547575
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasmaQ29547772
Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphomaQ29614238
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infectionQ29615959
miR-21-mediated tumor growthQ29616149
The microRNA spectrum in 12 body fluidsQ29618068
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cellsQ29619847
microRNAs as oncogenes and tumor suppressorsQ29619907
Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosisQ30004190
Global microRNA expression profiling identifies MiR-210 associated with tumor proliferation, invasion and poor clinical outcome in breast cancerQ31022382
Detection of tumor marker CA125 in ovarian carcinoma using quantum dotsQ31120718
Antagomir-mediated silencing of endothelial cell specific microRNA-126 impairs ischemia-induced angiogenesisQ33397113
Analysis of microRNAs in pancreatic fine-needle aspirates can classify benign and malignant tissuesQ33693132
Selective release of microRNA species from normal and malignant mammary epithelial cellsQ33728084
A pilot study of circulating miRNAs as potential biomarkers of early stage breast cancerQ33742015
Fecal MicroRNAs as novel biomarkers for colon cancer screeningQ33981746
Overexpression of members of the microRNA-183 family is a risk factor for lung cancer: a case control studyQ34020155
MicroRNAs associated with metastatic prostate cancerQ34042888
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.Q34130311
LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.Q34359833
MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migrationQ34426103
Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.Q34783833
Diagnostic assay based on hsa-miR-205 expression distinguishes squamous from nonsquamous non-small-cell lung carcinoma.Q34959865
A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancerQ34976475
Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implicationsQ35086100
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in miceQ35086711
Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus miceQ35673271
Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growthQ35846712
Nanoparticle and targeted systems for cancer therapyQ35879221
mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerQ36103305
MicroRNA-cancer connection: the beginning of a new taleQ36555283
MicroRNA expression profiling in cancer from a bioinformatics prospectiveQ37004629
The role of HER2 in early breast cancer metastasis and the origins of resistance to HER2-targeted therapiesQ37326072
Karyotype-specific microRNA signature in chronic lymphocytic leukemiaQ37412319
Gene-expression-based prognostic assays for breast cancerQ37741797
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathwaysQ37820099
Cancer stem cells and cancer therapyQ37841186
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growthQ38298486
Circulating microRNAs as novel minimally invasive biomarkers for breast cancerQ39281588
Smart nanocarrier based on PEGylated hyaluronic acid for cancer therapyQ39464045
Overexpression of miR-429 induces mesenchymal-to-epithelial transition (MET) in metastatic ovarian cancer cellsQ39601112
Fluorescent nanocrystals for use in early cervical cancer detectionQ40378537
Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dotsQ42807706
Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancerQ43539336
MiR-30 family and EMT in human fetal pancreatic isletsQ43565364
MiR-96 and miR-183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytologyQ44613300
Unlocked nucleic acid (UNA) and UNA derivatives: thermal denaturation studiesQ46384202
Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.Q48054446
Cytomorphologic differentiation of benign and malignant mammary tumors in fine needle aspirate specimens from irradiated female Sprague-Dawley rats.Q51699567
Epithelial-mesenchymal transition and the invasive potential of tumors.Q51959766
MicroRNA profiling differentiates colorectal cancer according to KRAS status.Q54348636
Development of a microRNA-based molecular assay for the detection of papillary thyroid carcinoma in aspiration biopsy samples.Q54390446
Survival for eight major cancers and all cancers combined for European adults diagnosed in 1995–99: results of the EUROCARE-4 studyQ57192409
Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-TocopherolQ95780509
P433issue6
P921main subjectmicroRNAQ310899
P304page(s)e249-58
P577publication date2012-06-01
P1433published inLancet Oncology CommissionQ13747613
P1476titlemicroRNAs in cancer management
P478volume13

Reverse relations

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Q37681002Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis
Q36464885Predictive role of miR-146a rs2910164 (C>G), miR-149 rs2292832 (T>C), miR-196a2 rs11614913 (T>C) and miR-499 rs3746444 (T>C) in the development of hepatocellular carcinoma
Q57116698Prognostic Role of MicroRNA-497 In Cancer Patients: A Meta-analysis
Q30235175Prognostic Role of the MicroRNA-200 Family in Various Carcinomas: A Systematic Review and Meta-Analysis
Q45056241Prognostic evaluation of microRNA-210 expression in pediatric osteosarcoma
Q43847258Prognostic evaluation of microRNA-210 in various carcinomas: Evidence from 19 studies
Q39788725Prognostic impact of a 3-MicroRNA signature in cytological samples of small cell lung cancer
Q33275146Prognostic significance of miRNA-1 (miR-1) expression in patients with chordoma
Q44140172Prognostic significance of serum miR-17-5p in lung cancer
Q93018335Prognostic value of miR-221 in human malignancy: evidence from 3041 subjects
Q37584292Prospects of miRNA-based therapy for pancreatic cancer
Q45746024Quantitative assessment of the association between microRNA-499 rs3746444 A/G polymorphism and cancer risk
Q38975876RKIP suppresses gastric cancer cell proliferation and invasion and enhances apoptosis regulated by microRNA-224.
Q34776553Real-time monitoring of miRNA function in pancreatic cell lines using recombinant AAV-based miRNA Asensors
Q38790306Recent scenario of microRNA as diagnostic and prognostic biomarkers of prostate cancer
Q33599015Reciprocal regulation between microRNAs and epigenetic machinery in colorectal cancer
Q36963728Regulation of lung cancer metastasis by Klf4-Numb-like signaling
Q90634169Regulation of the small GTPase Ran by miR-802 modulates proliferation and metastasis in colorectal cancer cells
Q35113163Retracted: MicroRNA-214 Suppresses Oncogenesis and Exerts Impact on Prognosis by Targeting PDRG1 in Bladder Cancer
Q39165476Role of Wnt/β-catenin signaling regulatory microRNAs in the pathogenesis of colorectal cancer.
Q34993924Role of antiviral therapy in reducing recurrence and improving survival in hepatitis B virus-associated hepatocellular carcinoma following curative resection (Review)
Q33559304Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives.
Q38216239Role of microRNA in response to ionizing radiations: evidences and potential impact on clinical practice for radiotherapy.
Q41672604Roles of miR-138 and ISG15 in oral squamous cell carcinoma
Q35619400STAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells
Q40251268Screening of Target Genes and Regulatory Function of miRNAs as Prognostic Indicators for Prostate Cancer.
Q34004659Serum miRNA signature in Moyamoya disease
Q35087659Serum microRNA-21 as a potential biomarker for response to hypomethylating agents in myelodysplastic syndromes
Q37133785Signal transduction in the development of pulmonary arterial hypertension
Q49670471Small RNA sequencing profiles of mir-181 and mir-221, the most relevant microRNAs in acute myeloid leukemia.
Q42356986Small RNAs have a big effect on polycystic kidney disease
Q38972399Snail-regulated MiR-375 inhibits migration and invasion of gastric cancer cells by targeting JAK2.
Q91707587Specific miRNA expression profile in the blood serum of cardiac myxoma patients
Q38810089Study on the Association Between miRNA-202 Expression and Drug Sensitivity in Multiple Myeloma Cells
Q64102820Superparamagnetic iron oxide nanoparticle-mediated expression of inhibits human endometrial carcinoma stem cell growth
Q37225551Systematic evaluation of cancer risk associated with rs2292832 in miR‑149 and rs895819 in miR‑27a: a comprehensive and updated meta‑analysis
Q92258573Systems and Synthetic microRNA Biology: From Biogenesis to Disease Pathogenesis
Q37577414TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus
Q42777873TDP-43 regulates cancer-associated microRNAs.
Q55629415The Role of Curcumin in Prevention and Management of Metastatic Disease.
Q64060035The Role of MicroRNAs in Hepatoblastoma Tumors
Q37091920The Tumor Suppressor Roles of miR-433 and miR-127 in Gastric Cancer
Q38938079The Value of MiR-383, an Intronic MiRNA, as a Diagnostic and Prognostic Biomarker in Intestinal-Type Gastric Cancer
Q38891154The Value of miR-299-5p in Diagnosis and Prognosis of Intestinal-Type Gastric Adenocarcinoma.
Q39126198The anti-metastatic activity of collagenase-2 in breast cancer cells is mediated by a signaling pathway involving decorin and miR-21.
Q38755667The anti-oncogenic influence of ellagic acid on colon cancer cells in leptin-enriched microenvironment.
Q51310017The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucose.
Q45937007The clinical use of circulating microRNAs as non-invasive diagnostic biomarkers for lung cancers.
Q58754543The correlation between microRNA-221/222 cluster overexpression and malignancy: an updated meta-analysis including 2693 patients
Q38156047The emerging role of miR-375 in cancer
Q26740283The emerging role of miR-506 in cancer
Q34310378The epigenetics of epithelial-mesenchymal plasticity in cancer
Q39353707The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies
Q33798887The importance of the genomic landscape in Waldenström's Macroglobulinemia for targeted therapeutical interventions
Q59330317The miR-199a-3p regulates the radioresistance of esophageal cancer cells via targeting the AK4 gene
Q39202832The miR-30 family: Versatile players in breast cancer
Q45901790The microRNA-21/PTEN pathway regulates the sensitivity of HER2-positive gastric cancer cells to trastuzumab.
Q51764980The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer.
Q91792434The potential value of microRNA-4463 in the prognosis evaluation in hepatocellular carcinoma
Q26744149The role of microRNAs in bladder cancer
Q36396579The role of microRNAs in breast cancer migration, invasion and metastasis
Q64262299The rs4919510 G>C polymorphism confers reduce coronary injury of Kawasaki disease in a Southern Chinese population
Q38962587The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway
Q30411597The urine microRNA profile may help monitor post-transplant renal graft function
Q38310488Thinking small: towards microRNA-based therapeutics for anxiety disorders
Q34343614Tissue microRNAs as predictors of outcome in patients with metastatic colorectal cancer treated with first line Capecitabine and Oxaliplatin with or without Bevacizumab.
Q37212187U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis
Q39432577Understanding the Role of Non-Coding RNAs in Bladder Cancer: From Dark Matter to Valuable Therapeutic Targets.
Q34667439Upregulation of microRNA-106b is associated with poor prognosis in hepatocellular carcinoma
Q90424166Using microRNAs as Novel Predictors of Urologic Cancer Survival: An Integrated Analysis
Q33716038Versatile RNA interference nanoplatform for systemic delivery of RNAs.
Q35878681Vps4A functions as a tumor suppressor by regulating the secretion and uptake of exosomal microRNAs in human hepatoma cells
Q50999969[miR-202 contributes to sensitizing MM cells to drug significantly via activing JNK/SAPK signaling pathway].
Q47152865hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC.
Q89537628miR-100 Inhibits Cell Growth and Proliferation by Targeting HOXA1 in Nasopharyngeal Carcinoma
Q36132797miR-124 Regulates the Epithelial-Restricted with Serine Box/Epidermal Growth Factor Receptor Signaling Axis in Head and Neck Squamous Cell Carcinoma
Q37705826miR-124 represses the mesenchymal features and suppresses metastasis in Ewing sarcoma
Q37535463miR-126 functions as a tumor suppressor in osteosarcoma by targeting Sox2.
Q39059633miR-126 inhibits cell proliferation and induces cell apoptosis of hepatocellular carcinoma cells partially by targeting Sox2.
Q41473012miR-133b, a particular member of myomiRs, coming into playing its unique pathological role in human cancer
Q92939658miR-135a Inhibits the Invasion and Migration of Esophageal Cancer Stem Cells through the Hedgehog Signaling Pathway by Targeting Smo
Q38971368miR-137 effects on gastric carcinogenesis are mediated by targeting Cox-2-activated PI3K/AKT signaling pathway
Q39062167miR-137 impairs the proliferative and migratory capacity of human non-small cell lung cancer cells by targeting paxillin
Q38838174miR-137 suppresses the invasion and procedure of EMT of human breast cancer cell line MCF-7 through targeting CtBP1.
Q44055579miR-145 suppresses cell invasion in hepatocellular carcinoma cells: miR-145 targets ADAM17.
Q36545884miR-149 represses metastasis of hepatocellular carcinoma by targeting actin-regulatory proteins PPM1F
Q42322707miR-15b modulates multidrug resistance in human osteosarcoma in vitro and in vivo
Q36772022miR-16 targets fibroblast growth factor 2 to inhibit NPC cell proliferation and invasion via PI3K/AKT and MAPK signaling pathways
Q38855018miR-17 regulates melanoma cell motility by inhibiting the translation of ETV1.
Q37428692miR-203, a tumor suppressor frequently down-regulated by promoter hypermethylation in rhabdomyosarcoma.
Q38833391miR-205 suppresses the proliferative and migratory capacity of human osteosarcoma Mg-63 cells by targeting VEGFA.
Q34096085miR-21 promotes the differentiation of hair follicle-derived neural crest stem cells into Schwann cells
Q37582210miR-217 regulates tumor growth and apoptosis by targeting the MAPK signaling pathway in colorectal cancer
Q38780717miR-221/222 enhance the tumorigenicity of human breast cancer stem cells via modulation of PTEN/Akt pathway
Q91593318miR-221/222-Mediated Inhibition of Autophagy Promotes Dexamethasone Resistance in Multiple Myeloma
Q38093079miR-221/222: promising biomarkers for breast cancer
Q35023269miR-29b, miR-205 and miR-221 enhance chemosensitivity to gemcitabine in HuH28 human cholangiocarcinoma cells
Q88716794miR-301a plays a pivotal role in hypoxia-induced gemcitabine resistance in pancreatic cancer
Q52655303miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein.
Q35769117miR-34a and miR-125b Expression in HPV Infection and Cervical Cancer Development.
Q39091716miR-34a regulates cisplatin-induce gastric cancer cell death by modulating PI3K/AKT/survivin pathway
Q40985945miR-492G>C polymorphism (rs2289030) is associated with overall survival of hepatocellular carcinoma patients
Q38703593miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression
Q90526172miR-608 and miR-4513 significantly contribute to the prognosis of lung adenocarcinoma treated with EGFR-TKIs
Q35167131miR-630 overexpression in hepatocellular carcinoma tissues is positively correlated with alpha-fetoprotein
Q53627455miR-644a Inhibits Cellular Proliferation and Invasion via Suppression of CtBP1 in Gastric Cancer Cells.
Q38960051miR-99a suppresses the metastasis of human non-small cell lung cancer cells by targeting AKT1 signaling pathway
Q39028436miR181b is induced by the chemopreventive polyphenol curcumin and inhibits breast cancer metastasis via down-regulation of the inflammatory cytokines CXCL1 and -2.
Q51763083miR199a-5p inhibits hepatic insulin sensitivity via suppression of ATG14-mediated autophagy.
Q53508723miRNA-202 in bone marrow stromal cells affects the growth and adhesion of multiple myeloma cells by regulating B cell-activating factor.
Q53474022miRNA-214 Inhibits Cellular Proliferation and Migration in Glioma Cells Targeting Caspase 1 Involved in Pyroptosis.
Q92512023miRNA-574-3p inhibits metastasis and chemoresistance of epithelial ovarian cancer (EOC) by negatively regulating epidermal growth factor receptor (EGFR)
Q38187448miRNAs and their application in drug-induced liver injury
Q38365504miRNAs in inflammatory skin diseases and their clinical implications.
Q42546641miRNA‑504 inhibits p53‑dependent vascular smooth muscle cell apoptosis and may prevent aneurysm formation
Q55344720microRNA based prognostic biomarkers in pancreatic Cancer.
Q34920251microRNA-124 inhibits migration and invasion by down-regulating ROCK1 in glioma
Q38998609microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta
Q38366523p53, a translational regulator: contribution to its tumour-suppressor activity.

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