Long noncoding RNAs: a potential novel class of cancer biomarkers

scientific article published on 23 April 2015

Long noncoding RNAs: a potential novel class of cancer biomarkers is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FGENE.2015.00145
P932PMC publication ID4407501
P698PubMed publication ID25954300
P5875ResearchGate publication ID275352154

P2093author name stringIgor V Kurochkin
Aliaksandr A Yarmishyn
P2860cites workIdentification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectQ21061203
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Long noncoding RNA profiles identify five distinct molecular subtypes of colorectal cancer with clinical relevanceQ41135377
Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes.Q42458434
Plasma HULC as a promising novel biomarker for the detection of hepatocellular carcinomaQ43455162
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Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinomaQ44814250
Overexpression of long noncoding RNA HOTAIR predicts a poor prognosis in patients with cervical cancerQ45864331
Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantationQ46219683
Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissuesQ47930296
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.Q51856604
Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors.Q52181418
Alterations in promoter usage and expression levels of insulin-like growth factor-II and H19 genes in cervical carcinoma exhibiting biallelic expression of IGF-II.Q53670499
Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer.Q54200101
HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patientsQ57571046
Frequent loss of imprinting of the H19 gene is often associated with its overexpression in human lung cancersQ72119659
Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding siteQ73006826
Genomic imprinting of IGF2 and H19 in human meningiomasQ73594889
Gain of chromosome arm 17q and adverse outcome in patients with neuroblastomaQ77911604
DD3(PCA3), a very sensitive and specific marker to detect prostate tumorsQ78019707
Prostate cancer: diagnostic performance of the PCA3 urine testQ83586398
Salivary lncRNA as a potential marker for oral squamous cell carcinoma diagnosisQ85843721
Long non-coding RNA HOTAIR is a powerful predictor of metastasis and poor prognosis and is associated with epithelial-mesenchymal transition in colon cancerQ87904853
The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor PhosphorylationQ24297656
Activation of p53 by MEG3 non-coding RNAQ24310760
BRCA1 is a negative modulator of the PRC2 complexQ24339430
The imprinted H19 gene is a marker of early recurrence in human bladder carcinoma.Q24535316
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivatorQ24548002
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisQ24607308
The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expressionQ24608592
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcriptionQ24646744
Specific expression of long noncoding RNAs in the mouse brainQ24648944
Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptorQ24650793
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expressionQ24654249
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
Functionality or transcriptional noise? Evidence for selection within long noncoding RNAsQ24681496
The transcriptional landscape of the mammalian genomeQ27861110
Maternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progressionQ28115872
Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomasQ28117410
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammalsQ28131802
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAsQ28131821
Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinomaQ28140252
Overexpression of an ectopic H19 gene enhances the tumorigenic properties of breast cancer cellsQ28214006
The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesisQ28240820
Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAsQ28246401
Loss of H19 imprinting in esophageal cancerQ28273448
GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancerQ28296081
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 responseQ28592069
HOXD-AS1 is a novel lncRNA encoded in HOXD cluster and a marker of neuroblastoma progression revealed via integrative analysis of noncoding transcriptomeQ28652372
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosomeQ29547359
Landscape of transcription in human cellsQ29547467
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lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elementsQ29617832
Extracellular vesicles: exosomes, microvesicles, and friendsQ29618137
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancerQ29620125
Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.Q33269991
Prognostic significance of drug-regulated genes in high-grade osteosarcomaQ33292143
Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancerQ33613022
Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiolQ36920160
Knockdown of long non-coding RNA HOTAIR suppresses tumor invasion and reverses epithelial-mesenchymal transition in gastric cancerQ37001515
Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular CancerQ37253566
The H19 locus: role of an imprinted non-coding RNA in growth and development.Q37756737
microRNAs in cancer management.Q38015027
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Long noncoding RNA HOTAIR involvement in cancerQ38244306
Long noncoding RNA profiles reveal three molecular subtypes in gliomaQ38439094
Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencingQ38483181
The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiationQ38927720
Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibilityQ38947097
Down-regulation of ncRAN, a long non-coding RNA, contributes to colorectal cancer cell migration and invasion and predicts poor overall survival for colorectal cancer patientsQ39024684
A critical role for the long non-coding RNA GAS5 in proliferation and apoptosis in non-small-cell lung cancerQ39041604
Downregulation of gas5 increases pancreatic cancer cell proliferation by regulating CDK6.Q39096980
Large noncoding RNA HOTAIR enhances aggressive biological behavior and is associated with short disease-free survival in human non-small cell lung cancerQ39143065
Long non-coding RNA metastasis associated in lung adenocarcinoma transcript 1 derived miniRNA as a novel plasma-based biomarker for diagnosing prostate cancerQ39145196
Long non-coding RNA GAS5 functions as a tumor suppressor in renal cell carcinomaQ39159899
Inducing cell proliferation inhibition, apoptosis, and motility reduction by silencing long noncoding ribonucleic acid metastasis-associated lung adenocarcinoma transcript 1 in urothelial carcinoma of the bladderQ39244281
Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat.Q39259710
Upregulated MALAT-1 contributes to bladder cancer cell migration by inducing epithelial-to-mesenchymal transitionQ39327058
Large intervening non-coding RNA HOTAIR is associated with hepatocellular carcinoma progressionQ39404230
Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferationQ39414139
Long non-coding RNA expression profiles predict clinical phenotypes in gliomaQ39600563
ncRAN, a newly identified long noncoding RNA, enhances human bladder tumor growth, invasion, and survivalQ39621585
Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancerQ33618023
A long non-coding RNA signature to improve prognosis prediction of colorectal cancerQ33688589
GAS5 long non-coding RNA in malignant pleural mesothelioma.Q33690709
Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancerQ33729015
DD3: a new prostate-specific gene, highly overexpressed in prostate cancerQ33884277
High expression of lncRNA MALAT1 suggests a biomarker of poor prognosis in colorectal cancerQ33898623
Down-regulation of long non-coding RNA GAS5 is associated with the prognosis of hepatocellular carcinomaQ34029258
Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasionQ34102814
Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancerQ34143978
Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantationQ34165090
Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesiclesQ34173881
Cell-free nucleic acids as biomarkers in cancer patientsQ34184393
Transcribed dark matter: meaning or myth?Q34192913
DD3(PCA3)-based molecular urine analysis for the diagnosis of prostate cancerQ34206957
A genetic variant in long non-coding RNA HULC contributes to risk of HBV-related hepatocellular carcinoma in a Chinese populationQ34228585
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Q34278940
Elevated expression of PCGEM1, a prostate-specific gene with cell growth-promoting function, is associated with high-risk prostate cancer patientsQ34290030
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cellsQ34317898
Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genomeQ34324184
A long non-coding RNA signature in glioblastoma multiforme predicts survival.Q34347963
Phenotypic characterization of endometrial stromal sarcoma of the uterusQ34488858
Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinomaQ34558066
Repression of the human dihydrofolate reductase gene by a non-coding interfering transcriptQ34604327
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promotersQ34629890
Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasisQ34981188
Downregulation of GAS5 promotes bladder cancer cell proliferation, partly by regulating CDK6.Q34998951
The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancerQ35011288
Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.Q35013762
Enhanced expression of long non-coding RNA HOTAIR is associated with the development of gastric cancerQ35018720
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progressionQ35154249
Long noncoding RNA HOTAIR as an independent prognostic marker in cancer: a meta-analysisQ35232074
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer.Q36357062
LincRNA-p21 suppresses target mRNA translationQ36431717
Long noncoding RNA HOTAIR is a prognostic marker for esophageal squamous cell carcinoma progression and survivalQ36871225
P921main subjectbiomarkerQ864574
P304page(s)145
P577publication date2015-04-23
P1433published inFrontiers in GeneticsQ2499875
P1476titleLong noncoding RNAs: a potential novel class of cancer biomarkers
P478volume6

Reverse relations

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