Exosomes as carriers transporting long non‑coding RNAs: Molecular characteristics and their function in cancer (Review)

scientific article published on 05 June 2019

Exosomes as carriers transporting long non‑coding RNAs: Molecular characteristics and their function in cancer (Review) is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3892/MMR.2019.10340
P932PMC publication ID6625196
P698PubMed publication ID31173220

P50authorAndrzej BednarekQ59158630
Raneem HammouzQ86304370
Damian KołatQ92060369
P2093author name stringElżbieta Płuciennik
P2860cites workGlioma cells enhance angiogenesis and inhibit endothelial cell apoptosis through the release of exosomes that contain long non-coding RNA CCAT2.Q42835218
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PBMC and exosome-derived Hotair is a critical regulator and potent marker for rheumatoid arthritisQ87660291
Regulation of microvascularization in heart failure - an endothelial cell, non-coding RNAs and exosome liaisonQ91214823
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Long Noncoding RNAs as Novel Biomarkers Have a Promising Future in Cancer DiagnosticsQ26753032
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Long non-coding RNA GAS5 regulates apoptosis in prostate cancer cell linesQ39151560
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The human long non-coding RNA-RoR is a p53 repressor in response to DNA damageQ39233244
Characterization of BCAR4, a novel oncogene causing endocrine resistance in human breast cancer cellsQ39555908
Overexpression of long non-coding RNA HOTTIP increases chemoresistance of osteosarcoma cell by activating the Wnt/β-catenin pathwayQ39652903
Exosomal Long Noncoding RNAs are Differentially Expressed in the Cervicovaginal Lavage Samples of Cervical Cancer Patients.Q39762381
Exosomal lncRNA-p21 levels may help to distinguish prostate cancer from benign diseaseQ40349500
Lung cancer exosomes as drivers of epithelial mesenchymal transitionQ40673503
Hypoxic exosomes facilitate bladder tumor growth and development through transferring long non-coding RNA-UCA1.Q41542110
Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes.Q42458434
Tetraspanins in viral infections: a fundamental role in viral biology?Q27470936
Exosomes isolation and characterization in serum is feasible in non-small cell lung cancer patients: critical analysis of evidence and potential role in clinical practiceQ28066211
The role of extracellular vesicles in mediating progression, metastasis and potential treatment of hepatocellular carcinomaQ28066407
Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applicationsQ28081849
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAsQ28131821
Exosomes: from biogenesis and secretion to biological functionQ28270550
GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancerQ28296081
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SNORD-host RNA Zfas1 is a regulator of mammary development and a potential marker for breast cancerQ28308175
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The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung AdenocarcinomaQ28547372
The complete exosome workflow solution: from isolation to characterization of RNA cargoQ28662332
RNA maps reveal new RNA classes and a possible function for pervasive transcriptionQ29614334
Molecular mechanisms of long noncoding RNAsQ29618027
Long non-coding RNA PARTICLE bridges histone and DNA methylationQ33687024
Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancerQ33729015
Exosome in tumour microenvironment: overview of the crosstalk between normal and cancer cells.Q33746697
Long Noncoding RNAs as Biomarkers in CancerQ33786847
Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodiesQ34035888
The imprinted H19 lncRNA antagonizes let-7 microRNAs.Q34038293
Function of PCA3 in prostate tissue and clinical research progress on developing a PCA3 scoreQ34130249
Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesiclesQ34173881
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cellsQ34317898
Databases for lncRNAs: a comparative evaluation of emerging toolsQ34363848
Involvement of extracellular vesicle long noncoding RNA (linc-VLDLR) in tumor cell responses to chemotherapyQ34364727
Heparanase activates the syndecan-syntenin-ALIX exosome pathwayQ35291841
Noncoding RNA as therapeutic targets for hepatocellular carcinoma.Q35592207
The roles of tumor-derived exosomes in cancer pathogenesisQ35606520
A central role for long non-coding RNA in cancerQ35757646
Expression of the Long Non-Coding RNA HOTAIR Correlates with Disease Progression in Bladder Cancer and Is Contained in Bladder Cancer Patient Urinary ExosomesQ35901823
CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA.Q35954464
Exosomes-mediated transfer of long noncoding RNA ZFAS1 promotes gastric cancer progressionQ36305421
Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathwayQ36517652
The regulation of cancer cell migration by lung cancer cell-derived exosomes through TGF-β and IL-10Q36524867
Unraveling the physiological functions of exosome secretion by tumorsQ36643644
Tumour exosome integrins determine organotropic metastasis.Q36677568
Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1)Q36729372
Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21.Q36843820
Emerging roles of exosomes in cancer invasion and metastasisQ37021889
Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular CancerQ37253566
Salivary HOTAIR and PVT1 as novel biomarkers for early pancreatic cancerQ37295361
Increased expression of long-noncoding RNA ZFAS1 is associated with epithelial-mesenchymal transition of gastric cancerQ37361038
LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancerQ37437309
YKT6 expression, exosome release, and survival in non-small cell lung cancer.Q37588313
Modulation of hypoxia-signaling pathways by extracellular linc-RoR.Q37674697
ESCRT & Co.Q37707470
Exosomal long noncoding RNA CRNDE-h as a novel serum-based biomarker for diagnosis and prognosis of colorectal cancerQ37709184
Long Non-Coding RNA as Potential Biomarker for Prostate Cancer: Is It Making a Difference?Q37724539
BC-819, a plasmid comprising the H19 gene regulatory sequences and diphtheria toxin A, for the potential targeted therapy of cancersQ37795679
The fusion of two worlds: non-coding RNAs and extracellular vesicles--diagnostic and therapeutic implications (Review).Q38262017
Long noncoding RNAs: a potential novel class of cancer biomarkersQ38466810
Long non-coding RNA and tumor hypoxia: new players ushered toward an old arenaQ38645336
Form and Function of Exosome-Associated Long Non-coding RNAs in CancerQ38688990
Serum long non coding RNA MALAT-1 protected by exosomes is up-regulated and promotes cell proliferation and migration in non-small cell lung cancerQ38700071
Glioma cells promote angiogenesis through the release of exosomes containing long non-coding RNA POU3F3.Q38710814
Inhibition of long non-coding RNA ROR reverses resistance to Tamoxifen by inducing autophagy in breast cancerQ38716017
Long non-coding RNA TUG1 can promote proliferation and migration of pancreatic cancer via EMT pathwayQ38724521
Perspectives of long non-coding RNAs in cancerQ38732979
Characters, functions and clinical perspectives of long non-coding RNAsQ38737055
Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA.Q38775160
The emerging roles of exosomes in tumor-stroma interactionQ38778513
Double-negative feedback loop between long non-coding RNA TUG1 and miR-145 promotes epithelial to mesenchymal transition and radioresistance in human bladder cancer cellsQ38839771
PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation.Q38883808
Long noncoding RNA ANRIL promotes non-small cell lung cancer cell proliferation and inhibits apoptosis by silencing KLF2 and P21 expressionQ38928640
Syntenin: Key player in cancer exosome biogenesis and uptake?Q38944832
Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2.Q39014592
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivativesQ6937225
P433issue2
P921main subjectneoplasmQ1216998
neoplastic gene expression regulationQ66660300
long non-coding RNAQ15087973
P304page(s)851-862
P577publication date2019-06-05
2019-08-01
P1433published inMolecular Medicine ReportsQ26842180
P1476titleExosomes as carriers transporting long non‑coding RNAs: Molecular characteristics and their function in cancer (Review)
P478volume20

Reverse relations

cites work (P2860)
Q97884627Advances in the role of exosomal non-coding RNA in the development, diagnosis, and treatment of gastric cancer (Review)
Q90047604Exosomes: From Potential Culprits to New Therapeutic Promise in the Setting of Cardiac Fibrosis

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