Nuclear import of the influenza A virus transcriptional machinery.

scientific article published on 29 May 2012

Nuclear import of the influenza A virus transcriptional machinery. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.VACCINE.2012.04.085
P698PubMed publication ID22652398
P5875ResearchGate publication ID225087692

P50authorEdward C HutchinsonQ56547259
Ervin FodorQ60680669
P2093author name stringE C Hutchinson
P2860cites workTransport between the cell nucleus and the cytoplasmQ22065411
Nuclear envelope permeabilityQ22122423
Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domainsQ24292247
Role of ran binding protein 5 in nuclear import and assembly of the influenza virus RNA polymerase complexQ24673668
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNAQ27640425
Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunitQ27643860
Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine designQ27651106
Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase PB2 SubunitQ27651972
Structural Basis of the Influenza A Virus RNA Polymerase PB2 RNA-binding Domain Containing the Pathogenicity-determinant Lysine 627 ResidueQ27653426
Receptor binding and membrane fusion in virus entry: the influenza hemagglutininQ27861017
An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoproteinQ27863807
Functional association between viral and cellular transcription during influenza virus infectionQ27863933
Nuclear traffic of influenza virus proteins and ribonucleoprotein complexesQ27864127
Nuclear import of influenza virus RNA can be mediated by viral nucleoprotein and transport factors required for protein importQ27865295
The NPI-1/NPI-3 (karyopherin alpha) binding site on the influenza a virus nucleoprotein NP is a nonconventional nuclear localization signalQ27867699
Molecular basis for specificity of nuclear import and prediction of nuclear localizationQ28296734
NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoproteinQ28306037
Two signals mediate nuclear localization of influenza virus (A/WSN/33) polymerase basic protein 2Q28646305
Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteinsQ28646344
Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemicQ29619055
The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host.Q30352150
Host restriction of avian influenza viruses at the level of the ribonucleoproteins.Q30371993
Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy.Q30382441
Adaptive strategies of the influenza virus polymerase for replication in humansQ30383307
Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virusQ30398701
Interaction of polymerase subunit PB2 and NP with importin alpha1 is a determinant of host range of influenza A virusQ33318082
The host-dependent interaction of alpha-importins with influenza PB2 polymerase subunit is required for virus RNA replicationQ33391385
Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.Q34055461
Ultrastructural analysis of the nuclear localization sequences on influenza A ribonucleoprotein complexesQ81538388
RIG-I detects viral genomic RNA during negative-strand RNA virus infectionQ34097840
Trafficking of viral genomic RNA into and out of the nucleus: influenza, Thogoto and Borna disease virusesQ34223092
Heat shock protein 70 is related to thermal inhibition of nuclear export of the influenza virus ribonucleoprotein complexQ35543072
Involvement of Hsp90 in assembly and nuclear import of influenza virus RNA polymerase subunitsQ35635186
Nuclear import of influenza A viral ribonucleoprotein complexes is mediated by two nuclear localization sequences on viral nucleoproteinQ35840594
Nuclear trafficking of influenza virus ribonuleoproteins in heterokaryonsQ35859787
Globin mRNAs are primers for the transcription of influenza viral RNA in vitroQ35994818
Influenza A virus and the cell nucleusQ36522223
Function of two discrete regions is required for nuclear localization of polymerase basic protein 1 of A/WSN/33 influenza virus (H1 N1)Q36719935
Storage of cellular 5' mRNA caps in P bodies for viral cap-snatchingQ37039521
Avian Influenza A virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infectionQ37051652
A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA.Q37275127
Attenuated strains of influenza A viruses do not induce degradation of RNA polymerase II.Q37410776
The role of the influenza virus RNA polymerase in host shut-offQ37823112
Characterization of the interaction between the influenza A virus polymerase subunit PB1 and the host nuclear import factor Ran-binding protein 5.Q39544562
The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virus RNA polymerase complexQ39755896
Mechanisms and functional implications of the degradation of host RNA polymerase II in influenza virus infected cellsQ39781908
Nuclear dynamics of influenza A virus ribonucleoproteins revealed by live-cell imaging studiesQ39801069
Differential polymerase activity in avian and mammalian cells determines host range of influenza virusQ40120171
Influenza virus infection causes specific degradation of the largest subunit of cellular RNA polymerase II.Q40162019
Identification of cellular interaction partners of the influenza virus ribonucleoprotein complex and polymerase complex using proteomic-based approachesQ40176125
In vitro assembly of PB2 with a PB1-PA dimer supports a new model of assembly of influenza A virus polymerase subunits into a functional trimeric complexQ40409573
Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II.Q40435957
Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoproteinQ40648738
Several protein regions contribute to determine the nuclear and cytoplasmic localization of the influenza A virus nucleoproteinQ40905176
The directionality of the nuclear transport of the influenza A genome is driven by selective exposure of nuclear localization sequences on nucleoproteinQ41549176
Nuclear transport of influenza virus polymerase PA protein.Q41622854
Detection and characterization of influenza A virus PA-PB2 interaction through a bimolecular fluorescence complementation assayQ42107951
Synthesis and cellular location of the ten influenza polypeptides individually expressed by recombinant vaccinia virusesQ43756587
Influenza virus, an RNA virus, synthesizes its messenger RNA in the nucleus of infected cellsQ44038116
The role of nuclear import and export in influenza virus infectionQ44303965
Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein.Q44399562
Hsp90 inhibitors reduce influenza virus replication in cell cultureQ45394243
Influenza virus inhibits RNA polymerase II elongationQ45417487
A classical bipartite nuclear localization signal on Thogoto and influenza A virus nucleoproteinsQ45753472
Complex structure of the nuclear translocation signal of influenza virus polymerase PA subunitQ45779598
Pathogenicity of influenza A/Seal/Mass/1/80 virus mutants for mammalian speciesQ45786362
Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virusQ45791146
Influenza virus RNA is synthesized at fixed sites in the nucleusQ45793002
Identification of the sequence responsible for the nuclear accumulation of the influenza virus nucleoprotein in Xenopus oocytesQ45828989
Nuclear transport of influenza virus ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits importQ45854241
P433issue51
P407language of work or nameEnglishQ1860
P921main subjectinfluenza A virusQ834390
travel-associated infectionQ55107495
P304page(s)7353-7358
P577publication date2012-05-29
P1433published inVaccineQ7907941
P1476titleNuclear import of the influenza A virus transcriptional machinery
P478volume30

Reverse relations

cites work (P2860)
Q35006697A comprehensive map of the influenza A virus replication cycle
Q30429748Adaptation of avian influenza A virus polymerase in mammals to overcome the host species barrier
Q38111647Adaptive mutations in the H5N1 polymerase complex
Q41909154Adaptive mutations in the nuclear export protein of human-derived H5N1 strains facilitate a polymerase activity-enhancing conformation
Q39226164Annotating Protein Functional Residues by Coupling High-Throughput Fitness Profile and Homologous-Structure Analysis
Q38117553Biogenesis, assembly, and export of viral messenger ribonucleoproteins in the influenza A virus infected cell
Q28085400Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part I: Influenza life-cycle and currently available drugs
Q30432421Emerging antiviral strategies to interfere with influenza virus entry
Q37214687Exploration of binary virus-host interactions using an infectious protein complementation assay
Q36969187Expression of importin-α isoforms in human nasal mucosa: implication for adaptation of avian influenza A viruses to human host.
Q36736357Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein
Q45323947Identification of a novel compound targeting the nuclear export of influenza A virus nucleoprotein
Q30385766Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import.
Q30393838Interaction of Host Nucleolin with Influenza A Virus Nucleoprotein in the Early Phase of Infection Limits the Late Viral Gene Expression
Q30366402Interactome analysis of the influenza A virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication.
Q30361315Large-scale analysis of influenza A virus nucleoprotein sequence conservation reveals potential drug-target sites.
Q36384462Mapping the phosphoproteome of influenza A and B viruses by mass spectrometry
Q30364868Molecular determinants of influenza virus pathogenesis in mice.
Q42197519Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2.
Q26852688Nucleocytoplasmic shuttling of influenza A virus proteins
Q38130587Nucleocytoplasmic shuttling of viral proteins in borna disease virus infection
Q30429005Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein
Q35641136Phosphorylation controls the nuclear-cytoplasmic shuttling of influenza A virus nucleoprotein
Q35122867PmVRP15, a novel viral responsive protein from the black tiger shrimp, Penaeus monodon, promoted white spot syndrome virus replication
Q45326218RNA structure interactions and ribonucleoprotein processes of the influenza A virus
Q61800032Real-time dissection of dynamic uncoating of individual influenza viruses
Q47094704Structural analysis of the complex between influenza B nucleoprotein and human importin-α.
Q91983829The Extended C-Terminal Region of Influenza C Virus Nucleoprotein Is Important for Nuclear Import and Ribonucleoprotein Activity
Q28084418The RNA synthesis machinery of negative-stranded RNA viruses
Q45353496The nuclear import machinery is a determinant of influenza virus host adaptation
Q37271683Transport of the influenza virus genome from nucleus to nucleus
Q57093653Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview

Search more.